Basic Information

Insect: Culex pipiens
Gene Symbol: -
Assembly: GCA_016801865.2
Location: NC:88333738-88343269[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.0059 0.18 12.8 1.8 1 23 47 69 47 69 0.97

2 16 0.53 16 6.7 0.4 1 23 75 98 75 98 0.92

3 16 0.042 1.3 10.1 0.2 1 23 101 124 101 124 0.96

4 16 9.4e-05 0.0029 18.5 0.0 3 21 134 152 132 153 0.93

5 16 0.018 0.55 11.3 1.7 1 23 161 183 161 183 0.97

6 16 0.0032 0.098 13.7 1.2 3 23 191 211 189 211 0.96

7 16 4.9e-05 0.0015 19.4 2.2 1 23 217 239 217 239 0.98

8 16 1.1 34 5.7 2.3 1 21 245 265 245 266 0.95

9 16 0.56 17 6.6 0.1 2 23 577 599 576 599 0.95

10 16 0.0051 0.16 13.0 0.6 1 23 622 644 622 644 0.98

11 16 0.0023 0.07 14.1 0.9 2 23 680 702 679 702 0.95

12 16 0.0011 0.035 15.1 0.2 1 21 711 731 711 732 0.92

13 16 4.8e-06 0.00015 22.6 0.5 1 23 740 762 740 762 0.97

14 16 4.1e-05 0.0012 19.6 3.8 1 23 768 790 768 790 0.98

15 16 0.017 0.52 11.4 4.1 1 23 796 818 796 818 0.96

16 16 0.00054 0.017 16.1 2.0 1 23 824 846 824 846 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.0059	0.18	12.8	1.8	1	23	47	69	47	69	0.97
2	16	0.53	16	6.7	0.4	1	23	75	98	75	98	0.92
3	16	0.042	1.3	10.1	0.2	1	23	101	124	101	124	0.96
4	16	9.4e-05	0.0029	18.5	0.0	3	21	134	152	132	153	0.93
5	16	0.018	0.55	11.3	1.7	1	23	161	183	161	183	0.97
6	16	0.0032	0.098	13.7	1.2	3	23	191	211	189	211	0.96
7	16	4.9e-05	0.0015	19.4	2.2	1	23	217	239	217	239	0.98
8	16	1.1	34	5.7	2.3	1	21	245	265	245	266	0.95
9	16	0.56	17	6.6	0.1	2	23	577	599	576	599	0.95
10	16	0.0051	0.16	13.0	0.6	1	23	622	644	622	644	0.98
11	16	0.0023	0.07	14.1	0.9	2	23	680	702	679	702	0.95
12	16	0.0011	0.035	15.1	0.2	1	21	711	731	711	732	0.92
13	16	4.8e-06	0.00015	22.6	0.5	1	23	740	762	740	762	0.97
14	16	4.1e-05	0.0012	19.6	3.8	1	23	768	790	768	790	0.98
15	16	0.017	0.52	11.4	4.1	1	23	796	818	796	818	0.96
16	16	0.00054	0.017	16.1	2.0	1	23	824	846	824	846	0.98

Sequence Information

Coding Sequence: ATGAGTTCCGACGAGGAGCAGCAAGTGGAAGAGGTGTCCCCGTCACGGAAGCGGGCCCGCACGTCCAGAGGGACGGACGATTCGTCGGGGCCGTCCCCGTCGAAGAAGCCGGACGATTCGGAACTGGACGGAATCCATTATGCGTGCAGCGTTTGCGACCAGGTGTTCCTGCACAAGGCCAACTACCTGCGGCACACGCAACGGCACGAACCGCCGGGTGGATTCCTGTGCTCGATCTGCGTCCAGCCGTTCACCACCGACTGGGACCGGAACAAGCACAAGCGGGACGAGCACAGCGTCTTCCGGTGCCGACTGTGCAAGGAGGAGTTCCCGGTGGAGGACGATTACAACGAGCACATTCAGGAGCAGCATGCCGGGCGGGACCGGGAGTACGACATCTGTCCGACCTGCGGGCAGCAGTTCCGGACGGCATCGCAGCTCAAGGTCCACATCGAGTCCAACTGCGGCACGGACAAGAAGCACGAGTGCGAGGAGTGCCACCAGCGCTACTTGACGCTGGCCTCGCTGAACGCGCACATGATCAAGCACGCCGGCATCAAGAGCCACCTGTGCAACTTTTGCGGCGCCAGCTTCCTGAACAAGGGCCAGCTCAAGGTGCACGTCCGGATGCACACGGGCGAGCGGCCGTACAAGTGTAATcAATGCGATAAGGCCTTTGCCCATCGGGAAAGTTTGATCACCCATTCGACGACCCACTCCGGGATTAAGCCGTACTACTGCAGCTACTGCCAGAGTCGGTTCTCGTGCATTGGAAATTTGCTAAAACATCGTCGAGCTCGCGCAGACACGTGTGGATTGCCGCAGTACTGCCAAACTAATAAGATCGCCGCCAGACCGAACATCAAGACAATGCCCAACCTCACCGATCGCCCAGTCTACACCCAGAAGGTTGTACAGCGCTCGAGTCCGGTAAAGTCGCGCAGCAAACCGAAGCCGAGCGAAATAGTCGTCTCCGTCGAGGTGGTTCCGCCGAAGAAGCGCCCCAGCAAACAGGTGGCCCGCCCTGCGTTGCCACCGCCGCCACCCTCGACCGTCCAATCGGACGACGAAGACGACCGTACGAAGGACTTTGAGGACGAATACTACGAGCGAAAGCCGAACGTGGCCAAGCTTAAGGTCGCTCCGGCCGCCGCCGGGTCCAAGTATCGGCGGTTGGTCGATCTGAAGGTCGAACCGGGCGATTCAGACGAGGCTGGCGAGTGTAGCGTCGTGAAGGTCGAGAAGCATGCCGCCAGCAGTGGAGACGATGAGCACGTCGAGTTCTTCGAGGTGAAAATCGAGCAGGAGAACGACGAGCTGATTGAAACCATCGAGGAGGAAACGCTCGAGGAGTACGAGGAGGTCCTGTCGGAGAAGGTGGTCACGCTGGACAGCAAGGGACGCGCCGTCGTGGACAGCGATGACGACTTCAACGACGCCACCAACGAGGACTACCTTGAAGAGGCGACGGACGAATTCCAACCGCCAAAGCAGCAGGATCAGTATCATGATGGCGATGTCGTGATTAAGCGGAAATTTACCACGAAGCCACCGGTGGTGACGCAGCCAAAGCGACGCGGACGGCCCAAGCGACCGCCAGCGCCAAAGTTCCAGAACGTCAACCCGGAGCATGTGATCGTGATCAACTTGGAGGAGAAGCAGAAGGTCATCGACGAGCAGCGGGCCATTTACGACGCAAACATTATCGAGGTCACCGTCGGCTGTCTGCAGTGCGGCATCTGTCCGGCGCAGTACTGTTCACCGTTTCTGGCGGCCCGTCATCTGGAGCGCGACCACGGCATTATGATGCACGAGCTGGGAGAAACGCTCCGCTACGATCGCGTGTTCACGCGCGAGCGCAAATATCAGTGCCGCTTCTGCAACCGTCTGTACGTGAACGAAAAAGCGCTCGAGAAGCACATCCTGCTGCACGGACCAAACGGCACGGCCGTGCACAAGTGCCCAATCTGTACGAGCTGGTTCGAATCGGAGGAAGAAGCGCTCAATCACTCCCGGATCGAGCATCGCGAGAAGCTCGAATGTCCGGTGTGTTTCAAGTTCTTCAGCAATCAAGAACGCATGATCAAACATCGCAAGCAGATCCACGAACAGACCCGCGTCAAGCAGGACCACGTCTGCCCCAAGTGTGGCAAAAACTTTTCCTCCCGCGGGGCCGTGTCCGATCACGAGCGTTCCAACTGTGGCCAGAACCCGATCTACCCGTGCGAAATCTGCGGCAAGCGCTACAACACGGCGTCCTCCCTCAAGAACCACTACAGTCTTCACTCGGACGAACTGCCCTTCTCCTGTCAGTACTGTGGCAAGTGCTACCGCACCCGGGGCCAGGTCAAGGTTCACGAGCGCACCCACACCGGTGAGAAGCCATACGCGTGCGATTTCTGTCCGAAAAGGTTTGGCCATCGCGAGACGCTTCACACCCATCGGTCGCTGCACACCGGCATCAAGCGGTACATGTGCTCCGGCTGTGGAATGCGCTTTACTTGCATCTCGAATCTGCAGGCCCATCGGCGGTCGCACAAAACCACCTGCGGCATGATTCCGACGTACTCGAAGGTGCGCGGACCGGACGGAGTGCACGAGCTGCCCGAGGGGTATGAGTTGCCGTACCCGCTGAATGATCAAGAAACGTAA
Protein Sequence: MSSDEEQQVEEVSPSRKRARTSRGTDDSSGPSPSKKPDDSELDGIHYACSVCDQVFLHKANYLRHTQRHEPPGGFLCSICVQPFTTDWDRNKHKRDEHSVFRCRLCKEEFPVEDDYNEHIQEQHAGRDREYDICPTCGQQFRTASQLKVHIESNCGTDKKHECEECHQRYLTLASLNAHMIKHAGIKSHLCNFCGASFLNKGQLKVHVRMHTGERPYKCNQCDKAFAHRESLITHSTTHSGIKPYYCSYCQSRFSCIGNLLKHRRARADTCGLPQYCQTNKIAARPNIKTMPNLTDRPVYTQKVVQRSSPVKSRSKPKPSEIVVSVEVVPPKKRPSKQVARPALPPPPPSTVQSDDEDDRTKDFEDEYYERKPNVAKLKVAPAAAGSKYRRLVDLKVEPGDSDEAGECSVVKVEKHAASSGDDEHVEFFEVKIEQENDELIETIEEETLEEYEEVLSEKVVTLDSKGRAVVDSDDDFNDATNEDYLEEATDEFQPPKQQDQYHDGDVVIKRKFTTKPPVVTQPKRRGRPKRPPAPKFQNVNPEHVIVINLEEKQKVIDEQRAIYDANIIEVTVGCLQCGICPAQYCSPFLAARHLERDHGIMMHELGETLRYDRVFTRERKYQCRFCNRLYVNEKALEKHILLHGPNGTAVHKCPICTSWFESEEEALNHSRIEHREKLECPVCFKFFSNQERMIKHRKQIHEQTRVKQDHVCPKCGKNFSSRGAVSDHERSNCGQNPIYPCEICGKRYNTASSLKNHYSLHSDELPFSCQYCGKCYRTRGQVKVHERTHTGEKPYACDFCPKRFGHRETLHTHRSLHTGIKRYMCSGCGMRFTCISNLQAHRRSHKTTCGMIPTYSKVRGPDGVHELPEGYELPYPLNDQET

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00401940;
90% Identity: iTF_00401940;
80% Identity: -