Basic Information

Insect: Culex pipiens
Gene Symbol: -
Assembly: GCA_016801865.2
Location: NC:14501636-14513608[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 27 0.11 3.5 8.8 1.1 2 23 213 235 213 235 0.90

2 27 0.87 27 6.0 0.4 1 19 249 267 249 269 0.85

3 27 0.012 0.37 11.9 0.2 1 20 383 402 383 404 0.94

4 27 4.6 1.4e+02 3.7 0.1 2 23 411 433 410 433 0.93

5 27 8 2.5e+02 3.0 0.1 1 11 563 573 563 584 0.82

6 27 0.4 12 7.1 0.5 1 21 591 611 591 612 0.96

7 27 0.61 19 6.5 0.2 2 23 640 662 640 662 0.94

8 27 0.062 1.9 9.6 2.9 1 22 675 696 675 696 0.94

9 27 6.6 2e+02 3.2 4.0 2 20 795 813 794 815 0.92

10 27 1.2 38 5.5 0.0 1 23 823 845 823 845 0.96

11 27 0.038 1.2 10.3 2.7 1 21 851 871 851 873 0.94

12 27 5.1e-05 0.0016 19.3 1.7 1 23 878 901 878 901 0.96

13 27 0.085 2.6 9.2 5.3 1 23 906 928 906 928 0.97

14 27 0.00043 0.013 16.4 4.7 1 23 965 987 965 987 0.98

15 27 0.00061 0.019 15.9 0.1 1 20 993 1012 993 1014 0.94

16 27 0.48 15 6.8 1.1 1 23 1499 1521 1499 1521 0.97

17 27 0.0013 0.04 14.9 0.3 2 20 1533 1551 1532 1553 0.93

18 27 1.3 41 5.4 0.2 1 23 1561 1583 1561 1583 0.97

19 27 0.92 28 5.9 2.1 1 22 1599 1621 1599 1623 0.84

20 27 0.0015 0.046 14.7 0.3 2 22 1641 1661 1640 1661 0.95

21 27 0.76 23 6.2 1.2 1 19 1668 1686 1668 1690 0.81

22 27 1.1e-05 0.00032 21.5 3.1 1 23 1696 1718 1696 1718 0.98

23 27 0.0023 0.072 14.1 0.5 1 23 1724 1746 1724 1746 0.97

24 27 0.0022 0.067 14.2 5.7 1 23 1753 1775 1753 1775 0.98

25 27 0.074 2.3 9.4 5.2 1 23 1781 1803 1781 1803 0.97

26 27 0.097 3 9.0 2.2 1 23 1837 1859 1837 1859 0.94

27 27 0.00016 0.0051 17.7 0.3 1 23 1865 1889 1865 1889 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	27	0.11	3.5	8.8	1.1	2	23	213	235	213	235	0.90
2	27	0.87	27	6.0	0.4	1	19	249	267	249	269	0.85
3	27	0.012	0.37	11.9	0.2	1	20	383	402	383	404	0.94
4	27	4.6	1.4e+02	3.7	0.1	2	23	411	433	410	433	0.93
5	27	8	2.5e+02	3.0	0.1	1	11	563	573	563	584	0.82
6	27	0.4	12	7.1	0.5	1	21	591	611	591	612	0.96
7	27	0.61	19	6.5	0.2	2	23	640	662	640	662	0.94
8	27	0.062	1.9	9.6	2.9	1	22	675	696	675	696	0.94
9	27	6.6	2e+02	3.2	4.0	2	20	795	813	794	815	0.92
10	27	1.2	38	5.5	0.0	1	23	823	845	823	845	0.96
11	27	0.038	1.2	10.3	2.7	1	21	851	871	851	873	0.94
12	27	5.1e-05	0.0016	19.3	1.7	1	23	878	901	878	901	0.96
13	27	0.085	2.6	9.2	5.3	1	23	906	928	906	928	0.97
14	27	0.00043	0.013	16.4	4.7	1	23	965	987	965	987	0.98
15	27	0.00061	0.019	15.9	0.1	1	20	993	1012	993	1014	0.94
16	27	0.48	15	6.8	1.1	1	23	1499	1521	1499	1521	0.97
17	27	0.0013	0.04	14.9	0.3	2	20	1533	1551	1532	1553	0.93
18	27	1.3	41	5.4	0.2	1	23	1561	1583	1561	1583	0.97
19	27	0.92	28	5.9	2.1	1	22	1599	1621	1599	1623	0.84
20	27	0.0015	0.046	14.7	0.3	2	22	1641	1661	1640	1661	0.95
21	27	0.76	23	6.2	1.2	1	19	1668	1686	1668	1690	0.81
22	27	1.1e-05	0.00032	21.5	3.1	1	23	1696	1718	1696	1718	0.98
23	27	0.0023	0.072	14.1	0.5	1	23	1724	1746	1724	1746	0.97
24	27	0.0022	0.067	14.2	5.7	1	23	1753	1775	1753	1775	0.98
25	27	0.074	2.3	9.4	5.2	1	23	1781	1803	1781	1803	0.97
26	27	0.097	3	9.0	2.2	1	23	1837	1859	1837	1859	0.94
27	27	0.00016	0.0051	17.7	0.3	1	23	1865	1889	1865	1889	0.97

Sequence Information

Coding Sequence: ATGGACCAACCCGGCGGTCCGCGACGGCCCAAGATGTGCCGCGTTTGTCGCGCTCCGGACAACGACGATCTTATCACGGTGCAGCTGGTGCAGGAAGGCGTCTCAGTCGCCACCATGTTTCTCGAGCTGACGGGAATTCAGGTCACAGCGGACCGTAACCTACCCCAGAATGTGTGCCTCGCGTGTCTGGAGCGACTTCGGAGCGCACACCTGCTACGCCGCCAATGTCTCGAATCGGACCAGCTGCTGCGGGGTGAACTTCCGGTTGCTACTCCCGCTCCGAAGGAGGTTGAGGTTGAAACTGTGCCGAAAGTTGCGAAACCACCCCCTCATTTAGAGGAACCCACAGGGATGTTCAAGCTGGAAATTGAAACGCTCGAGATTGAGTCGGAACCGGAAGAGGTCGTCTGTGAggccgaggaggaggaggaaaacGAGTTGAAGTTCATCGTGGAGAGTGTGGACGAAGTTGAAGAGGAGGGAGACGACCAAACGATTGACATTTTAACGGCGGAGGAGCAACCGGACGAGCAGGTTAAGCAATCGGATGTGATGTACCTGAACAGCTACGACGAGTCGGATTACGAGATTGTCTACCAGGGGGAACACTACGACCGGATTAAATTTATCGTGGCGCGATGCTGCGGTTGTTCGAGGCGGTTTCCGAACAAAACGGAACTGCTGGAGCATGGTCAGGCGGTGCATAAGGCGCACAATCAGAAGCCTGCGAAGCGAAACTTTCCCCACGAGTGTCCGGTTTGCTTCCGGCAGTTTACGAGCAAGCGTGCGGTTGGGGATCATCGCGACCAGATCGACACGGACTGGTTCCACTGTCGGGAGTGTGACCTGCTGGTGCACAGTCAGCGGCAAATCGAGGGTCATTTGGAGCGGGTTCATGGAATTACGGAGATGGAGGGTGAGAGTGAAGAAGATGGAGACGAGGAACACGGTGCGGCGTTGACGCTGGCAGCGTTCGATCCGAGTCAGTACGAGCTGACGCGCACCGAGTTTGGGTTCGACCTGGTAGAGTTTACCTGTTGGCGGTGCTGCGGATGTTTGGCCAGTTTCGAGCTGCGAGAGGATTTCGAACAGCACTCGCGCGAGCAGCATCTGCCGGAGCGAAGGGAGGAGGATGGAGACCGGCCGTACGAGTGCAACATTTGCTATCGGAGATTCGAGAAGCGGGCGTCGTTGATGATTCACAAAAATGGGCCAAAGAAGCGGCGCGTGGTTTGTCGAATTTGCGAGGGTATCTTCCGGGGGGAGACGACCTACCGGAAGCATGCGTTGAAGGAGCACGGGATGGTGAACGATGGTGAGGACGCCGGAGATGTCAGCATGCAGGACGTGGAGTTTATCGAGGAACCGCTGGAAGAGGTGGGCCAGGTTCAGGAGATTAGCGATGGCGaggaagatgatgatgatgaggacGATGATGATCGGGAAGTAACGGGCAAGTACAGCAAATACAACTCGAGCAAGCAGCGCAAGGAGATGGGGCGGGTGCCGTGGAATCTGCTACGGACGGTTGAGGAGCTGGACGGGTACAACGTGGTGGAGATCTTGAAGGAGCGTTGCTGcaactgtttgcagtttttcgattcgGTTGAGGAACTTCACGAGCATACGCAGGTCCACCGGCAGGAAGCGCTGGCGGAAGCGGCCTGTTCCAGCAAACCGATCAAGTACCAGTGCGAGTTCTGCTTGAAGAGCTTCGACCTGGCTCTGGTCTACGTGGTCCATAAGCGAATTCGCGAACAGCGCCAGTTCTACCAGTGTCGGTTGTGCGATTTCGTGATCGATTCCGAGTCCCGGCTGAAGAATCACATGCTGCACAACGATCAGCACGCCAAGTTCTTCAACCTGATCCGGGAGGACGTCAGCGATCGGTACTATGCGGCCAGTCTACCGGGCGCACGGTGCTGCGGCTGTGGTCAGTACTTTGACGGCGAGGATGCGCTGGAGGAACATTCCCGGGCGGTGCACCCGCGAGATCCGGCCAAGGAGAGTACGAAGCGGACGCATAGTTGTAGAATCTGCGGCAAGCGTTGTTATAACCGTTCAGACGTGCTGATTCACCAGAAAAAGAACGGATCAACGGTGCGGTACTACTGTAAGCTGTGTGACTTTGAAACGGCCAACGAACCTCGGATGTTGAAGCATCTGTACAGTTCGATCCACAACGAGGCGTTCCCGGCGATTGAGGTGAAGAATATCGAGATTGGCTACAAGAAGGCCGGAGTTATTCGGTACTGCTGCTTCGAAGGTTGTCATCTTCCGTTCCACGACCACCAGAAGTTGTTTGACCACGTTGACGAACTTCATCTAGCGCAAAAGGCCCGCAACTTGGACGCGGTTGATCAGCAAACGGGGAACCGACTTCAGTGCGACTGTTGTCACCTGCACTTCCGAACGCTAACCCTGCTCAAGCAGCACCAAAGTGGCAACCAGCGACCGCTCAAAAGTTACGTCTGCTCCGTTTGTGGCCTCGCCAAACCAAGCAAAGCCGCCCTCGCCACCCACGAACTCCGTCACACCGGTGCGCGTCCCTACCCGTGCACCGTCTGCGACAAACGCTTCTCCTCGACGACCATCCTGAACTCGCACATGAAGTGCCACGCCCCCAAGCAGTACCAGTGCATCGAATGCGGAGAAAAGTTTGCCCGCAGCGAGAACCTCAAGCGTCACATCCGGCACCGGCACGCCGAGGCCACCTTCTGCTGCAGCTACTGTCCGCACAAGTCCAAGACCCGCGAAGCGCTGAACCAGCACGAGCGTTCGCACACCAAAGAGAAACCCTTCGAGTGCCGCTCCGAGGGCTGTCAAAAGCGATACGCCAGCATCTGTGACCGGAGACGGCACGAAATGGCCAGCCACACGGGCGAGAGACCCCACCAGTGTGACCACTGCACGGCTTCCTTTGTCCGCAAACGGCAGCTTACGATTCACGTTCGAAAGCACACCGGAGAGCGGCCCTTTGTGTGCTTAAAGTGTGGCAAAGGCTTCATCGATTCGGCTCTGCTGAAGAAACACACCTCCGTCACTTTCGCCGTCGTTATTGGCCCTGGTAGCTTTCACCACCTGCTTCAGGTCGACCTGCAGCGGACTCACGACAAACCGCACCTTGACCACGTCCTCATGCCCGTGGGCGTACCCGTACTCCGCCAGCTGGTTCCACCGGATgtgaaagttgaaaaagttgcgCTGATTGAGCTGGACGTTCCGCTCGAAGGCGGTGTGCTTCTCGCAGCCACCGTCCGGGTGGCCGAGCTCAAAGTCTGCAAATTCGTGATTGCCGTGGATGCCAATCTTCCAAACGGAACCGAACTGGTCCGTGTACTGCTGGTAGTCGGGGTTCTCCAAATCCGTGACAGAATAGTTATCAATGTGATAATTGAAGCAGTCGCCGTTGCCCTTAAGCCGTTGCGTTCGACTGGTTCGTTTGTTGAGCAATCGCTGTTGAATCTGAACTTTAGCTTTGAAATCCGCTGGACGGATTGTGTACCGGAAGCGCAGGTCAAACCTTCCCGGCGGCAGCGTTCGCTTGTCCAAAAAGTTCGGCACGCCCACGTATGCATCGTGGCCAATCCGGTCCCGCACCAGGAACGCCAACGGAGCAACGTTCTGCAACTCCAGCAGAACCTCGTAGAACCCTTCCTCGCCGTACAGCAACTCCACGAACGCGCCCAACTGTTGCTCCCGACCCTTCCCAACCTTAATCCTCAGCCGCCACTTGAAGCCCAACTCGTCCACGACATGTTCCGAGCAAACCCAGGCCAACCGACACCCGTGGACGTTCCGCAGCGTAAAGGTTCCCTCAACCGCTCGCGGTACCCCCAAAACAGGCTCCGTCCTACCCACCTCAACGTGTCGCGTTTCAGTCCGATGGCAATCGACCGGCGCCGCAGCCGGCGGTGCCACAATCAACCCGGAACTCCCCGCACCAATGTTCAAACACCCGTCACAACCATGAAGATCTGCCGGATCTGCATGCAGGGCGACGAGGACCGCCCCCTCCAGTCAATCTTCTCCCAAACCGACGGCGCCCACCTCGCGGAAACGGTCGCCGCAAGCTGTTCGCTCGAGCTCGCCACCGAGGACGACGGCCTGCCCGGTCAGATTTGCGCGCCGTGCGTGCGTGACGTCCAGCAGGTTGCGACGTTCCGAGAGCGGGCGCGCGAATCCGACCGCAAGCTGAGGCAGGTCGGTGCGTCTGGCGGAGGCGACTTTGAGGTGGTGGTCGTCAAGACGGAATCGATGGGGGAGGATGACGATGATCGGGAAGGCTTCAACTTGGGGCAATCCGAGTCGGATTCGGAAGATGATAGGCCGTTGAAGCGGCGGCGTCGAGTGAAAGCGTCGAGTTCCGATGACGAGGAGTTTACTGTGATTAAGGTCACACGGAAAAGTAAGCAAGTGGAGAGCGATTCTGACGACGAGCTGGACGTCAAAACGCTGTCAATGTTCGAGGAGGTTGCCCTGCCGGAAGGTAGCTACGTGTGTTGCAGCTGCTACAAGCACTTTGACAGCGTGGCCGCGCTCGAGCTACACGTGGAAGTTCACAAACGGCACGCCGTTAAACGGAGTGATTGCATTTATTGCGAGATCTGCAAGCGGAAATTTAAGAAAGAGTCAGCGCTGAAACGGCACGTGGCCAAGGTTAGCGCGCTAACCAAGCTGTACGAATGTGTGCAGTGCAACGTTCGGTTCATGAACGCCGCTGGACGGCGAATGCATGCCCAACGGCATCCGCAGAAAATCGAGGAGAAAATGAAGCAAGAATTTGGCGAGATTTTTTGTTGCGTTCAGAATTGCTCCAAGTCGTTTACTTCCGAGCAGTTGCTCATCGAGCATGGCCACGAGGCTCATCGGATCAACAAGCAAGCGTACGAGCTGGAAGACTCAACGCTGAAACCGATCGAATGTCCGGTTTGCTTTAAAAAGTTTGCCTCGGAACAGTTGCTTAGGCGGCATCGTCGACGGAACTCGCAACCCCTGAACCATCAATGTGCCACGTGTGGTCTCAAGTTCCGCACCAAGGACGTCTTGTCCTTCCACGAGCTTAACCACTCTGAAAAGAAGCCCTTCCCGTGCGATATCTGCCAGAAGCACTTTTCCAGCAAAAACTCGCTTAAAGTTCACCAGCGTAGTCACTCAAACGATAAGCCGTTCATTTGTTCGACCTGCGGAGCCCGGTTCTACCAGAAGGCCCAACTCGTCACCCACGAGTACACCCACCAGGACGGACCGCTCCCATTCCGGTGTGAAACCTGCTCCAAGTACTGCAAAACGAAGAACGCCCTCCGCAATCACATGCGCCAGCATACGGGCGAAAAGCCGTATCCCTGCCGGCACTGTTCAATCTCCTTTTCGAACCACACGAACCGCCAGCGGCACGAGATGAATCACACCGGAAACAAGCCCTTTGCGTGCTCGTTCTGCGACCGGAAGTTTACGATCAACCGGCTGAAGCTGGAGCACGAGTGCAAACACACCGGCGTTAAGCCGTTCAAATGTAGCTTCTGCGAGAAGTCGTTCATCCGGAAGCGGTTCCAGCTGGACCACGAGGCTACCCATACAGgcGAGAAGCCGTACCGCTGCGAAGTTCCGTCCTGTAATCGCACGTTCAGTCAGCAGGCACCGCTCAGGAGGCACATGGTAACGCACCGGACGGAAGGTAGTGCGGAATCTACTGCAGAATTCTTCCCATTGAATCAACAGACTCCGAATGTAAGCATATTGCCGCCCTCGTCATCGGTTTGA
Protein Sequence: MDQPGGPRRPKMCRVCRAPDNDDLITVQLVQEGVSVATMFLELTGIQVTADRNLPQNVCLACLERLRSAHLLRRQCLESDQLLRGELPVATPAPKEVEVETVPKVAKPPPHLEEPTGMFKLEIETLEIESEPEEVVCEAEEEEENELKFIVESVDEVEEEGDDQTIDILTAEEQPDEQVKQSDVMYLNSYDESDYEIVYQGEHYDRIKFIVARCCGCSRRFPNKTELLEHGQAVHKAHNQKPAKRNFPHECPVCFRQFTSKRAVGDHRDQIDTDWFHCRECDLLVHSQRQIEGHLERVHGITEMEGESEEDGDEEHGAALTLAAFDPSQYELTRTEFGFDLVEFTCWRCCGCLASFELREDFEQHSREQHLPERREEDGDRPYECNICYRRFEKRASLMIHKNGPKKRRVVCRICEGIFRGETTYRKHALKEHGMVNDGEDAGDVSMQDVEFIEEPLEEVGQVQEISDGEEDDDDEDDDDREVTGKYSKYNSSKQRKEMGRVPWNLLRTVEELDGYNVVEILKERCCNCLQFFDSVEELHEHTQVHRQEALAEAACSSKPIKYQCEFCLKSFDLALVYVVHKRIREQRQFYQCRLCDFVIDSESRLKNHMLHNDQHAKFFNLIREDVSDRYYAASLPGARCCGCGQYFDGEDALEEHSRAVHPRDPAKESTKRTHSCRICGKRCYNRSDVLIHQKKNGSTVRYYCKLCDFETANEPRMLKHLYSSIHNEAFPAIEVKNIEIGYKKAGVIRYCCFEGCHLPFHDHQKLFDHVDELHLAQKARNLDAVDQQTGNRLQCDCCHLHFRTLTLLKQHQSGNQRPLKSYVCSVCGLAKPSKAALATHELRHTGARPYPCTVCDKRFSSTTILNSHMKCHAPKQYQCIECGEKFARSENLKRHIRHRHAEATFCCSYCPHKSKTREALNQHERSHTKEKPFECRSEGCQKRYASICDRRRHEMASHTGERPHQCDHCTASFVRKRQLTIHVRKHTGERPFVCLKCGKGFIDSALLKKHTSVTFAVVIGPGSFHHLLQVDLQRTHDKPHLDHVLMPVGVPVLRQLVPPDVKVEKVALIELDVPLEGGVLLAATVRVAELKVCKFVIAVDANLPNGTELVRVLLVVGVLQIRDRIVINVIIEAVAVALKPLRSTGSFVEQSLLNLNFSFEIRWTDCVPEAQVKPSRRQRSLVQKVRHAHVCIVANPVPHQERQRSNVLQLQQNLVEPFLAVQQLHERAQLLLPTLPNLNPQPPLEAQLVHDMFRANPGQPTPVDVPQRKGSLNRSRYPQNRLRPTHLNVSRFSPMAIDRRRSRRCHNQPGTPRTNVQTPVTTMKICRICMQGDEDRPLQSIFSQTDGAHLAETVAASCSLELATEDDGLPGQICAPCVRDVQQVATFRERARESDRKLRQVGASGGGDFEVVVVKTESMGEDDDDREGFNLGQSESDSEDDRPLKRRRRVKASSSDDEEFTVIKVTRKSKQVESDSDDELDVKTLSMFEEVALPEGSYVCCSCYKHFDSVAALELHVEVHKRHAVKRSDCIYCEICKRKFKKESALKRHVAKVSALTKLYECVQCNVRFMNAAGRRMHAQRHPQKIEEKMKQEFGEIFCCVQNCSKSFTSEQLLIEHGHEAHRINKQAYELEDSTLKPIECPVCFKKFASEQLLRRHRRRNSQPLNHQCATCGLKFRTKDVLSFHELNHSEKKPFPCDICQKHFSSKNSLKVHQRSHSNDKPFICSTCGARFYQKAQLVTHEYTHQDGPLPFRCETCSKYCKTKNALRNHMRQHTGEKPYPCRHCSISFSNHTNRQRHEMNHTGNKPFACSFCDRKFTINRLKLEHECKHTGVKPFKCSFCEKSFIRKRFQLDHEATHTGEKPYRCEVPSCNRTFSQQAPLRRHMVTHRTEGSAESTAEFFPLNQQTPNVSILPPSSSV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -