Basic Information

Insect: Culex pipiens
Gene Symbol: -
Assembly: GCA_016801865.2
Location: NC:48338258-48340562[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.018 0.55 11.3 1.2 2 21 199 218 199 221 0.89

2 14 2.7e-05 0.00082 20.2 1.3 1 22 238 259 238 259 0.96

3 14 0.035 1.1 10.4 3.7 1 21 264 284 264 286 0.93

4 14 0.12 3.7 8.7 0.5 2 20 295 313 294 317 0.89

5 14 0.017 0.54 11.3 0.3 1 22 329 350 329 350 0.95

6 14 0.027 0.82 10.8 2.7 1 23 354 377 354 377 0.97

7 14 0.32 9.7 7.4 1.3 2 23 388 410 387 410 0.92

8 14 0.00041 0.013 16.5 0.5 2 22 428 448 427 448 0.94

9 14 0.0028 0.085 13.9 3.2 1 23 455 477 455 477 0.97

10 14 0.00057 0.017 16.0 2.4 3 23 485 505 483 505 0.97

11 14 9.8e-06 0.0003 21.6 5.2 1 23 513 535 513 535 0.96

12 14 0.0003 0.0092 16.9 1.5 1 23 541 563 541 563 0.98

13 14 2.5e-06 7.8e-05 23.4 0.8 1 23 569 591 569 591 0.97

14 14 3e-05 0.00093 20.0 1.8 1 23 600 623 600 623 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.018	0.55	11.3	1.2	2	21	199	218	199	221	0.89
2	14	2.7e-05	0.00082	20.2	1.3	1	22	238	259	238	259	0.96
3	14	0.035	1.1	10.4	3.7	1	21	264	284	264	286	0.93
4	14	0.12	3.7	8.7	0.5	2	20	295	313	294	317	0.89
5	14	0.017	0.54	11.3	0.3	1	22	329	350	329	350	0.95
6	14	0.027	0.82	10.8	2.7	1	23	354	377	354	377	0.97
7	14	0.32	9.7	7.4	1.3	2	23	388	410	387	410	0.92
8	14	0.00041	0.013	16.5	0.5	2	22	428	448	427	448	0.94
9	14	0.0028	0.085	13.9	3.2	1	23	455	477	455	477	0.97
10	14	0.00057	0.017	16.0	2.4	3	23	485	505	483	505	0.97
11	14	9.8e-06	0.0003	21.6	5.2	1	23	513	535	513	535	0.96
12	14	0.0003	0.0092	16.9	1.5	1	23	541	563	541	563	0.98
13	14	2.5e-06	7.8e-05	23.4	0.8	1	23	569	591	569	591	0.97
14	14	3e-05	0.00093	20.0	1.8	1	23	600	623	600	623	0.98

Sequence Information

Coding Sequence: ATGGACATCCtaatagaaccagactgcttcAAGGTCTGtcgcatttgcatggaaaactgCGAGGAGGACTTTGTGTGCATCTACGACGAGTTCGAGGACAATATCCTGATGGATGTAATAACCGAATGTGCCCGCGTTGAGATAAGAAAAGATGACGCGCTGCCACGGAACGCCTGCCGAAACTGTGCCGAGTATATGATAATCGCTTATCACATCATCCAGAAGTGTCGTGACGCGGACCGGTCGTTACGGTCGATTTTCAAGCACGAGATCGACCTGCGGAGTCGGAAGGACGAGGCGAAGGCGTTCTGCGCGGAGGAACTCCACATCAATCCGGCCGAGTACGAGTTTCTGCTATCCGAGGCGTACAACAACATGATGCTGGAGAACGTGGAGCGGTTGATTGGGGTTGATCAGGTGGTGCAGCAGGAGGAAGCACCGCCGCCGGTTGAGGCGCAACAGTATCAGGAGAATTGCGATATCGGTACAACAGTACCAGGAGAAGTTGAGTATCCGGATTTGGTTGGTGTTCAGGAGAACCAGCCACCGGAGGAGTCGGAACAACACGGCAACGGTGAGTTGCAGGGAACTAGGAAGTGCTGCGGCTGTAAGAAGGAGTTTGCAACCGAGGTAGATCTGCAGAACCACAGTGACCTGATCCACCTGAACGAGTCGATCAACACTCCGGAAACGGCTGGTAAGCTGAAACCGTTCACGTGTACCGTGTGCTACAAGTCCTTCTCGAACCAGCAGTTGCTGAAAGAACATCAACGCAGCGTGATCCGCAAGTTTTTCTGTCGTCAGTGCGGCCGAGGGTTCATGACCCAAACCAACCTGGACAACCATTTGAAGTGCCACGTGAGTTCGTCTCCGGAGATGAAGAAGTGCTGTGGCTGTCGGAAGGACTTTGATAACGAAGCCGACCTGCTGGCACATTCGGCCGCGGTCCACAAACCGGACCGTACCGACAATCCGGACAAGCCGTTCGAGTGCGAGGTGTGCTTCCGTCGGTATCCGACGCGGAAGTCACTGGTGGGGCATCGCAGGATGATCCAGCAGCACCAGTGCGGTTTTTGTGGGGAGATCTTTGCGAAGAAGTTGTTTTTGACGGCGCACGAGCAGACCTGCCACCAGGGTGGGTCGAGCGATGAGGGTAGGAAACGATGCTGTGGATGTCGGTTGGAGTTTAACAGCTCGAAGGAACTGTTGGAGCACGCGATGGCCACGCACAAACCTGCGGCGGAACTGCAGGACGAAGGCGATGACGAGAAGAAACCTGTCGAGTGTGAGATTTGCTTCAAACGATTCAGCTCGAAGCTGAACCTCGCGCAACACCAGAAGAAGGCCAGCCAAGATCGGAAATATACGTGCGATATCTGCGGGCGAACGTTCCACCGGGCTCACGACAAGGCGAATCACGAGACGACCCACTCCAGCGAAATGCCTTACGGTTGCCAGATCTGCTCGCGGCGTTTCAAGAACAAACTCTACCTCAAGAACCACTACAAAATGCACGCCACAAGCGATTCGCGCGAGTTCGTGTGCCACGAGTGCGGCAAGTGCTTCCGAACGAAGGACCTGCTGAAGACCCACTCCGTTACGCACAGCGAGACACGCAAGTACGCCTGTACGATCTGTCCGGCGACGTTCAAGCGACTGCAATGTCTGAAGATCCACACCAAGGTGCACACGCAGGAAAAGGCGTTCGCGTGTTCGCTGTGCGACAAGCGCTACATCCAATCGTCggacctgaagcgacacctgTTGACGCACGATCCGGGCGAGAGTGGGAAGCCCTTTCAGTGCGAGTACTGCTTGAGGCGGTACCCACGGAAGGATTACCTGAAGGTTCACATCCGCAAGCAGCACCTGGAGAAGGCCGACATGATCCTGATCGAAGATATGGCGCTGGAGTTGCAGGGCGACGAGGAGGATTTTCTACCGATTTAG
Protein Sequence: MDILIEPDCFKVCRICMENCEEDFVCIYDEFEDNILMDVITECARVEIRKDDALPRNACRNCAEYMIIAYHIIQKCRDADRSLRSIFKHEIDLRSRKDEAKAFCAEELHINPAEYEFLLSEAYNNMMLENVERLIGVDQVVQQEEAPPPVEAQQYQENCDIGTTVPGEVEYPDLVGVQENQPPEESEQHGNGELQGTRKCCGCKKEFATEVDLQNHSDLIHLNESINTPETAGKLKPFTCTVCYKSFSNQQLLKEHQRSVIRKFFCRQCGRGFMTQTNLDNHLKCHVSSSPEMKKCCGCRKDFDNEADLLAHSAAVHKPDRTDNPDKPFECEVCFRRYPTRKSLVGHRRMIQQHQCGFCGEIFAKKLFLTAHEQTCHQGGSSDEGRKRCCGCRLEFNSSKELLEHAMATHKPAAELQDEGDDEKKPVECEICFKRFSSKLNLAQHQKKASQDRKYTCDICGRTFHRAHDKANHETTHSSEMPYGCQICSRRFKNKLYLKNHYKMHATSDSREFVCHECGKCFRTKDLLKTHSVTHSETRKYACTICPATFKRLQCLKIHTKVHTQEKAFACSLCDKRYIQSSDLKRHLLTHDPGESGKPFQCEYCLRRYPRKDYLKVHIRKQHLEKADMILIEDMALELQGDEEDFLPI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00401956;
90% Identity: iTF_00401956;
80% Identity: -