Basic Information

Insect: Culex pipiens
Gene Symbol: -
Assembly: GCA_016801865.2
Location: NC:152849045-152854140[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.062 1.9 9.6 0.7 1 20 245 264 245 266 0.92

2 16 0.0033 0.1 13.6 2.1 1 23 281 303 281 303 0.96

3 16 0.014 0.43 11.6 0.1 1 19 366 384 366 385 0.96

4 16 0.0095 0.29 12.2 0.8 1 23 398 420 398 420 0.98

5 16 3.2 98 4.2 0.4 1 21 426 448 426 449 0.89

6 16 0.0029 0.088 13.8 0.1 3 23 457 477 456 477 0.97

7 16 1.8e-05 0.00056 20.7 1.6 2 23 484 505 484 505 0.97

8 16 7.1e-06 0.00022 22.0 0.6 1 23 511 533 511 533 0.98

9 16 0.075 2.3 9.4 1.9 1 23 539 562 539 562 0.93

10 16 0.0037 0.12 13.4 1.4 1 21 950 970 950 971 0.95

11 16 5.8 1.8e+02 3.4 1.7 1 23 983 1005 983 1005 0.97

12 16 0.039 1.2 10.3 0.3 1 21 1011 1033 1011 1034 0.94

13 16 0.001 0.031 15.2 0.2 1 23 1040 1062 1040 1062 0.98

14 16 9.9e-07 3e-05 24.7 1.1 3 23 1069 1089 1067 1089 0.96

15 16 8.3e-07 2.5e-05 25.0 0.4 1 23 1095 1117 1095 1117 0.98

16 16 0.34 10 7.3 0.6 1 23 1123 1146 1123 1146 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.062	1.9	9.6	0.7	1	20	245	264	245	266	0.92
2	16	0.0033	0.1	13.6	2.1	1	23	281	303	281	303	0.96
3	16	0.014	0.43	11.6	0.1	1	19	366	384	366	385	0.96
4	16	0.0095	0.29	12.2	0.8	1	23	398	420	398	420	0.98
5	16	3.2	98	4.2	0.4	1	21	426	448	426	449	0.89
6	16	0.0029	0.088	13.8	0.1	3	23	457	477	456	477	0.97
7	16	1.8e-05	0.00056	20.7	1.6	2	23	484	505	484	505	0.97
8	16	7.1e-06	0.00022	22.0	0.6	1	23	511	533	511	533	0.98
9	16	0.075	2.3	9.4	1.9	1	23	539	562	539	562	0.93
10	16	0.0037	0.12	13.4	1.4	1	21	950	970	950	971	0.95
11	16	5.8	1.8e+02	3.4	1.7	1	23	983	1005	983	1005	0.97
12	16	0.039	1.2	10.3	0.3	1	21	1011	1033	1011	1034	0.94
13	16	0.001	0.031	15.2	0.2	1	23	1040	1062	1040	1062	0.98
14	16	9.9e-07	3e-05	24.7	1.1	3	23	1069	1089	1067	1089	0.96
15	16	8.3e-07	2.5e-05	25.0	0.4	1	23	1095	1117	1095	1117	0.98
16	16	0.34	10	7.3	0.6	1	23	1123	1146	1123	1146	0.94

Sequence Information

Coding Sequence: ATGTCACATAAAAGCATTTGCCAAATTCCAGACTCCTCACTTCCGGAATCCATCACCGAAACCAACCTCACAGAACCACTTCTGGAAGTTATCAAAGAGGAACCCCAGCTGGACATCCCAGCCACCGAACAGCTGTACGAAGTCTTGCTCCTAGTTGAGGAACCAAAGTCCGAACCAGCCGAACCCATCCCGGAGGTGTCCCTCTTCTGTTCCCTCTGTCTACGCCCGTGCACCTGCGACCAGGTGGTCGAATTCTCCACCGAACCCAGCTGGAACGGCCTGGATGTGGCGAGCGGACGGGACAAGTTGGTGCCACTTTTGGGCGTGGAGATTGAGCTGGAGCAGTGTGCCGTTTGCCGGTCGTGTTGGACATTGGTGGAAATGTTGGCCGATTTTCGGGAGAGTTGTCTGAAGGCGGCTGCTTGGAGGATGCAGTTCAATTTTGGGTTGGACGAGGTTGGGGACGATTGGTTGTCCAAGGAGAACTTGGAGTTGATGGCGAGGACGCAGAAGGTGGTTCAAAGGCATGTGGAACGTATTCAAACGGCTGAAATTGTGACGCGGAACAGTCAAAATTCGGATGCGAATGATTTGCCGGAGGAGAAGCCAATGCTGAAAGATGAAAAGGATTGGGTGCAAGGCGCGAACTATTCAGAATCACCAAAAGAACTGCCAAAAAATGATTCCCCCAGCGAATCCGCCGAAATCGTCGAGAAAATGGAAATATCATCATTTAGCTGCGCAAAATGCCAGCGAAAGTTTGAAACCAAATCGGGCATGGCGATTCACTTCAAGTATTGCATAAATCCAACGCGCAAGAAGCCACTTGTCCCGAAGCTGCACACTTGCTCGATCTGTTCGGCCAATTTCAGATACTGGTCTCAGTTGGAAGAGCATTTTACAAGGCACGCGGGAAGCAAAGAATTCGAGTGCCGCAAGGGAAACTGCAAGAGACGGTTCTTTTCTATGCCTAGTCGaaagaaacacgaaaacaaTTGCAAGGGAATGAACTTGTTGGAGGTAAGTTTTGGTCAAGAATCTTCGGCAACATGCAGCGAGACCATGGAGATGCAGCTTCCAACAGAGATACGGGTTTACCCGTGCAAAAATTGTCCACGGAAATTCGACACCGAAGGAGGATTGAGTAAACATGCTTGGAGGTGCAAAGAACCAGATCAGAACCGCCAGCTCCACACATGCGAGATCTGTTCGATGGAATTTCTCAATGCTAAAAATCTTGATGCGCACATGAATAAGCACAACGGAATCAAACCGTACAAGTGCAAAAACGAAACCTGCGGCATGCACTTTTACGGCAAGCTTGAAATGTACGCGCACGGTAGAGTTTGTGGCAAGGACAAACCCATCTGCCAGCTGTGTGGCCGTCAGCTGTCCTCGGAGGTGACGCTGCGGGCGCACATGGAAACCCACGCGGCAGAGCCCACCGCCGAGTGTGAAACGTGcggcaaaaagtttaaaacgaAAAAGCTTCTCAAGACGCACCAGGCGGTCCACTCGGACGAGCGGAAGTTTTCGTGCGACGAGTGCGGAAAGGCTTACAAAACGCTGTACGCGCTCAAAGTGCACCGGCGGAATCACATGGAGGTGAAGCCGTTCAGTTGTACCGTTTGCGGGAAGGGGTTCGTGTACAAGTGTCTCGTGAAGCCGCATATGGATAAGTATCATGGCGGAGGGGATTtcAAGGGAACACCAATaaccaaaaacttaattttacaatACAGAATGGAGGGCACCGGCAAAAAGAGTCGCAAAAAGGTCGATCCCAAAGTGCTGGAAGCTTGCATGAGCGCGGTTCGTTCCGGGGAAAAATCCTTCTACGCCGCCAGCAAGTCCTTCGGCATTCCCACCTCCACGATCCGCTACCGGATGAGCGATGAGTGGAAGAACCGAGCTCAGAAAGGGTCGGGCACGGTGTTGACGCCGGCCGAGGAGAAACGGATCATTGCGTGGCTGCAGGACAGCGAGACAAAGGGTCTTCCGGTGGGGAAGCAAACTCTTCTTTTCAAGATTAGAGATTTGCTCGTGGAAAACCCGCGACCGACACCGTTCAAGGACAATATTCCGGGTCGAAAGTGGCTCACTGGATTCCTTAGGCGTCATCAAGGAAAAGTAACGCTGCGAACCGCTGAAGCGGTAATTGCGGCCGGACCTTCCAACAGTCACAACCCCGCCGATGAGCTAGAAACTAAGGAAATCAAGCAGGAAAGCTTGGAGGAAGTTTTCGCCGAACCGATAAACATCCGGAAGTGCCAAAAATCGGAGCCACCTTCAACGTTCTGCTCGCTCTGTCTGCGGCAATGCTTGGAGGAGCAGGTCCAGGAATTTTCCACCTACCAGAGTTGGAATGGGGCCAGCTTCGAAGATCGTCGGGGGAAGTTGGAGCAGATGCTGGGAGGCGTGCAGATTGACGGGGACATTTGTCAGACCTGCTGGCGCATGGTCGAGCTGGCCGTGGACTTCCGGCAGAGCTGCTTGAAGATGGTCGAGTTAAAGGAGAGATATCCGGTTGGAGTTGCGAGGAAGGATGAGGACGAGGAGGAATGGTTTGTTGGGGGAACCTTGGAAGGTTTGGGTCGAACGCGGAAGATGGTGCAGGATCATATGCAGCGCGTTGAGTTCGCGGAGGTCAGTTTGAGGAATGAAATCAACATGAAAGTAGAGAAGGGTTCTGACGATGACACGACTTTGCTGGAAGAAGATACGGATTTTTGTGAAGATCACTTCGAAGATGACACTGGAAGCAATCCTGACGAATCAACGGAAAACGTGGAAGAACCTTGCGATGAACCAGACTTAACACTAGCCGAAAGCATCCCAATTCCACTGTTCACATGCACCAGCTGCAACAGATCGTTCGAGAGCAAAGTGTCGCTGCACGTCCATCTGAACTATTGCGACAGTTCGAAAACGGAACCGATCCGCACGTTCAGCTGCACAGTCTGTTCGGCGGATTTCATGTGCCGCGAATCGTTGACCGGTCACCTCAACAAGCACAAAGGAATCAAACCGTTCCAGTGTTCCAAACCCAGCTGCACCAAGACCTTCTACAGTCCGATGACGCTGCGCGTCCACGAGCGAGGTTGCGGCTCGTCCCCGTTCGTTTGTGCGCTGTGCGGAGTGACCACCAAGACCCTTTCGAGCTACAGAGCGCATCAGGAGACACATAACGAGCGTACGCTGGCCTGTCCGGATTGTGATAAGAAGTTCTCGTCGAGGACGTACCTCAAAAAGCACCAGAAGGTGCACACGAACGCACGGAACTACCCGTGTACGGAGTGCGGGAAGACGTTCAAGACCAACTATGCGGCGCGGGTTCATATGAGGATTCACACGCAGGAGAAGCCGTTTAGTTGTGCAATTTGTGGGATGGGATTTGCGTACAAATGCTTGGTGAAGCCGCACATGGAGAAGAACCACGAGGGAGCGATTTAA
Protein Sequence: MSHKSICQIPDSSLPESITETNLTEPLLEVIKEEPQLDIPATEQLYEVLLLVEEPKSEPAEPIPEVSLFCSLCLRPCTCDQVVEFSTEPSWNGLDVASGRDKLVPLLGVEIELEQCAVCRSCWTLVEMLADFRESCLKAAAWRMQFNFGLDEVGDDWLSKENLELMARTQKVVQRHVERIQTAEIVTRNSQNSDANDLPEEKPMLKDEKDWVQGANYSESPKELPKNDSPSESAEIVEKMEISSFSCAKCQRKFETKSGMAIHFKYCINPTRKKPLVPKLHTCSICSANFRYWSQLEEHFTRHAGSKEFECRKGNCKRRFFSMPSRKKHENNCKGMNLLEVSFGQESSATCSETMEMQLPTEIRVYPCKNCPRKFDTEGGLSKHAWRCKEPDQNRQLHTCEICSMEFLNAKNLDAHMNKHNGIKPYKCKNETCGMHFYGKLEMYAHGRVCGKDKPICQLCGRQLSSEVTLRAHMETHAAEPTAECETCGKKFKTKKLLKTHQAVHSDERKFSCDECGKAYKTLYALKVHRRNHMEVKPFSCTVCGKGFVYKCLVKPHMDKYHGGGDFKGTPITKNLILQYRMEGTGKKSRKKVDPKVLEACMSAVRSGEKSFYAASKSFGIPTSTIRYRMSDEWKNRAQKGSGTVLTPAEEKRIIAWLQDSETKGLPVGKQTLLFKIRDLLVENPRPTPFKDNIPGRKWLTGFLRRHQGKVTLRTAEAVIAAGPSNSHNPADELETKEIKQESLEEVFAEPINIRKCQKSEPPSTFCSLCLRQCLEEQVQEFSTYQSWNGASFEDRRGKLEQMLGGVQIDGDICQTCWRMVELAVDFRQSCLKMVELKERYPVGVARKDEDEEEWFVGGTLEGLGRTRKMVQDHMQRVEFAEVSLRNEINMKVEKGSDDDTTLLEEDTDFCEDHFEDDTGSNPDESTENVEEPCDEPDLTLAESIPIPLFTCTSCNRSFESKVSLHVHLNYCDSSKTEPIRTFSCTVCSADFMCRESLTGHLNKHKGIKPFQCSKPSCTKTFYSPMTLRVHERGCGSSPFVCALCGVTTKTLSSYRAHQETHNERTLACPDCDKKFSSRTYLKKHQKVHTNARNYPCTECGKTFKTNYAARVHMRIHTQEKPFSCAICGMGFAYKCLVKPHMEKNHEGAI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -