Cpip000751.1
Basic Information
- Insect
- Culex pipiens
- Gene Symbol
- -
- Assembly
- GCA_016801865.2
- Location
- NC:20652931-20677029[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 28 0.013 0.39 11.8 0.3 2 23 258 280 258 280 0.93 2 28 0.057 1.8 9.7 0.6 2 23 318 340 317 340 0.96 3 28 0.0024 0.075 14.0 5.2 2 23 355 377 354 377 0.95 4 28 0.0081 0.25 12.4 0.7 3 23 386 407 384 407 0.93 5 28 0.0016 0.049 14.6 1.1 1 23 413 436 413 436 0.95 6 28 0.036 1.1 10.4 2.8 1 23 442 465 442 465 0.95 7 28 5.3 1.6e+02 3.5 1.1 2 22 505 525 504 527 0.75 8 28 0.0041 0.12 13.3 1.0 2 23 534 556 533 556 0.93 9 28 1.5e-05 0.00046 21.0 0.8 2 23 575 597 574 597 0.93 10 28 0.0019 0.06 14.3 1.3 1 21 603 623 603 626 0.96 11 28 0.0059 0.18 12.8 0.6 1 20 632 651 632 653 0.93 12 28 1.8 56 5.0 1.1 2 23 1427 1449 1426 1449 0.94 13 28 0.0059 0.18 12.8 2.1 2 23 1817 1838 1816 1838 0.96 14 28 0.003 0.093 13.7 2.3 1 23 1844 1867 1844 1867 0.94 15 28 0.055 1.7 9.8 0.8 1 23 1873 1896 1873 1896 0.97 16 28 0.11 3.2 8.9 0.4 1 23 1907 1930 1907 1930 0.94 17 28 0.00014 0.0043 18.0 0.3 1 23 1970 1993 1970 1993 0.96 18 28 0.024 0.73 10.9 4.4 1 23 2002 2024 2002 2024 0.96 19 28 1.7e-05 0.00051 20.9 0.5 1 23 2030 2053 2030 2053 0.97 20 28 0.0052 0.16 13.0 1.4 1 23 2059 2082 2059 2082 0.96 21 28 0.15 4.7 8.4 0.2 3 23 2094 2115 2093 2115 0.97 22 28 8.8e-05 0.0027 18.6 0.5 1 23 2121 2143 2121 2143 0.96 23 28 3.7e-05 0.0011 19.8 2.6 1 23 2149 2172 2149 2172 0.96 24 28 0.0024 0.072 14.1 0.6 1 23 2178 2201 2178 2201 0.93 25 28 0.00024 0.0072 17.2 0.1 1 23 2210 2233 2210 2233 0.97 26 28 2.7e-06 8.2e-05 23.4 0.2 2 23 2238 2259 2237 2259 0.97 27 28 0.0024 0.073 14.1 1.4 3 23 2267 2288 2265 2288 0.96 28 28 0.0087 0.27 12.3 0.3 3 20 2296 2313 2294 2315 0.95
Sequence Information
- Coding Sequence
- ATGGTTTGCTGCGTTCCGGGTTGCCTTCCGGCGGACACGAGCGGCGGCCTCGTGCGGGTCGTCAAATTTCCCACCGAGGACGATTTGCGTCGCCGCTGGCTGCAGGCCGTCGAGATCGGAAGTGGAACGGCGCTCGACGATGACGACGCCGACTACCAGCTCTGCACGGGCCACTTTGAGTGGGCCGGGGACGAGcaggagtaccgggaaccgacGGTGTTTGGGGGAGGgaatgtTGCGAGCTGCAGGTTGTGCCATCAGTTCCTGCCGGTGAGCCGGATGGTGCCGTCGGTTGGGGGTGGGACGTTTGCCGATATGGCACTCGATACGATGGTGGCGCTGGTGCTGCGGATCACGCTGAAGTCGACCGACTTTCTGCGGATGGTGTGCGACGAGTGTCTGGTGAAGGTGGACCTGATTCGTGCCCTGCAGGAACAGTTTGCGCTGCAGCAGGACTATTACGGTGGGTACCTGGGGAAGGTCAAGCCCAAGCTGGAGATTGAGGAGGTCGAGTGGAAGGCGGAGGTGGTTCCGGAGCATTTTGAGGACGACtggaagccggagtcggaggaGGAAGAGGGTGACGATGATGAGGAAGAGTCTGAGGAGGAGAGTTCTTCGGAATCGTCGGATTCGGAGGATTTCGAGGAGGTTGTGGCGAAGAAGCAGAGAGGGAAGCGGAAAGCTCCGGTGAGGAGGacgaagaaagagaaaaaggTCGTGGTGAAGCGTAAGGAGGGGGAGCCTCAGATGTCGGCACTTGTGCCGAGGACGTGCAACATTTGCGTCAAGGTGTTTGATAACCACGGCGATCTGATGCTTCATTTGATTGAGCAGCACGGAAGTACGGAGGGATTTACGTGCGCCGCGTGTAACGATGGTCACAAGTTTCCGACCATCCAGCAGTACAACTATCATTTGGCCTATCATGACGCCTCGAAGCGACCGAACAAGTGTAGCTTCTGTCCGATTCGGTACCGATCGGTAGCGGCGTTGAAGCGCCATGAAAACTCCAAGCACGGCGCGAATCACAAGCTGAAGGGACGAATTGCCCGGGAATGCCAGTGTCACGAGTGTGGCAAGGTCTACACCGCCCAGTGGAAGCTCAACCAGCACATTCGGCACAATCATAGAGGGGTAATACCGCGATCGCATTGCAAAATTTGTCAGAAAAACTTCGCCACTGCGCTAGCCCTTCGAACCCACATTCTGGGCAGTCACGCCGGTCAGCGGCCATTCCAGTGCGAATCCTGTGACGCTAGCTACCGAACGTCAACCGATCTCAGGCACCACGTCAAGGCCGTCCACGAGGGCAAGAACCCGTTCCGATGTGGATCCTGCGATATCAGCTTCCGCACGAAGCGCGAATACGTCAACCATCGACACAACGAGCATCGCAACCGAAGAATGTACCATTCCTCCTGCAAGCTATGTCCAGAAATCCCGCAAAACAATACCGATCTCCTCGCGCACATCGCCGCCTGTCACGCCGACGTCGAGTATCCGCGCAATCAGTGCCCGCACTGTCCGGAAACGTTCCTCACCGCCCACGGCCAGGGCCAGCACAAACGCCTTGCCCATCCGGAGCATCTCCCGCTCGAGTGTCAAATCTGCCACAAAAAGTACTCCACGAAACTGTCCCTCAAAGAGCACGTGGACGTCATCCACCTGGGCAAACCTCCCACAATCAAGCGCAAAGGACGCCACGAGCCCCAGTCCTCGACCTGTCCAACGTGCGGCAAGCAGTTCTCCAGCAAGCAGAACCTCCAGCGGCACGAGAAGGCCGTCCACCTGGGCGAGCGTAACTTCCAGTGCGATCTGTGCCCGAAGGCGTTCAGCACGGCCACCGTGCTGCAGAACCATCGTCGCTGCGTGCACACCGGTGAGGCGCTGCACGAGTGCCCCGGCTGTGGCCAGCGCTTCAAGGAGAACGGCACGTTCTACCGCCACCGGGCCAAGTGCGCCCCGGAAGCGTCCACCAAGAAGGCGGCGGCGGCCAATCGTTCGTTTGTAGTTCTACTAAAGaacttgttttatttcatttgtttCCTGTCCGTGAACGTCTGGTTCTTGCCCCACCACCGTCTTCACCTCGCGATGCCTTGCCCTCCTGTGCCACGTGAGCGCCGTCCCGTTCACCAGCCGCACTTCCGGACACTGCGGACAGCTCACCCACGGGTACTGCTCGTCGCGGTGACTGACCGCAATGTGCGCCTCCAGGTCTTTCTTCCTGACGGGAACCTCCGGGCAGAGCGCGCACCGAAAGCGCAACCGCATCTTCCGATCGTTGCTCCGATTGTCGTGGACGCGGCGCTGATGCGTCCGGTACTGACCTTGCGATCGGAACGTCAGCTGGCACGGCTTGCACCGGAACGGGTCGGGACCGCCGTGGGCGGCGGCCATGTGGATGTTGAGGTTGGTTTTGGCGCGATACCGTACGCCGCACTGCTCACAACCGAAGGGACGCTCGTTGAGGTGCCACAGCTTGTGCTTCAGCAGAGCCTGGTCGGACTTGACGATCCGGTTGCACGTTGGACACTGGAGCTTGCGGGCCTCGTGCCGTGCCGCAATGTGCTTCCGGAGGGCGCCGATCGAGAGCAATATCTTGCCGCAGGTTTCGCACTGATGGTTCTTGTGGAGACGTTCCGGATTTCTGTATCTAATGGGCTTTCCGGCGTGGAGGTGGGCCACGTGCTCCCGGACCGATCTTCGCGTGCAGTATCGAAGCGGACAGAGCTTACACTGGAACGGTCGTTCCTTAGCGTCGTGAAACTTGAGGTGATTGTTGAACAGGGTCACCGTTTCGAACCGTTTTCCACCGCAGTCGGTACAGCTGAACTCGGACGGATCCCGATGATTCTCAACCTGGTGGGACACCAGCTCCTCGCGGGAATTGTACTCCACCTGAACGCCCTCGTCATCAACGACCCCCGGCACTTCCGGCTCCGGCGCGACCACCTCCAGCGGAGTCTTCAAGCTGTCCACCATATCCGTGGTCGCCTTCAACTCCCCAAATTCGGCCTGAATCTTGCGAACCACGTCGACCTTCACCAGACACCGCCGGCACACGAAACTCGTGTAGTCCCGCGGGTGGATCCGGATGCGGATCGTCGGGAAGAGCAAGCCCGCCAGTATGGTCCCATTCAGCGTTCCACTCAACCGACACATCCCACTCGTCGGCATGTACCGATGGCACAGCTTGCAGCACGTCAGGCTGACCCGTTTTTCCGGGTTCCTAGGGGTAAGAAGCAGAGTTTCTCAATTGAGTTGGCAGATGTCGCGCTCCCAAACTTACCGCTTGCTGGGAAAAATGGACGGTTCCTGGTAGAAGCGCTCGTCCGGATGGGTAAAGTGCGCCAGGCAGATCTTCAGCGGTTCGAGCTCGTCGTCGGAGCCGAGCGCGACGCCGGTGGCCAGCGCGATCACCCGGAACCATCGCCTGCGGAGCAGCAGGTGGTCCGGGAATCGCACCAGCAGCGTCTTGGCCGTGCAGGCCGGGATGCAGCAGGACATGCTTACTAttcGCTTCGGTTCCACCAAATTAACGAATCCGAAATGCCCTGCTGCGTGTTCCGCTGTCCGGGAGGGCCCAAGTTGGTGCGCTTCCCGGCCGTCCCGGCCCTTCGCGAGCGCTGGCTCGAAGCGATCCGTGCCGGTACGGGGGCCCGGATTTCGAGCGATCAGCTCCAAGGCAAGACGCTCGAGCTGTGCGTGTCCCACTTTGCCAAGGATCCGACCGAGTGCGGGGACGAGTACCAGGAACCGTCGCGGTTCATCAATCGTTCCGGCAAGCCGGTGAAGATCGGCAGCTGCCGGCTGTGCCATAGATTTGGTCCGGAGCGCGAAATGATCTCGCTGCAGGGCAAAGTGGCCGCAGACTTCCGCATCGACGTCATCCTGCAACAGCAATCGATCCTCAAAGTCGAACTTAATGCTTCGGACTTCCTGCAGCAAATCTGCCAGGAGTGTCTGGTTCGGGTCGAACTGATCAAGTCAATTCAGCGGGAGTTCTACTACAAGAACGCCACCTTCAAAACCCTTCAGAAAAACCTAAGCTCGCTGGAGGTTGTCCGGAGCAAGGAGACTCGCCGAAAACCATCACAACCCGTAATCGATTGCGACCTGCTGGACGAGGACTCGATCGCGGGGTTCACGATCGACAAAACGAATCCGCTGCAGCAAAAGTGGAACGTTCCAGAACTTCAGCCATCTCCGTCGAAGCTCATCGTAAAGCCGAAGAAACAACCCCGCGAACCTCCGCCAAATCAACGAACCTCCAAGTGCTACATCTGCCGGCTGCAGTTCCACGGCCGGGAAGATCTGATCAACCACCTGGAGCAGAGCCACGTGGTCAAGCCCCGGTACGGCTGCTCGGAGTGCAGTTCGAAAACGGCGCGCTTCAAGGAGATTACGGCGTACAACGTGCACCTGAGCTGGCACGACGAAGGGGAGCGGCCGCTCAAGTGTCGCACGTGCCCGCTCAGTGTATCATTTGAGTTTTGCTTgttgaaaaataacaataacaaacttTCTGCCGAATCTGTTGACACCTGCAGCGTCTCCAGAATGCCCTGCTGCGTCACCGGTTGCCCCGGAAGCGTCCGACTGGTTCAGTTTCCGTCCGACAGCGTACTCCGTCGACGCTGGCGCGATGCCATCGAATTTGCCATCGGAACCGGTCCGACCGTGGCCGAGGAGGAGCAATCGCTGGAGCTGTGCGAAGACCACTTTGAGAGTGATGCGAGTTCGGCGGAGCGCTATCGGGAACCGACGCGGTTCAGCGATCGATCAGGACATCCGGTGGAGCTCGGCAGCTGTCGGTTGTGCCACCGGTTCGAGGTCGCTTCTCGATTGTACTCGCTGGATGGACCGATGGCCGATGTGGACATCGGAACAGTTCTGCGCGAATCGATTAAGGTTCAGCTTGGTGATGACGATTTCCTACGGTTTATCTGTGGGGTCTGTTTGACCCAGGTCGGGATGGTTCTGACCATTCAGAAGTCGTTCCTCATCAAGGGAGATCCTGGCGTTGAAAATCTGGACAGaaccgACCCGCTAGCGGAAGTGACCTGCTGCAGGCTGTGTCATCGCTACGAATCAACCAATACGATGTGCTTCCTGGATGACGACCTGGCGGATGGTGTGACCATCGGTTCGACGCTGAACGCGATTCTCCAGTCGGAAGACGACTTGGCGCAGCTCATCTGTTTGAACTGCTTGGCAAAGATCGATTTGATGAGAAGCGTTCAGAGCTTCTTCGTCGGTAAGGATGAAGAGTTTCGGGGTTGGCAAAGGGAGGGTTTGGTAACGGTGGATCTGGACTGCCATCCAGAGCTGATGCTTGAGGTTAAGGTGGAACCGGTTGAGATTCAGGAAACGGCGAGGAAGGGCAGAAAGAGGAAGGCTAAAGAGAAAGAGTCAAAGTTGGTCAAAGAGAAGCCGCAGATTGAgtgcaaaatttgcaacaagaaGTTTGCGAAAAACCACAGTCTTAATTTCCACATGCTGATTCACACGGGCGAACTTCCGCACAAGTGCTCTCATTGCGATGCAAGCTTCCGGATGAGTACGGAGTTGAGCAAGCACGTGATGGGAGTTCATGAGGGTAAGACAGCGTACGATTGTAAGCAGTGCAATGTTCCGCTGGCAACGAAGACGGAGTACTACCGGCATCGCAAAACGGCTCATGCTACAGGTTACAAGAGAGTCGCCGTTTTGTACCGATGTCTGGTCTGCGAAAAGTCCTGTAAGAGTGTTGGCGAGATACGCAATCACATCGAGGCGCTTCACGCTGAGAACTATCCGTATCTGGAGTGTCCAGAATGTCCAAGGTTACAGCTGACGTGCGCTGCTCACGTCAAAGTTCACGGGTACTACAAGCATCCAGATAACGGAACCGTTGAACGATTCCCTTGCGATACGTGCGGCAAAGACTTTGACAAGAAGACACTGCTGCAGAAACACGTGCGAGCTGTGCATTCGGAACCCGGCACAAGCAAGGAATATGCCTGCTCACAATGCGACAAAACGTTTCGCTTGTACTCAACGTACCACCGGCACAAGGGCACTCACACTGGAATCAAGCGGTACGCTTGTACGATCTGCGAGCAGACCTTTAGTCAGCCAACCAGCCTCAAGTACCACATGCGAAACGTTCATACCCTGGAAAAGCCGTTCCGCTGCGAAGACTGTGGAGATTCCTTCCGTCTCAGCTCCGCCTTTAACAAGCATCGAGACAAGTACCACTCTCCGAACGCCGTCGTCGAAGACAAGGTTGCCTGTCCGACCTGCCTCGAGGAGTTTCTCACCAAGTCACTGCTCCAGCAACACGTGCGAAGCGTCCACGAGGAGCGAAAAGAGTTCGCGTGCCTTGAGTGTGGCAAGGTTTACAAAAACTTTGCCAACCTCAACCGGCACCGGGATTCGCACAACGAGACGCGCAAGCATCCGTGCTCGTTTTGTGACAAATCCTTTACGCAGCAGATTTCCCTCAATAATCACATCCGGAACCGGCACACCGGCGAAGAGCCGTTCATGTGCGCCGATTGCGGCGAAACCTTCAAGGATAGCTCCGTGTTCTACAAGCATCGTGCGAATCAGCATCCGAACCAGCAAGCCGGTCAAACGTTTCCGTGCGAAACGTGTGGCGAGCAGTTCGCGCAGAAACCGCTTCTGCTCAAGCATCGTCGGAGCGCCCATCTGAGCCAGCTCGTCTGTCCGGAGTGCGGCAAGCTGTTTAGCAGCTCGTCTACGCTGAATCGGCACCTGGAAACGCACAGCGGCACCCGGAAGTACGGCTGCTCGTTCTGCGAGCTGTCGTTCACGCAGCAAACTTCGCTCAAGAACCACGTCCGGAATCGGCACACCGGGGAAACTCCGTTCGGCTGCGACAAGTGCGGGGAAGCCTTCCGGGACAGTTCGAAGTTTTACAAGCACCGGGCCGAGTGCCGGGTGGAGGCGGTGGAGGTTAAGACGGAACCGGAAGATCCGCTGGGAGATGATCCGTGTCCGTGA
- Protein Sequence
- MVCCVPGCLPADTSGGLVRVVKFPTEDDLRRRWLQAVEIGSGTALDDDDADYQLCTGHFEWAGDEQEYREPTVFGGGNVASCRLCHQFLPVSRMVPSVGGGTFADMALDTMVALVLRITLKSTDFLRMVCDECLVKVDLIRALQEQFALQQDYYGGYLGKVKPKLEIEEVEWKAEVVPEHFEDDWKPESEEEEGDDDEEESEEESSSESSDSEDFEEVVAKKQRGKRKAPVRRTKKEKKVVVKRKEGEPQMSALVPRTCNICVKVFDNHGDLMLHLIEQHGSTEGFTCAACNDGHKFPTIQQYNYHLAYHDASKRPNKCSFCPIRYRSVAALKRHENSKHGANHKLKGRIARECQCHECGKVYTAQWKLNQHIRHNHRGVIPRSHCKICQKNFATALALRTHILGSHAGQRPFQCESCDASYRTSTDLRHHVKAVHEGKNPFRCGSCDISFRTKREYVNHRHNEHRNRRMYHSSCKLCPEIPQNNTDLLAHIAACHADVEYPRNQCPHCPETFLTAHGQGQHKRLAHPEHLPLECQICHKKYSTKLSLKEHVDVIHLGKPPTIKRKGRHEPQSSTCPTCGKQFSSKQNLQRHEKAVHLGERNFQCDLCPKAFSTATVLQNHRRCVHTGEALHECPGCGQRFKENGTFYRHRAKCAPEASTKKAAAANRSFVVLLKNLFYFICFLSVNVWFLPHHRLHLAMPCPPVPRERRPVHQPHFRTLRTAHPRVLLVAVTDRNVRLQVFLPDGNLRAERAPKAQPHLPIVAPIVVDAALMRPVLTLRSERQLARLAPERVGTAVGGGHVDVEVGFGAIPYAALLTTEGTLVEVPQLVLQQSLVGLDDPVARWTLELAGLVPCRNVLPEGADREQYLAAGFALMVLVETFRISVSNGLSGVEVGHVLPDRSSRAVSKRTELTLERSFLSVVKLEVIVEQGHRFEPFSTAVGTAELGRIPMILNLVGHQLLAGIVLHLNALVINDPRHFRLRRDHLQRSLQAVHHIRGRLQLPKFGLNLANHVDLHQTPPAHETRVVPRVDPDADRREEQARQYGPIQRSTQPTHPTRRHVPMAQLAARQADPFFRVPRGKKQSFSIELADVALPNLPLAGKNGRFLVEALVRMGKVRQADLQRFELVVGAERDAGGQRDHPEPSPAEQQVVRESHQQRLGRAGRDAAGHAYYSLRFHQINESEMPCCVFRCPGGPKLVRFPAVPALRERWLEAIRAGTGARISSDQLQGKTLELCVSHFAKDPTECGDEYQEPSRFINRSGKPVKIGSCRLCHRFGPEREMISLQGKVAADFRIDVILQQQSILKVELNASDFLQQICQECLVRVELIKSIQREFYYKNATFKTLQKNLSSLEVVRSKETRRKPSQPVIDCDLLDEDSIAGFTIDKTNPLQQKWNVPELQPSPSKLIVKPKKQPREPPPNQRTSKCYICRLQFHGREDLINHLEQSHVVKPRYGCSECSSKTARFKEITAYNVHLSWHDEGERPLKCRTCPLSVSFEFCLLKNNNNKLSAESVDTCSVSRMPCCVTGCPGSVRLVQFPSDSVLRRRWRDAIEFAIGTGPTVAEEEQSLELCEDHFESDASSAERYREPTRFSDRSGHPVELGSCRLCHRFEVASRLYSLDGPMADVDIGTVLRESIKVQLGDDDFLRFICGVCLTQVGMVLTIQKSFLIKGDPGVENLDRTDPLAEVTCCRLCHRYESTNTMCFLDDDLADGVTIGSTLNAILQSEDDLAQLICLNCLAKIDLMRSVQSFFVGKDEEFRGWQREGLVTVDLDCHPELMLEVKVEPVEIQETARKGRKRKAKEKESKLVKEKPQIECKICNKKFAKNHSLNFHMLIHTGELPHKCSHCDASFRMSTELSKHVMGVHEGKTAYDCKQCNVPLATKTEYYRHRKTAHATGYKRVAVLYRCLVCEKSCKSVGEIRNHIEALHAENYPYLECPECPRLQLTCAAHVKVHGYYKHPDNGTVERFPCDTCGKDFDKKTLLQKHVRAVHSEPGTSKEYACSQCDKTFRLYSTYHRHKGTHTGIKRYACTICEQTFSQPTSLKYHMRNVHTLEKPFRCEDCGDSFRLSSAFNKHRDKYHSPNAVVEDKVACPTCLEEFLTKSLLQQHVRSVHEERKEFACLECGKVYKNFANLNRHRDSHNETRKHPCSFCDKSFTQQISLNNHIRNRHTGEEPFMCADCGETFKDSSVFYKHRANQHPNQQAGQTFPCETCGEQFAQKPLLLKHRRSAHLSQLVCPECGKLFSSSSTLNRHLETHSGTRKYGCSFCELSFTQQTSLKNHVRNRHTGETPFGCDKCGEAFRDSSKFYKHRAECRVEAVEVKTEPEDPLGDDPCP
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -