Cpip016649.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Culex pipiens
Gene Symbol
-
Assembly
GCA_016801865.2
Location
NC:140198414-140230670[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 19 9.8e-05 0.003 18.4 0.1 1 23 184 206 184 207 0.95
2 19 0.00074 0.023 15.7 0.1 1 23 209 232 209 232 0.94
3 19 1.1e-05 0.00033 21.5 0.5 1 23 246 268 246 268 0.97
4 19 0.0008 0.025 15.6 0.7 1 23 274 296 274 296 0.98
5 19 1.8e-06 5.6e-05 23.9 1.0 1 23 302 324 302 324 0.99
6 19 9e-05 0.0028 18.5 1.3 1 23 330 352 330 352 0.98
7 19 1.1e-06 3.4e-05 24.6 0.4 1 23 358 380 358 380 0.97
8 19 5.3e-05 0.0016 19.3 2.0 1 23 386 408 386 408 0.98
9 19 0.0067 0.21 12.7 3.6 1 23 1063 1086 1063 1086 0.97
10 19 0.00017 0.0052 17.7 1.5 1 23 1091 1113 1091 1113 0.98
11 19 0.00085 0.026 15.5 1.1 1 23 1119 1141 1119 1141 0.96
12 19 0.0063 0.19 12.7 2.7 1 21 1147 1167 1147 1169 0.94
13 19 0.0015 0.046 14.7 1.9 1 23 1175 1197 1174 1197 0.96
14 19 1.4e-05 0.00042 21.1 0.5 1 23 1203 1225 1203 1225 0.98
15 19 5.8e-05 0.0018 19.1 0.1 1 23 1231 1253 1231 1253 0.98
16 19 9.5e-05 0.0029 18.5 0.2 2 23 1263 1284 1262 1284 0.97
17 19 8.8e-05 0.0027 18.6 0.7 3 23 1292 1312 1290 1312 0.97
18 19 3e-06 9.3e-05 23.2 2.2 1 23 1318 1340 1318 1340 0.98
19 19 0.0013 0.041 14.9 1.0 3 23 1348 1368 1346 1368 0.98

Sequence Information

Coding Sequence
ATGGCCACCGTCGTTCCCGagtgctgccgctgctgcctgACCGAGGACGAGCGCGACCTGATCTTCGTGTTCGACGTGCTGGACGAGTTCGAGAGCCGCATTTGCGACCTGATTGCAACGTGTGGCGGCATCGAGATTGCGGAGGAAGACGCATACTCCAAGAGCATCTGCGGCAACTGCCTCAACGATCTGGCCAACGCGGCCCGCTTCCGGGACCGGTGCGCCAAGACGGAACAGGTGCTGCAGAACGCGTCGATTACGGTGGTCGAGGAGGACGACGATGTGGTGTTTGAGCAGGAGCAGGACCAGCTGGACACGGCCGGGCTGGTTAAGCTTGAGGAGGAAGACGGCGACACGCGGGACAGTGGCGAGCCGAGGATTCAGTTCATCATCGCCGACGATCCGAACGATCCCGAGCTGGCCAAGTTCGACTACGACGAGCTGATCAGCAGCCAGGACAGCGAACTGCAGCCGGATGACTTTGAGGAGCTCAAAACCAAAGAGAAAAACGTTGAAAAGGTGGTTCGGCCCAGGCCACTGCAACTGAACTTTGTCTGTCCGGAGTGTGGAGCGGGCTTTGCGATGCAGAAGAATCTGGTCAAACATTTGGCCAGCCACCACAGCTTCGTGTGCGGCGTTTGCCTTAAGACGTTCGAGAACGAGTCCGATCTGCAGACTCACCTGGCTCAAGGTCACGACGACAGCAGCCCACCAACAGACAACCCTAAGAAGAAACACGTCTGCGAGTTTTGCCGCAAGGCGTTCGTGTCCAACTCGGCCCTCACGGCTCACATCCGCGTTCACACAAAGGAACGCCCCTTTCCGTGTAGCTTTTGCACGAAACGGTTCCGCACCGTCGGAGCGCTCGAGCTGCACGAACGACGCCACAACGGAATCAAGCCGTACAAGTGCGACATCTGCGGGCGTGGCTTCGCCGAGTCGAGCAACCTGAAGGTGCACCACCAAACGCACACCAAAGAGAAGCCCCACGTTTGTACCGTGTGCAATCGGGCCTTTGCGCGGGTCTTCCTGTTGAAGATTCACCAGCGGACCCACACCGGAGAGCGGCCCTTCGCCTGCGTGGATTGCGGCAAGTGTTTTTCGCAGCAGGGTGATTTGGCCGCCCATCGGAGGATTCACAGCGGGGATCGGCCCCACACGTGCGACGTTTGTGGTCGCAGTTTTATTAAAAGCAGTGGCCTGCTTCAGCACCGCAAGAGACATAAGCTGGCGCTGGGTGGAGAGGTGCTGGACGGCGTGGAGGAACTCATTGTCGGGGAGTTTGAAGTTGAAGAGGATCACGGCGAGGAGGAAGAGAGTGGGGACGGCGAGGAGGTGTTGGGTTTAGtATACTGGCAGTTGACCTGGGCCACATCGTACACGATATACTCGTTGTATAGCAGTGCCGACTGCAGCTTGGAATCGGTCACGCCCGGTCCCATCGGGATCTCGACGCCGTCCGCTGTGCATGTTGTCGGGGAGTTTCTGCACGTACCGGGCCTGGTTCAGCTCCATCATGTTACCGAGGGCCACCTCGCACAGCAGCATCAGACCGGTCGAGTTTGCGGGCGAGGTTGCGCAGTAGTTGGCGGATTTGGACACCATGTCGGCGAAGTAGATACCCTTGCCGAACATGTACCCGGTGACGGGGGCTTCCGGCGGGGCGATCTTGAGACCGTGCGTGAGAATACCGACAAAGTTGGTAAGACGCGATCCGTGCCAGAGGAGTTTGCGGTTGTGCAGCTTGCGGAACGGTTTGTAGCGACGCTCTTCGCCCTTGCGGcggattttgaagatttccgaGACTTCCAGGTCGAACTGGTTGTGGGTGGCGGCGTGCGTGTTCTTGACGTACTGGGCGAGGCGCTTGAACTCGTCGGACTTTTGGTCCAGCGTTTGCATCTCCGTCTTGAGCTGGTCGTAGTGGCCGTCGAGCGGGTTCTTGGTTTCGTCCGTGTCGGCGTTCAGCAGACTGTACGCGATCTCGATCTCCATGAGGCTTTCGAGCATGGTTTGCTTTTCCTTGATCTGCTCGACGGTGTCGAGGACGGGGAATCTTCCGCCCAAACAGGATTTTTTCTCCGCGGTCGCGTTTCACTTTCTCAAAATGATTCGATTCGTTGTGTTTTAATCCCGCGCACGATGGACGGCCCTTTCGTGACATTCTGCGCGGAGCAGGCGCACCCCACCAGTGAAGCAATTCCGGAATCCTCCTCCGTCGTGGTCGTCACGGAAGAGGACGATTCTGGCGAGCCGCAAGTCGCGGCGACGGCTGGTGGTCCACCGAAAATCGTTTATCTGGACCGGGTTTGTCGGACGTGTTTGGTCGAGAAGGAGAGGGATGACCTGAAGGATCTGTTTGAGTTTGGGCTGGCGGAAACGGTCATGTCCTGTGTGGGTCGGGTCATTTCGGTGGAGGAATCGGACGGGTTGCCGGGTCACATATGTATGGAGTGTCTGCAGGAGGTGGAACGGATCATCAGCTTCCGACAGCAGTGCGAGCGATCGGACGGCACGATCCGGAACTTGATCGAGAAATCCGTCGTGATCAACCAAGACAGCGAGACCAAGTACGAAGTGCTGAACGTGGTGCTGACCGATGCCAACGGGAACACGGAAACGTCGGCCGTTGTCGTTCCGATTGAGGAGCTGCGTTTTCAGCTGATGAATGGCGGAGGGGGAGGAAGGTGTTCCGAGGAGATTGTAGAGACGGAATCGACGACCAGCGAAAACGTCGAGCTGAGCTTCGTGGCTCCTTCGGACATACTTGTAACGGAGGAGATCATTGTCCAATCGCAACCGGAGGAGGAGGCTCCGATCGGTGAACTGATTGTCGAAGAAACGCCTTCAGagcaggagcagcagcagcatgaaTCGACGGTTCTGGAAAACCTGCGCCAAGAACTGTCCGAATTCATCGGTGGAACGAGCGCGGAGATCCCGAAAGATCAAGAAGACCtggacgaaaacgacgacgacgaattaCCTTACGATTACCTCAAAGATGCCCTCACCGACGAGTACATTCAGTCGATGGAACAGCAGCTGGCCCCGTCGGCCCCTCCGCGGTCGGAAAACCCCGCCCAGGAACGCTTGGAGCAGGCCAACCTGGACAGTCTGATCAACGATGAGCCACAGCAGCTGCGAGGTGACGGTGGCGACAAGGACCATGGCGCCAGTAAGCAGCACTACTGCGACGATTGTAACGTGGGCTTCGAAAATCGGCGCAAGTTCCGGGTGCACATGAAGAAGAAACATTCCGAGAAAAAGTACGAGTGCAGCTACTGCTCGCGCCGGTTCGCCGAGCAGAAGCAGCTGCGGAACCACGTGCTGCGGCACACCGGCGAAAAGGCCCACGCCTGCGAGATATGCAACGCGCGCTTCTACGAGCGCAACTTGCTGAACGTGCACATGCGGCGACACGACGGCGAGAAGCCGTACTATTGCGAGCTGTGCCCGAAGCAGTTCGGGAGCAAAAGTCTGCTCAACACCCACGTCAAGTGTCACCGCGGCGAGAAGTGCCACATCTGCGACGTGTGCGAAAAGGGCTTTACGCTCAGCTGGCAGCTAACGGCTCACAAGCGCATTCACACGAACGAAAAGCCGTACGAGTGTCCGTACTGTCTGAAGCGGTTCAACCAAAATGGGAATCTGGTGATTCACAAGCGAATCCACACGGGCGAGCGGCCTTTCCAGTGTGAACTGTGCGAAAAGGCCTATCCGGGCCAGGGAGAGTTGAggAACCACATGCGGCAACACACGGGCGAGAAAAAGGTCAAAAACGTGACGTGCACCGTATGTCAGAAGAACTATGCCGGAAATGGGGACCTCAAGATCCACATGCGAACCCACACCAAGGAAAGGCCTTACGGCTGCCAGGAGTGCGGCAAGACGTTCATGCTGCAGGTTCACCTGACGGTGCACATGAGAGCCCACACGGGCGAAAAGCCCTATGCGTGCGAGCTGTGTCAAAAAGCCTTTACCACAAACTACCAGCTGAAGCACCACATGCAGGTGCACACGGGCGAGAAGAACTACGGCTGCGATTTATGCGACCGGCGGTTCAGCAGCGCTGCCAACCGGAACACCCACCGCAAGACGCACGAACGGACAATCTCCTGA
Protein Sequence
MATVVPECCRCCLTEDERDLIFVFDVLDEFESRICDLIATCGGIEIAEEDAYSKSICGNCLNDLANAARFRDRCAKTEQVLQNASITVVEEDDDVVFEQEQDQLDTAGLVKLEEEDGDTRDSGEPRIQFIIADDPNDPELAKFDYDELISSQDSELQPDDFEELKTKEKNVEKVVRPRPLQLNFVCPECGAGFAMQKNLVKHLASHHSFVCGVCLKTFENESDLQTHLAQGHDDSSPPTDNPKKKHVCEFCRKAFVSNSALTAHIRVHTKERPFPCSFCTKRFRTVGALELHERRHNGIKPYKCDICGRGFAESSNLKVHHQTHTKEKPHVCTVCNRAFARVFLLKIHQRTHTGERPFACVDCGKCFSQQGDLAAHRRIHSGDRPHTCDVCGRSFIKSSGLLQHRKRHKLALGGEVLDGVEELIVGEFEVEEDHGEEEESGDGEEVLGLVYWQLTWATSYTIYSLYSSADCSLESVTPGPIGISTPSAVHVVGEFLHVPGLVQLHHVTEGHLAQQHQTGRVCGRGCAVVGGFGHHVGEVDTLAEHVPGDGGFRRGDLETVRENTDKVGKTRSVPEEFAVVQLAERFVATLFALAADFEDFRDFQVELVVGGGVRVLDVLGEALELVGLLVQRLHLRLELVVVAVERVLGFVRVGVQQTVRDLDLHEAFEHGLLFLDLLDGVEDGESSAQTGFFLRGRVSLSQNDSIRCVLIPRTMDGPFVTFCAEQAHPTSEAIPESSSVVVVTEEDDSGEPQVAATAGGPPKIVYLDRVCRTCLVEKERDDLKDLFEFGLAETVMSCVGRVISVEESDGLPGHICMECLQEVERIISFRQQCERSDGTIRNLIEKSVVINQDSETKYEVLNVVLTDANGNTETSAVVVPIEELRFQLMNGGGGGRCSEEIVETESTTSENVELSFVAPSDILVTEEIIVQSQPEEEAPIGELIVEETPSEQEQQQHESTVLENLRQELSEFIGGTSAEIPKDQEDLDENDDDELPYDYLKDALTDEYIQSMEQQLAPSAPPRSENPAQERLEQANLDSLINDEPQQLRGDGGDKDHGASKQHYCDDCNVGFENRRKFRVHMKKKHSEKKYECSYCSRRFAEQKQLRNHVLRHTGEKAHACEICNARFYERNLLNVHMRRHDGEKPYYCELCPKQFGSKSLLNTHVKCHRGEKCHICDVCEKGFTLSWQLTAHKRIHTNEKPYECPYCLKRFNQNGNLVIHKRIHTGERPFQCELCEKAYPGQGELRNHMRQHTGEKKVKNVTCTVCQKNYAGNGDLKIHMRTHTKERPYGCQECGKTFMLQVHLTVHMRAHTGEKPYACELCQKAFTTNYQLKHHMQVHTGEKNYGCDLCDRRFSSAANRNTHRKTHERTIS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-