Cpip005589.1
Basic Information
- Insect
- Culex pipiens
- Gene Symbol
- -
- Assembly
- GCA_016801865.2
- Location
- NC:21227006-21242046[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 18 0.87 27 6.0 5.9 3 23 115 135 113 135 0.96 2 18 5.7e-05 0.0018 19.2 1.2 1 23 143 166 143 166 0.96 3 18 0.065 2 9.5 0.3 2 23 181 202 181 202 0.98 4 18 0.018 0.56 11.3 2.8 1 20 210 229 210 231 0.95 5 18 7.8 2.4e+02 3.0 2.8 1 23 249 271 249 271 0.87 6 18 7.4e-05 0.0023 18.8 0.3 1 23 279 301 279 301 0.98 7 18 0.016 0.49 11.5 1.3 1 23 324 346 324 346 0.98 8 18 9.1 2.8e+02 2.8 0.7 1 8 354 361 354 362 0.92 9 18 0.0005 0.015 16.2 0.6 1 23 445 468 445 468 0.96 10 18 0.022 0.69 11.0 3.2 1 19 472 490 472 491 0.96 11 18 0.37 11 7.2 0.2 2 23 500 521 499 521 0.92 12 18 0.34 10 7.3 0.3 1 13 529 541 529 547 0.86 13 18 0.0044 0.13 13.2 2.6 3 23 566 586 564 586 0.96 14 18 0.07 2.1 9.5 4.2 1 20 594 613 594 615 0.93 15 18 8.8e-06 0.00027 21.7 2.6 1 23 630 652 630 652 0.98 16 18 3.9e-05 0.0012 19.7 3.5 1 23 660 683 660 683 0.97 17 18 0.025 0.77 10.8 3.8 1 23 702 724 702 724 0.98 18 18 2.6e-05 0.0008 20.2 1.8 1 23 732 754 732 754 0.99
Sequence Information
- Coding Sequence
- ATGTCTGAAGCAAATTTAtcacaaataataaaaagagAACCAGTTGAAGAGAGTGCAGAGCATTCAACAACAATCAAGTTGGAAAAAGAATTTCCGGAAAATCCTCAAGTCATTAAACCAACGACAACAACTTCCTTATGCTTCATAAATGCGGACCATACCAAGGTCATTTTAGTCCCAGTAGTGGCCGTTCGTCGCCCCAAACAGGAACCGGAAAAAACCGAAGTCACACAGTTTTCCAGCGAAACGATAGTGAAAGAGGAGCTCATTATCGAGGAAATTAACGAATCAGAAGACGCAACGGATGACTCGAGGATTCCTGATGGAAGCAGAGATCTGTTTTGTCAAGAATGTAACAAAACCTTCAACTGCAGACGATCGTACAACACCCACCGATTGAGACActccaatatcaaaaacattaaatatccGTGCAGTTACTGTGAAAGACCCTTTGCCACGCGGCGCGATCTCACTCGACACGTGCACAGAGTGCATTTTCAGAGCAGCGCGCGGTCAGCCGTGGCCAACCGGATCCGGAAATGTCCGCTATGTCCCACGTTGAGTGACACCAACGACAGCTACCGGAGCCATCTGCTGACTCACGAGCGGCAGCTGCAGAGCATGTTCCGCTGTGAATATTGCAGCATGTGTTTCTTCGAGCAGGATTCACTGCGGCAGCACGTTGCGCATGAAAAGTGCGAAAAGTTGCCCAAATATGACGTTGTCGAGGAAAATGGTATGTTTAAATGCGGCGAGTGTAATCAAGCGTTTTTATTGCGGCGATTATGCCAGCAGCACATCAAGAGACATTCGGCAATTCGAAACAAAACGTTCGAGTGTGATACCTGTGGAAAGCTGTACGGAACCAACTCGGAACTGCTGAGACACGCACGATCCCATGGTGGCGAGCCAACTGCAGGCAAACCGAAGCCAGTCACTCCCAGCGAAGCGGAAACTACCAAACTTTACCGGTGTTCCGAGTGCCCGAAGACGTTTCTGGACTTGGCCGGGTGTGAGCGGCACATCCGGAGGCATGAAAACGTAAGAAATGGAACGTTCCAGTGTGGCGAGTGCGGCAAGCCCGAACCACCGGCCAACTTCCACCATCCGGAAGTTCCCGTTGCACTTCCGGACCAGAAACCGAACATCTCAAACTTCAGCTTCCCAAGCGTGGTAAAGGAGGAACTGATCTTAGAGGATGACACCCCACCTTTTGAACCGGCTAGCGGCGTCCCTGACGGTCCGGAACCGGTTACACCCGGCTTGAACCAGTACGCCTCTGCTGAGGAGGACAGTAACGGTCCCAGCAGCGACATCACTCCCGGAAAATTTGCATGCACAATTTGCCAGCTGTCGTTTCCTAAAAAGCGCGATATACAGCGGCACCAGCGGGAAGAACATAAGCAGCTGTATTTCTGCAACACCTGCGATAAGAGCTTCGACAAGCCGTGCCGTCTGAAGCGGCACGCGCCAAGCTGCAAGGGACGCCCTCTGTACTGTGCCACGTGCGACAAGACGTTCGACGCAGTGAAGGCGTGGTACAAACACCGTGCCAGCCATCGGAACGTAGAGAGTAAAAAGTTCCAGTGTCAGTTGTGTCATAAGCCATTCACTGCCCGATCCGGCTCGCTGCAGCACGAGTGGGAAGTTCACAAGTTTATTCGGCCTGAGCTGGCTGACGAAGTTACGATTTGCAAAATGTGCAACAAACCGTGCTACTCGAAGGATTCTTACGAGCAGCACTTGCAGTCGCACATGCATATCGAAAATAAGACTTTCCAGTGTAAAATTTGTGAGAAAtgCTTTGGATCGGAAAACTGTCTCAAGGGTCACACAACTCGGCAAGAGTGCGAGAAAAAGGTGATGTTGGGCTCGAATGGCGTTTACAATTGTTTCGAGTGCAGCAAAACGTTTTCGCAGCAAATTTTCCTGATCCGACACATGCGTCGGCACGCCCACATTATCAACGGTACCTACAAGTGTGACCTCTGTGGGAAGcactttgcCTCCAACAAAGAACTCCAAACCCACACGAAAAACTTCCACGAATTGCGGAAACCCTCGGCGGTGGATCTTATCCTGACCGACGAGCGGGGCCACTTCAAGTGTCCCAAGTGTGACACGACGTACGAGAATCGTCAGTCCTGCCTGAAGCACATCCTGCGCCACGAGGCGCTCGAAACGGGCAAGTATCGGTGCCAGATTTGTGGGCGCGCTTGCACCACAAAGGTCGTGCTGGAAAAGCACCTCAAAACTCATGAACCCAAGCAGAATGGTCACTCGGAGCATAAGAACCAGAACATGCTTGCGCACAACACCAGCCGGCAATTGAACGGAGAGTCAAGCAGTGCCGCGGAGGGTTTGTCCACCAAAGACACACAGGTGGCCTGA
- Protein Sequence
- MSEANLSQIIKREPVEESAEHSTTIKLEKEFPENPQVIKPTTTTSLCFINADHTKVILVPVVAVRRPKQEPEKTEVTQFSSETIVKEELIIEEINESEDATDDSRIPDGSRDLFCQECNKTFNCRRSYNTHRLRHSNIKNIKYPCSYCERPFATRRDLTRHVHRVHFQSSARSAVANRIRKCPLCPTLSDTNDSYRSHLLTHERQLQSMFRCEYCSMCFFEQDSLRQHVAHEKCEKLPKYDVVEENGMFKCGECNQAFLLRRLCQQHIKRHSAIRNKTFECDTCGKLYGTNSELLRHARSHGGEPTAGKPKPVTPSEAETTKLYRCSECPKTFLDLAGCERHIRRHENVRNGTFQCGECGKPEPPANFHHPEVPVALPDQKPNISNFSFPSVVKEELILEDDTPPFEPASGVPDGPEPVTPGLNQYASAEEDSNGPSSDITPGKFACTICQLSFPKKRDIQRHQREEHKQLYFCNTCDKSFDKPCRLKRHAPSCKGRPLYCATCDKTFDAVKAWYKHRASHRNVESKKFQCQLCHKPFTARSGSLQHEWEVHKFIRPELADEVTICKMCNKPCYSKDSYEQHLQSHMHIENKTFQCKICEKCFGSENCLKGHTTRQECEKKVMLGSNGVYNCFECSKTFSQQIFLIRHMRRHAHIINGTYKCDLCGKHFASNKELQTHTKNFHELRKPSAVDLILTDERGHFKCPKCDTTYENRQSCLKHILRHEALETGKYRCQICGRACTTKVVLEKHLKTHEPKQNGHSEHKNQNMLAHNTSRQLNGESSSAAEGLSTKDTQVA
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -