Basic Information

Insect: Culex pipiens
Gene Symbol: -
Assembly: GCA_016801865.2
Location: NC:180939368-180960305[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 26 0.66 20 6.4 0.2 1 19 19 39 19 42 0.87

2 26 9.2 2.8e+02 2.8 0.5 6 23 54 71 52 71 0.73

3 26 6.1e-05 0.0019 19.1 4.2 1 23 76 98 76 98 0.98

4 26 0.22 6.9 7.9 0.3 1 23 136 158 136 158 0.95

5 26 0.026 0.8 10.8 2.9 2 23 196 217 195 217 0.97

6 26 5.9 1.8e+02 3.4 0.2 1 23 233 255 233 255 0.93

7 26 1.8e-05 0.00055 20.7 1.2 2 23 352 373 351 373 0.97

8 26 0.32 9.9 7.4 0.2 2 23 459 480 458 480 0.97

9 26 5.4 1.7e+02 3.5 0.3 1 20 486 507 486 511 0.83

10 26 0.16 4.9 8.3 1.9 1 23 528 550 528 550 0.97

11 26 0.047 1.4 10.0 0.3 2 23 586 608 585 608 0.96

12 26 0.002 0.062 14.3 0.2 1 23 631 653 631 653 0.96

13 26 0.029 0.9 10.6 0.8 3 23 690 711 689 711 0.94

14 26 0.00018 0.0055 17.6 1.7 1 23 945 967 945 967 0.99

15 26 0.24 7.2 7.8 0.3 1 19 973 993 973 996 0.90

16 26 0.00099 0.03 15.3 0.7 2 23 1003 1025 1003 1025 0.97

17 26 0.003 0.093 13.7 0.4 1 23 1035 1057 1035 1057 0.96

18 26 7.1 2.2e+02 3.1 2.5 1 19 1063 1083 1063 1086 0.83

19 26 0.0087 0.27 12.3 0.5 2 23 1093 1115 1092 1115 0.96

20 26 0.00063 0.019 15.9 4.1 2 23 1131 1152 1130 1152 0.97

21 26 6.3 1.9e+02 3.3 1.3 2 23 1172 1192 1171 1192 0.96

22 26 3.8 1.2e+02 4.0 0.4 1 20 1198 1217 1198 1219 0.85

23 26 0.00078 0.024 15.6 3.3 1 23 1247 1269 1247 1269 0.98

24 26 5.9e-05 0.0018 19.1 1.5 2 23 1274 1297 1273 1297 0.94

25 26 0.0017 0.052 14.5 0.4 2 23 1312 1333 1311 1333 0.97

26 26 0.036 1.1 10.4 0.2 3 20 1341 1360 1340 1362 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	26	0.66	20	6.4	0.2	1	19	19	39	19	42	0.87
2	26	9.2	2.8e+02	2.8	0.5	6	23	54	71	52	71	0.73
3	26	6.1e-05	0.0019	19.1	4.2	1	23	76	98	76	98	0.98
4	26	0.22	6.9	7.9	0.3	1	23	136	158	136	158	0.95
5	26	0.026	0.8	10.8	2.9	2	23	196	217	195	217	0.97
6	26	5.9	1.8e+02	3.4	0.2	1	23	233	255	233	255	0.93
7	26	1.8e-05	0.00055	20.7	1.2	2	23	352	373	351	373	0.97
8	26	0.32	9.9	7.4	0.2	2	23	459	480	458	480	0.97
9	26	5.4	1.7e+02	3.5	0.3	1	20	486	507	486	511	0.83
10	26	0.16	4.9	8.3	1.9	1	23	528	550	528	550	0.97
11	26	0.047	1.4	10.0	0.3	2	23	586	608	585	608	0.96
12	26	0.002	0.062	14.3	0.2	1	23	631	653	631	653	0.96
13	26	0.029	0.9	10.6	0.8	3	23	690	711	689	711	0.94
14	26	0.00018	0.0055	17.6	1.7	1	23	945	967	945	967	0.99
15	26	0.24	7.2	7.8	0.3	1	19	973	993	973	996	0.90
16	26	0.00099	0.03	15.3	0.7	2	23	1003	1025	1003	1025	0.97
17	26	0.003	0.093	13.7	0.4	1	23	1035	1057	1035	1057	0.96
18	26	7.1	2.2e+02	3.1	2.5	1	19	1063	1083	1063	1086	0.83
19	26	0.0087	0.27	12.3	0.5	2	23	1093	1115	1092	1115	0.96
20	26	0.00063	0.019	15.9	4.1	2	23	1131	1152	1130	1152	0.97
21	26	6.3	1.9e+02	3.3	1.3	2	23	1172	1192	1171	1192	0.96
22	26	3.8	1.2e+02	4.0	0.4	1	20	1198	1217	1198	1219	0.85
23	26	0.00078	0.024	15.6	3.3	1	23	1247	1269	1247	1269	0.98
24	26	5.9e-05	0.0018	19.1	1.5	2	23	1274	1297	1273	1297	0.94
25	26	0.0017	0.052	14.5	0.4	2	23	1312	1333	1311	1333	0.97
26	26	0.036	1.1	10.4	0.2	3	20	1341	1360	1340	1362	0.90

Sequence Information

Coding Sequence: ATGGATAAAAAGCCAAAGCGCGAACAGCTCGCGGATGAACCCAACGCAGATTCCTTCCCGTGCTCCTTCGAAGGATGTGGCAAGGTCTTCCCCAGCCTGACCGCCCAGTGCACGCACGAAGCCGTCTGCAGCCGGGCCGGAGCCGCGCCAAGACTTTCGTGCGAAATCTGCGGCTCCCGGACGTACAAACTGAAGCAGCACATGGTTCTGCATCGGCCACCCGAGCACCAGTGTCCGGTGTGCCGGAAGATGTTCCACTATCGGTACAACCTGACCGCACATCTTAGAGTCCACGCGAAAGAGCTGGACCCACTCGGGGAAGGTTCCTACGAGGGCACGCAATTCTTGCTCCGGATGGTGGACGCTGCACCGCGGATTCCAAAAAAGAAACCCGAGCCGCAGAGCTTTTCCTGCACCGTTTGCCCGGCGGTCTTCAAGGCGAGCAAAACGTTGCGATTCCATTTGAACGCTCACGAAGGTTTAACTCCGTTCGCGTGCCGGAACGAGGGCTGCCAGGAGGCCTTTGCCAACCCGCAGCAGCGCTTCCATCACGAGCCGGTGTGCAGGGGTGAAAGCGGCATGAAGCAGTGCCATGAGTGCGACCAGGAGTTTGACATGAAAAGCTTCTCGAAGCACATGCGGAGCGCCCATCAGGTCGTCCAGCGCGATCGGAACGCCGTCATCAAGAGCCGGTGGTACCCGTGCGGACAGTGTCCGGCCGTGCTGAAGAGCGCAAAGACGCTGGCTTGTCACGTTAACCAGCATAAAGGAATCAAACCGTACCCATGTCGCAACGAAGGCTGCCAGGAGCAGTTCGCCTGGGACAACAACCGGAGGCATCACGAGAAGCGCTGCCGCGAGTCGTCCTCCGTCTGTCCCGTTTGTGGCATCCAACTGGCAAATGGATCGGTTCGCCAGCAGCACATGGCCGCGTTCCACAAGGACGACGCGGTTCTGGAAGAGTTGCTGAAGCTGGAAATCCCGCTGGACGAATCTCCTAAAACGGAGCAACGAAAGGTTCCAGACCCTGACCAACTGCCCGACGGACGGATGGAGTGTCCCGAGTGCGGGAAGATTTTTCGCCAGCGGCACGGCTTCGTGTCCCACATGAACAAGCACAAAGGCGTCCGACCGTACGCCTGTGTCAAGTGCGCTCGAGAATTCTTCAGCAAACAGGCCCACGCGTATCACGAGAAGAAGTGCGTAGCTGGGCTGAAGTTACGCCGAGCTCCCGGTTCAAATCCGCTAAAATCCGATGAACGGAAGATTCCCAAAGAAAAGAAGGCACCGACCCCGATGGTCAAGACTCCTGCTCCTCCTCCAAAGCTAATCACGGCACGAAAGCGCCTGAAAAAGATCAAAGCCGTTCCGAAGCAGTGCGAGCTTTGCAACCAGATTTTGCGTTCGGAGCGGGCGTACGAGTACCACATGGAGGTGCACAACGGGGCCGGAATTTACCGCTGCAAGGCCAAAGACTGCGAGGAAACTTTCCAGACCGTGCGCGAGCGGCAGCTGCACGAAGCGGAACGGCACGGAGGGCGGATGCCGGAGGAGCCCAAGCAGCCGAAGGAGCAGAAAACGTACATGTGCGAGATTTGCTCGACCGTTTGTTTGCGCAAGAAAAGCTTCATCAGTCATATGAACGCGCATAATGGCATCAAAAAGCTCGTCTGCCGCAACGAGGGCTGCGCCGAGACCTTCTACAGCCATTCGGCGCGCCAGTCCCACGAGGAACCGTGCCGCGGGGAAGTGATCACCTGTCCGGTGTGCGACATTAAGGTTAAAACGAAAAACATTCTGCGCATTCACCTGCGACGCCAACATCCAGACCAGCTTCCACCCAGCAGGGCACtgcttcaaaaagttaaaaaggaCGCCGAAAAGAAGACCTTCCCGTGTACGCTGTGCTCGCGGGTGTTCCGGACGCCCAAGTCCTTGGGTGAACACGTGAACGACCACACGGGGGCGAAGCCGTTTCAGTGCCGAAACGAGGGCTGTACGGAGGGGTTCGCGAGACGGGTGGCCCGGATCTACCACGAGGAGGGTTGCCGCGGGCTTGTGGCGCCGTGTCCGTTTTGTGACATCGTGCTCAAGAACAGTCGGACGCTGAAGAATCACGTTGCGTCGTGCCATCCGGCGGAGAAGGAGTCGTTTGATAAGGGGATTTTTTCGTACCAGGATCAGCTCGTTCAGCGGAGTGAGCTGGAGAAGATGATGCTGGAACGGGCTGAGCGGGAACAGGCGGAGGAGGTGGACGAAACGCCGAATGATGAGATCAAGTGCGAAGTGGACGACGAAATGCCAGTTGAGTGGCTTGAAGATATCATCGAAGAGGCCGATCTTGGGGCGAAACTGTTGGAGATTAAGGATGAAGTGATTGTGGAATCTGCACAGCTGTGCCAGGCTAGTAGCTTGGACAACCCTGACGGTATTCAAGTTGAATTAGAGAACGTTGAAATAAAAGCTGAAGTCGATGACGAAACCGATTCGCAGACTGACGAGGAAGATGATCTTTTGGTAGACCCGTTCAACGAACCgaaggaaaaaacacaactTCCAGCCGCCAAACTATTTAAATGTCGCAACGACAACGGCTGCCAACAGATCTTCGAAAGTCATCAGTCCCGGACGCACCACGAGCCTCGCTGCCGGGGAGAGACCTTCTGGTGTCCGCGTACGGGCTGCAAGTACGGTCCAACGACCAAGCTAGATATTGAACAACATCTGCTGCAGAAGCATGGCGACGAGAAAGAAAACGAGGAGACGACGAAGGTTAAAGAGGATCCTGGGGAGGAGGAGGATGAGGAGGACGATTCGTCTGGCAAGGGTAAATTCAAGTGCGAAGAGTGTTGGGCAATTTTTAAGCACGCTAGTTCGTTAAAGTATCACTTGAACAGGCACAAAGGTGCAACACCGTTCTCGTGCCAAAACCCCGGCTGTGGCAGGTCCTTCGCCAGCCCCGGCGAACGTCGCATCCACAACTGCCAAGGCCAGGTGACTGCGCGCACATGTCCGATGTGTCCAACCTCGTTTCAGAACCAAAACCGCCTGTGGTACCACATTCGCACGAAGCACGGTGAAAATGTCAACAACGATCAACGCCACGATTGCGCCGTTTGTGGTGCGTCGTATGTGTTGGAAAAATCGTTGCGAATCCACATGCGCAAACACGACGGAACGCTTCCGTACAGGTGTCGCAAGAAAGGGTGCGACAAGGGCTTCCGCAGTAGCGATCGGCGATGCTACCACGAGCTGAGCTGCGGAGAAGCAGGAGTCGAGTGTACCATTTGCAAAGTTCAACTAAGAAATAATAAGACTCTCGCGAACCACATGAAAAAAGTGCACCAGGATGGGTTGGTAGGATCGAAGAGGGATGAGCACGGATCGCTCATGTGCGAGATCTGCAGTAGAACATTCAACCGTAATTGCGATTTAACAAACCATAAGAAGACACACGTAGAGCCGAAAGATGAGTTGGAAGCGAGCACCATCGATGTCGGCAATGGATTGGTAAAGTGTGGCGTCTGTTCAAAATATCTCCAGAAAAAGACCTACCAATACCACCTGAACTCCCATCGAGGGGTGCGGCAGTACCCTTGCTCCAACTGCCCGCAGGGATTCTTCAGCAAGCAGGCCCAATGGTACCACGAAAAGAAATGCCTTGCGGGACAGAAAATGCGCAAAACCCCGCGAGTCTACATCAAAAACGTCGAGACGGAACCAACAGAACCGATCGTTTTCAAGTGTCCGGACTGTCCCTCAACTTTCCCGAATCGATACACTCTGTACCACCACAAGCAGCGTCACCTGGGCCCCATCGTATGCACCGAAGGCTGCAACAAGAGCTTCAGCAGGGTGGATCTCCTGAGGAAACACATGCGAGATTGTCACGGAATCGGCGAAAAAGCACCCCTCAAGATGGAGAAAACGCTCAAATGTGACTTTTGTCCGTTGATGTTTGGCTTCAAGGCGTCGCTGGTGCGGCATATGAAGTTGCACGATGATTCGAGCCGAGCGAGCTGCACTAACCAGGGATGCAACCAAACGTTTGCGAACGAAAAGGCGTTGCAAAAGCATTTGGCGAGCTGTTCCTCTACTGTGTCGATCAACGGTGAACAGTGA
Protein Sequence: MDKKPKREQLADEPNADSFPCSFEGCGKVFPSLTAQCTHEAVCSRAGAAPRLSCEICGSRTYKLKQHMVLHRPPEHQCPVCRKMFHYRYNLTAHLRVHAKELDPLGEGSYEGTQFLLRMVDAAPRIPKKKPEPQSFSCTVCPAVFKASKTLRFHLNAHEGLTPFACRNEGCQEAFANPQQRFHHEPVCRGESGMKQCHECDQEFDMKSFSKHMRSAHQVVQRDRNAVIKSRWYPCGQCPAVLKSAKTLACHVNQHKGIKPYPCRNEGCQEQFAWDNNRRHHEKRCRESSSVCPVCGIQLANGSVRQQHMAAFHKDDAVLEELLKLEIPLDESPKTEQRKVPDPDQLPDGRMECPECGKIFRQRHGFVSHMNKHKGVRPYACVKCAREFFSKQAHAYHEKKCVAGLKLRRAPGSNPLKSDERKIPKEKKAPTPMVKTPAPPPKLITARKRLKKIKAVPKQCELCNQILRSERAYEYHMEVHNGAGIYRCKAKDCEETFQTVRERQLHEAERHGGRMPEEPKQPKEQKTYMCEICSTVCLRKKSFISHMNAHNGIKKLVCRNEGCAETFYSHSARQSHEEPCRGEVITCPVCDIKVKTKNILRIHLRRQHPDQLPPSRALLQKVKKDAEKKTFPCTLCSRVFRTPKSLGEHVNDHTGAKPFQCRNEGCTEGFARRVARIYHEEGCRGLVAPCPFCDIVLKNSRTLKNHVASCHPAEKESFDKGIFSYQDQLVQRSELEKMMLERAEREQAEEVDETPNDEIKCEVDDEMPVEWLEDIIEEADLGAKLLEIKDEVIVESAQLCQASSLDNPDGIQVELENVEIKAEVDDETDSQTDEEDDLLVDPFNEPKEKTQLPAAKLFKCRNDNGCQQIFESHQSRTHHEPRCRGETFWCPRTGCKYGPTTKLDIEQHLLQKHGDEKENEETTKVKEDPGEEEDEEDDSSGKGKFKCEECWAIFKHASSLKYHLNRHKGATPFSCQNPGCGRSFASPGERRIHNCQGQVTARTCPMCPTSFQNQNRLWYHIRTKHGENVNNDQRHDCAVCGASYVLEKSLRIHMRKHDGTLPYRCRKKGCDKGFRSSDRRCYHELSCGEAGVECTICKVQLRNNKTLANHMKKVHQDGLVGSKRDEHGSLMCEICSRTFNRNCDLTNHKKTHVEPKDELEASTIDVGNGLVKCGVCSKYLQKKTYQYHLNSHRGVRQYPCSNCPQGFFSKQAQWYHEKKCLAGQKMRKTPRVYIKNVETEPTEPIVFKCPDCPSTFPNRYTLYHHKQRHLGPIVCTEGCNKSFSRVDLLRKHMRDCHGIGEKAPLKMEKTLKCDFCPLMFGFKASLVRHMKLHDDSSRASCTNQGCNQTFANEKALQKHLASCSSTVSINGEQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00401973;
90% Identity: iTF_00401973;
80% Identity: -