Basic Information

Insect: Culex pipiens
Gene Symbol: -
Assembly: GCA_016801865.2
Location: NC:85864411-85894952[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.0061 0.19 12.8 0.1 1 23 150 173 150 173 0.91

2 13 1.4e-05 0.00044 21.1 2.8 1 23 195 217 195 217 0.97

3 13 1.6e-06 4.9e-05 24.1 4.7 1 23 223 245 223 245 0.99

4 13 0.00032 0.0098 16.8 1.4 1 23 251 274 251 274 0.95

5 13 0.015 0.47 11.5 0.8 2 23 286 308 285 308 0.94

6 13 6.3e-05 0.0019 19.0 3.1 1 23 375 397 375 397 0.96

7 13 9e-07 2.7e-05 24.8 1.5 1 23 403 425 403 425 0.98

8 13 9.7e-05 0.003 18.4 0.4 1 23 432 454 432 454 0.97

9 13 0.033 1 10.5 2.0 1 23 461 484 461 484 0.97

10 13 3.1e-06 9.5e-05 23.1 0.8 1 23 627 649 627 649 0.99

11 13 5e-05 0.0015 19.3 1.1 1 23 655 677 655 677 0.99

12 13 0.0086 0.26 12.3 0.1 3 23 686 708 684 708 0.92

13 13 7.6e-05 0.0023 18.8 1.9 1 23 714 736 714 736 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.0061	0.19	12.8	0.1	1	23	150	173	150	173	0.91
2	13	1.4e-05	0.00044	21.1	2.8	1	23	195	217	195	217	0.97
3	13	1.6e-06	4.9e-05	24.1	4.7	1	23	223	245	223	245	0.99
4	13	0.00032	0.0098	16.8	1.4	1	23	251	274	251	274	0.95
5	13	0.015	0.47	11.5	0.8	2	23	286	308	285	308	0.94
6	13	6.3e-05	0.0019	19.0	3.1	1	23	375	397	375	397	0.96
7	13	9e-07	2.7e-05	24.8	1.5	1	23	403	425	403	425	0.98
8	13	9.7e-05	0.003	18.4	0.4	1	23	432	454	432	454	0.97
9	13	0.033	1	10.5	2.0	1	23	461	484	461	484	0.97
10	13	3.1e-06	9.5e-05	23.1	0.8	1	23	627	649	627	649	0.99
11	13	5e-05	0.0015	19.3	1.1	1	23	655	677	655	677	0.99
12	13	0.0086	0.26	12.3	0.1	3	23	686	708	684	708	0.92
13	13	7.6e-05	0.0023	18.8	1.9	1	23	714	736	714	736	0.97

Sequence Information

Coding Sequence: ATGATGGAGCCGAATCGTGAGCTTCCCCCCGTCCCTGTATCGTGTTGTTTTTCCACGCGAAAGGAAACCGACCGCCGACATCACATCGCAAAAACAAACAtcaccaacgacgacgacggcgccaTCGCGCACAAATACACGCTCACCAGCGAAGGATCCAACCAGCCAACCATCATCGAGCAGCCACGGTTTGGCCTCGGAAAACACGTCAGCCAGGCATCACTGCTGATGCTGCAGTCCGATCAAAGTGCTAACAGTGTTTTTACAGATCTACGAACAACGATCAGTCCAACATGGAAGAAGCGAACTGCCCAACTTCAACATCACAAGAACCAGTATCAACCGATCAAGAACCGatgcacccaaaggaaaaatatatctcaaaatctgcaacagtggatttgctgcagaaaatgtcacatcgAGCGGCACTACGCGAGCGAGGACCACACGTGCGCGGTTTGCGACCGGGAGTTTGGCTCGCTCGAGGAGCTGAAGGCGCACGTGTACGAGGGTCATGAGGAGGGCAATCGGCGGGCAGTTGGGAAGATCAACGTTGTGCAAGGGTTTGTCAAGAAGTTGCACGAGTGCAagttttgcgacaagactttcCCCAAGAAGAGCCTGCTGGAAAGGCACTATTTGGTGCACACGAAGCAGAAGCCGTTCAAGTGCGAAATCTGCTCCAAATGCTTCAACCAAAAGTCCACCCTCAAAACGCACATCCTCACCCACAACGGCGTCCAGGACTTCCGGTGTTTGCTGTGCGGACTGAAGTTTTCCCAGAAAATCAACCTGCGCGTTCACACATTTCGGATGCATCCCAAACGGACCGCATCCGTGGCCGATCGCCTGCCGTGTCCGTACTGTCCGTGTCTGTTCAAGAAGTTGGGCAGTCTGAACGCGCACAAGACGAAGGTGCACGCGGCTCTGCTGCCGGATCCGACGACGGTTGAGGAACCTCCGGTTAAAAGTGTTCCGGAAGTagttcaagtttttgaagatctCGTGAAAATGTCTAAGAATGTTGTCGCTTGTGACAGCTTGGAACCGGAAGTGGTTCAACCTATAATAGCATGTCGAACCCAGCACCATCTAGAGGGTAAATCCGAAGACCGCCAGCATGCTTGCACAATTTGTCCGGCTGCCTTCAAGAAGTCAAGCCATCTAACGCAGCACACCCGATCGCATTACGGAATCAAAAGCTATCGTTGTGAGATTTGCGACAAAACTTTCACCACAAATCGCTCGCTCAAAATTCACCGAATCAGCCACAGTTCAACCGTTCCGGACTTCCGGTGTGACCAATGTCCGGCGAGTTTCAATCTGCAATCCAGCTTACGACGACACACCGCCATTCACGACAACCCCGATCGCAGCTACAGCTGTCCAATCTGCAAGCGGATCTTCAAGTGGTTACAAAACTGCAAGGCTCACATCCGGACAAGTCACGGCAAGGAAGGCGCACCTGTATCGCTTATTACGGCGGAGCAATCAACGAAGCTGGAAGCAACTCAAGAACCACACGACGCAACGCTGCTCGATTTGAAAAACCTCCCGCCGAACGTCCAAATCTACGACATCAACAGCCTGACCAACTGTCTGGTGCGCATCGATGACCAATTCTACGAACTTCCGGTGCAGATCGACACGGATCAGCTAACGCAAGACCAGCACATTGTCGAAATCGTCCAAGAAGTCTCTACCGAGCAGATGTACATCCTCCCCGAGAGCGAAATAATCCAAGAGGAAGTGCTCGACCAATCCGACACCCCAGAACCACCGGCGGAACCAAAACCCAAAGCAAAAGACAAAAAACTCCCCAACGTTACCGAGCAGGACCTCTTCTCGGAAGGTCTCGTCAACGGCAAAAAGTGCTACTCCTGCAAGGCGTGCCAAAAGCCCTTCAAGAAGCCGGTCGACCTCCGCAGACACATCCGCACCCACACCGGGGATCGCCCCTTCAAGTGTGATCGCTGCCCAAAGTCCTTCACCCTGAAGGCGGTCCTCCAAGCACACCGGAAAACGCACGAAGAACGTCGCGAGGTACTGTTCTGTTCGGAGCCGCAATGCGAGGCCAAGTTTTCCAGCAAAGCGGCCCTCGAGATGCACCGCCGGATTCACACCGGGCAGCGGCCGTTCCGCTGTACGGTTTGTACGCTCACGTTCCGCACCTCCGGCCACATGCAGGCGCACATGGTCTCCCACGAGCGGTTGGCCGCGAAGCGGGAGCAGAACCTGCTGCAGTTTGGAACGTAG
Protein Sequence: MMEPNRELPPVPVSCCFSTRKETDRRHHIAKTNITNDDDGAIAHKYTLTSEGSNQPTIIEQPRFGLGKHVSQASLLMLQSDQSANSVFTDLRTTISPTWKKRTAQLQHHKNQYQPIKNRCTQRKNISQNLQQWICCRKCHIERHYASEDHTCAVCDREFGSLEELKAHVYEGHEEGNRRAVGKINVVQGFVKKLHECKFCDKTFPKKSLLERHYLVHTKQKPFKCEICSKCFNQKSTLKTHILTHNGVQDFRCLLCGLKFSQKINLRVHTFRMHPKRTASVADRLPCPYCPCLFKKLGSLNAHKTKVHAALLPDPTTVEEPPVKSVPEVVQVFEDLVKMSKNVVACDSLEPEVVQPIIACRTQHHLEGKSEDRQHACTICPAAFKKSSHLTQHTRSHYGIKSYRCEICDKTFTTNRSLKIHRISHSSTVPDFRCDQCPASFNLQSSLRRHTAIHDNPDRSYSCPICKRIFKWLQNCKAHIRTSHGKEGAPVSLITAEQSTKLEATQEPHDATLLDLKNLPPNVQIYDINSLTNCLVRIDDQFYELPVQIDTDQLTQDQHIVEIVQEVSTEQMYILPESEIIQEEVLDQSDTPEPPAEPKPKAKDKKLPNVTEQDLFSEGLVNGKKCYSCKACQKPFKKPVDLRRHIRTHTGDRPFKCDRCPKSFTLKAVLQAHRKTHEERREVLFCSEPQCEAKFSSKAALEMHRRIHTGQRPFRCTVCTLTFRTSGHMQAHMVSHERLAAKREQNLLQFGT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -