Basic Information

Insect: Culex pipiens
Gene Symbol: -
Assembly: GCA_016801865.2
Location: NC:9536786-9540158[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 4.6e-05 0.0014 19.5 0.6 2 23 103 124 102 124 0.96

2 17 0.00016 0.0049 17.8 5.2 1 23 130 152 130 152 0.98

3 17 0.037 1.1 10.3 3.6 1 23 158 180 158 180 0.84

4 17 0.38 12 7.1 0.1 2 23 186 208 185 208 0.95

5 17 0.00086 0.026 15.5 5.2 1 23 214 236 214 236 0.98

6 17 0.0015 0.045 14.7 0.4 3 23 241 261 240 261 0.97

7 17 0.008 0.25 12.4 0.4 1 20 268 287 268 289 0.94

8 17 0.44 14 6.9 5.4 1 23 294 317 294 317 0.97

9 17 0.0028 0.085 13.9 0.4 2 23 583 605 582 605 0.92

10 17 0.00011 0.0035 18.2 0.1 1 23 615 637 615 637 0.96

11 17 0.00082 0.025 15.5 2.6 1 23 643 666 643 666 0.96

12 17 0.00038 0.012 16.6 0.8 2 23 672 693 671 693 0.96

13 17 0.024 0.73 10.9 1.6 1 23 699 721 699 721 0.95

14 17 0.00027 0.0083 17.0 1.8 1 23 726 748 726 748 0.97

15 17 5.9e-05 0.0018 19.1 0.1 1 23 754 776 754 776 0.98

16 17 0.047 1.4 10.0 0.3 2 23 783 805 782 805 0.94

17 17 3.1e-05 0.00094 20.0 2.0 1 23 818 840 818 840 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	4.6e-05	0.0014	19.5	0.6	2	23	103	124	102	124	0.96
2	17	0.00016	0.0049	17.8	5.2	1	23	130	152	130	152	0.98
3	17	0.037	1.1	10.3	3.6	1	23	158	180	158	180	0.84
4	17	0.38	12	7.1	0.1	2	23	186	208	185	208	0.95
5	17	0.00086	0.026	15.5	5.2	1	23	214	236	214	236	0.98
6	17	0.0015	0.045	14.7	0.4	3	23	241	261	240	261	0.97
7	17	0.008	0.25	12.4	0.4	1	20	268	287	268	289	0.94
8	17	0.44	14	6.9	5.4	1	23	294	317	294	317	0.97
9	17	0.0028	0.085	13.9	0.4	2	23	583	605	582	605	0.92
10	17	0.00011	0.0035	18.2	0.1	1	23	615	637	615	637	0.96
11	17	0.00082	0.025	15.5	2.6	1	23	643	666	643	666	0.96
12	17	0.00038	0.012	16.6	0.8	2	23	672	693	671	693	0.96
13	17	0.024	0.73	10.9	1.6	1	23	699	721	699	721	0.95
14	17	0.00027	0.0083	17.0	1.8	1	23	726	748	726	748	0.97
15	17	5.9e-05	0.0018	19.1	0.1	1	23	754	776	754	776	0.98
16	17	0.047	1.4	10.0	0.3	2	23	783	805	782	805	0.94
17	17	3.1e-05	0.00094	20.0	2.0	1	23	818	840	818	840	0.94

Sequence Information

Coding Sequence: ATGCCGCGAGGGCGTCCACCTCGGCAAAAATCGGTCCAAGAAGTTGGTGAAAGTGAGAAATTAGTGAAAAGTGAAGAAAAGGGCTCCAAAAAGCGATCTGACAAAAAGCATAGAGCAAAATTGAAGGCATCCCAGTCGAGAGAATTACCGGTTGGTGAAAATGATTCTGCGTCGGTTGCCGATAAGGAAGGCCGGACGTTGGAATCTCGGAAGAGAGGGCGGCCTAGGAAACCGGACTTGGAAGTGGAGGACAGCAGTTTGAAGCAAAAAGATGATGACAAAAATGATTCAGCCAAACCGGTTATTTCTTGCGAAATATGCGGTAAACGGTTCAAATTTCGAGCCACTCTGAAGCAACACGAACAAATCCATTACGGAATAAAAGAATTCGAGTGTGAACAGTGCCATCGGCGCTTCATGCACAAAGGAACGCTCAAAGTCCACATGAGGCTTCATACCGGCGAACTGCCCTATCAATGTCCGCACTGTCCGAAGCGGTTCCGCGGCCAAACCGCCCTGGACTGCCACGTGTTCCGTCACACAAAGCAAGGCACCAAGTGCCCCCAGTGTGATTCGTTGTTTGCCACTCCGTCGATCGTGAAGCAACACATCCGTGAGGTCCACACGACGGAACGGTCGCACACGTGTCAAATCTGCGGAGTCACGTACAAACATCGGAAAACGTTGCGGCTGCACTTGCGGAACCACCAGAAACGAATTTGTCCCGACTGCGGACGGGTGTTTCACAGCGTGTACGCCATGATGACGCACCGGAAGATTCACGCCCAGGATCACTTCCAGTTCCGGTGTGGGTTTTGCGACCGGAAGTTTGAGAAAGAAGACGAGCTGCAGTCGCATGGTAAGCTACGGGGACGGACGTTCCAGTGTGAAATGTGCTGCCATAGCTTCAACAAGGCGGACTACCTGGAGAATCACAACCGACGGAACCACTGGAAGGAGATGGGGCTGGAACAGTTGAAGGTGGCGGCGCCGAAGAATGGCTGGAACCGGAAGGGGGTGCCGAAACCGAAGAAACCGGCAAAGGATTCTGAACCGGTTGATGAGACCGAACTGGTTGATTGGGATGGTGGTCCCGTGCAGGAAACGATAATCCAGACTATTGAAGTGACGGAACCACCTGAAATCATTCAGCAGTACGAGGTGATTCACTATGAAGGACTTCCCGCTGATGCGCAGATCGTTGTGAAAACGATTACAACGGAGATTGAACGAGTTCTACCTCAAGATACCGTTCAGGATGAATTGGGACTAAACGATGAAGTTGAGGATTACGAAGAAgtggaatcgattggtgactaCAATGATCATGACTATTCACTTGCTGGTGAGTTCGCCGAAGGTGAAGCGATGGAGGAACTGAATTGTGAGACGATTGAAGCCAAAAATGAGCCGAAAAGCTTGGAACAGCAGGATTGTGATACGAAACATTTCATCGAGACAAACTATGATGAACTTCCGGGTAAACCCGTTGCAATGAAACAGGAAGCGCGGGAATCCTCGTCGTCCGACAGTGAGGACGAACCTCTTGCAAAACTGGTAACTTCAAAGACAACTGAGGCCATCGTGACTTTAAAGGAGGAAATCAAGCGAGAACCACTGGATCTGAAAGACGAACTTCACAGTTCATCTGAGGACCAGCAATCCTGTGATGGCGAGTCACCAAAACCGAGACGCAAGCGTAAAGCCAACCCGAAGGATACGCGCCAAGGTTCCAAGCGTGAAATGCAGTGTTCCTTCTGTGGAGAATCCTTCAAAGGACGAAAAGCGCTCAAGGAGCACAAGCTAGCGCTTCATCCGGACTTGACTGGCAAGAGTGGGCCTTTCGTTTGCGAGTTGTGCGGTAAAAAGTATGCGACAGCTTCAAGCTTGGTGGTTCACCGCGGTAAGCACGCCGAGTATCAACGGTTCAAGTGCGACGAATGTCCGAAAGCCTTCACCTATCGCTGCTACCTGGATAACCACAAACGAGCAGAGCACCTGCACGAGCGGttaatttgtcaaaagtgtGGCAAGCTTTTCAAGTATCCGCAAGATCTCAAGGTTCACACCAAACAACACGAGGATGAAAAACCCTTCAAGTGTGACATCTGTCCGTCGTCCTTCCGCTTCCCAAGTGCCCTTCGGTGCCACAAGGCTATGCACGTGGCCACGATTTTCTCCTGTGATATTTGCCAAAAGCAGTTCAAGTACGCGAACAGCTTGCGCGTCCACAAAAAACTCCACACGGGGAAAAAACGATTCCAGTGCCAGATCTGCGATCGGGAGTTCAACACGAAGGCTCCGCTGGTTCGACATTTGGCGATTCATTCGATCGAGCGGGAAATGAAGTGCGTTGCGTGTGATAAGATATTTTACAAGAAAATTGACCTCGTGATTCACCAAACGAAGGAGCATCCGAACCACCCGATGATTGGTCGCACGGTGAAAATTCACACATGCCCGGTGTGCGGACAGGAGTTCACTAAGAAAAGTAACCTGAAGTCACACTCGTACATCCACGGCGACGAGTTCAAGTTTGCTTGCGATCTGTGCGAGGATCAAAAGTTTAAGCAGCACGCCGGATTGAGGCACCATTTGACGCACTTCCACAAGCTGGTGATTCGAAAGAGGAAGCCGAAGGAGGAGAAGGGACAAGATTCGGGGGGTTTGGTTGAGTTTGAACAGCCGCTGGTCGACACGACGGTGGCGACAAAGGCCACGCTGATGCCAGGCGTTAGTGTGCTCCACAACGGGGTCCAGTTTATGGTGCAACAGGTGCAGTGTGAatag
Protein Sequence: MPRGRPPRQKSVQEVGESEKLVKSEEKGSKKRSDKKHRAKLKASQSRELPVGENDSASVADKEGRTLESRKRGRPRKPDLEVEDSSLKQKDDDKNDSAKPVISCEICGKRFKFRATLKQHEQIHYGIKEFECEQCHRRFMHKGTLKVHMRLHTGELPYQCPHCPKRFRGQTALDCHVFRHTKQGTKCPQCDSLFATPSIVKQHIREVHTTERSHTCQICGVTYKHRKTLRLHLRNHQKRICPDCGRVFHSVYAMMTHRKIHAQDHFQFRCGFCDRKFEKEDELQSHGKLRGRTFQCEMCCHSFNKADYLENHNRRNHWKEMGLEQLKVAAPKNGWNRKGVPKPKKPAKDSEPVDETELVDWDGGPVQETIIQTIEVTEPPEIIQQYEVIHYEGLPADAQIVVKTITTEIERVLPQDTVQDELGLNDEVEDYEEVESIGDYNDHDYSLAGEFAEGEAMEELNCETIEAKNEPKSLEQQDCDTKHFIETNYDELPGKPVAMKQEARESSSSDSEDEPLAKLVTSKTTEAIVTLKEEIKREPLDLKDELHSSSEDQQSCDGESPKPRRKRKANPKDTRQGSKREMQCSFCGESFKGRKALKEHKLALHPDLTGKSGPFVCELCGKKYATASSLVVHRGKHAEYQRFKCDECPKAFTYRCYLDNHKRAEHLHERLICQKCGKLFKYPQDLKVHTKQHEDEKPFKCDICPSSFRFPSALRCHKAMHVATIFSCDICQKQFKYANSLRVHKKLHTGKKRFQCQICDREFNTKAPLVRHLAIHSIEREMKCVACDKIFYKKIDLVIHQTKEHPNHPMIGRTVKIHTCPVCGQEFTKKSNLKSHSYIHGDEFKFACDLCEDQKFKQHAGLRHHLTHFHKLVIRKRKPKEEKGQDSGGLVEFEQPLVDTTVATKATLMPGVSVLHNGVQFMVQQVQCE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00401926;
90% Identity: iTF_00401926;
80% Identity: -