Basic Information

Insect: Culex pipiens
Gene Symbol: -
Assembly: GCA_016801865.2
Location: NC:181068270-181073083[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 5.7 1.7e+02 3.4 0.1 2 19 364 381 363 384 0.82

2 16 0.00019 0.0057 17.5 0.2 2 23 393 414 393 414 0.98

3 16 0.018 0.55 11.3 0.5 2 23 452 473 451 473 0.97

4 16 0.00049 0.015 16.2 1.7 1 23 478 500 478 500 0.98

5 16 0.2 6.2 8.0 0.1 1 19 520 538 520 540 0.95

6 16 0.013 0.41 11.7 0.8 3 23 555 575 553 575 0.97

7 16 0.00029 0.0088 17.0 0.1 1 23 612 634 612 634 0.97

8 16 0.29 9 7.5 1.1 2 23 779 800 778 800 0.95

9 16 1.7 54 5.1 0.8 1 19 806 826 806 829 0.86

10 16 0.028 0.86 10.7 0.0 2 23 839 860 839 860 0.97

11 16 8.5 2.6e+02 2.9 0.9 1 12 865 876 865 885 0.81

12 16 6e-05 0.0018 19.1 1.7 1 23 969 991 969 991 0.98

13 16 0.00033 0.01 16.8 0.1 1 23 1026 1048 1026 1048 0.97

14 16 4.8e-07 1.5e-05 25.7 0.7 2 23 1054 1075 1053 1075 0.97

15 16 1.9e-05 0.00059 20.7 0.4 1 23 1081 1103 1081 1103 0.98

16 16 8.9e-05 0.0027 18.6 1.1 1 21 1109 1129 1109 1130 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	5.7	1.7e+02	3.4	0.1	2	19	364	381	363	384	0.82
2	16	0.00019	0.0057	17.5	0.2	2	23	393	414	393	414	0.98
3	16	0.018	0.55	11.3	0.5	2	23	452	473	451	473	0.97
4	16	0.00049	0.015	16.2	1.7	1	23	478	500	478	500	0.98
5	16	0.2	6.2	8.0	0.1	1	19	520	538	520	540	0.95
6	16	0.013	0.41	11.7	0.8	3	23	555	575	553	575	0.97
7	16	0.00029	0.0088	17.0	0.1	1	23	612	634	612	634	0.97
8	16	0.29	9	7.5	1.1	2	23	779	800	778	800	0.95
9	16	1.7	54	5.1	0.8	1	19	806	826	806	829	0.86
10	16	0.028	0.86	10.7	0.0	2	23	839	860	839	860	0.97
11	16	8.5	2.6e+02	2.9	0.9	1	12	865	876	865	885	0.81
12	16	6e-05	0.0018	19.1	1.7	1	23	969	991	969	991	0.98
13	16	0.00033	0.01	16.8	0.1	1	23	1026	1048	1026	1048	0.97
14	16	4.8e-07	1.5e-05	25.7	0.7	2	23	1054	1075	1053	1075	0.97
15	16	1.9e-05	0.00059	20.7	0.4	1	23	1081	1103	1081	1103	0.98
16	16	8.9e-05	0.0027	18.6	1.1	1	21	1109	1129	1109	1130	0.94

Sequence Information

Coding Sequence: ATGGCCGGATGCGGCCAGAAATGTTGTGTTTCCGGGTGCGATTCTCGGAAGGACGCCTCCGGCTACTCGTTCCACACCTTTCCGGTGGCCAGTGAGCTGCGGATCGCAAACTTTCGGCGGAAGCTGTGGCACGATGCCGTGTTTGGGAAGGACAGCGCCCGAATCGCCTTGAAAAATACCAAGATTTGCGGGAAGCACTTCGTAACGGgtAAACCAGCCAAGCTCACGGAAACCTCTGAGGTCAACTGGATTCCGACGTTGCACCTGGGCCCGGGCCGGGTGGCACCTCAAGTCAAAACTAGCGGCGGACTGCCGCTGGTCGAGGATGGCGTTCTACCGCCAGAGCAGGTGAACTTCAAGGAGCAAAAGGTTGTCCGACTGGCAGAAAGCAACGAAGCCGATCCTTTTCAAGAGGAGTTTGTAGTCAAAGTGGAAGTACTAGACGTGGAAGTGGCCGATGCTAGTAACGAAGCCGAACCTATCCCGGAGGAGGTCGAAGTCAAAGAGGAAATGTTGGACGTGGAAGTGATCGAAGCAGTGGTTCCAAAGAAACAACGGGTTCTGCGAATAGAAACGAGCAACGCTGTTGAGCCCGTTGAAAAAGTCGCACAAGAAATTAAAGAGGAGATTCTGAATGACGAGGAGGAAATTCAATTCAttcgaaaaaaacaaacttgtcaAATTTCATTCAACCGTTGCATGTTTTGTCTAAACGAACTTCCCCCAAAGGAACAGATCCTACCGGATTTCAACAAGGAGAGCACGTTCCGAACCCAGGTGGAATACGTCCTTGCAAAGACGATCGAAGCCCCAAACTATCCTTGCTGCAGTAGCTGCAAACAAATGTTTCAACTGTTTTACAAGTTCAAGAAGTCTTGCCTCGTTGCCCTTGCCAAACCACtggatttgatcaaatctaaaTCGGCAAAGCGTCCAGCAAACCATCCCATTAGTCCAGCGCCAAAAAGAAAGTCAGAAGTGGTAACCATCCACCCCAAGATCGATGAACGGGACCCGAACGTACCAAACGACGTAGAAGATGACCCGGAAGAATCGCCCTCATCCGATGGGTACAAAGAGGAGCGCATGCGTTGCAAGAATTGCGGTACAATGTACGACGACGGGTTCGTACTGGCCAACCACAAGCTCAACTGTCTACCGCCAAAGGATCCACCCCGGTGTAATCTATGTCCGGCGGTGTTCAAAAATAACTGGGATCTGCAGGTGCACCTGAACCGGCATAACGGCCTAACCCCATTCCAGTGCCGCAAAGAGGGCTGCACGAAGGCTTTCGCCGGCCCAATTGTACGCATCATCCACGAGAAAAACTGTCAAAAGGAGTCCAACCAGGTCGTCTGTCCAAGCTGCGGCATGGCGTTCAAGTGCGAGCTGTATCTGCAGCGCCACATGATCACGCACGAGGCACCGAAGTACGAATGCGCCGTTTGCCATCGCAAGTTCGGCGATTTGACCACCTTCCGAGCCCACATGATGCGACACTTTGAACGGAATGAAACCCCGGCGGAGGAACAACACCGTGAAGACGTTCCGTCCGACTTCCGGTGCGATTCCTGCGAGCAAGAATTCGCCACGCCGGAGCTTCTGAACGGTCACAAGGTGTACTGCGGGAAGAACAAAAAATTCCGCAAGTTCCAGCTGCTCTGCCCGCTCTGTCCGGAGTCGTTCCACAAGCAGGAAACGCTCGATCAGCACCTGAGCCGGCACAAGGGCATCAAGTCGATTCCGTGCCGGAAGGAGGGCTGCGACAAGATGTTCTTCGATACGGCTGGGCGAAACGTGCACGAGCTGTATCGCTGTGGGAGGGGCGGGACGCACGTCTGTTCGATTTGCCAGGCGGCCTTCGGAACGCCGGCATCGCTGCGGGTTCACATGAAGGGACACAGTCTGCGGCTAGAAACAAGAACCATGGACCTTCCGCAGGAATCGATTTCCTTGCAACCAATCATCATAAAAGAAGAATGCGACCCCGAGGACTCACTTtccgaggaggaggaggataaTCCGCAGCACCCTTCCGAATCTCCCTGCTGTGTCTTCTGCTTCCGCGTCCAATCCGACGGGCTGCTCTCCGATGGGCCAGCCTTGCGGGAAAAGATCGAATTCGTGCTCGCGGCGCGGTTACGGTCCCTTAAGGTTCCCAGCTGCCGGAACTGCGCGCAGATGTTCGACTTGTTTTACAACTTCAAGAAGAGCTGCCTGCTGGCGCTGTCCAAAAAGGAGGAACTGCAACAGGCACTGGTGCAAAAGAGTGCCGACGGCAGGTATGCGGAAATGGTGAAGGTTCGGAAGGTGCCGAGGGCAAAGAAGATTATCACATGTTCCGTTTGTACGAGGGAATTTACGGACGAGGACGAGCACCGCTATCACATCAATCAGCACTTTGGGGTCAAACCGTTCAAATGTAAGGTCGCAGGATGCAAACAATCGTTCCCAAACCCAAAAGACTGCTTCGTGCACGAAGCAATGTGCTCGGTAGTGCCGCCACCTTCCAGGGAGTGCGAAGTCTGTGCGTTCCGATTCGCAACGGAGGCGGAGCTCGAGGCGCACAAGATCACGCACAGTGAGCCCAACTTCCAGTGTGGCCGATGTGGAGAAGCGTTCTTTTATGCACTTGACTGCGAAAACCACGAGAGAGACTGTCGCATCCAGGCGGCAGATCCCCTACAAAATATCAAGTTGGAAGACTCCCTAGAAGATCTGGATGAAGAGTCATCGAACAATACTTCCGATGGCTCCAGAAACACCGAACACATCCCCGTCGTCGAGAAGTTCGAACAACCACCCGTAGATAGGCTCTGTAAGCGCTGCGGCGAAACGTTCCCGCTTGCCAACCGCACCTTCCACAAGCACCAGAGGAAATGTAGACCCAGCAATCACAAGACCTATCCGTGTACGCTCTGCGAAAAGACGTTCACCAAGAAGATGACGCTCGAAACGCACCTCAACAAGCACGCAGGAGTTCAGTCGTTCAAGTGCCGTAAACCCGGCTGTGACAAAACCTTCTTCGGATATCCGGCGCGGTACTCGCACGAAGAATCCTGCGGCAGCAAGGGCTTCGTGTGTGACATGTGTGGCGAAACGTTAACGTCGCCGGCCTCGCTACGCATCCACCGGGCCAGGCACGACGAGCCGCAGATTCCGTGCGAGCTGTGCGATAAGATGTTCAAGAccaaGTCCGCCCTGCAGAAGCACATGACGACCCACTCGGAGGAGCGCAAATTCGAGTGCGAAACGTGTGGGAAAAGGTTTAAGTCGGCCGAAGCAAATCGGGTTCACCAGCGGATTCACACCCAGGAGAAGCCGTATGCGTGTCCGGAGTGTGACAAGCGGTTCACGTACAACTGTTCGCTGAAGGCGCACCTGGAGAAGAAGGCGTGCTTGGTGCATTGA
Protein Sequence: MAGCGQKCCVSGCDSRKDASGYSFHTFPVASELRIANFRRKLWHDAVFGKDSARIALKNTKICGKHFVTGKPAKLTETSEVNWIPTLHLGPGRVAPQVKTSGGLPLVEDGVLPPEQVNFKEQKVVRLAESNEADPFQEEFVVKVEVLDVEVADASNEAEPIPEEVEVKEEMLDVEVIEAVVPKKQRVLRIETSNAVEPVEKVAQEIKEEILNDEEEIQFIRKKQTCQISFNRCMFCLNELPPKEQILPDFNKESTFRTQVEYVLAKTIEAPNYPCCSSCKQMFQLFYKFKKSCLVALAKPLDLIKSKSAKRPANHPISPAPKRKSEVVTIHPKIDERDPNVPNDVEDDPEESPSSDGYKEERMRCKNCGTMYDDGFVLANHKLNCLPPKDPPRCNLCPAVFKNNWDLQVHLNRHNGLTPFQCRKEGCTKAFAGPIVRIIHEKNCQKESNQVVCPSCGMAFKCELYLQRHMITHEAPKYECAVCHRKFGDLTTFRAHMMRHFERNETPAEEQHREDVPSDFRCDSCEQEFATPELLNGHKVYCGKNKKFRKFQLLCPLCPESFHKQETLDQHLSRHKGIKSIPCRKEGCDKMFFDTAGRNVHELYRCGRGGTHVCSICQAAFGTPASLRVHMKGHSLRLETRTMDLPQESISLQPIIIKEECDPEDSLSEEEEDNPQHPSESPCCVFCFRVQSDGLLSDGPALREKIEFVLAARLRSLKVPSCRNCAQMFDLFYNFKKSCLLALSKKEELQQALVQKSADGRYAEMVKVRKVPRAKKIITCSVCTREFTDEDEHRYHINQHFGVKPFKCKVAGCKQSFPNPKDCFVHEAMCSVVPPPSRECEVCAFRFATEAELEAHKITHSEPNFQCGRCGEAFFYALDCENHERDCRIQAADPLQNIKLEDSLEDLDEESSNNTSDGSRNTEHIPVVEKFEQPPVDRLCKRCGETFPLANRTFHKHQRKCRPSNHKTYPCTLCEKTFTKKMTLETHLNKHAGVQSFKCRKPGCDKTFFGYPARYSHEESCGSKGFVCDMCGETLTSPASLRIHRARHDEPQIPCELCDKMFKTKSALQKHMTTHSEERKFECETCGKRFKSAEANRVHQRIHTQEKPYACPECDKRFTYNCSLKAHLEKKACLVH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00400916;
90% Identity: iTF_00400916;
80% Identity: -