Basic Information

Insect: Culex pipiens
Gene Symbol: -
Assembly: GCA_016801865.2
Location: NC:133617938-133640835[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.0004 0.012 16.5 1.0 1 23 190 212 190 212 0.99

2 16 6.7e-05 0.0021 18.9 0.5 1 23 218 241 218 241 0.94

3 16 0.00025 0.0075 17.2 0.5 2 23 249 271 248 271 0.94

4 16 1e-05 0.00031 21.5 2.0 1 23 283 305 283 305 0.96

5 16 0.00055 0.017 16.1 5.3 1 23 312 334 312 334 0.98

6 16 0.0022 0.068 14.2 0.1 2 23 370 392 369 392 0.95

7 16 5.5e-06 0.00017 22.4 2.6 1 23 398 420 398 420 0.98

8 16 0.00012 0.0038 18.1 1.9 1 23 903 925 903 925 0.98

9 16 0.00079 0.024 15.6 1.2 3 23 933 954 932 954 0.96

10 16 0.029 0.9 10.6 2.0 1 23 961 985 961 985 0.97

11 16 0.0001 0.0032 18.3 0.5 2 23 998 1019 997 1019 0.93

12 16 0.0021 0.064 14.2 2.7 1 23 1025 1047 1025 1047 0.98

13 16 0.0097 0.3 12.2 3.7 1 23 1053 1075 1053 1075 0.97

14 16 0.00021 0.0065 17.4 0.5 1 23 1081 1104 1081 1104 0.98

15 16 0.00026 0.0081 17.1 1.6 1 23 1110 1132 1110 1132 0.98

16 16 1.4e-06 4.2e-05 24.3 1.4 1 23 1138 1160 1138 1160 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.0004	0.012	16.5	1.0	1	23	190	212	190	212	0.99
2	16	6.7e-05	0.0021	18.9	0.5	1	23	218	241	218	241	0.94
3	16	0.00025	0.0075	17.2	0.5	2	23	249	271	248	271	0.94
4	16	1e-05	0.00031	21.5	2.0	1	23	283	305	283	305	0.96
5	16	0.00055	0.017	16.1	5.3	1	23	312	334	312	334	0.98
6	16	0.0022	0.068	14.2	0.1	2	23	370	392	369	392	0.95
7	16	5.5e-06	0.00017	22.4	2.6	1	23	398	420	398	420	0.98
8	16	0.00012	0.0038	18.1	1.9	1	23	903	925	903	925	0.98
9	16	0.00079	0.024	15.6	1.2	3	23	933	954	932	954	0.96
10	16	0.029	0.9	10.6	2.0	1	23	961	985	961	985	0.97
11	16	0.0001	0.0032	18.3	0.5	2	23	998	1019	997	1019	0.93
12	16	0.0021	0.064	14.2	2.7	1	23	1025	1047	1025	1047	0.98
13	16	0.0097	0.3	12.2	3.7	1	23	1053	1075	1053	1075	0.97
14	16	0.00021	0.0065	17.4	0.5	1	23	1081	1104	1081	1104	0.98
15	16	0.00026	0.0081	17.1	1.6	1	23	1110	1132	1110	1132	0.98
16	16	1.4e-06	4.2e-05	24.3	1.4	1	23	1138	1160	1138	1160	0.98

Sequence Information

Coding Sequence: ATGCGAATCTGCCGCGTTTGTGGCGAATCGTTGCTAGCGCAAAGCCAGCCCCAGAGCTTGGACAGGTACACGGGCATTTACTTCCACCTGACCGCGATCCAGCTGGCGGACCACGAAGATCCCGCCCAGTGCAAGATCTGCGGGCTGTGCATCGAGAAGCTGGAGGACTTTGACCGCTTCCGGAAGGTGTGCCTGGAGGTGCACTGGCGGCTGAGCAAAGTGAAATTTGAACCGATAGATGAGGATGCGCACGAGGAGACGGTTCAGGTGGAGTGCAAGACCGAATTTCAGGAAGATTTTGAGCTGATCCGGAGTGTGATTAAGGAGAAGAACGAGGTGGAATCCAGCGATGAAGAGGAGGACGATGATGGCAATTTGGACGGGAATGACTCAGACTCGGACGATGAAGACGACGATTACATGGATGATGATATCGTTGCAGACGAACTTCCGTTGTTTCCCAAAACAGAGTCCGGCGATTCTGACTCGGAGGATGAGCCCAAGCCTAAGAAGAAACGAGCCAAGTGGGGCAGTTTGAAAAAGGAGCGCAAGGAACCAATGCAGGTTTACGAGTGCGACCAATGTCCGAAGAAGTTCCGCGTCCTGATGCGATTGAACGCCCACAAACGAACCCACGAAGGTTTGAAACCGTTCGTTTGCGAGCTCTGCGGAAAGGACTTTGCCAAGTGGAACAACCTGAAAACGCATCGCATCCAGAAGCACTCGGACAACAAAATCGCCATGCCGTGCATGGAGTGTGGCCAAACGTTCGCTACCAAGCAGGGCTTGAAGCGACACCGGGAGCGCAACCACGACCCCAACTACGTCGCACCGGAGCCGATTTCGTTCATGTGTGACACGTGCGGCAAGACGTTCACCACCAACGGAACGCTCAAGAAGCACAAGTACATCCACACGCCCAACGAGATGCCGTTTGTGTGTCAAATCTGCGACAAAAAGTTCCCCACCAAGCACAAATTGCACGAGCACACGATGCGACACGAGGGCGTAAAGAATCACACTTGCCCGTGCTGCGGCTTGCGGAAAACGACCATGCATGAGCTGAGGACGCACATGAAGAACGTACACTCCAAGTCGCGGACGATTCCGTGCGATTTCTGCACCACGATGTTTGCCAACATTGGAAACCTCAACCGCCACGTCAAGATTGTCCACCTGGGCGTAAAGCCGTACAACTGCACGGTTTGCGATCGCGCATTCGGCAAATCCGACCACCTCAAACGCCACATGAAGAGTCACAATCGAACTGGGGGGCCCAGCGGAGGAGGAGTAGCTACGGAAGCAGACGATGATCACATTCCAGTCGTGGACGCGGCGGCCACGTTGCCATCCCAACCGGCGGCCCACACTCCGATGGCGCCGATGCTGGCGCAGATGTTCCAGCGTCGACTCGTCCGTAAACCCCAGCAGATTCTCCAACACCCGGCTGCTCAGCTGATTCGACGACGTCTTGATCTCCTTCTCGCGGATCTGCTCGTACACGTTGCAGGCCATCGTGCTCCGCTCGTCCGCGTCCTCCAGCCCGTTCATCGCTTCCAGAATCTCGACGAAATAGTTGTACTCGTCCTGCTCCAGCTCAGCCCCCCTCCCGAAGCTGTTCTTCCGGCCGAAACCCTTCGCGTTCTGCAGGAACCGCTTGCCGGCGGATTTCTTCTTTTTGTTGCGATTCTTGAAGTGGTTCGAGCCACGTTCCGTCTGCGGCTCAATTGCGTCCTGGAGGAGTACCACTACCTCGCGGAACCGTTCGACCGTGGCCAGCTGAAGGAAATGGCCAGCGCGGTCCCGCCCAAGGATTGCCGCGCCGACGAGGAGTTTCGCGAAAGTTTGACGTCGCGCCAGCGGGAAGTGCTCGACGAGGTGCAGGAGCTGGTGCGCGATCGGATCGGGCGGCGGGCGCGCCAGGAATCGGTCAAGGACGTGGTCGGCATGCAGGTGGACGTGAGCGCCCAGTACCGGGTGACCTGCGACAGCTACAAGGAGATGCTGGGCAAAATAAAGATCTACGAACTGGACGTCATGCTCGAGGACCGGCACATCGAGGAGCTGCGCCTGGACAGTTTGGAGGTGAAGTACACCATGACCGATACCCTGTCAAAGGTTGCACTGCTCCAGGAATCAGCTCTTCCGGAAGTCAATACAAGAAGAATAGTGCTCAACAAGATGGACATGTGCCGGGCCTGCGGGGAGTTCCCCGACGGGACCAACCAGCTGTCGGAGTACTTGGAAAAGTATTCCGACATTTACTTCAATCTGACATCGATTAAGCTGCCTCCAGGGGAAGATTCGGACCGGCAGCGGATCTGCGAGGGATGTCACCTGAAGCTGTTGGAGTACAACCGATTCCGGACGGTTTGCTTGCAGGTTCATTACAAGCTATCGGCTATTAAAAAGGAAATTGAACCAGACCAGGGAGATGTCGTGGACTTGGAGTGCAAGCCAAACGTCGACGCGCTGAAGATTGAGCAGTTTGATTTCTCTGACAACGACTTGGCGGAAGATGACGGACGGAATGCGGGAAAAGAAGAAGAGCACTCCGAGGATGACAATTCGTTCCAGGGAGATTCCAGCTCGAATTCCAGCAGCGAGAGTGAATCGGAGGACGAACGACCGATCGCCAGTCGGCGGAAAAATAAGCAGAAGCAGAGCGCCAAGTCCAAACCGGTGGACGACAGCAAGGAGCAGATTTATCCCTGTACGGAGTGTAACAAAAAGTTCCGCAGCGAGACGCGCTTCCAGGGCCACATGCGGATGCACGAGGGTCTCAAACCGGCACTCTGCACGACCTGCGGCAAATCGTTCGCCAAGTACAACAGTCTGAAgctgcacatcaaccagaagcACTCGGAGAACAAGGTCAAGTATCCGTGCGACTTTCCGGGCTGCGAGCACGTCTACTCGACGAAGCAAACGATGCAGCAGCACCGGAAGAAGCACGACCCGAACTACGTGACGCCGGAGCAGAAGCGGTCCGTTTGCGATCAGTGCGGCAAGACGTTCTCGACGACCGGGGCGCTAAAGAAACATAGTTACATTCATACTGGCGATATGCCTTTCCAGTGCACAGTCTGTAATAAAAAGCTTCCAACGGCTCACAAGCTGAAGGAACACACAATGAGACATGAGgGAGTCAAAAATCACGTTTGCCCGTACTGTGGAATGAAGAAGACGACTCGTCACGAGCTAAAGGTTCACATGAACTATCACACCCGTGAGAAGCAATTCACGTGTCACGTGTGCGCACAAGTCTTTTCCAACATTGGCAACATGAGCCGCCACATCCGCATCGTCCACTGTGGCATCAAGAAGTACTCGTGCACGTACTGCGAGCGCTCCTTTGGCAAGGCCGAAACGCTCAAGCATCACGTCATGATCCACACGGGAGAGAAACCGCACGAGTGCAAGATATGCGGCCGGCGCTTCATCCAGTCGGTGGCGCTGCAAACGCACATGAAAACGCACCGGAAgcatcaacagcagcaacagcaatcgATGCAGCAACAGCAGTCGCCTTCGGTTGGGCCGCAAATTGCACCCCAGCTGGCGCTTgatccgcagcagcagcagcagcaaactcAGCTTCACCATCCGTCGATGATGATGCATTCGCCACCGCCGCAGATTCCGCTTGGGGCGCCCCAGCAGCAGCATTTACAGTGA
Protein Sequence: MRICRVCGESLLAQSQPQSLDRYTGIYFHLTAIQLADHEDPAQCKICGLCIEKLEDFDRFRKVCLEVHWRLSKVKFEPIDEDAHEETVQVECKTEFQEDFELIRSVIKEKNEVESSDEEEDDDGNLDGNDSDSDDEDDDYMDDDIVADELPLFPKTESGDSDSEDEPKPKKKRAKWGSLKKERKEPMQVYECDQCPKKFRVLMRLNAHKRTHEGLKPFVCELCGKDFAKWNNLKTHRIQKHSDNKIAMPCMECGQTFATKQGLKRHRERNHDPNYVAPEPISFMCDTCGKTFTTNGTLKKHKYIHTPNEMPFVCQICDKKFPTKHKLHEHTMRHEGVKNHTCPCCGLRKTTMHELRTHMKNVHSKSRTIPCDFCTTMFANIGNLNRHVKIVHLGVKPYNCTVCDRAFGKSDHLKRHMKSHNRTGGPSGGGVATEADDDHIPVVDAAATLPSQPAAHTPMAPMLAQMFQRRLVRKPQQILQHPAAQLIRRRLDLLLADLLVHVAGHRAPLVRVLQPVHRFQNLDEIVVLVLLQLSPPPEAVLPAETLRVLQEPLAGGFLLFVAILEVVRATFRLRLNCVLEEYHYLAEPFDRGQLKEMASAVPPKDCRADEEFRESLTSRQREVLDEVQELVRDRIGRRARQESVKDVVGMQVDVSAQYRVTCDSYKEMLGKIKIYELDVMLEDRHIEELRLDSLEVKYTMTDTLSKVALLQESALPEVNTRRIVLNKMDMCRACGEFPDGTNQLSEYLEKYSDIYFNLTSIKLPPGEDSDRQRICEGCHLKLLEYNRFRTVCLQVHYKLSAIKKEIEPDQGDVVDLECKPNVDALKIEQFDFSDNDLAEDDGRNAGKEEEHSEDDNSFQGDSSSNSSSESESEDERPIASRRKNKQKQSAKSKPVDDSKEQIYPCTECNKKFRSETRFQGHMRMHEGLKPALCTTCGKSFAKYNSLKLHINQKHSENKVKYPCDFPGCEHVYSTKQTMQQHRKKHDPNYVTPEQKRSVCDQCGKTFSTTGALKKHSYIHTGDMPFQCTVCNKKLPTAHKLKEHTMRHEGVKNHVCPYCGMKKTTRHELKVHMNYHTREKQFTCHVCAQVFSNIGNMSRHIRIVHCGIKKYSCTYCERSFGKAETLKHHVMIHTGEKPHECKICGRRFIQSVALQTHMKTHRKHQQQQQQSMQQQQSPSVGPQIAPQLALDPQQQQQQTQLHHPSMMMHSPPPQIPLGAPQQQHLQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -