Cpip018403.1
Basic Information
- Insect
- Culex pipiens
- Gene Symbol
- -
- Assembly
- GCA_016801865.2
- Location
- NW:136365-161136[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 23 0.39 12 7.1 2.2 1 23 152 176 152 176 0.90 2 23 0.63 19 6.4 0.3 1 20 193 212 193 214 0.92 3 23 0.12 3.8 8.7 0.3 1 23 224 247 224 247 0.97 4 23 0.0049 0.15 13.1 1.9 1 20 253 272 253 273 0.96 5 23 8e-05 0.0025 18.7 3.2 1 23 281 304 281 304 0.97 6 23 0.0022 0.066 14.2 1.6 1 23 310 332 310 332 0.98 7 23 3.6 1.1e+02 4.0 4.8 1 23 338 360 338 360 0.98 8 23 1e-05 0.00031 21.5 0.8 1 23 366 388 366 388 0.99 9 23 0.0011 0.033 15.2 5.1 1 23 394 416 394 416 0.98 10 23 5.6 1.7e+02 3.5 2.5 2 23 775 796 774 797 0.94 11 23 0.0097 0.3 12.1 0.9 1 21 811 831 811 832 0.93 12 23 1.8 56 5.0 0.4 1 21 839 859 839 864 0.94 13 23 9.7 3e+02 2.7 3.1 2 19 917 934 917 939 0.90 14 23 1.7 52 5.1 2.5 2 22 1036 1056 1035 1058 0.88 15 23 0.42 13 7.0 0.6 1 19 1072 1090 1072 1093 0.89 16 23 0.2 6.2 8.0 0.4 3 23 1149 1171 1147 1171 0.89 17 23 0.021 0.65 11.1 1.4 3 20 1189 1206 1188 1207 0.95 18 23 0.0055 0.17 12.9 0.0 2 23 1219 1240 1219 1240 0.97 19 23 0.079 2.4 9.3 0.1 2 20 1248 1266 1247 1267 0.95 20 23 5.6e-05 0.0017 19.2 3.1 2 21 1276 1295 1275 1297 0.93 21 23 2e-05 0.00062 20.6 1.9 3 23 1305 1325 1303 1325 0.97 22 23 0.00016 0.0048 17.8 0.5 1 23 1360 1382 1360 1382 0.98 23 23 0.00014 0.0042 18.0 0.5 1 23 1388 1410 1388 1410 0.98
Sequence Information
- Coding Sequence
- ATGGAGAACCTCTGCCGAACGTGCATGTCTACTGTGGACGGCACCGACGACAAATGCTCCATCTCCGTGTACAGCGACACGGAAATGAACGACACCGTTGCCGGCCTGCTGAACACTTTCTGCTCGATGGAGATCGCCCCGGACGACCCGCTGCCCAAGCAAATTTGCCCCGGCTGCGTGCACGAGCTGCTCACCGTAATCAACTTCCGGGCTGTGTCGACCGAGGCTAAACGATTTAGATGTCCCCTACCTCCCCCCACCGAAATGGGACCTTATCAATGTAACAGCTGTGAGGACATTTACGAAAATATAGAAGATGTTACGCAGCACATTGAAGAGGTTCATGAAGTTAGTGAGGTTCAACAACCACCGGTTGAACCGGAGATTGAGGAAGAACCGCTGGTTGAGGAAGTCCCAGCGAAGAAGATAAAGCTAGAGGAAAATTCTGAACGTTACTGCTGCGTAACGCACTGCCATGAGGTCTTCAGCGGCGAGCAGGAGTTGATTGCTCATGCCCAGGAAAAGcacgaaatcaaaataaatcacAACCGAGCCAAGACGGAACCGGACAAACCATTCACCTGCATCGTCTGCTTCCGGTCGTTTGGATCGGTCAAGAACTTGAAAGTGCACCAATTCGTCCGCGCCAACCACAACCAGGGAAAACATTTCAGCTGTGGCCACTGCCCGTTCCGAGCGGTTAGTGCCGCCCTCTTAACCGTCCACGAGCGGTCCAAACACAGCGGAGAACGACCCTTCGAGTGTCCCCACTGCGAGAAGCGGTTCTTCAGCGAACTCCACCTCAAGAACCATCTTGTTTGCCATTCCACAGCGCGGCCCTTTCCCTGCACCTCGTGCGACCGAAGTTTCAGCCGCAAACGCAACATGGAAGAGCACATCCGGTCCTGCCACTCGGAGGACAAACCCTTCCACTGTGACCAATGTCCGGCCCGCTTCAAAGTGCCCCAGCATCTTCGAATCCACGCCCGCATCCACTCGGGAGAAAAGCCTTACCAGTGCCAGTTCTGTACCAACAGTTACTACCACATATCGGACAAAAAGCGCCACGAAATGTCCCACACGGGAGTGCGTCCCTATCGGTGTGAAACGTGCGGAGCCGCCTTCACCCGGAAGCGCACGTTGACCATTCACGAGCGGACGCACACCGGCCACAGGCCATTCAAGTGCGAGCTTTGCTCGAAAGGATTCTGCCAGATGTCGACGTACAAGAAGCACATGGAGCGGCACGAAGGAATGGAGGCGGCGGGGATGGCGGACCTGGTGGAGATTTGCGACGACGGGTCGGCGGAGTCGGATGAGGGGGAGGTGGTGATGGAGGAAGAGGGATTCGCGCCGTCGCGCAAACGCCGCCGCACAGTGCTCGCACTGGTGCGGCTTGACGCCGGTGTGAATGGACCGCTCGTGGCGAGCCCGATCCGTGGCGTGGGCAAACCGGCGCTCACACGGCGGATGCCGACAGCCGAACGGTTTCTCTCCGGTGTGCATCCGGACGTGCAGATCCAGGGCCTCTTTGGTGCGGAGCTTCTTCGGACAGTGCTGACACTCCCAGGGGAAGTTGGCACCGTGGACGTTCCGATGGTGGCGCTTCATGAGGGCGGCGTCGCGGAACACGAACTGACAGTCGGGCTCCGAGCAGGGAATGGCTTCGAAGGGGGTGTGGATTTTGCGGTGGTGCTTCAGGACGGACAGTTTGTGGAAGGCTTTGCCGCACGTTTCGCACACGTGGACGGGCGGTGCCAGGCTGTGGGCGCGTTCCTGGTGGTCGCGGAGTCGGTGGAGCTTGTAGAACTTGGCATCACAGAGCGGGCAGGGGTACTCAGAGCGTTGCTGTTTGTACGTTTGGTGCTGTTGGAGTTTGGGTTCACTTTCGAAGGATCGTTGACAGCGATGGACCAGCTGTGCCGCATCTGTATGGGCACCTTCGAGGGAGACGATCCGGAAGCGAGGACCTCCCTGTACAGCGAGCTTGCCAACGGCAACGAGGTCGTCGCCAACATGATCATCGACTGCGGGGACATTGTGGTCTGTCACGACGACCAACTGCCGGAGTTTGTTTGTGGCGGGTGTTTGGTCCGGTTGAAGGACGCGTTCGCGCTGCGGAAGCTGATCCGGGCATCGGACGGTGCGCTGCGGGAGATGGCCGCGAATAAGACTCAGAATTTAGTTATGGAGGAGGATGTTGGGGGAGAGCAACAAGTGGTGCTGAAGGTTCCTGCCAAAGTGGTCAACTATCCGAGCGAGGATCAAATTGAGAGTGTTCAGGAAGTTGATTGTTACAAGATAATAAGGTTGAAGGGAATCCGATGCTGTGGATGCAATTCGATGTTTGGTTCGCAGCTGGAGGTGGAACGGCACAGTCGGGAGCACCACGGAAGTGCGGAGGTCAAGCAGGAAGCAGATCGGTTGGTTTTCGAATGTCCAACGTGTCATAAGGAGTTTGAGAACAAACTGAAACTGTTGAATCACGCGAAGAACTTCCAATCGAATGAAGTGTATTATTGTACGGTTTGCGACGTCCTCTTTGACATCCGGTACCGGTTGGAGCAGCATCTGAAGTTAAGCAAAGCTCACAGGAATCCTCAGGAGGAACCGCTCAAGATGAGTCTCGATCGTAGGAGATCTTCTGGGAAGAAGAAAGCGACCAGAGAGTTGAAATATCCCGAACAGGACTTCATCCTAGCAATTGAAGAAACTCAAGAGTATCAGTTGATTCACATTGGAGGAGAACGGTGCTGTGGCTGTGAGCGGATCTTTCAAACCTATCAGGAATTGCAGGAGCATTGCAACGAAGCTCACGTCCGGTCACCGGAAAATTCTCTTTGCGAGTGTGGTTTATGCTTTGAAAAGTTTGACCAGATTCAAACATACAATAGACACACCACGGCAAGAAATTTGAAGGAACTCTACTACTGCAAGTTTTGCAAGATCGTAATTGACGTCAAATTTCGCTTCGATCAGCATCTCAAATCAAGCCTGGCTCATCAAGCCGCTCGCGAACAAGCAGGAATCGATCCAAGTCCTCCGTTGGAAGAATTCTCCCGCGTCCTTGAAGCCGGTATCGAAGTTCTCCAAATCGATGGCGTTCGTTGCTGCGGCTGCGACTTCACCTGTGCCAATCGGAATGAACTCGAAGATCACTCGGAAGAAACGCACGGCTTCCAGCGGGTCATCACCGAATCAGAGCCGACCCCTTACGAGTGCGACATCTGCTTCCAACACTTCCCAACCCCACAAACGCTCAAATTCCACACAAATGCCGCCCTCCAAAGCAGCGTCTTCAAGTGCACCCAGTGCGACGTCCAGTCCGAGATCAAACAGCGTCTTCTCCAGCATCTCGCCAGCGGCGTCCACGAGCAAATCCCAAAAAAAGAATCGACCTCCAAACACGCAACCCACAAACTCACACCCCAGCAACACCTGTGCTGCTTCGTGCGCTGTCCAGCCTCCTTCACCTCCCCAACCGAGCTGCTCTCACACGTGGAGTCCGACCACGCCGCGAAACGACGCGAAAATGCCGAAGAGCGCGAACTGGACGGCCCCATCTGCTACGTGTGCCACAAGAGCTTCCGGACGGAGCGCGCCCTGCACGTCCATCAGTTTCCGAAGAATCGCCGCGCGAACTCGCGACCGAACGTGTGCGGTGAGTGTGGAGCGGCGTTCCAGACGGCGTCCGGACTGATCCAGCACGCGAAGAGTCACGCCGCCGAGCGGTGGGAGTGGCAGTGTGACGTGTGCGATCGGAGGTGTCCGGACGAGGGCGCGCTCCGCGTTCACCGCGTTTGCCACGAGGAGGAGCGCGCGTGGGAGTGCGACGAGTGCGGGAAAAAGTTTCGGCGGAAGGGGAATTTGAAGGTCCACAAGCGCTGCCACCGGGAGGTCAGCATCTGGGACTGTCCGCACTGCGAGACCAGCTTCAAAACCAAGCAAAGCCTTACGCTGCACATTCGTAGCCACACCGGCGAAAAGCCTTTCCAGTGTCGGTTCTGCGAGAATCGGTACTCGCATACGACGGACCGGCAGCGCCACGAGATGGCCACCCACACGAAGGAACGGCCGCACCGGTGCGATCTGTGTCCGGCTGCGTTCGTGCGCAAACGGCAGCTGACGATCCACGTGCGGATTCACACCGGCGAGAGGCCGTTCGTGTGCCAGGTTTGTGGCCGAGGGTTCATTCAGGTGAATTATCTGAAGAAGCACTTGACGACCCATGAAAAGGCGGGGAAGGGATTGGTGGAGACGGAGTACATGATCGAAATGCTGCAGGACGATGAGGAAGAGGAACTTTCGGAGACTGAGCAGAAGCGCTACTACGAGTTGGAGATTGAACAGATGGTTGACGAGGCAGAAGAGGACGACGATGACGAATAA
- Protein Sequence
- MENLCRTCMSTVDGTDDKCSISVYSDTEMNDTVAGLLNTFCSMEIAPDDPLPKQICPGCVHELLTVINFRAVSTEAKRFRCPLPPPTEMGPYQCNSCEDIYENIEDVTQHIEEVHEVSEVQQPPVEPEIEEEPLVEEVPAKKIKLEENSERYCCVTHCHEVFSGEQELIAHAQEKHEIKINHNRAKTEPDKPFTCIVCFRSFGSVKNLKVHQFVRANHNQGKHFSCGHCPFRAVSAALLTVHERSKHSGERPFECPHCEKRFFSELHLKNHLVCHSTARPFPCTSCDRSFSRKRNMEEHIRSCHSEDKPFHCDQCPARFKVPQHLRIHARIHSGEKPYQCQFCTNSYYHISDKKRHEMSHTGVRPYRCETCGAAFTRKRTLTIHERTHTGHRPFKCELCSKGFCQMSTYKKHMERHEGMEAAGMADLVEICDDGSAESDEGEVVMEEEGFAPSRKRRRTVLALVRLDAGVNGPLVASPIRGVGKPALTRRMPTAERFLSGVHPDVQIQGLFGAELLRTVLTLPGEVGTVDVPMVALHEGGVAEHELTVGLRAGNGFEGGVDFAVVLQDGQFVEGFAARFAHVDGRCQAVGAFLVVAESVELVELGITERAGVLRALLFVRLVLLEFGFTFEGSLTAMDQLCRICMGTFEGDDPEARTSLYSELANGNEVVANMIIDCGDIVVCHDDQLPEFVCGGCLVRLKDAFALRKLIRASDGALREMAANKTQNLVMEEDVGGEQQVVLKVPAKVVNYPSEDQIESVQEVDCYKIIRLKGIRCCGCNSMFGSQLEVERHSREHHGSAEVKQEADRLVFECPTCHKEFENKLKLLNHAKNFQSNEVYYCTVCDVLFDIRYRLEQHLKLSKAHRNPQEEPLKMSLDRRRSSGKKKATRELKYPEQDFILAIEETQEYQLIHIGGERCCGCERIFQTYQELQEHCNEAHVRSPENSLCECGLCFEKFDQIQTYNRHTTARNLKELYYCKFCKIVIDVKFRFDQHLKSSLAHQAAREQAGIDPSPPLEEFSRVLEAGIEVLQIDGVRCCGCDFTCANRNELEDHSEETHGFQRVITESEPTPYECDICFQHFPTPQTLKFHTNAALQSSVFKCTQCDVQSEIKQRLLQHLASGVHEQIPKKESTSKHATHKLTPQQHLCCFVRCPASFTSPTELLSHVESDHAAKRRENAEERELDGPICYVCHKSFRTERALHVHQFPKNRRANSRPNVCGECGAAFQTASGLIQHAKSHAAERWEWQCDVCDRRCPDEGALRVHRVCHEEERAWECDECGKKFRRKGNLKVHKRCHREVSIWDCPHCETSFKTKQSLTLHIRSHTGEKPFQCRFCENRYSHTTDRQRHEMATHTKERPHRCDLCPAAFVRKRQLTIHVRIHTGERPFVCQVCGRGFIQVNYLKKHLTTHEKAGKGLVETEYMIEMLQDDEEEELSETEQKRYYELEIEQMVDEAEEDDDDE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -