Basic Information

Insect: Culex pipiens
Gene Symbol: -
Assembly: GCA_016801865.2
Location: NW:10952-14677[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 24 0.00091 0.028 15.4 0.3 2 23 50 71 49 71 0.97

2 24 0.00022 0.0069 17.3 0.6 1 23 80 103 80 103 0.97

3 24 0.0015 0.046 14.7 0.2 2 23 113 135 112 135 0.94

4 24 3.9e-05 0.0012 19.7 0.6 1 23 142 164 142 164 0.99

5 24 0.0013 0.041 14.9 0.1 1 20 169 188 169 190 0.92

6 24 0.01 0.31 12.1 1.4 2 21 197 216 196 217 0.92

7 24 0.004 0.12 13.4 0.1 1 23 225 247 225 247 0.96

8 24 0.0046 0.14 13.2 0.7 1 23 251 274 251 274 0.97

9 24 0.00054 0.016 16.1 0.8 1 23 346 369 346 369 0.96

10 24 1.7e-05 0.00053 20.8 0.9 2 23 577 599 576 599 0.94

11 24 0.021 0.65 11.1 2.2 1 23 620 643 620 643 0.94

12 24 0.0091 0.28 12.2 2.6 2 23 657 679 657 679 0.94

13 24 0.0077 0.24 12.5 2.5 1 23 724 746 724 746 0.98

14 24 0.015 0.47 11.5 3.3 1 23 752 775 752 775 0.96

15 24 0.016 0.5 11.4 0.3 2 23 799 821 798 821 0.93

16 24 0.004 0.12 13.4 1.4 1 23 842 865 842 865 0.95

17 24 0.0078 0.24 12.4 3.9 1 23 882 905 882 905 0.96

18 24 5.8 1.8e+02 3.4 0.2 2 21 916 935 915 936 0.92

19 24 0.0099 0.3 12.1 1.6 1 23 947 969 947 969 0.98

20 24 0.011 0.34 12.0 0.8 1 23 975 998 975 998 0.97

21 24 0.00049 0.015 16.2 1.5 1 23 1005 1027 1005 1027 0.96

22 24 0.0065 0.2 12.7 7.9 1 23 1032 1055 1032 1055 0.91

23 24 8.3e-05 0.0025 18.7 0.4 2 23 1070 1091 1069 1091 0.97

24 24 0.0011 0.033 15.1 0.2 1 23 1097 1121 1097 1121 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	24	0.00091	0.028	15.4	0.3	2	23	50	71	49	71	0.97
2	24	0.00022	0.0069	17.3	0.6	1	23	80	103	80	103	0.97
3	24	0.0015	0.046	14.7	0.2	2	23	113	135	112	135	0.94
4	24	3.9e-05	0.0012	19.7	0.6	1	23	142	164	142	164	0.99
5	24	0.0013	0.041	14.9	0.1	1	20	169	188	169	190	0.92
6	24	0.01	0.31	12.1	1.4	2	21	197	216	196	217	0.92
7	24	0.004	0.12	13.4	0.1	1	23	225	247	225	247	0.96
8	24	0.0046	0.14	13.2	0.7	1	23	251	274	251	274	0.97
9	24	0.00054	0.016	16.1	0.8	1	23	346	369	346	369	0.96
10	24	1.7e-05	0.00053	20.8	0.9	2	23	577	599	576	599	0.94
11	24	0.021	0.65	11.1	2.2	1	23	620	643	620	643	0.94
12	24	0.0091	0.28	12.2	2.6	2	23	657	679	657	679	0.94
13	24	0.0077	0.24	12.5	2.5	1	23	724	746	724	746	0.98
14	24	0.015	0.47	11.5	3.3	1	23	752	775	752	775	0.96
15	24	0.016	0.5	11.4	0.3	2	23	799	821	798	821	0.93
16	24	0.004	0.12	13.4	1.4	1	23	842	865	842	865	0.95
17	24	0.0078	0.24	12.4	3.9	1	23	882	905	882	905	0.96
18	24	5.8	1.8e+02	3.4	0.2	2	21	916	935	915	936	0.92
19	24	0.0099	0.3	12.1	1.6	1	23	947	969	947	969	0.98
20	24	0.011	0.34	12.0	0.8	1	23	975	998	975	998	0.97
21	24	0.00049	0.015	16.2	1.5	1	23	1005	1027	1005	1027	0.96
22	24	0.0065	0.2	12.7	7.9	1	23	1032	1055	1032	1055	0.91
23	24	8.3e-05	0.0025	18.7	0.4	2	23	1070	1091	1069	1091	0.97
24	24	0.0011	0.033	15.1	0.2	1	23	1097	1121	1097	1121	0.97

Sequence Information

Coding Sequence: ATGGAAGCGGACAACTCAGGTTCAGAACTCTTCGAAAAAGTGAACGAAACGCTTGAAATAAACGAATCAAAGGCGGACTTCAACCAAGAACCGGAAGACGACGATTTTCTTCCACCGGAACCCAAACCCCCTAAAAAGCACCCCTTACAATGCGAAGTCTGCGACAAAATTCTCACGACCAAGCAGTCCCTCAAACTCCACGCGCTCACTCACGTAGATCCGGCCAACCGGAAGACCTTCCGGTGCGAGATCTGCGAGACCACGTTCAAGTCCCAGCCCGGCCTAAATTACCACCTGGAAACGAAGCACAACCCGGACTTTGAGCGCAAAAAGTTGCCCTGTCCGACGTGCGGGCGGAATTTCAAAAGCAGTGAAGGTCGGAAGATCCACATGACCATTCAGCATGGGGCCGGCGGACCAATCTTCAAGTGCAAGGAATGTCCGATGGTATTCGCGCGGAGGCCCCACCTCGACCTTCACATGGCAACTCATGGCGCGGGCCAGCACGTTTGCACGATCTGCGGGAAGTCGTACGCCAGGCTGAAGGACCTGTCCCTGCACGAGGCCACCTGCGGCGTGAAGGATCTGTGCTGCGCTGTCTGTGGCAAGCAGTTCCGGAAGGAAAAAGCCCTCGAAAATCACCGGAAAAAGTGTCGTCAAGAATGTCGGAACTTTCGCTGTTTGACCTGCGGCCAGGGATTCGCCACGGAGCAAGCGTTAAAGACGCACGAGGCGGTCCACCGGAGGACGTTCCGATGTTCGGAATGCTCGCAGACTTTCGTCACCGTGCTGGCCCTTCGGAACCACGAGCAGACCAAGCATTGGGAGCCGAATGGGTTTGAGGCTGGTGTCGGTGAGAAGCGGGGTCGTCCGAGGAAGAGCGGCTCCGGCGGTGGGGACGGCAAGGTTCGCATGAGACGCAGCAAATATGACCTGTTTATTGGACTGGAACATTTGGCCGATCCATCGACGCTGATCGAGGAAGAGAAACCGGTTAAGGATGAACTGAAGCCGGCCGATCTCGATCCAAAGAGGTTTCCGTGCGAGCATTGTCCGCTGAAGTTTGCTACCTCGCAAGCATTGCAGAATCACGCGCAGAGACGTCACTGGGAGGTTTTGGGTCTTGCGGCACCAGCTCCCGAGAAACGAGGACGCAAGAGGACGCGTCCGTTGGTGCGAGTTTCGAAGAAGCGTCCGTTGGAGCCAGTTTCGAGGAAGAGAGTTCGCAGACCGCGCAAGTTGGTCAACTATGTTGAGCTTATGGATTTGCCGGAAATGGTTGAATGTGACGCTGTGAAGGAGGAAGATGGTCCGATGAAGTCCGAATTAGTAGAGAACGTTGTCATTCCTGCAAACGTTGCTTACGCTGAGGAGAAAAGTGCGCCGATCGAACAAGTTGAAGAATCCGATATTTTTGCAACGAACGAAGTTATCATCAAGGAGGAGATCGTTGGGTTTGAGGACTACGAATTTGATTACTTTGAAAATGACTCGGCCGGCGGCGACGAACCCGTTGATGAGCTCACGTTTGAGAACATTGTTGCGGACCTTGAACTGGCTTGCGAGCCAACGAACGATGAAGTTGACACTCTCGCCGTAGAACCAGAGCTGGAGAACAACGTGTCGGAGCAACCACACATTTTCAAAGAACTCGTCATCAGATTGGAGAAGCTGGATTATTCCGCCCTCGTGGAGTCCAGTAACGGCAAGAAACATTTCAATCGGAAGGAATGCGAACATTGTGGAAAAGCGTTTGTACGTCAATACGATTTAGCGAAGCACCGGGTCAGGGAACACGGAAGTACGGAAACGCCAACGAGAACCAAACCACCACCGAAGATGACACTGCCACCAAGCTACCGCTGCGAGGAATGCGAGAAATCGTACCAGTTTGAGCATTACCTTAAGGCGCACAATGAAAAAGTGCACGGCATCACGGAAGAACCTGGTGACGGTGCTAATATTCGAACTTGTAAGCATTGCGGACAGAAGTTGAAATCCTGGCCAAGTCTGGTgaaacatttgaagtttttccaCGCAGAAAGTGTCGACGAATCGCAGTTTGTTAAATGTCCGTCGTGTCCTGCAAAGTTTCTTAATCAGGAAGACTTGGACGGGCACGTCTGCACCAAGAGAGACGTTTGCGAAAGGGAACCAAGGGAGCGTTCCTTCAAGTGTGATCTGTGCCGTAAAACGTACTCTTTCCTCCTTCATTTGGAAGCGCACTATTCCGTGCATCCAGAATACCAGAACTTCAAATGTGACCACTGTTCGAACGGATTCTACAACGAAAGGGAGCTCAACAAGCACAAGAAGAACGCGCACGAACCGAAACCTGCGGTGACGAAGATTCGCCCCTTCAAATCCAAGTACAAAAATCCATTTCCTAGGACGGAATGCGAACAATGTGGACAAACGTTTGCCTACCGATATCGGCTAGCCCTGCACCGGGTCAAGGAACACGGAAGTACGGAAATACCAGTGGCAAACAGACCAGCAGCAAGTGCGACACTTCCACGAAACTTCCCTTGTGACCAGTGCGATAAATCATACCATCTTCAGACTAATCTCACGATTCACAAAGCCAAGGTTCATGGCGATGGAGAAGCCCCACCAAAGTATCATCCAACCAAAATCTTGAAGCACACCTGCAAGCACTGTAAGAAACAATTTACAGCCTGGGGCGCTCTGATCTACCATCGAAAGTACATCCACGGAGAAAGCATCGAAAAGACGCAATTTGTGCAATGTCCGTCGTGTCGTTTGAAATTCGCAACCGACGAGGAAATGGCGGAGCATCTTTGCCTCAAGGGAGTCATTCGCCCTAGGGAACGTCCCTTCAAGTGCAACCTGTGCGATAAATCTTATTTCGCGAAACCTCATCTGGAGGGCCACTATTCCGTTCATTCGGAGTACCACAACTTCAAGTGTGATCAATGCTCGAAGGGTTTCTTTGCCGAATCCGAGCTCGTAAGCCACAAGAAGAAAGCACACATTGCAAAAGAGCTGTACTACGCGTGCGAGACCTGCAATCAGCTGTTCAAAAGCCAACAAAACTTGAAGCGACACCGGGAGCTTCACATGGGCCGCGAGTACTGCTGCGAGCATTGtggcaaaaagttcaaaatgcgAACAAACCTCAAATCGCACGTGTTCCACGTGCACGCCGAGTACGCTAGCGAGGCCGCCCGAGCCGCTCAAGCGATCCCATGCACAGTCTGCGGTAAAACGCTGAGAGGAACAAGCGCGTTTAAGCAGCACATGCGAACTCACAACAACGATCGACGGTACAAATGTTCCTTTCCGTCCTGTGGCAAAACCTTCATCGCGAGTGGCAGTTTGAAAGTGCACGTGCAAAGTCACACGAAGGACTACAAGTACAAGTGCAAGTTCTGCGAGTACGGGACCGTTTTCCGGAAAAGAATTGTGCTGCACGAGCAGCGGGAGCACAACCATAACCGGTTCGCGGGAGTGAACGATTCGCAATAG
Protein Sequence: MEADNSGSELFEKVNETLEINESKADFNQEPEDDDFLPPEPKPPKKHPLQCEVCDKILTTKQSLKLHALTHVDPANRKTFRCEICETTFKSQPGLNYHLETKHNPDFERKKLPCPTCGRNFKSSEGRKIHMTIQHGAGGPIFKCKECPMVFARRPHLDLHMATHGAGQHVCTICGKSYARLKDLSLHEATCGVKDLCCAVCGKQFRKEKALENHRKKCRQECRNFRCLTCGQGFATEQALKTHEAVHRRTFRCSECSQTFVTVLALRNHEQTKHWEPNGFEAGVGEKRGRPRKSGSGGGDGKVRMRRSKYDLFIGLEHLADPSTLIEEEKPVKDELKPADLDPKRFPCEHCPLKFATSQALQNHAQRRHWEVLGLAAPAPEKRGRKRTRPLVRVSKKRPLEPVSRKRVRRPRKLVNYVELMDLPEMVECDAVKEEDGPMKSELVENVVIPANVAYAEEKSAPIEQVEESDIFATNEVIIKEEIVGFEDYEFDYFENDSAGGDEPVDELTFENIVADLELACEPTNDEVDTLAVEPELENNVSEQPHIFKELVIRLEKLDYSALVESSNGKKHFNRKECEHCGKAFVRQYDLAKHRVREHGSTETPTRTKPPPKMTLPPSYRCEECEKSYQFEHYLKAHNEKVHGITEEPGDGANIRTCKHCGQKLKSWPSLVKHLKFFHAESVDESQFVKCPSCPAKFLNQEDLDGHVCTKRDVCEREPRERSFKCDLCRKTYSFLLHLEAHYSVHPEYQNFKCDHCSNGFYNERELNKHKKNAHEPKPAVTKIRPFKSKYKNPFPRTECEQCGQTFAYRYRLALHRVKEHGSTEIPVANRPAASATLPRNFPCDQCDKSYHLQTNLTIHKAKVHGDGEAPPKYHPTKILKHTCKHCKKQFTAWGALIYHRKYIHGESIEKTQFVQCPSCRLKFATDEEMAEHLCLKGVIRPRERPFKCNLCDKSYFAKPHLEGHYSVHSEYHNFKCDQCSKGFFAESELVSHKKKAHIAKELYYACETCNQLFKSQQNLKRHRELHMGREYCCEHCGKKFKMRTNLKSHVFHVHAEYASEAARAAQAIPCTVCGKTLRGTSAFKQHMRTHNNDRRYKCSFPSCGKTFIASGSLKVHVQSHTKDYKYKCKFCEYGTVFRKRIVLHEQREHNHNRFAGVNDSQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00401910;
90% Identity: iTF_00401910;
80% Identity: -