Basic Information

Insect: Culex pipiens
Gene Symbol: -
Assembly: GCA_016801865.2
Location: NC:21258619-21262778[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.033 1 10.5 3.1 2 23 70 91 69 91 0.95

2 16 0.22 6.6 7.9 2.2 1 21 99 119 99 120 0.92

3 16 0.32 9.8 7.4 1.7 2 23 131 152 130 152 0.85

4 16 0.0002 0.0061 17.5 2.5 1 23 160 183 160 183 0.96

5 16 1.8e-05 0.00056 20.7 1.6 1 23 213 235 213 235 0.98

6 16 1.4e-05 0.00042 21.1 1.2 1 21 243 263 243 265 0.91

7 16 0.0029 0.089 13.8 0.9 1 23 293 315 293 315 0.98

8 16 0.095 2.9 9.0 0.4 2 23 324 347 323 347 0.93

9 16 5.1e-07 1.6e-05 25.6 3.6 1 23 377 399 377 399 0.99

10 16 0.024 0.72 10.9 0.7 1 23 407 429 407 429 0.97

11 16 0.036 1.1 10.4 0.4 1 23 456 478 456 478 0.97

12 16 0.011 0.34 12.0 4.5 1 23 486 508 486 508 0.99

13 16 5.1e-06 0.00016 22.5 0.5 1 23 524 546 524 546 0.98

14 16 0.00027 0.0083 17.0 0.3 1 23 554 576 554 576 0.98

15 16 0.00056 0.017 16.0 2.2 1 23 585 607 585 607 0.99

16 16 0.00072 0.022 15.7 1.7 1 23 615 637 615 637 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.033	1	10.5	3.1	2	23	70	91	69	91	0.95
2	16	0.22	6.6	7.9	2.2	1	21	99	119	99	120	0.92
3	16	0.32	9.8	7.4	1.7	2	23	131	152	130	152	0.85
4	16	0.0002	0.0061	17.5	2.5	1	23	160	183	160	183	0.96
5	16	1.8e-05	0.00056	20.7	1.6	1	23	213	235	213	235	0.98
6	16	1.4e-05	0.00042	21.1	1.2	1	21	243	263	243	265	0.91
7	16	0.0029	0.089	13.8	0.9	1	23	293	315	293	315	0.98
8	16	0.095	2.9	9.0	0.4	2	23	324	347	323	347	0.93
9	16	5.1e-07	1.6e-05	25.6	3.6	1	23	377	399	377	399	0.99
10	16	0.024	0.72	10.9	0.7	1	23	407	429	407	429	0.97
11	16	0.036	1.1	10.4	0.4	1	23	456	478	456	478	0.97
12	16	0.011	0.34	12.0	4.5	1	23	486	508	486	508	0.99
13	16	5.1e-06	0.00016	22.5	0.5	1	23	524	546	524	546	0.98
14	16	0.00027	0.0083	17.0	0.3	1	23	554	576	554	576	0.98
15	16	0.00056	0.017	16.0	2.2	1	23	585	607	585	607	0.99
16	16	0.00072	0.022	15.7	1.7	1	23	615	637	615	637	0.98

Sequence Information

Coding Sequence: ATGGCCGAATCTAAACCATTTTCTGCGGTGGCCAAACAGGAACACGTTGACGTGGAAGATCCAAGTGCATTCTGTTACGAAACCCTAGTAAAGGAAGAACTTATCATCGAGGACGAGCTCGAGCCCTCACCCGAAAAAGATGATGGTCAAGATCAAactgaagttttgcaaaatcaATCTGCAGGCCAGCCGAGCAACACAGAATGGCACTGTGAAAAATGTAACCAATCGTACCCTACCTCTAAATCATTCAGTGCCCACAAGACTCGTCATAAAGCGTTGGAAACTGGCCGGTTCGCGTGTCAACAGTGCGAAAGGCGTTTTCCAGACAACAACGCACAACGCCGTCACAAGTGCAAGGGTAAGGCAACGGGGAATCCCGTATCCTGGGTTTGCGAAGAGTGCAACAGAACATTCCCAAATCGGCATATATTTTATTTGCACAAATACAGGCATAGAGTTGTGAAGGAAGCGAGATACAGGTGTGAACTGTGCGATAAGTGTTTTTCGGACAAAAATGCGCAAACGAAACATGTACAAAATGTGCACAGAGAGAAAAGAAGTATCAAAGCAATACAGTTGAAATCGGAAGATGAACGGGACTCCAAAGCTGAGGAAAAGGACGAAAATGGCCTCTTCAAGTGTCCGGACTGCGATAAGCGCTTCGAGGTCCGCAACAGTTACACTTCACACCTTCGGCAGCACCTTGCTATGAAGCAAGAACGGTACAAGTGCAAGATATGCGAGTTGAGTTTCAGAACAAGCTCCGAGCTCAAGAGGCATGATCGAGCTCATGAGAACCACAAATCCAAATTGTCAAATGACCCGTTTGCCTCGATATGTCCCGAAGCGACCATGAAGGAGGAAAACggcatattcaagtgttcagcgTGTGAGAAGACCTTTGAACAACGGCGTGCGGCTTTGCGTCATCTCATGAGACATGGTTATGTAAAGCGAGACAGGGTTCAGTGCAAATTGTGCCCAATGTTACAGACGTTCGTTAACAAAACGTACCTGGAAAAACATCGAGTGGAACACGAATCTTCGAAGGACGTTTCTGCAAGTGGTTCAAGCAGCGAGAAGGAATCAGATTCGGACGATTTGTCGCAAGATGGAGCCAGCGAATTCAAATGTACCGATTGCAACAAAACATTCCGGGAAAAGCGTCTGTTGAATCGGCATATTCGGAGGCACGAAGCGATCAAAGAGAGCAAATTTCCGTGCAAGCTGTGCGATGTGCGCTGCGGAAGCAAACGAGAGCTGATAACACACGAGGAAATGCACGCTAGGAAGCAACAAACAACGATTGTTTCTACAGAGAAAGTGCCCCCAATAATCTTGGAAAGAAACAACCACACCGTTTACAAGTGTCCTGATTGCGCCTTAATATTCACCAAACAGCGGGTTTATTCCACTCATGCTCTTAGGCACGTTAACGTCAAAAACGGAACCTTCAAGTGTGAAACGTGCGGCGTGTGCTGTCCAACCAGAAGGAACCAGCTGGAACACATACGGAAACATCGAGCGGGAAAGGTTATCGCACCGACGCAGCAGGACAATTTTCCTTTCGAGTGTCCCGAGTGCGGAAAGAAGTTTCCCCTAAGAAAATACCTTATCCAACACGTCAGGCGACATGAGGCCGTGGAAAGTGGCACCTTTCAGTGCAAGATCTGTGCCAAGTTCTTTAGCACTGGTGTAGAACTGGCTAGACACGAGAAGATCCATGAAGGCAAGGACAAGCTGGAAAAGTTTAAGTGTTCCGAGTGTGGCTTCATTTGTGCTTCACGGTCGTCGTTTGTGTGGCATCTTAAGAGGCACGAGGCCATAAGAAGCGGGAAGTTCGAGTGCAAAGTGTGTGGGAAGAAAATGGGATCCAAACATGAACTTGAGGTTCATACTAGAAGGCACCCTGCAAAGTAA
Protein Sequence: MAESKPFSAVAKQEHVDVEDPSAFCYETLVKEELIIEDELEPSPEKDDGQDQTEVLQNQSAGQPSNTEWHCEKCNQSYPTSKSFSAHKTRHKALETGRFACQQCERRFPDNNAQRRHKCKGKATGNPVSWVCEECNRTFPNRHIFYLHKYRHRVVKEARYRCELCDKCFSDKNAQTKHVQNVHREKRSIKAIQLKSEDERDSKAEEKDENGLFKCPDCDKRFEVRNSYTSHLRQHLAMKQERYKCKICELSFRTSSELKRHDRAHENHKSKLSNDPFASICPEATMKEENGIFKCSACEKTFEQRRAALRHLMRHGYVKRDRVQCKLCPMLQTFVNKTYLEKHRVEHESSKDVSASGSSSEKESDSDDLSQDGASEFKCTDCNKTFREKRLLNRHIRRHEAIKESKFPCKLCDVRCGSKRELITHEEMHARKQQTTIVSTEKVPPIILERNNHTVYKCPDCALIFTKQRVYSTHALRHVNVKNGTFKCETCGVCCPTRRNQLEHIRKHRAGKVIAPTQQDNFPFECPECGKKFPLRKYLIQHVRRHEAVESGTFQCKICAKFFSTGVELARHEKIHEGKDKLEKFKCSECGFICASRSSFVWHLKRHEAIRSGKFECKVCGKKMGSKHELEVHTRRHPAK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -