Basic Information

Insect: Culex pipiens
Gene Symbol: -
Assembly: GCA_016801865.2
Location: NC:18977966-19005184[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.002 0.063 14.3 1.2 1 23 1222 1245 1222 1246 0.95

2 13 0.005 0.15 13.1 1.1 1 23 1359 1381 1359 1381 0.99

3 13 0.00018 0.0056 17.6 1.5 2 23 1384 1405 1384 1405 0.97

4 13 0.00034 0.01 16.7 1.8 1 23 1411 1433 1411 1433 0.98

5 13 9e-05 0.0027 18.6 4.6 2 23 1440 1461 1439 1462 0.95

6 13 0.92 28 5.9 0.4 5 23 1475 1493 1473 1493 0.95

7 13 0.0015 0.045 14.7 3.2 2 23 1499 1521 1498 1521 0.96

8 13 0.31 9.5 7.4 0.8 3 23 1535 1554 1534 1554 0.96

9 13 0.00058 0.018 16.0 1.5 1 20 1561 1580 1561 1583 0.92

10 13 0.013 0.41 11.7 0.2 1 23 1591 1613 1591 1613 0.98

11 13 0.00041 0.012 16.5 5.7 1 23 1619 1641 1619 1641 0.98

12 13 0.00032 0.0097 16.8 5.1 1 23 1647 1669 1647 1669 0.99

13 13 0.0042 0.13 13.3 5.4 1 23 1675 1697 1675 1698 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.002	0.063	14.3	1.2	1	23	1222	1245	1222	1246	0.95
2	13	0.005	0.15	13.1	1.1	1	23	1359	1381	1359	1381	0.99
3	13	0.00018	0.0056	17.6	1.5	2	23	1384	1405	1384	1405	0.97
4	13	0.00034	0.01	16.7	1.8	1	23	1411	1433	1411	1433	0.98
5	13	9e-05	0.0027	18.6	4.6	2	23	1440	1461	1439	1462	0.95
6	13	0.92	28	5.9	0.4	5	23	1475	1493	1473	1493	0.95
7	13	0.0015	0.045	14.7	3.2	2	23	1499	1521	1498	1521	0.96
8	13	0.31	9.5	7.4	0.8	3	23	1535	1554	1534	1554	0.96
9	13	0.00058	0.018	16.0	1.5	1	20	1561	1580	1561	1583	0.92
10	13	0.013	0.41	11.7	0.2	1	23	1591	1613	1591	1613	0.98
11	13	0.00041	0.012	16.5	5.7	1	23	1619	1641	1619	1641	0.98
12	13	0.00032	0.0097	16.8	5.1	1	23	1647	1669	1647	1669	0.99
13	13	0.0042	0.13	13.3	5.4	1	23	1675	1697	1675	1698	0.96

Sequence Information

Coding Sequence: ATGGGCACCATCGAATGTCCCGTGTGCACCCTGTACCTCCGGGCCGACATGAGCCTGGAGGACCACCTGGAGACGCACCCGAAGGAGAAGGTCATCCAGGCGCTGGTGTCGATGGCGATGAAGCCGAAGGCGGCTGCGCCGCCGCAAGCTCCGGCGCCCCAACCCCAGCAGCTTGAGGTGGTCCGATCGCGGACACCGCCCAACGCACTCATGTACCACCAGCAAACCGGCAGCAATAGTAGCAGTGGGGGTTACGAGCAGtttcagcaacagcagcagcaaccgaTGATGGCCGCCCCGGCGGCGATCACCGTCGTCAAGGCGTCCGACATGGGCGGCTACCCGATCAACAATGTGATGATCGTGAAGAGTTGCAGCACCAAGTTCGTGCAGCAGATTCCGAGTGGGAGTAGCGCGGCGAATGCCGCGTACGCATCCGGTCCGATCGATGGCCGGAGCATCTTCATAGAACCCGATCGCGGAGGAGGACCTCCGAGCGTGCGTCGCCAGTTGGCGCCGGGACCTTCGCTCTACCCGCCGCGTTACACCAACGAGCGCTACTCGGGCCCACCGCCGCCGTACAGTACGGCCATTTCCTCCACGATCTCCAGCGGTTCGCAGTCCTCGATCAGCGGGTACCAGAAAGCGCcagcgccgccgccgccgcaggCGTTCTACCCGAACCCGCCACCTCCCATAGTACAAAGCACGCCCACGATCGCGCATTACTACGCACCGCCCCCTCCGCCACCGCCAGCACCGGCGATGCCGTCGACTTCGCGGAGCAACCTGCAGGCGCAGTACACCGAAAAGGACGACGGCAACTTTGTGGTGACGGAGAACCCGAAGAAGGTGGTCGAGTACACCGAGAACGACGAGGGGGACTTTATGGTGATCGAGAAGATCATCAAGTCGCCGCCGAGGATCGTCCAGATCGTGGATGAGGTCGAGAAGGAGAAGGACGACTGTggggtggaggaggaggaggaggttgaGCAGCGTGAAGACAGTGAGTACGAGATGGAGATCGAGGAGCAGTATCAGGTTGAGGAGGTTCAGAAGGGGAAGGTTGAGGAGGTGGAGGgggaggaggaagaggaggtGGAGCAGCAGATCGGTACGATCCAGATCGTGGAGAATGAGGACGGGACGTTCGACGACAATCAGCAGTACGGGTTGAAGGAGATGCCGAAGCCGATGTTGATCGGAGGGATTGGGGGATCGCCGAAGAAGAGTCACAAGTTTAGCTTTATTGTGGAACCGACGGCGTCGAGTTCGGGGGGAAGTTCTGCCGCGGGGAGTCCGTACACGCCGCGGAAGAAGCCGACCAGTGGGCTGAAGGTGCTGAGCAATGTCAAGGTGACCACGGATCTGTCCCAGGGCATCAAGGACATCATACTGAACTTGAACTGCAAGAACAAGGGCGTGAACGTGGCGGGTGGTTCGAGCGGGACGTCCGAAGCTGCGGGCACGTCCAGCGGTGTTGGGAGTTTGAAGACGTCGCTGATCACGGGCGTCGTGAACAACAACTGTCAGAACGAGCTTATCATCAACAACATGCCTCCAATTGATCTCAACGATGTGAACGACATTGAAATTATCAACGACGACGAGGAGGAGCTGCGGCCGGGCGAGGACGAAGAGTGCTACATCGGTTCGATGGAGGTCAAAGCGGCCGAAGTGGCCGCACCAACAACGCCGACTCCGTCGGTCATCACCAGTGTAATCCGGATGACCCCACACCCATCTCCAGTTGTCGCACCGCCCTCTCCACCACCCCTACCCGCAAAGCTCGAAACGATCGACCCCGAACCGGAAGATCCGCCAAAACCATCAACCAGCGAGGTGACGATCACGAAGCCAACGCCACGCAAACCAACCCCACAACACCAAACCCCCTCAACCTCAACCGGTTCCCTATTCCACAAACCACCGAAGAAGCTGACCGTCAAGCTCAAGACCCCGCTCCCGCCCGCCCCACCACCAACTCCTCCCCTCATCCCCCAACTCAAGCAGGAAGATCACCCGATGGACCTCGAGCAACCATCGACCTCCGAAGACTGCAAACCACCGCACGCGTACTTTGTCCCCGTTGAACCAACCCCGCCCGAGACCAAGTTCTGCCCGGTCGACGAACGGATctcaccgccaccaccaccccccACCACCCTCACCCTGACCGAGTGCTCCTCCACGGAGACGATCGCCGTCACCACGACCACCACCAAGATCGAGGACGCGATGCATGCGATCTCCAGCGAGACGATCGTGTACACGCAGAGTTCGTCGCCGGAGGCGACCGCCGAGCATCATCAAGCCAGCAGTCCGGGACCTTCCGGGGTCGTCGAAACCACCACGACCTCGGTCGAGTACTACAACATTACGATCATTGACGATGAGGCCGCGGCCGCGGCCGCTCAGTCTTCTAAGCTGGAGCCGGAACTTCCCGAGGAGGGCGTTGTGAAACCGGAGCTCGAGCAGGATCAAAAGTACGAGTACGAGCCCGAGCGGGAGCCGGACTCTCCCGGTTCGAGCGGGTCCGACGAGCAGCAGGAAACGAAGAGTTGCATCAAGGTTGAGAAGATGGAGGTGATGGAGAGTTGCGCGATCGCGCCTCCCGTTGACGAGAGTGAGAAAAAGATTTTGGTGACGAAGGTGGAGCCGGGAAGCGGACCGGACGACCACAAGGACTTCCTCGAGGCTGGACCATCGAGGACGGTGGCGACTACGGTGACGACGGAGGGTGAGGGCAGCAGTAGTAGCAGTAGCAGTGgtggtagcagcagcagcagcagttccgcTGTGGCTTCGTCGTCGCAGGCCGTCGTGGTGAGTTCGGCTGGGCCAACATTCCTGGAGTATAGTGCGGAGTACGATGACTACGTGCCGGTCACCAGTTACGGGATGCCGCAGGAGCAGATTCCGCTGTCGTGGGTGCAGAAGTTTAGTCCGCAGTACACGCCCTTTGACGATCAGAACTCGTACATGGACCTCGATCAGACGGACAGTAAAACCAACTCGAACAGCGTGGGAGGAAATAGCAGCGCCACGAGTAGTGGTGGAAGTGGCAGCAGGATTGAAACCAGCATGGACCGGGCTCCGTCGGCGGAAAGCTTGAATATCCGAACCGACGAGAAGATGCCCGCCAAGGGGGAGATCTCCGAGCAGGAGAGTAACGGGGATATGGAGTTGTCGTGGAATCGGTTATACCCGGTACACGAAAACATCCCAATCTACCCGAGCTCGTACGACCTGTCGACGGCGCAAGAGTGCTGGAACTTGAGCAACCGTACCAGCACCGTAACCGGCCTGAACCAGGATCACCACCACCAGGGGCTGGGACAGCATGGTCAGCAgcatcaccaccaccatcaccaccagtcgtcttcgtcttcgtcgtcTCACCACCACCGCCAGCAACATCAGCAGCCGCAGCAGCAACACGGTCATCAACACGGGATCAGTTTTCAATTCGCCTCCCACGATCAACCCCGGCACGCCGACGAGGACGACGATGACGGGCTGGTGGACGACAAGTCCAAGATCCACCTGGAGTACGGCGGCGAAGGAGGCGCCGCAGGCGCCAGCGGCAGCGGAACCAACAACTACCTGGGCGCGTCCTCGTCCGCCACGGACCACAAGCTGGTGGCCAAGGTGCGCACGTACCGCTGCACCGAGTGTCCCAAGTCGTTTGCGCTGCTGAAGCAGCGACGCGCGCACATGCAGGCGGAACACCACGAGGTCGTGGTCGATAGTAAGTTGAACGTGCTGGCGACGGCGGCGTCGGCGGTCGCTGCGTCTGCGACGGTCACTTCCGGGGCGTTCTTTTCGAACCCAGGCGAGGGGTCGAGTGGGACGGCGGCGGCGAGTGGGGCGACGGCGACGTTGTTGAGCAAGAAGATCAAGATTGAGCCGCAGCCGGTGCTGATGAGTTACAGCTCGCTGAAGCAGGAGCTGGAGCAGAAGCAGGAAGGTGGAGGTGGGGGTTTGGATGTGGCTGGACCGTCGACTTCCGGGATGGGGTCTAGTGGTGGGTTGGGCGCGAGTGGTGGCGAGGTGAGGCGGAAACGAACGTACGTCTGTGGGACGTGCAAGACCGAGTTTGATCGGTTTAAGCTGTTCAACGCGCACTTGATGACGCATCCGGCGGAATGTTACACGTGCGGGCGCAGCTTCAAGCACTGGCCAAACTTTGCGCTGCACATTAAGCGTCACCTGGGAATTAAGGACCACCAGTGTCGGTTGTGCGGGAAGAAGTTTGTCATCAAGCAGAAGCTGATCGAGCACATGCGGGTGCACACGGGGAAGGCGCCGATCAAGTGTCCCGACTGCGATCAGCACTTCCGGCGGTTCTCGAACCTGGCCCAGCACCGCAACCGTCACCACCTGAACAAGGTCCCCTCGAAGAAGGACTTTGTGTGCCACTGCGGCGAAGTGTTCCAATCCAAGGCCAAAATGGAGTGGCACAAGgagatccacgagaacaaaccCAAGAGCTGTCCCTTCTGTCGGGAAAAGTTCATCCACAAAAACAGCCTAACCCGGCACATCCGGCTGTCCCACACGGAAAAGTACGTCAAGCTGGAAACCGCCACCGAGATGTGCACGATCTGCAACCAACCCTACATCAAAACCAGCATGAAACGTCACATGGAAACCCACACGGACGAACGCCTCGCCTACTCCTGCACCATCTGCAACAAGCTGTTCAGCACCAACTGGAACCTGAAGCAGCACAAGTGGACCCACGCCAACCCCACCCTCAAACCGTTCCAGTGCAACCTCTGCTCGTCGGGCTTCGTCCGCGAAGCCGACTACATCACCCACATGAACGCCCACAAGTCGATCCGCCCGTACACCTGCAACCACTGCGGCTGCCAGTTCATCCGCAAGTACAACTGGATCCGGCACACGCGCGAGCACGAAACGGAAAAGAACTACACGTGCGAGATCTGCAACCGCAAGTTCCACCGGAAGTACTACCTGACGGAGCACAAGCGGATACACACCGGCGAGCGGCCCTTCTCGTGCAACATCTGCGGCAAGACGTCCTCCACCAAGACGAACCACAACAAGCACATCAAGATCCACCACGCGCGCGATCCGCTGACGGCCGAGGGTTAA
Protein Sequence: MGTIECPVCTLYLRADMSLEDHLETHPKEKVIQALVSMAMKPKAAAPPQAPAPQPQQLEVVRSRTPPNALMYHQQTGSNSSSGGYEQFQQQQQQPMMAAPAAITVVKASDMGGYPINNVMIVKSCSTKFVQQIPSGSSAANAAYASGPIDGRSIFIEPDRGGGPPSVRRQLAPGPSLYPPRYTNERYSGPPPPYSTAISSTISSGSQSSISGYQKAPAPPPPQAFYPNPPPPIVQSTPTIAHYYAPPPPPPPAPAMPSTSRSNLQAQYTEKDDGNFVVTENPKKVVEYTENDEGDFMVIEKIIKSPPRIVQIVDEVEKEKDDCGVEEEEEVEQREDSEYEMEIEEQYQVEEVQKGKVEEVEGEEEEEVEQQIGTIQIVENEDGTFDDNQQYGLKEMPKPMLIGGIGGSPKKSHKFSFIVEPTASSSGGSSAAGSPYTPRKKPTSGLKVLSNVKVTTDLSQGIKDIILNLNCKNKGVNVAGGSSGTSEAAGTSSGVGSLKTSLITGVVNNNCQNELIINNMPPIDLNDVNDIEIINDDEEELRPGEDEECYIGSMEVKAAEVAAPTTPTPSVITSVIRMTPHPSPVVAPPSPPPLPAKLETIDPEPEDPPKPSTSEVTITKPTPRKPTPQHQTPSTSTGSLFHKPPKKLTVKLKTPLPPAPPPTPPLIPQLKQEDHPMDLEQPSTSEDCKPPHAYFVPVEPTPPETKFCPVDERISPPPPPPTTLTLTECSSTETIAVTTTTTKIEDAMHAISSETIVYTQSSSPEATAEHHQASSPGPSGVVETTTTSVEYYNITIIDDEAAAAAAQSSKLEPELPEEGVVKPELEQDQKYEYEPEREPDSPGSSGSDEQQETKSCIKVEKMEVMESCAIAPPVDESEKKILVTKVEPGSGPDDHKDFLEAGPSRTVATTVTTEGEGSSSSSSSGGSSSSSSSAVASSSQAVVVSSAGPTFLEYSAEYDDYVPVTSYGMPQEQIPLSWVQKFSPQYTPFDDQNSYMDLDQTDSKTNSNSVGGNSSATSSGGSGSRIETSMDRAPSAESLNIRTDEKMPAKGEISEQESNGDMELSWNRLYPVHENIPIYPSSYDLSTAQECWNLSNRTSTVTGLNQDHHHQGLGQHGQQHHHHHHHQSSSSSSSHHHRQQHQQPQQQHGHQHGISFQFASHDQPRHADEDDDDGLVDDKSKIHLEYGGEGGAAGASGSGTNNYLGASSSATDHKLVAKVRTYRCTECPKSFALLKQRRAHMQAEHHEVVVDSKLNVLATAASAVAASATVTSGAFFSNPGEGSSGTAAASGATATLLSKKIKIEPQPVLMSYSSLKQELEQKQEGGGGGLDVAGPSTSGMGSSGGLGASGGEVRRKRTYVCGTCKTEFDRFKLFNAHLMTHPAECYTCGRSFKHWPNFALHIKRHLGIKDHQCRLCGKKFVIKQKLIEHMRVHTGKAPIKCPDCDQHFRRFSNLAQHRNRHHLNKVPSKKDFVCHCGEVFQSKAKMEWHKEIHENKPKSCPFCREKFIHKNSLTRHIRLSHTEKYVKLETATEMCTICNQPYIKTSMKRHMETHTDERLAYSCTICNKLFSTNWNLKQHKWTHANPTLKPFQCNLCSSGFVREADYITHMNAHKSIRPYTCNHCGCQFIRKYNWIRHTREHETEKNYTCEICNRKFHRKYYLTEHKRIHTGERPFSCNICGKTSSTKTNHNKHIKIHHARDPLTAEG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00402044;
90% Identity: iTF_00402044;
80% Identity: -