Cpip004724.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Culex pipiens
Gene Symbol
-
Assembly
GCA_016801865.2
Location
NC:136209867-136212406[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.0012 0.037 15.0 0.4 2 23 166 188 165 188 0.95
2 16 0.0037 0.11 13.5 1.9 1 23 191 213 191 213 0.95
3 16 0.0012 0.038 15.0 1.1 3 21 221 239 219 240 0.93
4 16 1 32 5.8 1.7 1 23 260 282 260 282 0.96
5 16 4.4e-05 0.0013 19.5 0.1 3 22 288 307 286 307 0.94
6 16 0.0043 0.13 13.3 0.3 2 23 328 349 327 349 0.97
7 16 2.8e-05 0.00085 20.2 0.0 2 22 354 374 353 374 0.95
8 16 0.00037 0.011 16.6 1.9 3 21 396 414 395 415 0.95
9 16 0.0011 0.035 15.1 0.2 1 23 456 478 456 478 0.98
10 16 0.0016 0.048 14.6 1.1 1 23 485 507 485 507 0.95
11 16 4e-05 0.0012 19.6 0.7 2 23 512 533 511 533 0.98
12 16 0.1 3.1 8.9 1.2 1 23 539 561 539 561 0.96
13 16 0.00062 0.019 15.9 0.3 2 23 568 590 567 590 0.94
14 16 0.00076 0.023 15.6 4.3 1 23 596 618 596 618 0.96
15 16 0.00021 0.0063 17.4 1.0 1 23 624 647 624 647 0.96
16 16 0.00096 0.03 15.3 0.5 1 23 653 675 653 675 0.98

Sequence Information

Coding Sequence
ATGAACCCACCCGTACCGGACACGTCGACCATCTGCCGGGTGTGCATGACGATGGCCAAGGGCGACGGCCACGCGGTCGAGCTGGTCAGCTTGTACACGCTATCGCCCTCGGTTCCGGAGCAGATCAGCCTGCACGAGATGCTGAAGGCGATCTGCGCTCCGGTGTTTGACAAACCGGCGTCCCCGGAAACGATGCCGGAGAATGCCTGTACGGGCTGTCGGAACGACATCATAGCGGCCTTCCGGTTGCACCAGCAGTGCGTCGAGACGGACCGACTGCTCGGGGAGTTGCTGGCGGTGAAGCAGGAGGAGCAGAAGCAGTTTTGTGGCGAGGAGGAGGAAGACATGAAGGTGGATGGCGAGGATCCGCTGATGAGCTGCGAGCGGCGCGAAGTTATCAAGGTTGAGATGCTGGACTTGCTGGAGAAGGTGGATGAGGGGGATAGTTCGGAGGAATCGGACTGCGAAACGCAGGAAGGTGCTAAGGGCAGTATGAAGTGTAAGATTTGTTCAGAGATTTTCAACGACGTCTCCAAGTTGAGCTCGCACATGAAGGATGAACACAGATTATATCTTTGCAAGGAGTGCGGTGAGGTTTGCAAATCGGAACATTCTTTGGCCTATCACATTGTTAAGCACAAAGAGAAGGACATTTCCAATTGCTCCGGTTGTGGGAAACAATTTGCGACCTCACATACCATGCAAAGGCACAAGAAAGGTGGTTTCTGTCCGGGAGAGGGCGAGAGGACGGAAAAGGTAGCCAAGCCTGAACCGACGTTTAGGTGTGACCCGTGTAACGAAACGTTTCAAACGATAGGGTCCTTTAATTACCACAAAACGAAGCATTGTGGTCCAACCGCTTGTGCGGGTTGCCACAAAAGCTTCGCGTCGCCGTCAACGTTGAAGATCCACATCAGATCTGGAGTTTGCAGTGCAGTACAGGACGAACAACCTTCGACGTCCGGGGCTGGTTTGATGATAAAGTGCAACATTTGCGATCTACTGTTCGAAACGGAAAAGGCCTTGAAAGACCACCGAATCAAGCATGCAACGCCAACGGTTTGCCCTGGATGCGACAAGACCTTTGCGTCAAAAATAAGTCTGGCTGCACACATACGAAAGGGATTATGTCCAACGGGGAAGACAAAAATGGATCTGCTGAAGATAAAGGAAGGACCTGTGTTTTGTGACAAGTGCGGCAAGCAGTTTTCGAAGCAATCGAAATTGCAGCTTCACATTAATCATGGCTTCTGTGAAAAAAGTGAAGCATCAGCCCAGGCTCGAACGTGTAAAATTTGCAAAGAGGAACAACAATCCATGTACAAGCTCGGTATCCACATGAAGGAGAAGCATCCAGAAAAGCTGTTTTCGTGCGACATTTGTGGAACAGGTTCGACGACAGAACAAGGCCTGGAAAGGCACAAGAAAATCCACATCGAAGGCAAGTTGGCGTTTTGCTGTCCTGTCTGCCAAGAGGACTTTCCGACGAAACGAATGTTGCGCTCACATCGAATCGCTCATGCCGGCCCGCAGAAATGTAACGTTTGCGATAAAGTCGTAACGTCCAAGAGCGCCATGAGGTCCCACATGCTGCGGCATACCGGCGAGAGGAAATTTTTCTGCGACCACTGCCCCATGCGGTTCTTCACAGCGGTCGAAAAAGCGCAGCACCTGGTCACGCACACCAGAGAACAGAACTGGATTTGTGACACGTGCGGTTCCAGATTCACCAAGAAGACGTCACTGCAAATCCACATCAAAGAGATTCACGAACGGCGGCGCGACCATGCCTGCACGCTGTGCAATTACGTCTGCGCGAAAACTTCCCAGCTAAAGCGTCACATGCTCACACACACGGGAGAAaaacccttcaaatgtacgcactGCGAGCAGGCTTACGCGCAAAGCAACGATCTGACCAAGCACGTGGCTCGGGTGCACTCGGACGGGAAGGCCTACCCGTGCGATCGGTGCAACGAGTCGTTCCGGCTGTTGCTGGAGCTTAGGCAGCACTACCGGGTGCACGTGAAGGAAGGAGAGGATGACCCACAGGGTGGGACGGTCAGGTTTACCACCATGGCGGTGCTGAGCCGGCGGCTGGACGTGGAacgacaacagcagcagcagcagatggaGGAGGGCGGTTCGAATTAA
Protein Sequence
MNPPVPDTSTICRVCMTMAKGDGHAVELVSLYTLSPSVPEQISLHEMLKAICAPVFDKPASPETMPENACTGCRNDIIAAFRLHQQCVETDRLLGELLAVKQEEQKQFCGEEEEDMKVDGEDPLMSCERREVIKVEMLDLLEKVDEGDSSEESDCETQEGAKGSMKCKICSEIFNDVSKLSSHMKDEHRLYLCKECGEVCKSEHSLAYHIVKHKEKDISNCSGCGKQFATSHTMQRHKKGGFCPGEGERTEKVAKPEPTFRCDPCNETFQTIGSFNYHKTKHCGPTACAGCHKSFASPSTLKIHIRSGVCSAVQDEQPSTSGAGLMIKCNICDLLFETEKALKDHRIKHATPTVCPGCDKTFASKISLAAHIRKGLCPTGKTKMDLLKIKEGPVFCDKCGKQFSKQSKLQLHINHGFCEKSEASAQARTCKICKEEQQSMYKLGIHMKEKHPEKLFSCDICGTGSTTEQGLERHKKIHIEGKLAFCCPVCQEDFPTKRMLRSHRIAHAGPQKCNVCDKVVTSKSAMRSHMLRHTGERKFFCDHCPMRFFTAVEKAQHLVTHTREQNWICDTCGSRFTKKTSLQIHIKEIHERRRDHACTLCNYVCAKTSQLKRHMLTHTGEKPFKCTHCEQAYAQSNDLTKHVARVHSDGKAYPCDRCNESFRLLLELRQHYRVHVKEGEDDPQGGTVRFTTMAVLSRRLDVERQQQQQQMEEGGSN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00401925;
90% Identity
iTF_00401925;
80% Identity
-