Basic Information

Insect: Culex pipiens
Gene Symbol: -
Assembly: GCA_016801865.2
Location: NC:201483606-201516522[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 2.5e-05 0.00075 20.3 2.3 1 23 302 324 302 324 0.95

2 11 5.6e-06 0.00017 22.3 0.3 1 23 330 352 330 352 0.98

3 11 0.0054 0.17 13.0 0.2 1 23 358 381 358 381 0.89

4 11 0.0044 0.13 13.2 4.0 1 23 387 409 387 409 0.98

5 11 0.0021 0.063 14.3 3.5 1 23 415 437 415 437 0.98

6 11 0.0001 0.0031 18.4 3.5 1 23 443 465 443 465 0.98

7 11 0.00044 0.013 16.4 0.4 2 23 472 493 471 493 0.93

8 11 5e-06 0.00015 22.5 1.5 1 23 499 521 499 521 0.99

9 11 0.00022 0.0066 17.3 4.1 1 23 527 549 527 549 0.98

10 11 7.2e-05 0.0022 18.9 0.6 1 23 555 577 555 577 0.95

11 11 2e-06 6.2e-05 23.7 0.5 1 23 583 605 583 605 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	2.5e-05	0.00075	20.3	2.3	1	23	302	324	302	324	0.95
2	11	5.6e-06	0.00017	22.3	0.3	1	23	330	352	330	352	0.98
3	11	0.0054	0.17	13.0	0.2	1	23	358	381	358	381	0.89
4	11	0.0044	0.13	13.2	4.0	1	23	387	409	387	409	0.98
5	11	0.0021	0.063	14.3	3.5	1	23	415	437	415	437	0.98
6	11	0.0001	0.0031	18.4	3.5	1	23	443	465	443	465	0.98
7	11	0.00044	0.013	16.4	0.4	2	23	472	493	471	493	0.93
8	11	5e-06	0.00015	22.5	1.5	1	23	499	521	499	521	0.99
9	11	0.00022	0.0066	17.3	4.1	1	23	527	549	527	549	0.98
10	11	7.2e-05	0.0022	18.9	0.6	1	23	555	577	555	577	0.95
11	11	2e-06	6.2e-05	23.7	0.5	1	23	583	605	583	605	0.99

Sequence Information

Coding Sequence: ATGGCGCCAAAGAGATTCACCCTCAACCGGGATTCCGAGAGCCATTCGAAGTGCTCTGTGACCAAGAGTACGAAGGTGGCGGTTATCGTGATCCAGAATCGCTACGATGGATCGGTACACTTCTATCGAGATTGGGACGAGTACGAGCGTGGGTTCGGCAACATGTTTGGAGAGTTTTGGCTGGGATTGAAGCAGATTCACGAACTGACCTATTCGATGCGTTACGAGCTGCACGTAATAGTTGAAGATTGGGACGGAATCCGGGCTGTTGCAAAGTACAGCGATTTCCTGGTGGCAGGACCTAAGGAGAAATATCTACTGCGCAGCTTGGGAGCGTTTAGTGGCAGTGCAGCCATTTATGCTCCAAAATTTGCCTCCATTACAAACGACTCTTTTTTCCCTCCCACACCCAGCTTCAACCTGGAGCTGGACGAGCACGCCCTGGACTACAGCATCCAGTCCATCATAGCGGCGGACGGCGGAGAATCCCTGTTCAGCACACTGTTCCAACAATCGCCATCCAGTCCCACCGCTAaccaggacgacgacgacgacgatggccaAACATCGTTCCTGTCGTCCACCACATCATCATCGTCGGAGGAACTTGGCCTGACCTCGGCACTGTTCCCGCTGGACGCCATCATCCTCCAGCAGCCGCCGTCGCCGCCACTTTCAACGTGCTCTGCGCCGACAACGACGTCCCTGAAGACCCACAAATGCATGGACGGCGAAGAATACGGCAGGTTAAGTGACCACGATTCGGGCAACGCGTCTACGCTGGATTCCGGCATAGAGGAGACACTTTCTGAGACCACACCAACATCCCCCGAGGGCTCCACCAACGGTAGCGACGCGGAAAACGATGCGCCGGATTATGCGGCGACGGAAGCAGCGCGTCCCTTCAAATGCTCCGAGTGTGGCAAGAGCTACACCCGCAAGCTGTATCTGATGCGACACTACGTCCAGCACACCCGCGAGCGCCCCTACCAATGCGACGGCTGTGACAAAGCGTTCGCGTACGCCAGCTCGTTGTCCTCGCACCGGAAGCTGCATCTGGCCAGCGGCGAACATCGGTGTGAAATTTGCAGCAAAAGCTTCGTCAGTGAGGCGCTCGTTGAGGCTCATAAAACGGCGGCTCATTACGGGGAACGGCCGTACAAGTGCAAACTGTGCAAGAAGAGTTTTGTCCTGCTGCACGCGTACAACTCCCACAAGCGGTGGCACGCCCAGTTTAATCCGTTCCGGTGTGGAGTGTGCGACAAACAGTTTACCAAGAAAATCAGCCTCAAGTGTCATCTGAGGGTTCACACGGGCGAGAAACCGTACAGTTGTGAAGTATGCCACAAGAGCTTCACCCTCTCGTCCACACTTTCTTCGCACAAACGTCTTCACGGCAGCAAGCCCACCCTCCAGTGTGACACCTGCGGCAAAATCTTCACCCAAATATCGGCCCTCTCAACCCACAAATATCTGCACACGGAGTCAAGACCGTACAGCTGTGACCTGTGCGGCAAGCGCTTCATCCGTCTCCACGCCATGAAGATCCACATCCGGACGCACTCGAACGAGCGACCCCATCGTTGCGAGCTCTGCCCGAAGACCTTCACCGAGAAGCACGTGCTGGTGCGGCACCTCAAGACCCACAGCAACGAACGGCCTCACGCCTGCGACAGCTGCGGCAAAGCCTTCAAGGAGAAGTACGACCTGCTCCGGCACGTCCTCATTCACACCGGTCGGCGCCCGTACGAGTGCGAGCTGTGCCCGAAAACTTTCGTCCAGTCGAACGCACTGGCCAAGCACCGGCGGAAGCACGAGCGGGAGCAGCAGCTCAAGACGATGCAGGCCAGGGCGGTGGAGGGTGGAGTTGGTGCAACGGAAGTCTAA
Protein Sequence: MAPKRFTLNRDSESHSKCSVTKSTKVAVIVIQNRYDGSVHFYRDWDEYERGFGNMFGEFWLGLKQIHELTYSMRYELHVIVEDWDGIRAVAKYSDFLVAGPKEKYLLRSLGAFSGSAAIYAPKFASITNDSFFPPTPSFNLELDEHALDYSIQSIIAADGGESLFSTLFQQSPSSPTANQDDDDDDGQTSFLSSTTSSSSEELGLTSALFPLDAIILQQPPSPPLSTCSAPTTTSLKTHKCMDGEEYGRLSDHDSGNASTLDSGIEETLSETTPTSPEGSTNGSDAENDAPDYAATEAARPFKCSECGKSYTRKLYLMRHYVQHTRERPYQCDGCDKAFAYASSLSSHRKLHLASGEHRCEICSKSFVSEALVEAHKTAAHYGERPYKCKLCKKSFVLLHAYNSHKRWHAQFNPFRCGVCDKQFTKKISLKCHLRVHTGEKPYSCEVCHKSFTLSSTLSSHKRLHGSKPTLQCDTCGKIFTQISALSTHKYLHTESRPYSCDLCGKRFIRLHAMKIHIRTHSNERPHRCELCPKTFTEKHVLVRHLKTHSNERPHACDSCGKAFKEKYDLLRHVLIHTGRRPYECELCPKTFVQSNALAKHRRKHEREQQLKTMQARAVEGGVGATEV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -