Basic Information

Insect: Culex pipiens
Gene Symbol: -
Assembly: GCA_016801865.2
Location: NC:51625659-51638283[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 22 0.92 28 5.9 7.4 1 23 186 208 186 208 0.97

2 22 0.27 8.4 7.6 1.7 1 23 214 237 214 237 0.96

3 22 0.00035 0.011 16.7 1.1 1 23 243 265 243 265 0.98

4 22 0.00076 0.023 15.6 1.0 1 23 271 293 271 293 0.95

5 22 0.0025 0.078 14.0 0.5 1 23 315 337 315 337 0.98

6 22 6.2e-06 0.00019 22.2 1.3 1 23 343 365 343 365 0.99

7 22 0.0015 0.046 14.7 5.1 1 23 371 394 371 394 0.98

8 22 4.5e-05 0.0014 19.5 1.8 1 23 400 422 400 422 0.99

9 22 0.53 16 6.7 5.8 1 23 583 605 583 605 0.94

10 22 2.2 68 4.7 5.6 1 23 721 743 721 743 0.95

11 22 0.39 12 7.1 6.5 1 23 863 885 863 885 0.98

12 22 1.9 59 4.9 1.1 1 23 891 914 891 914 0.93

13 22 0.014 0.42 11.7 0.3 1 19 919 937 919 937 0.96

14 22 0.0083 0.26 12.4 3.2 1 23 945 967 945 967 0.98

15 22 0.0024 0.073 14.1 0.4 1 23 1401 1423 1401 1423 0.97

16 22 2.4 73 4.6 1.8 1 23 1429 1452 1429 1452 0.94

17 22 5.6e-05 0.0017 19.2 4.9 1 23 1458 1480 1458 1480 0.99

18 22 1.7e-05 0.00053 20.8 0.4 1 23 1486 1509 1486 1509 0.97

19 22 4 1.2e+02 3.9 4.5 2 23 1527 1548 1526 1548 0.95

20 22 0.02 0.63 11.1 1.8 1 23 1554 1576 1554 1576 0.97

21 22 0.0015 0.047 14.7 5.5 1 23 1582 1605 1582 1605 0.96

22 22 0.054 1.7 9.8 2.2 1 23 1611 1633 1611 1633 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	22	0.92	28	5.9	7.4	1	23	186	208	186	208	0.97
2	22	0.27	8.4	7.6	1.7	1	23	214	237	214	237	0.96
3	22	0.00035	0.011	16.7	1.1	1	23	243	265	243	265	0.98
4	22	0.00076	0.023	15.6	1.0	1	23	271	293	271	293	0.95
5	22	0.0025	0.078	14.0	0.5	1	23	315	337	315	337	0.98
6	22	6.2e-06	0.00019	22.2	1.3	1	23	343	365	343	365	0.99
7	22	0.0015	0.046	14.7	5.1	1	23	371	394	371	394	0.98
8	22	4.5e-05	0.0014	19.5	1.8	1	23	400	422	400	422	0.99
9	22	0.53	16	6.7	5.8	1	23	583	605	583	605	0.94
10	22	2.2	68	4.7	5.6	1	23	721	743	721	743	0.95
11	22	0.39	12	7.1	6.5	1	23	863	885	863	885	0.98
12	22	1.9	59	4.9	1.1	1	23	891	914	891	914	0.93
13	22	0.014	0.42	11.7	0.3	1	19	919	937	919	937	0.96
14	22	0.0083	0.26	12.4	3.2	1	23	945	967	945	967	0.98
15	22	0.0024	0.073	14.1	0.4	1	23	1401	1423	1401	1423	0.97
16	22	2.4	73	4.6	1.8	1	23	1429	1452	1429	1452	0.94
17	22	5.6e-05	0.0017	19.2	4.9	1	23	1458	1480	1458	1480	0.99
18	22	1.7e-05	0.00053	20.8	0.4	1	23	1486	1509	1486	1509	0.97
19	22	4	1.2e+02	3.9	4.5	2	23	1527	1548	1526	1548	0.95
20	22	0.02	0.63	11.1	1.8	1	23	1554	1576	1554	1576	0.97
21	22	0.0015	0.047	14.7	5.5	1	23	1582	1605	1582	1605	0.96
22	22	0.054	1.7	9.8	2.2	1	23	1611	1633	1611	1633	0.97

Sequence Information

Coding Sequence: ATGGATAGTTTCGCTGACCTGTGTCGGCTTTGCCGCGCCCACAACGACCGGGCTGAACACTGGCCACATCTATTTCACTGCGAAGCAACCGAACCCGACTATCACTTGCTACAGAAGATTCACTCCTGCACCAACATCCAAATCACAGAGGATGATCGTCTACCGAAACGTATCTGCTGCCAGTGCCGGTTAGCGCTGGACCAGGCGTACACGTTCCGATTGCAGTGCGATGAAGTGAACACCCAATGGTTACTGGAAGCTGAAGTTCTGGAGCAGAGCGAATCGCCGGTGATTAAAGTAGATCTGGACACTGCGCTTCCTTCAGTTGCTTCGGTTTATGTGAAACCGGAACTTGAGGATGACGATTTTGACGACAGTGAACACTTGAGTTTAGCCGAACTGCTGAAAGTTGAGTCGAAGGAGAAATCCGACGGGGAACTGGTGAAAGATGAACCTAGCGGAGACGAACTGGACGACTCGGATGAACCTGAAGAGGTGAAGCCGGTTCGAAGGAAACGAGGCCCAAAATCGTCGGAGCCGAAACAGAAAACACGCTTCCACTGCAGTTTGTGTCCGAGACACTTTGCCCGAAAGTGTCGACTGCGAGAACACGAGCTAAGACACAGCGGGGTCAAGAACTTTGAGTGCGAGACGTGCCATAACAAGTTCTTTGCGGAAACGGATCTCAGAACGCACATTGCACGGCAACACGCCACGGATCTTCCGTTCATTTGTGAAAAGTGTGGCCAGGGCTTCTCGTCCAAGGGACAACGCACCAATCACTACAATACACATCTGGAGTCGAGGGAATTTGCATGTGATGTGTGCTCCAAAAGCTTCAAAACCAAGTACATTCTGAAGGCTCACATGGAGTTTCATCTGCCGAAGGAACTTCGGAAGGAGTGCTACAAGTACAAGAAACCCGTAGCAAACAACAAAACATACGTCTGTCCATACTGCGGCAAGGTTTCCACGTCCAGCGGAGTACACAACAAGCACATCCGGATCCACACGGGCGATCAGCGGTACGAGTGCAACGTCTGCAACAAGAAGTTTACGGCGTCCTTTTCGCTCATCTCTCATATGCGAACGCACACGGACGAGCGGCCGTACCGATGCGAGCACTGCCAGAAGGCTTTCCGGCTGCGAAACCATATGAAAAATCATGTCCGGTCTGCGCACACGAACGAACGGCCCTACCAGTGCAAATACTGCACGCGGACGTTTGTAACGCGGGGGAATATGCGATTGCACGAGCGGATCCACGGGGAACCGGCGAGCGCACCGACGAAGGTGGCCAGCGTGGATCCattttccggaatcggttccagagcgTCCAAAATGGACACTTTTTGGCTGATGGACGCCTACGCTGACCTGTGCCGGTTGTGCCGCGTCCGGAACGAGGAGCAACCCGCCGAAGAGTGGCCACATCTGTTCCACGTCGGCAACGAGCACCTGCTGATGAAAATCCGAGCCTGCACCAACGTGTGCATAATCGAGCGTGACCCGCTGCCAAAACGCGTCTGCTTCAGGTGCCAGGCGGCCCTCGAACTGGCCCACACGTTCCGGCTGCAGTGCGACAAAGCGGACGCGCAATGGCAGCGCCAGCGGGAGTTGGTGGAAAAGGTAGGACAAACGGCGGCGGTACCGGAAACTGTACCGCTTCTCGAGGCGGAAACGGTGCCCGTTCCGGATGCGACAGAGGTGGTGCGGTACTTTTACCGAGGTCCAAACGACAAGCGCTTCGTGTGTCGGTTCTGTCCGAGACACTTTAGCCGGAAGTGTCGGCTGAAAGAGCACGAGGCACAACATACGGAAACTCAACAGGAAGCTACTCCGCAAAAGGAGTCGGAAGAACATAGCGCGGTAGCCGTGAAGCAGGAGCTGGACATTTTGGATGTGTTCGAAAGCGAAGAGTTGCCAACAACGGATATGTCGGCAAAGGAACTTCAATCCGAACCAGTTCTTAGTTCGGTCGACAAATCAATGCTGGACGACAACAATCGATTACGAGAGAACGAAGTTAATGAATCAGTTCCCGTGACAGAAGCAGAGCCGCCAGCTAAATCACCCATAGAAATGGGTGCTAAACCACCCACCGAGGAGGTCAGGTATTTTTACCGAGGTCCCGGCGGTCCCAACACCTGGAACAAACGCTTCCAGTGCCGATTCTGTCCGCGGCACTTTGGCCGCAAGTGTCGCCTGCGAGAGCACGAGGCACAGCACAAGGAAACTCAACAGGAAACACCGCCAATGGGCGTGGGTGTTGCTGACCCGGTAGCTGTGAAGCAGGAGCCGGAAGTGTTCGTAGTTGAAGAACTGCCAACAAGTGATATGTCAATGAAGGATCTTGAATCGGTACCAGTTCTCAATTCTGTAGGCAAATCAATGCTTGAGATGGACGACAACCATCGAGTACGAGAGCACGAAATTACTGAACCAGTTTCCGTGTCAGAAGGTGAGCAAGGTTCAGTGTACGAGCCGCTAACCGAATCAACGCTTCAAATGGCTGTCGAACCACCCACGGGAGAGGTCAGGTTCTTCTACAGAGGTCCGAGTGGACCCAACTCCTGGAACAAACGCTTCCAGTGTCAGTTTTGTCCGCGGCATTTTGGCCGGAAGTGTCGTCTGCGGGAGCACGAGATGCGCCATAGCGGAGTTCAGAGGTTCCCGTGTGCCAGCTGTAGCCGTTCTTTTTACTCCGAGCGGGATCGCATCGTCCACCAGGAGCACATGCACGGAAATTCCCCGTTCGCTTGCAGCAAGTGTGGCATCAAGTTCAAAACGCAAGAGGGACTGGACAAACACGATCACACGAAACCGCGGAATCACAAGTGTGATCTCTGCTTGAAGGCATTCACGACCAAACAAGGGTTGGAGTACCACAAGCAAAGGCACGCGAAGGCGGACTACTCGAAGCTGCGAGGCCAGGACTTGAACCGGATCTGCATGTGTCCGCACTGTGGTCACATTTCGCACTCGCACAACGCGCACGTTTTGCACCTGCGGACGCATACCGGTGGACAAGATAGTGCGACGGAGTCCGAATCTTCGATTACGCCCTGGACACAAGAAGGAATCTTCAGCGCAATCATAACGTCGTCCCACTTCTTGATAGATCCAACACTTTATTGGGTGGAACCATGCCCCACAAGCGGTTCTCCGTGCGTCTTCTCGTGCGCCTGCATGCTCTGCCGCGTTACGAACGCCATCGGGCAGAACCGACACGGGAAGGGTCGCTCGTTGCTGTGGACCCCGCGGATGTTTGACGGAGTTCTCCCCGAAATTAAACCTCCACCAAGCGTCCGCGTCCTGGCACTGCCGGCGAAAGGTGTCGGCTTGGTCCAGCGAGGCCTCACAGCGTCGGCAGACCCGTTGCGGCAAGCCATCGTCCGCCTCTATTCGCACGCCGGTGCAAAGGTGAATCTTCTCCAGTGTTTGCTCGTGGCCGGATCGACCGAGCAGTGTCCAGTTGTCGGTGGAATCGTTTTCCGCCCGGCACAGCCGGCAGCGTCCGCTTCCCGACACTGCAACCGGAAGGTGTCGGCCTGGTCCAGCGATGCTTCACAGCGCTGGCAGATCCGTTGCGGCAAGCCATCATCCGCCCGTATCTGTACACCGAACGCAAATGCAAACAACAACCGTTTTGTTGATTCCAATCATCAAAACAGTCCACAAAACGACTTCCAttccaaatcaaatcaaaacatgGACCTTTTCGTGAACCATTGCCGACTGTGCCGGGCGGAGAACTCTCCGACAGAAAGCTGGCCACTGCTGATTGAATCTGGTGACGAGCACCTGCTGGAGAAGATCCAAGCCTGCACCGGAGTACAGATTCGGGAGGACGATGGCTTACCACGACGAATCTGCCAGCGCTGTGAAGCATCGCTGGACCAGGCCAACAACTTCCGGGTTCAGTGTCAGGAAGCGGACGCTTGGTGGAGGTTTAATTTCGAGGAAAGCGTCGTCAAACCTGATGCGATTACATTGGTCTTTGTAAAACCGGAAGTAGAAGAGGAGCACGGAGAGGAGAACGATAGCAGTGGGCATCCGGTGGAGACGGTTCTCAAGAAGGAACCGATGATGTTTGAAGATTCCGATTACGAACAAGCAAAGGAGGAGCCAAGCTCGGATGAATGGGAGGCCGTCTCGAAGCGGAAGAAGGCAAAACCAAAGAAGAAAAGTGCAAAAGAATTCCGGTGCGATGTTTGCTCTAGGCAGTTAGCCAACAAGCAAAACCTGGAAGAGCACATGAGCCTACACAGCGGAGTCCAGAACTTTGAGTGTTCGGAGTGCGACAGCAAATTCTTCTGTGCAGCTGGTCTTAAACGGCACGTGGACAGGAAACACCCGGATCACCAGCCATTTCAGTGTGACAAATGTGACCGAAAGTATACAAAGAAATCTCATCTCTTGGAGCACCAAAATACACATTCGGATGCGAGACCGTACAGCTGCAAACTCTGTCCCATGGCGTTTAAGACCAAAACCAATCTAAATGGTCACATGCGATGGGTACACCAACCGGAGGAGGTCAGGGAAGAGTTGAAGAGGAAAAGCGAACGGATTTGCGTATGTTCCTACTGCGGCAAGATTTCCAAGTCAGTCACTACTCACAAGAAGCATCTGATAACTCACACAGGAGAGAAGAACTACGAGTGCCAGATCTGCAACAAACGGTTCACGGCGCTGTGGTCCCACCGCAAGCACATGCTTATCCATACGGACGAACGACCGCACCAGTGCGAGTTCTGTCAGAAGGCGTTCCGTGCGAAACATCATCTGACAACGCACATTCGAGGAGTTCATACCAACGAGCGGCCCTACCAGTGCCGGTTCTGTCCGAAGGCGTTCGTAACCAAGCAGAGCATGCAGTTCCACGAGAAGACGCACGGCGAACCAGTGTCTGGACTAAGCGGGTGTTAA
Protein Sequence: MDSFADLCRLCRAHNDRAEHWPHLFHCEATEPDYHLLQKIHSCTNIQITEDDRLPKRICCQCRLALDQAYTFRLQCDEVNTQWLLEAEVLEQSESPVIKVDLDTALPSVASVYVKPELEDDDFDDSEHLSLAELLKVESKEKSDGELVKDEPSGDELDDSDEPEEVKPVRRKRGPKSSEPKQKTRFHCSLCPRHFARKCRLREHELRHSGVKNFECETCHNKFFAETDLRTHIARQHATDLPFICEKCGQGFSSKGQRTNHYNTHLESREFACDVCSKSFKTKYILKAHMEFHLPKELRKECYKYKKPVANNKTYVCPYCGKVSTSSGVHNKHIRIHTGDQRYECNVCNKKFTASFSLISHMRTHTDERPYRCEHCQKAFRLRNHMKNHVRSAHTNERPYQCKYCTRTFVTRGNMRLHERIHGEPASAPTKVASVDPFSGIGSRASKMDTFWLMDAYADLCRLCRVRNEEQPAEEWPHLFHVGNEHLLMKIRACTNVCIIERDPLPKRVCFRCQAALELAHTFRLQCDKADAQWQRQRELVEKVGQTAAVPETVPLLEAETVPVPDATEVVRYFYRGPNDKRFVCRFCPRHFSRKCRLKEHEAQHTETQQEATPQKESEEHSAVAVKQELDILDVFESEELPTTDMSAKELQSEPVLSSVDKSMLDDNNRLRENEVNESVPVTEAEPPAKSPIEMGAKPPTEEVRYFYRGPGGPNTWNKRFQCRFCPRHFGRKCRLREHEAQHKETQQETPPMGVGVADPVAVKQEPEVFVVEELPTSDMSMKDLESVPVLNSVGKSMLEMDDNHRVREHEITEPVSVSEGEQGSVYEPLTESTLQMAVEPPTGEVRFFYRGPSGPNSWNKRFQCQFCPRHFGRKCRLREHEMRHSGVQRFPCASCSRSFYSERDRIVHQEHMHGNSPFACSKCGIKFKTQEGLDKHDHTKPRNHKCDLCLKAFTTKQGLEYHKQRHAKADYSKLRGQDLNRICMCPHCGHISHSHNAHVLHLRTHTGGQDSATESESSITPWTQEGIFSAIITSSHFLIDPTLYWVEPCPTSGSPCVFSCACMLCRVTNAIGQNRHGKGRSLLWTPRMFDGVLPEIKPPPSVRVLALPAKGVGLVQRGLTASADPLRQAIVRLYSHAGAKVNLLQCLLVAGSTEQCPVVGGIVFRPAQPAASASRHCNRKVSAWSSDASQRWQIRCGKPSSARICTPNANANNNRFVDSNHQNSPQNDFHSKSNQNMDLFVNHCRLCRAENSPTESWPLLIESGDEHLLEKIQACTGVQIREDDGLPRRICQRCEASLDQANNFRVQCQEADAWWRFNFEESVVKPDAITLVFVKPEVEEEHGEENDSSGHPVETVLKKEPMMFEDSDYEQAKEEPSSDEWEAVSKRKKAKPKKKSAKEFRCDVCSRQLANKQNLEEHMSLHSGVQNFECSECDSKFFCAAGLKRHVDRKHPDHQPFQCDKCDRKYTKKSHLLEHQNTHSDARPYSCKLCPMAFKTKTNLNGHMRWVHQPEEVREELKRKSERICVCSYCGKISKSVTTHKKHLITHTGEKNYECQICNKRFTALWSHRKHMLIHTDERPHQCEFCQKAFRAKHHLTTHIRGVHTNERPYQCRFCPKAFVTKQSMQFHEKTHGEPVSGLSGC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -