Basic Information

Insect: Culex pipiens
Gene Symbol: -
Assembly: GCA_016801865.2
Location: NC:185094644-185099327[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 19 8.6 2.6e+02 2.9 3.7 1 21 233 253 233 255 0.88

2 19 0.011 0.33 12.0 0.6 1 21 267 287 267 288 0.94

3 19 2.2 69 4.7 1.3 3 23 342 364 340 364 0.90

4 19 0.0029 0.089 13.8 3.1 1 21 378 398 378 399 0.94

5 19 0.0002 0.006 17.5 0.5 2 23 406 427 405 427 0.97

6 19 0.0046 0.14 13.2 0.4 3 23 435 455 433 455 0.97

7 19 6.5e-06 0.0002 22.1 1.1 1 23 461 483 461 483 0.97

8 19 0.15 4.5 8.4 1.3 1 11 489 499 489 500 0.95

9 19 0.59 18 6.5 0.5 1 23 713 736 713 736 0.94

10 19 0.041 1.3 10.2 0.2 3 21 750 768 749 769 0.93

11 19 2.9 89 4.4 0.2 3 23 818 840 816 840 0.87

12 19 0.00087 0.027 15.4 1.4 1 21 854 874 854 875 0.94

13 19 0.00039 0.012 16.5 1.8 1 23 881 903 881 903 0.97

14 19 1.3e-05 0.00039 21.2 0.1 1 23 909 931 909 931 0.98

15 19 0.00038 0.012 16.6 3.3 5 23 941 959 937 959 0.91

16 19 4.8e-06 0.00015 22.6 4.3 1 23 965 987 965 987 0.98

17 19 0.0091 0.28 12.2 1.3 2 23 994 1015 993 1015 0.95

18 19 0.00038 0.012 16.6 2.5 1 23 1021 1043 1021 1043 0.98

19 19 1.5e-05 0.00045 21.0 0.7 1 23 1049 1071 1049 1071 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	19	8.6	2.6e+02	2.9	3.7	1	21	233	253	233	255	0.88
2	19	0.011	0.33	12.0	0.6	1	21	267	287	267	288	0.94
3	19	2.2	69	4.7	1.3	3	23	342	364	340	364	0.90
4	19	0.0029	0.089	13.8	3.1	1	21	378	398	378	399	0.94
5	19	0.0002	0.006	17.5	0.5	2	23	406	427	405	427	0.97
6	19	0.0046	0.14	13.2	0.4	3	23	435	455	433	455	0.97
7	19	6.5e-06	0.0002	22.1	1.1	1	23	461	483	461	483	0.97
8	19	0.15	4.5	8.4	1.3	1	11	489	499	489	500	0.95
9	19	0.59	18	6.5	0.5	1	23	713	736	713	736	0.94
10	19	0.041	1.3	10.2	0.2	3	21	750	768	749	769	0.93
11	19	2.9	89	4.4	0.2	3	23	818	840	816	840	0.87
12	19	0.00087	0.027	15.4	1.4	1	21	854	874	854	875	0.94
13	19	0.00039	0.012	16.5	1.8	1	23	881	903	881	903	0.97
14	19	1.3e-05	0.00039	21.2	0.1	1	23	909	931	909	931	0.98
15	19	0.00038	0.012	16.6	3.3	5	23	941	959	937	959	0.91
16	19	4.8e-06	0.00015	22.6	4.3	1	23	965	987	965	987	0.98
17	19	0.0091	0.28	12.2	1.3	2	23	994	1015	993	1015	0.95
18	19	0.00038	0.012	16.6	2.5	1	23	1021	1043	1021	1043	0.98
19	19	1.5e-05	0.00045	21.0	0.7	1	23	1049	1071	1049	1071	0.98

Sequence Information

Coding Sequence: ATGAACGTTTGCCGTGCTTGTGTGAGTAGCAGCTCTGGTGATTTGGTGCCGATATTCTCCAAATTGGGTGATCAATTCATCGCGAATGTTATCGTAGATTGCAGCTCAGTGACGATTGTCGAAGACGACGGCTTGCCATCGTTTGTTTGCAAAGAATGCCTCACAAGTGTACAAATGATTGCCGATTTCGCGACAAAGGTCCGCGAGTCCGATCGCAAGCTCCGCCAGCTGTTCAAATCCGAAGTCACACTCAAAGCCATTGAGGAACCGAATACCGAGGAGGGTGAGTCCGATGTATTGAGCACGGCACTGGATCAGGTCAAAGTGGAGTACGATGACGATGTGGAGAAGGTGGAAAAGTCCGTTTCTGAGTCTGAGGGGGAGTCAGAATCGGATGCTTTGGATTTTGAGGATGGCAACGATAGTGACTGGAATGACGCCGAGCagaaacagtcagaagatgagcTGGAGATCGCGACAGCTAAACGCAAAACTAAGCAAAAAGCGGTGGTTGAGCAGGACTCGGATGAAGATGAGGAAGAGGCATCGTCGTCGAAACGTCCTAAGCGACGGTCAGCTAAGAAAAAGGTAGTCAAGgatgatgacgacgatgatgaaGATGATGATATGGCGGAGGATACAATGACTGAAATGGAGCAGGAGATGTTTGAACTGGTCAAAATAGATCCTGCTAGGCACATTTGTTGTTGGTGCTGTAAGGATTTCGAAACCAGGGACGAGTTGAAGGCACATGGCGTGGAACATAACGATCGGAGAAGGCGACAAACATATAAACCGCACTCTTGCGAAATTTGCTACCGCCGATTCATTAGGGTGAAATCGTTCGAGAACCACATGATAATGGCAGCGGGTTTGTCAGCTAAGGAGATCCATCAGTGCAAACGATGTTCGGCTCGCTTCCTGGCACCCAAGCGGAGACGCATGCATGCACTATGCCACCACAAGGAGGATGAAAAACTTGCCCAATTGGAGCTCAAGCGCAAGAAGAAAACCCCAACCTGTTGCAATCGTTTCTGTTACCAAGAGTTCACAACAGAGGAAGAATTGCTGGAGCATGGTCTGAAGGAGCACATCAGTAACAAGCGCGCGGAGGTGGATCCGAAGCAACCGCACGAGTGCCCCGTGTGCTATAAAAACTTCGAAAGCAAGAAATCACTGCATCGGCATCGAAACAGAATCTACCGTGCAGGAATGCAATGCTCGATTTGCGGCAAAGAGTTCAAGTCACGACCCGCTATGATGACACACGAACGCAAGCACGTAGACGAGCGTCCGTACGGTTGTGAAATCTGCGGCAAGTGGTTTACGACCACGCACGGGCTCAAGAATCACCTCGCGGTCCACAAAGATGAGCGCCCGTTTGCGTGTTCCGTGTGCGGCTGGAGCTTCAAGCGGGAGTGCAATCTGAAGATGCACATGCTGATCCATTCCGATACGCTGCCATTCAAGTGCGAAGTGTGCGGAAAGTCGTTCAAGATCTTCGAAGACGATGGCCTACCGACCCAGATCTGCTCGACATGTCTCAGCGATCTACGCCAAACGAAAAATTTCGTGCGGAAGGTTCGCGCATCGGATCGCAAGCTGCGCCGATCACAGCGCAGCGAATTGTGTGAGGTCGAAAAGCTGGACAGCGGAGATCACGTCGACGATGACGATTCGCCGTGGCAAATGATACAGGTGCACGTGGAGGAGATGAAGCTGGAGAAGGAAGATGAAACGGAGAGCAATTCTGGGGCAACCAGGGCGAGGAAGTCTCGGCGAATGGTGAAGCGGACGCGGTTTGCACCGAGCGATTCCGAGGAGGATGAATCGGTCGACGAGCTGCACAAGTTGTTCAAGAAGAAGGTAACGTGCAAGGATGATGACGACGATGCACCGATGGAGTTGTCCACGGTTAAGCGACAGATGATGCGGAGGCAGAAGCGTAGAGTAGTGGACGATTCTCAGTCTACTGAAAGTGAGACGGATTCCGAGCCAGTTATCAGACGCAGACGAAAGCCACGAGCCCGAAAGAGAGAGAACAGTCTCGCGAAGCATGATTATTCGGAAGATGAGCATATTCCCAGCGAAACACTGCACGAAATGTACCGGACAGTGTCGGTCGATCCCGATACTCATGTATGCTGCGCTTGTTTGAGGATCTTCACCGATCGAGCGGAGCTTGTGGAGCATGGGAAAGTTgcgcacaacaaaaaaaagtacgtCAATGAAGCCAAAACGAACATCTGCGATGTCTGCTTCCGGCGGTACTCGAAGGCAAGCGCGTTGCAAACACACAAGCAGAGTTTTGTAGGACTAAACGGAGTGTATGAGTGCTGTCGATGCATGACACGGGTGACGGCTCAGAACCGTCGGCAGCATGCGCGGATTCATCTGAAGCATCGTGACGAACTGACGGACCATGAGAAACCCCGACGGGCACAAATTTGCTGCGCAAAAGACTGTCTGGCATCCTTTCCCACTGAAGATCTGTTGTTGGCCCATGGAAAAGAACAGCACATCGACAATAGAATCGAATCGGACGATCTGGAACGCCGGTACGAGTGTCCGGTATGTTTCAAGCGGTTCGAGAAGCGTGATGGCCTGACTCGTCACCGACATCGAATGTATCGGGCAACGCATCAATGTTCTGTATGCGGGAAGGAGTTCAAGACACGGTATGAAGTGTTGCTCCATGAGCGGAACCATGATAACATTAAGCCGTATCCGTGCGAAATTTGCGGGAAGAAGTTTAACTCTAGGGAAGCGGTTCGTATTCATATGTTGGTGCATTCAGATGATAAGCCGTTTGCTTGCATTTCTTGCGGATGGCGCTTCCGGCGGAAGTGTAATCTAAACAAGCACATGATGAAACATAAGGAGGATACTCCTTATTCGTGTAGTATCTGTCAGAAGACGTTTAAGGGAAAATACCATCTTCAGTATCACATGCGTATTCACACTGGTCACAAACCGTGGCAATGTCGGTATTGTGAGAAGTCCTTCGCAGATCATGCCAACAGGGCTCGTCATGAGACATCACATACAGgCATTAAACCATACAAATGTACGTACTGCGATAAAAGTTTTATCCGTAAACGTTATCAGATCGAACACGAGAGTACACATACGGGAATCAAACCGTACCGCTGCGAAATGTGCAATCGAACGTTTGGCCAGAAGGCGGCCCTCAAGAAGCATCTGGATATGCACCCGCTGGCGCCAGAGAATCAGCTCTCGTTGGCTCAGCCCTCGCCGATGGCCGAGATGCCCATGTCGCCGCAAATGCCCCCACCGCCGGCCCCGACCACGGTTGCGCAGGGGATGACCTTGCAGCAGGCGGCCGTCATGATGGCGGGTTCCGGCGCCGGGTACAGCCAGCAGCCGATGTAA
Protein Sequence: MNVCRACVSSSSGDLVPIFSKLGDQFIANVIVDCSSVTIVEDDGLPSFVCKECLTSVQMIADFATKVRESDRKLRQLFKSEVTLKAIEEPNTEEGESDVLSTALDQVKVEYDDDVEKVEKSVSESEGESESDALDFEDGNDSDWNDAEQKQSEDELEIATAKRKTKQKAVVEQDSDEDEEEASSSKRPKRRSAKKKVVKDDDDDDEDDDMAEDTMTEMEQEMFELVKIDPARHICCWCCKDFETRDELKAHGVEHNDRRRRQTYKPHSCEICYRRFIRVKSFENHMIMAAGLSAKEIHQCKRCSARFLAPKRRRMHALCHHKEDEKLAQLELKRKKKTPTCCNRFCYQEFTTEEELLEHGLKEHISNKRAEVDPKQPHECPVCYKNFESKKSLHRHRNRIYRAGMQCSICGKEFKSRPAMMTHERKHVDERPYGCEICGKWFTTTHGLKNHLAVHKDERPFACSVCGWSFKRECNLKMHMLIHSDTLPFKCEVCGKSFKIFEDDGLPTQICSTCLSDLRQTKNFVRKVRASDRKLRRSQRSELCEVEKLDSGDHVDDDDSPWQMIQVHVEEMKLEKEDETESNSGATRARKSRRMVKRTRFAPSDSEEDESVDELHKLFKKKVTCKDDDDDAPMELSTVKRQMMRRQKRRVVDDSQSTESETDSEPVIRRRRKPRARKRENSLAKHDYSEDEHIPSETLHEMYRTVSVDPDTHVCCACLRIFTDRAELVEHGKVAHNKKKYVNEAKTNICDVCFRRYSKASALQTHKQSFVGLNGVYECCRCMTRVTAQNRRQHARIHLKHRDELTDHEKPRRAQICCAKDCLASFPTEDLLLAHGKEQHIDNRIESDDLERRYECPVCFKRFEKRDGLTRHRHRMYRATHQCSVCGKEFKTRYEVLLHERNHDNIKPYPCEICGKKFNSREAVRIHMLVHSDDKPFACISCGWRFRRKCNLNKHMMKHKEDTPYSCSICQKTFKGKYHLQYHMRIHTGHKPWQCRYCEKSFADHANRARHETSHTGIKPYKCTYCDKSFIRKRYQIEHESTHTGIKPYRCEMCNRTFGQKAALKKHLDMHPLAPENQLSLAQPSPMAEMPMSPQMPPPPAPTTVAQGMTLQQAAVMMAGSGAGYSQQPM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -