Basic Information

Insect: Culex pipiens
Gene Symbol: -
Assembly: GCA_016801865.2
Location: NC:129600970-129615551[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 21 0.001 0.032 15.2 2.3 3 23 271 292 270 292 0.97

2 21 0.5 15 6.7 0.9 2 23 304 325 303 325 0.94

3 21 0.00034 0.01 16.7 1.3 2 23 330 352 330 352 0.96

4 21 0.13 4.1 8.6 1.8 2 23 359 381 358 381 0.95

5 21 0.4 12 7.1 5.6 2 23 387 408 386 408 0.97

6 21 0.049 1.5 9.9 0.1 1 23 464 486 464 486 0.95

7 21 0.00021 0.0066 17.4 0.6 2 23 493 516 492 516 0.92

8 21 0.00068 0.021 15.8 2.6 2 23 781 803 781 803 0.97

9 21 0.22 6.8 7.9 0.8 3 23 816 836 815 836 0.94

10 21 0.00014 0.0042 18.0 0.9 3 23 842 863 840 863 0.96

11 21 0.019 0.59 11.2 0.8 2 23 870 892 869 892 0.96

12 21 9.6e-05 0.003 18.4 2.0 2 23 898 919 897 919 0.97

13 21 0.00061 0.019 15.9 0.2 1 23 977 999 977 999 0.97

14 21 0.007 0.21 12.6 2.4 2 23 1006 1029 1005 1029 0.92

15 21 0.0019 0.058 14.4 1.6 1 23 1422 1445 1422 1445 0.98

16 21 0.0069 0.21 12.6 1.4 2 23 1455 1476 1454 1476 0.97

17 21 0.0013 0.041 14.8 1.7 3 23 1482 1503 1481 1503 0.97

18 21 0.013 0.41 11.7 8.1 1 23 1509 1532 1509 1532 0.97

19 21 0.0075 0.23 12.5 4.0 1 23 1537 1559 1537 1559 0.99

20 21 0.00071 0.022 15.7 0.6 1 23 1617 1639 1617 1639 0.97

21 21 0.00084 0.026 15.5 2.7 1 23 1645 1669 1645 1669 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	21	0.001	0.032	15.2	2.3	3	23	271	292	270	292	0.97
2	21	0.5	15	6.7	0.9	2	23	304	325	303	325	0.94
3	21	0.00034	0.01	16.7	1.3	2	23	330	352	330	352	0.96
4	21	0.13	4.1	8.6	1.8	2	23	359	381	358	381	0.95
5	21	0.4	12	7.1	5.6	2	23	387	408	386	408	0.97
6	21	0.049	1.5	9.9	0.1	1	23	464	486	464	486	0.95
7	21	0.00021	0.0066	17.4	0.6	2	23	493	516	492	516	0.92
8	21	0.00068	0.021	15.8	2.6	2	23	781	803	781	803	0.97
9	21	0.22	6.8	7.9	0.8	3	23	816	836	815	836	0.94
10	21	0.00014	0.0042	18.0	0.9	3	23	842	863	840	863	0.96
11	21	0.019	0.59	11.2	0.8	2	23	870	892	869	892	0.96
12	21	9.6e-05	0.003	18.4	2.0	2	23	898	919	897	919	0.97
13	21	0.00061	0.019	15.9	0.2	1	23	977	999	977	999	0.97
14	21	0.007	0.21	12.6	2.4	2	23	1006	1029	1005	1029	0.92
15	21	0.0019	0.058	14.4	1.6	1	23	1422	1445	1422	1445	0.98
16	21	0.0069	0.21	12.6	1.4	2	23	1455	1476	1454	1476	0.97
17	21	0.0013	0.041	14.8	1.7	3	23	1482	1503	1481	1503	0.97
18	21	0.013	0.41	11.7	8.1	1	23	1509	1532	1509	1532	0.97
19	21	0.0075	0.23	12.5	4.0	1	23	1537	1559	1537	1559	0.99
20	21	0.00071	0.022	15.7	0.6	1	23	1617	1639	1617	1639	0.97
21	21	0.00084	0.026	15.5	2.7	1	23	1645	1669	1645	1669	0.92

Sequence Information

Coding Sequence: ATGGACTTTGCCAAAATCTGCCGCCTGTGCCTGCAGGAACGAGGCCGGATGCGGAACGTGTCGGAGTACCAAAGTGACTTCTTCAAGATCATCTTCAGCAGCATCCTGCAAATCGAGgtCATTCCGGACGACCAGCTGCCGCAAAAGATCTGCTGGCAGTGCATCTCTGCGCTAACGAAGCTCAACAACACGGTTCTGGAGTTTCGGAGCAACGATCTGAAGCTGCGCAACCAGCTGCGTCAGATGGCTCAGGTCAAGGTGGAAATCGCCGAAGACGAGCAGGAAGTGGATCCGATTTCGATCATaAAATGTGAAGCTGTTGAGGTGGCTCCAGATGAAACCACAACACAACAGGATGAGGACAGTGAAGCTACGTTGGACGCCGATGAGCAAGACGATGTAATTAGCCCTGCATATGAAGAGCACGAGGGGTACCAACCAAGTGAATTGGTTGAGGTTGATTTAACGGTGAACGGAGCAGGATCTGTGCAAAACAAAATCCCCGAGATAATAAATCCCAAGGGAAAGCCTGGTCGTCCTCGGGTGCGACCCATAATAGTGCGGCGGAAGGGAGTTTTTGGGCGTCGGCCCATTCATCCCAGAGATCCGAAAGCGCCGCGCAAAGATGAGAAACGCTGCTACATCTGCATGAGTGATATCTTCGAAAGCGCAGAGGCACTATTTTACCACTTGAACTCACATGCCGATCAGCTGCCGTACACGTGCACGATCTGTGTGCGGGAAACTGTCGTTATCAAACAGATCACCACGCTGAACATCCACAAAAGGATGCACCTACTGCCGGTGGCGTGTTCGCACTGCGACAAGCGATTCGTCTCCGATTCCAGCTTGAAGATGCACCTGACAACTCAGCATCAGGAACTCGATGCAACGAGTGCCGCACCCATGCCGTGTCCTACGTGTGGCAAAGAGTTCCTCTCTGAGAAAGCGCTCAAATTCCACATGCACTCCCACAACCAGCAGGGCAGCTGCGAAATCTGCGGAAAAGTGTACTACGCGAAACATAAGCTGAAACGACACATTCAGCGAGTTCACGAAAAGTCTACCAAAGTCGAGTGTCAAATTTGTCACAAAACGTTAAACGGGTTGGATGTACTGCAGAGTCACATGAAACATATGCATTCGGACGAAAAGATGCAGTGCAAGTACTGTCCAAGAACATATACATGCAAGGCAAGCTTGCTGCATCACGAAAAGCGCCACGAAACCCTGCCCGAGGGGAAAGAAATAAGCAAAGACTGGAAGGAGTACTACACGTACGTCGATGACGAAAGCACCAACGGTGTCCGCCGGAAGAAGTGCAACCTGTGCGGCATCGTGGTGCTGGGCATCGGCGCTCATCTAACGCAGGTTCACTTCCCAAAAAAGTTCGCCTGCGACCTGTGTGAGGCCGAGTTTCGCGACAAAAGAGCGCTGGCCGTGCACAAGCTGGAGCACAGCAAGGGCAAGTTCCTCAAGTGTCCCATCTGTGATCGTGAATTCACCGAGCCTCGCTATCTGATGAACCACCTGAAGACAAAGAAGCACCGCGACCATCCGCTGGCGCAGAACACCGAGTGGCTTAACGAAATGACTTCTTCGGTTGTTAAGACGCCCAAAAGAACGCAATTGAAGACCGCAACCAGGCCGCCGCAAGAAGATGAACACCAAGTCGCAGTGGATGGGCTTGAAATGTTTGAGCAAGACTGGAGTGATTCAATCACGATTGAACTGTTCCGGGCGAACGATTTAAAGCTTCGCAATCAGTTGTACGGATTTGTTGAGGTCAAAACGGAGATCATTGAGGAAACGGTGGAACCGGCACCGTTACCAAATCCcaaaaaagaaGATGAACAGGAGGAAAACGGTGAACTGCCGGAGGCAGAGTACTTGGATGAGGATTTACTCGTGGATCCCAGTGAGATCAAAAGTCCAGAATACGAGGACCTTAAAGGCTTCACTAAAAACGAGGATCAAGACGAATCTGATTTGGACATTACAGCTGATTGGAAGGTGCCAACAGACGAGAGTGATTCTCAACTGGAACGTCCCAAGCGAAAGCAGGGTCGACCGCGGGTTAGACCGATGAAACAGCGGCGAAAGGGCGTCTTCGGTCGGCCCCGAACTAACTTTAGAGATCCAAACCGGCCACGTAAAAACGATCACAAGTGCTACATCTGCATGAGTGAATCGCTGGGAAGTTCCGAAGCGCTCTTTGTCCACTTGAGTTCACACACCGACCAGCTGCCGTACACGTGCACCGTGTGCGTGCAGGAAACGGTCGTAATAAATCAAGTCACCACGCTGAACATCCACAAAAGGATGCACCTACTGCCGGAGAAGTGCCCGCACTGCGACAAACGCTTCAGCGGCAAACACAACATCGAACTACACATATTAATGCTGCACCAGGAGCTCGCACCGCAAGACGAAAGCCCCGCACCGTGCCCCACGTGTGGCAAGGTGTTCCTGTCGGAAAAGGCTCTGCGATTCCACATGCACTCGCACAATCAAAGAATTGCGTGCGAAATCTGCGGCAAAATGTACCACTCGAAAACAAAGCTCCGTGTTCACATTCGACGGGTGCACGAAAAAACCGGCAAAGTGGAGTGCCACATTTGTCACAAAATGCTGAATTCGTTGGATGCGGTTCAAAGTCACATCAATATTATGCACACAAATGAGAAGGTTCAGTGCAAGTACTGCCCGAAGACCTACACCTCGAAAACGAGCCTCCGCCTGCACGAAAAGCGCCACGAAACCATCCCGGAGGGTAAGGAAATGTCCAACGACTGGAAGCAGTTCTACACGTTCGTGGAAGGCAACGAGGACCTGAAGCCGAGTGCCCGCATGAAGCGGTGCAACCTGTGCGGCGCCACCGTGCTGCAAATCGGAACCCACCTGGCCAAGCGCCACTTCCCGAAGGAGTTCCGTTGCGCGCAGTGCGAAACAAACTTCAGCGACCGGAAGGCGCTGGAGGTGCACATGCTGGAGCATAGCGTCGGGAAGTTCCTCAAGTGTCCCATCTGCGAGCACGAGTTTACCGAGCGAAAGTATCTGGTGAAGCATCTCAAGACCAAAAAGCACCGCGACCATCCGCTGGCGCAGAACACCGACTGGCTCGACGCCAAGTACCCGTCGACGGTGCCGAAGCGGATCAAGTCGGAGGGTGGCGCGGTGCAGGAGGTGCAGAGCGCGGTGGAAAAACCCATTGCACCCCGATTGCCCCCGACGTCACCCTTTCCAACTGACAGATCACGCCAGTGTGTTTATATTCATCTGTCActcgccatcgtcgtcgtcgagccAACAGAGCAGCAGCACCAGATTTTTCTTCCAACGATGGAGGACGATTCCGCggtggccgccgccgccgccgaggCGCTTCCGGACGTGAAACAGTCGCTGGATTTCGAGAAAATCTGTCGCCTCTGCTGCGAGGAGCGCTTCCGGATGCGGACCATTCTCGCCACCGAGGGGGACTACGCGCTGGGGAAGATTTTCAGCGAGCTGCTCCGGATCGAGgTTTATCCCGACGATGGGCTGCCGCAGAAGGTTTGCAAGGAGTGCGCCAGGAATATCGTCAAGATGTTCGAGGCCGTCGAGTACTATCGGGCGAATGACATGTCCCTGCGGAAGCATCTGGTCGGAACGGTGGAGAtcaaggaggaggaggaggaagtgGACATGGACTCGCCCAACGTTATACAGCAGCTGAAAATTGAAATGCTCAGCGAACCTTCAGCAGCGCCGGTGAAGAGCGAATATCGCGAAAGACAGCAGCGACAGACGCTCGAGCAGGATTATGAGGACGATCCGACCTGGGAGTTTGGGGACAGTTTGTATCCGGGCAACGAGGACGAAGACGATCGGCAATCTTCCtcatcttcgtcgtcgtcgtcttccgaCAGCAGCGATGGCTCGGTCGACGGAGACACGTCCGACTCGGACGCTTCGGAAGAAATCAAGCCCAAGAAGCGAGGTCGTCCACGGGGCAAAACCAATAGAGGACGTCCGCGGGGATCGGGCGGAAAGCGTGGCCGTCGCAAAACCAAAGTGGACAATCCGAGTCGGCCACGTAAAAACGACCACAAGTGCTACATCTGCGGTTCGGAACCGCTCGGCTCGGCAGAAGCCCTGGTGGCTCATCTGAACGAACACACGTCCGAAGTTCCGTACACGTGTCCAATCTGTGTCATGCAAACGATCGTAATTACCAGTGTCAACACGTTGAACATCCACAAACGGATGCACCTGAATCCGTACAAATGTGACCACTGCGATCGTCGTTACAGCGACCGGAACGCGGTCGATTTGCACATGCAAATGCAGCACACGGGCGCCAACGATCCGTGTCCGTCGCCCTGTTCGTACTGCGGCAAGATCTGTCCGACGCGGCTGTCCCTGCGCTATCACGAGCGAAGTCACCAGACGGCCGTGGCCTGCGAAATCTGCGGCCGACTGTTCGCCGAGAAGCACAAACTCAAGCAGCACATCCGCCGGAAGCACGAAAAGATCCGCGAGCACGAGTGCCACCTGTGCCACAAGAACTTCTCCTCGCTGGACTCGGTTCACACCCACATCCGGACGATGCACTCGAACAACGAGTACAAGTGCGAGTACTGCAGTCGAACTTACACGTCCGAGCTGTCCCTGCGCTACCACAAGAAGAAgcacgaaaatgaccaaaactacCAAGCAACCCAAAAGTGGACCCAATACTACACCGTGCTGGAGCCCGAACCCGGCGCCAAGGAGGGCGCCCAGCGCATGAAGCGGTGCAACATTTGCGGGGCCGTCGTGCAGCAAATCGGCACCCACCTCAGCAACATCCACTTCCCCAAGGAGTTCCGCTGCACGCTCTGTGACGCGGTCTTCAAACGCAAAGAAACGTACGAATCGCACGTCATGGAGCACGAGCACGGCAAAGCGTTCAAGTGTCCAATCTGCGGCAAAGAATTCTCCAGCCGCAAGCTACTCATCTGCCACCTCAAGACCAAACAGCACCGGGATCACCCGCTCGCCCAATCCCTCGATTGGCTGTACACCAAGCGGGAACGCGTACCGAAGCATTTACAACAGCAGCAACCGCCGCCAATTCAACCGCTGCCTCAGCACGTCGTCAAACGGGAAACGACCATCGTGACCGGCGTCGAGCAGACCGTCTACACGACGCCAACAACTCCAACCGTGCAAGTGATGGAACGTGGTGGACCAGCTGTGGCGACGGCGGCGGCTCCGTCCCCGATGGACATGTTCAAGGTCGGAGGAAGCGGGGTGCTCGTGTACCCGTCCGTTGTGGTGGAAACCCACACGCCGGACGTGCGCAGTCCGGAAATGGTCGTACCGGTGCCGATGAAGAGCGACAACGGGATGGTGTTGCATTCGTCGGAAATTTCTTCGATTTAA
Protein Sequence: MDFAKICRLCLQERGRMRNVSEYQSDFFKIIFSSILQIEVIPDDQLPQKICWQCISALTKLNNTVLEFRSNDLKLRNQLRQMAQVKVEIAEDEQEVDPISIIKCEAVEVAPDETTTQQDEDSEATLDADEQDDVISPAYEEHEGYQPSELVEVDLTVNGAGSVQNKIPEIINPKGKPGRPRVRPIIVRRKGVFGRRPIHPRDPKAPRKDEKRCYICMSDIFESAEALFYHLNSHADQLPYTCTICVRETVVIKQITTLNIHKRMHLLPVACSHCDKRFVSDSSLKMHLTTQHQELDATSAAPMPCPTCGKEFLSEKALKFHMHSHNQQGSCEICGKVYYAKHKLKRHIQRVHEKSTKVECQICHKTLNGLDVLQSHMKHMHSDEKMQCKYCPRTYTCKASLLHHEKRHETLPEGKEISKDWKEYYTYVDDESTNGVRRKKCNLCGIVVLGIGAHLTQVHFPKKFACDLCEAEFRDKRALAVHKLEHSKGKFLKCPICDREFTEPRYLMNHLKTKKHRDHPLAQNTEWLNEMTSSVVKTPKRTQLKTATRPPQEDEHQVAVDGLEMFEQDWSDSITIELFRANDLKLRNQLYGFVEVKTEIIEETVEPAPLPNPKKEDEQEENGELPEAEYLDEDLLVDPSEIKSPEYEDLKGFTKNEDQDESDLDITADWKVPTDESDSQLERPKRKQGRPRVRPMKQRRKGVFGRPRTNFRDPNRPRKNDHKCYICMSESLGSSEALFVHLSSHTDQLPYTCTVCVQETVVINQVTTLNIHKRMHLLPEKCPHCDKRFSGKHNIELHILMLHQELAPQDESPAPCPTCGKVFLSEKALRFHMHSHNQRIACEICGKMYHSKTKLRVHIRRVHEKTGKVECHICHKMLNSLDAVQSHINIMHTNEKVQCKYCPKTYTSKTSLRLHEKRHETIPEGKEMSNDWKQFYTFVEGNEDLKPSARMKRCNLCGATVLQIGTHLAKRHFPKEFRCAQCETNFSDRKALEVHMLEHSVGKFLKCPICEHEFTERKYLVKHLKTKKHRDHPLAQNTDWLDAKYPSTVPKRIKSEGGAVQEVQSAVEKPIAPRLPPTSPFPTDRSRQCVYIHLSLAIVVVEPTEQQHQIFLPTMEDDSAVAAAAAEALPDVKQSLDFEKICRLCCEERFRMRTILATEGDYALGKIFSELLRIEVYPDDGLPQKVCKECARNIVKMFEAVEYYRANDMSLRKHLVGTVEIKEEEEEVDMDSPNVIQQLKIEMLSEPSAAPVKSEYRERQQRQTLEQDYEDDPTWEFGDSLYPGNEDEDDRQSSSSSSSSSSDSSDGSVDGDTSDSDASEEIKPKKRGRPRGKTNRGRPRGSGGKRGRRKTKVDNPSRPRKNDHKCYICGSEPLGSAEALVAHLNEHTSEVPYTCPICVMQTIVITSVNTLNIHKRMHLNPYKCDHCDRRYSDRNAVDLHMQMQHTGANDPCPSPCSYCGKICPTRLSLRYHERSHQTAVACEICGRLFAEKHKLKQHIRRKHEKIREHECHLCHKNFSSLDSVHTHIRTMHSNNEYKCEYCSRTYTSELSLRYHKKKHENDQNYQATQKWTQYYTVLEPEPGAKEGAQRMKRCNICGAVVQQIGTHLSNIHFPKEFRCTLCDAVFKRKETYESHVMEHEHGKAFKCPICGKEFSSRKLLICHLKTKQHRDHPLAQSLDWLYTKRERVPKHLQQQQPPPIQPLPQHVVKRETTIVTGVEQTVYTTPTTPTVQVMERGGPAVATAAAPSPMDMFKVGGSGVLVYPSVVVETHTPDVRSPEMVVPVPMKSDNGMVLHSSEISSI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -