Basic Information

Insect: Culex pipiens
Gene Symbol: -
Assembly: GCA_016801865.2
Location: NC:57466859-57508608[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 25 0.17 5.1 8.3 0.2 2 23 209 231 208 231 0.91

2 25 3.3 1e+02 4.2 0.3 6 23 240 257 240 257 0.97

3 25 1.2e-05 0.00036 21.3 0.7 1 23 263 286 263 286 0.97

4 25 0.0016 0.05 14.6 1.1 2 23 295 316 294 316 0.96

5 25 1.2 37 5.5 2.0 1 21 324 344 324 347 0.87

6 25 0.16 4.9 8.3 1.8 1 23 354 376 354 376 0.97

7 25 4.4 1.4e+02 3.8 0.4 2 23 392 412 391 412 0.80

8 25 0.39 12 7.1 1.4 2 23 417 438 416 438 0.94

9 25 0.00025 0.0075 17.2 0.6 2 23 444 465 443 465 0.96

10 25 0.001 0.032 15.2 2.0 1 23 471 494 471 494 0.97

11 25 0.00057 0.017 16.0 1.1 1 23 1002 1025 1002 1025 0.94

12 25 1.1 32 5.7 1.4 1 23 1079 1102 1079 1102 0.89

13 25 5.5 1.7e+02 3.5 4.2 1 23 1134 1157 1134 1157 0.97

14 25 0.00028 0.0087 17.0 1.9 1 23 1165 1187 1165 1187 0.97

15 25 0.00043 0.013 16.4 1.1 2 23 1196 1218 1195 1218 0.97

16 25 0.0039 0.12 13.4 0.4 1 23 1223 1245 1223 1245 0.96

17 25 0.14 4.3 8.5 2.9 2 23 1254 1275 1253 1275 0.97

18 25 0.012 0.37 11.8 0.5 2 23 1282 1304 1281 1304 0.95

19 25 0.00017 0.0052 17.7 1.1 2 23 1310 1332 1309 1332 0.92

20 25 0.0039 0.12 13.4 3.8 1 23 1338 1361 1338 1361 0.96

21 25 0.0078 0.24 12.4 0.6 1 23 1414 1436 1414 1436 0.97

22 25 0.46 14 6.9 1.3 2 23 1445 1467 1444 1467 0.96

23 25 8.2e-05 0.0025 18.7 3.4 2 23 1476 1498 1475 1498 0.96

24 25 0.03 0.93 10.6 1.6 2 23 1504 1526 1503 1526 0.94

25 25 2.3e-05 0.0007 20.4 2.7 1 23 1532 1555 1532 1555 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	25	0.17	5.1	8.3	0.2	2	23	209	231	208	231	0.91
2	25	3.3	1e+02	4.2	0.3	6	23	240	257	240	257	0.97
3	25	1.2e-05	0.00036	21.3	0.7	1	23	263	286	263	286	0.97
4	25	0.0016	0.05	14.6	1.1	2	23	295	316	294	316	0.96
5	25	1.2	37	5.5	2.0	1	21	324	344	324	347	0.87
6	25	0.16	4.9	8.3	1.8	1	23	354	376	354	376	0.97
7	25	4.4	1.4e+02	3.8	0.4	2	23	392	412	391	412	0.80
8	25	0.39	12	7.1	1.4	2	23	417	438	416	438	0.94
9	25	0.00025	0.0075	17.2	0.6	2	23	444	465	443	465	0.96
10	25	0.001	0.032	15.2	2.0	1	23	471	494	471	494	0.97
11	25	0.00057	0.017	16.0	1.1	1	23	1002	1025	1002	1025	0.94
12	25	1.1	32	5.7	1.4	1	23	1079	1102	1079	1102	0.89
13	25	5.5	1.7e+02	3.5	4.2	1	23	1134	1157	1134	1157	0.97
14	25	0.00028	0.0087	17.0	1.9	1	23	1165	1187	1165	1187	0.97
15	25	0.00043	0.013	16.4	1.1	2	23	1196	1218	1195	1218	0.97
16	25	0.0039	0.12	13.4	0.4	1	23	1223	1245	1223	1245	0.96
17	25	0.14	4.3	8.5	2.9	2	23	1254	1275	1253	1275	0.97
18	25	0.012	0.37	11.8	0.5	2	23	1282	1304	1281	1304	0.95
19	25	0.00017	0.0052	17.7	1.1	2	23	1310	1332	1309	1332	0.92
20	25	0.0039	0.12	13.4	3.8	1	23	1338	1361	1338	1361	0.96
21	25	0.0078	0.24	12.4	0.6	1	23	1414	1436	1414	1436	0.97
22	25	0.46	14	6.9	1.3	2	23	1445	1467	1444	1467	0.96
23	25	8.2e-05	0.0025	18.7	3.4	2	23	1476	1498	1475	1498	0.96
24	25	0.03	0.93	10.6	1.6	2	23	1504	1526	1503	1526	0.94
25	25	2.3e-05	0.0007	20.4	2.7	1	23	1532	1555	1532	1555	0.98

Sequence Information

Coding Sequence: ATGGCGGAACCTGCTTGTCTAACCTGCACTAAGCAAGTTCCGGGCCTGGACCAGGCCGTTTCCGTGGGAAACCGGCAGGAAGTGCAGACTGCTCTCTCGAAGCACTTTTGGTTTAGTGAATCCGAAAGTCTGTACGGCATTCTGTGCCCCGTTTGCTGGACCAAAATCCACGACTTCCATCAATTCTACACCGAGGTGGAGAGCATCCACGCCAAACATCCGCAACTGCCCCTGCAGCTACAGCCCGATCAGTTTCTGGAGGTGAAGCAGGAGGAGCCACTGCAGGCGACGGTCTTTGTCGCCGAAGATGTCGTCGTGAAGAGCGAGGGTGACGAGTCGAATGAGGGTTCGAAAGCGGAAAGCGACGGAGatgattttgaagggggagggaaCAGTCCGATGTTGAAGGAGGAGGATTCTGAGGATGATGATGAGCTGAATGAAAGTTCCCAAGAGGATGATTCGGAGTATGAGGAAGAACCGGTGCGGAAAAGGGGAAGGAAACCTGGTTCGGGtaagaagaaggaaaaaaagaaaaccggGAAGCGAAGGGTAGGTCGACCGGTTCAAGGATGGCAGAAGGACATTCAGGATGAGAGCTTCATTGCGGAAACGGTCAATCTGGTATGTGACACTTGCAGCGAAAAGTTTGGAACGTTCGAAGATCTGCAGCAGCACTCAACGGTGTTGCACGATAAGCTGGCGTATATTTTCTGCTGTAATCTCAAGTTTTCCCGCAAGCCACGGCTCGTCGATCATATCCAGTTCCACCTCAATCCGTCCCAGTTTGCTTGCAAGATCTGTTCGAAGCAGTTTGGCGATCGGGAAGCGCTCAAGAGGCACATGCGATCGATGCACGTGGACGAGGAGGAAAAGACGCTGCAGTGTAGCGTGTGTCCAAAGAGGTTCGCGCAGAAGCGATTCCTGAACCTGCACGAAAAGTACCACCGCAATCTGCAGGAAAAGAAGTTCCACTGCGAACCGTGCAATCGCTACTTTGCGTACGCTTCTCTGCTCCGACACCACAACGAGGAAGTGCACGAGAATAAACCGGACAAGTACGTGTGTCACATCTGCGCCAAGAGCTACAACATTTACACGTCGTACAAGTCGCACGTTGACTCCCACGACGAGGAAGCCAAGAAGGTCAAACAGCTGTCGATGGAGCGGGTTCAGTGTACGGATTGTAACGCTTGGGTTTATCAGCGAGGTCTGCGCAAGCACATGCTCCGTCACTCTGGAACTCAACGGTGCGACATCTGCGGGCAGGAATGTTCGAGCGTTATGACTCTGAAATATCACAAGGCTCAGCATCGCAAAGACGATCTGACCTGCTCGGTGTGCGAGAAGGTGTTTAAGCGAATGATCAATTTTAAGGAGCACATGGCATCGCACACCGGAGACGTACTGTACTCTTGTGATTTCTGCGACAAAACGTTCAACTCGAATGCGAATCGAGCGTCGCATCGGAAAAAGATGCACCCGAAGGAGTGGCTCGAGGACAAGATGAGGAAAAATCCGAACCTGATGCAGGAGCAGTTTCAGCAGCCGCAGCAGCAACAGCCACCATTCACACTGTTCCGCATCCGTATCCGCAGTACGGATCCGTATACGGATGCGGAACAGTGTGAATGGGAACATTTGAAATGCATTGGAGGAATCGCTTCCGCACTGTGCGTCCGTACTGTCAAATTTTATACGGATGCGGCTGCGGCTGCGGATGCGAAGAAACTTCCGCGCTCGGGTGAGGTTATGTTCGCCATGGAGGATTCGCTGTTCGGAACAGATCCGGTGGACGAGTGGACCATGCACCAGCTTCGTCAAATCCTGGATCAGCAACGAAACCTCATGGAGAAACTAAACGTTCCGCCGCTGCCCGTTGTCCAGCTGGTAGCACAAGAGGACGTTCCCGACACCTGTGCACACGTGGACTTTTCTGGCGAGAGCTCGTTGGGTGCGAAGAAAGCGAAGGAGATCCGGCAACCACGAAGGCACGCGGCCGTGCTTCCAGCCGAGGAGAAGCAAAATTCATCCATCTCAGCAATCATTCAGCCGGTTGCCACCAAGAACCTCGATCATTACACGCTGCCCCCATCGGAGACCATCTTCAACAAGATGGCGGAGCGCAGCAGCACCACCCTGTCAGCCATCGGTCCGCAGCAGCTACCAATCATCACCACAACACACACCCCGGATAACACATCAGCACCGGAGGATCAGCAGCAGTTGGTGAACAACACGGTCGGCACTCTCAGCGGCACAGGGCACACCGATGACATCTTGGTTGGTGACCAATCGAAGCCAATTAGAACCATACCAGATCCCGGCACAATGGACCGCACCGCTTGTTTGACCTGCTTGCAGCAACCGGACGACGAAACAGATCAGCAAAACATCTGCCACTCGGATTTGCGTGAAATCGTGCGAAAACACTTTTGGTTCTCGGATGCGGAGCTAGCTCAGGCTTGGATATGCGAGGTCTGCTGGGAAACCATCAGCGTGTTTCATCAGTTCTACGTGGATGTCGAGCAGCTGTATGAAACGAAGCCGGTTCCGGAACTGGAAGCGGTGACCGTCAAGGAGGAGAAGGACATTACCCAGGTTATGCTGGTTGAAAACGAAATTAAAGAGGAAGTACTCTCGGACGATATGCAGGAAGAGTTTGAAGACGAACAGCTCTACACGGTGGAACTGAAAGAAGGTGAGGAGCAGGAAAGTGAAAGTGATTCCAATTCTGATTCCGATGATTCGATGAGCGGTGAGAATGAAGCCGACTCTGAGTCAAACCTCGGTGAAAACCATCCGGACAACATTATCCGACGGCATGTTGAGCTGACCTGCCAAGAGTGCGACGATGCTGGAAGTTTTACGTTCAAAGAGTTCACCATTCATGCCGAAAAGATTCACGGAACCAAGAAACCGTTCGTGATGTGCTGCGGATCCAAGTACATCAAGCGGTGCTATCTACTGGAGCACGTACGCTACGTTCTCAATCCGGATGCATTCCTGTGCAAGCACTGTGACGAGGCATTTACCAGTGGAGTTGCCCTCAAACGGCACCTTAAAATTCGTCACGGTAAAGGGCAAACCCGTCGATACAATAACGAAAATCGGCTGCGAAAGGACAAATCAGCTCCGGTTAAAAATGAAGAGCAGCTAAAGAAGCGCGAAGAGATTGAGCTCAAACGACAGCAGCGAGCGGCTGACGATCAGATCATGCTTGGCCACGTAAAGTTCGAGTGTGTTCCCTGTGGTGAGTCCTTCATCTCCTTCACGCAACTGCACACCCACAGCACGTCCAAGCACAAGATCAAACCGGTGGTCACGTGCTGCGGGAATCGATACAACAGCCGATGTAAGCTGTGGCAGCACGTCACGTCGGTTCTCAATCCGGTCGCCTATCGGTGCGAGCTCTGTATGCGATGCTTTAACAGTGAGTACGCCAAGGATACCCATCGGCGGAAAATGCATCCGACCGCGGAGGAGCTCAAGTACCACTGTGAGCGGTGCGACAAGCCGTTCTCGAGGGAAATTGCTTACAAGCGACACATGCAGGACCACGAGGACTCGGATCATGGGCGGATCAAGTGTGAGGAGTGTGGCAAGATGTTCAAAAGTCGCACGGTTCTGTACATGCACGTGCGCAAAAAGCACGTGGCGCCCCAGTTTGTGTGCGACATTTGCGCGAAGGCGTTCCACCAACCGGCGGAGTTCGAGAAGCACAAGCTGGAGCACGAGGATCCGGACAGACTGCGGATGCAGTGCCAGCACTGCCTAAAGTGGTTCAAAAACCGCGAGTACTGGCGCACGCACATCCGGCTGCACAATCCGACGACGCCGGTTCCGTGCGAACTGTGCGATCGCGTTTGCCAGAATAAGCGGGCGTGGCGGGCACACATGAAAAATGCTCACGGTACGCCCGACAAGGTGTGTGAGCTGTGCGGCAAATGTTTCAAGAAGAAGCAAAGTCTGCAGGAGCACATTGCTGCGGTCCACACGGGACAGAAGCTGTTTAGTTGTCCCTTTTGTCCGCGGAACTTTAACTCGAGCTCGAACATGCATACTCAcaagaaaaatatgcacaccGAGGAATGGCAAGCGTCGAAACTGGGCGCGGTCGCGACTACATCCTTTGCTGGTCCGAGTGAGACAGATATGACGAAGGATGGAGCGTTTTTGCACTACAAAAGCCACGCCGTACTCTACGTGCACATCCGCAACTATCACACGGAGCCACGCTTTGTGTGCGACATTTGTGCGAAACCATTCCGTATAATGTCAGAGTTCAAGAAGCACAAACTATCCCACGAAGATCCGGACAAGCTGAAAATGCAGTGTCCTCATTGTATGAAGTGGTACAAAACCCGTGAATACTGGCGCGCTCACATTCGACTGACGCACCGTtcgaagcaaaatcaaatgatcaaatgtgaAAAGTGCGAAAAGACCTTTTCTCGCAAGGACAAAATGCGAGCCCACATGAAGCACGTCCACGATGAGCCCACCAAAAAGTGCGAGTATTGCGAAAAGTGCTTCGTGAAGGACATTAGCCTGCGGGAACACGTGGCCTCCCAGCACACCGGCGAAGTGCTGTACACGTGCACGTACTGTCCGAAGACGTTCAACTCGAACGCGAACATGTTCTCGCACAGGCGCAAAATGCACCCGGTGGAGTGGCTGGCCGCGAAGGAACGCTCCGAAGCGGCCCGGCAACGGGCTGATTTGGTGGAGAACGTTGCCTCAGAGTCGGCGAACGGAACCAGCATGCAACATGACTATTGA
Protein Sequence: MAEPACLTCTKQVPGLDQAVSVGNRQEVQTALSKHFWFSESESLYGILCPVCWTKIHDFHQFYTEVESIHAKHPQLPLQLQPDQFLEVKQEEPLQATVFVAEDVVVKSEGDESNEGSKAESDGDDFEGGGNSPMLKEEDSEDDDELNESSQEDDSEYEEEPVRKRGRKPGSGKKKEKKKTGKRRVGRPVQGWQKDIQDESFIAETVNLVCDTCSEKFGTFEDLQQHSTVLHDKLAYIFCCNLKFSRKPRLVDHIQFHLNPSQFACKICSKQFGDREALKRHMRSMHVDEEEKTLQCSVCPKRFAQKRFLNLHEKYHRNLQEKKFHCEPCNRYFAYASLLRHHNEEVHENKPDKYVCHICAKSYNIYTSYKSHVDSHDEEAKKVKQLSMERVQCTDCNAWVYQRGLRKHMLRHSGTQRCDICGQECSSVMTLKYHKAQHRKDDLTCSVCEKVFKRMINFKEHMASHTGDVLYSCDFCDKTFNSNANRASHRKKMHPKEWLEDKMRKNPNLMQEQFQQPQQQQPPFTLFRIRIRSTDPYTDAEQCEWEHLKCIGGIASALCVRTVKFYTDAAAAADAKKLPRSGEVMFAMEDSLFGTDPVDEWTMHQLRQILDQQRNLMEKLNVPPLPVVQLVAQEDVPDTCAHVDFSGESSLGAKKAKEIRQPRRHAAVLPAEEKQNSSISAIIQPVATKNLDHYTLPPSETIFNKMAERSSTTLSAIGPQQLPIITTTHTPDNTSAPEDQQQLVNNTVGTLSGTGHTDDILVGDQSKPIRTIPDPGTMDRTACLTCLQQPDDETDQQNICHSDLREIVRKHFWFSDAELAQAWICEVCWETISVFHQFYVDVEQLYETKPVPELEAVTVKEEKDITQVMLVENEIKEEVLSDDMQEEFEDEQLYTVELKEGEEQESESDSNSDSDDSMSGENEADSESNLGENHPDNIIRRHVELTCQECDDAGSFTFKEFTIHAEKIHGTKKPFVMCCGSKYIKRCYLLEHVRYVLNPDAFLCKHCDEAFTSGVALKRHLKIRHGKGQTRRYNNENRLRKDKSAPVKNEEQLKKREEIELKRQQRAADDQIMLGHVKFECVPCGESFISFTQLHTHSTSKHKIKPVVTCCGNRYNSRCKLWQHVTSVLNPVAYRCELCMRCFNSEYAKDTHRRKMHPTAEELKYHCERCDKPFSREIAYKRHMQDHEDSDHGRIKCEECGKMFKSRTVLYMHVRKKHVAPQFVCDICAKAFHQPAEFEKHKLEHEDPDRLRMQCQHCLKWFKNREYWRTHIRLHNPTTPVPCELCDRVCQNKRAWRAHMKNAHGTPDKVCELCGKCFKKKQSLQEHIAAVHTGQKLFSCPFCPRNFNSSSNMHTHKKNMHTEEWQASKLGAVATTSFAGPSETDMTKDGAFLHYKSHAVLYVHIRNYHTEPRFVCDICAKPFRIMSEFKKHKLSHEDPDKLKMQCPHCMKWYKTREYWRAHIRLTHRSKQNQMIKCEKCEKTFSRKDKMRAHMKHVHDEPTKKCEYCEKCFVKDISLREHVASQHTGEVLYTCTYCPKTFNSNANMFSHRRKMHPVEWLAAKERSEAARQRADLVENVASESANGTSMQHDY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -