Cpip018709.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Culex pipiens
Gene Symbol
-
Assembly
GCA_016801865.2
Location
NW:6-9429[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 36 0.00044 0.014 16.4 1.4 1 23 120 142 120 142 0.98
2 36 0.00028 0.0086 17.0 1.2 1 23 151 174 151 174 0.97
3 36 0.032 0.99 10.5 0.1 2 23 184 206 183 206 0.94
4 36 4.3e-05 0.0013 19.6 0.6 1 23 213 235 213 235 0.99
5 36 0.00044 0.014 16.4 0.2 1 20 240 259 240 261 0.92
6 36 0.31 9.4 7.4 0.9 2 21 268 287 267 288 0.91
7 36 0.0051 0.16 13.0 1.3 1 23 362 385 362 385 0.94
8 36 0.016 0.49 11.5 3.2 1 23 400 423 400 423 0.97
9 36 2.9e-05 0.00088 20.1 0.8 2 23 624 646 623 646 0.94
10 36 0.011 0.34 12.0 2.3 1 23 667 690 667 690 0.94
11 36 0.016 0.49 11.5 2.6 2 23 704 726 704 726 0.94
12 36 5.4 1.7e+02 3.5 0.2 2 22 737 757 736 757 0.92
13 36 0.014 0.42 11.7 2.5 1 23 771 793 771 793 0.98
14 36 0.1 3.1 8.9 1.0 2 23 800 822 799 822 0.95
15 36 0.029 0.88 10.7 0.3 2 23 848 870 847 870 0.93
16 36 0.011 0.32 12.0 1.2 1 23 891 914 891 914 0.95
17 36 0.014 0.43 11.7 3.9 1 23 929 952 929 952 0.96
18 36 0.018 0.54 11.3 1.6 1 23 994 1016 994 1016 0.97
19 36 0.013 0.39 11.8 1.0 1 23 1022 1045 1022 1045 0.97
20 36 0.26 8 7.6 0.8 1 23 1052 1074 1052 1074 0.96
21 36 0.0094 0.29 12.2 7.8 1 23 1079 1102 1079 1102 0.91
22 36 7e-06 0.00021 22.0 0.4 2 23 1117 1138 1116 1138 0.97
23 36 0.0006 0.018 15.9 0.4 1 23 1144 1168 1144 1168 0.97
24 36 0.00049 0.015 16.2 2.5 1 23 1271 1293 1271 1293 0.99
25 36 0.0038 0.12 13.4 0.3 3 23 1304 1325 1302 1325 0.97
26 36 0.025 0.78 10.8 0.1 2 23 1335 1357 1334 1357 0.94
27 36 6e-05 0.0018 19.1 0.6 1 23 1364 1386 1364 1386 0.98
28 36 8.4e-05 0.0026 18.6 0.2 1 20 1391 1410 1391 1412 0.92
29 36 0.064 2 9.6 0.9 2 21 1420 1439 1419 1440 0.93
30 36 0.11 3.4 8.8 0.5 1 23 1510 1533 1510 1533 0.93
31 36 0.059 1.8 9.7 5.6 2 23 1548 1570 1547 1570 0.96
32 36 0.00078 0.024 15.6 3.1 1 23 1742 1765 1742 1765 0.94
33 36 0.0078 0.24 12.5 5.1 2 23 1779 1801 1779 1801 0.95
34 36 0.17 5.1 8.3 0.3 1 20 1843 1862 1843 1865 0.92
35 36 0.0043 0.13 13.3 2.6 1 23 1871 1894 1871 1894 0.94
36 36 0.0012 0.037 15.0 4.3 2 23 1918 1940 1917 1940 0.94

Sequence Information

Coding Sequence
ATGAAGTGCCTGGTTCCGTCTTGTGACACGCCTACGGACTTCAACAAATTGCCTAAAGGATTAACTAGGCACCATTTCCCTGCCGACAATATACGGCAGGTCAAATGGCTGCAAGCTATAGCAAAGGCCGAAAATTGCCATCCGAAAGACCTAAAAATTATCAATAATGACCGCATTTGTTCGAGGCATTTTCGACCAGATTCTTTTTACAAGCTGAACAATCGAGTTATGTTGCACAAATACGCAACGCCATTTGCTGACGACAAAAATGCTGAATTAAGGTCGGAAGACAATCAAAACCTAATGGAAGCAGCAGATTTGCTCCCACGAGAACCAAAACCCCCCAAAAAGCACCTCTTTCAATGTGAAATCTGTGACAAAATTCTCTCAACCAAGCAGTCCCTCAACaaccacaaaacaaaacatctCGACCCAGAACAACGGGAAACCTTCCGGTGCGAGATATGCGAGGCCACTTTCAAGTCCAAGTACGGTTTGAAATACCATCTGGAAACGAAGCACATCGCGGAGAATGAGCGCAAGAAGCTGCCCTGTCCGACGTGCGGGCGGATTTTCAAAAGTGACGAGGGCCGGAAGATCCACATGACCATTCAGCATGGGGCCGGAGGACCGATCTTCAAATGCAAAGAATGTCCGATGGTATTCGCGCGGAAGCCCCACCTAGATCTGCACATGGCAACTCATGGCGCGGGGCTGCACGTTTGCTCGATCTGCGGGAAGTCGTACGCCAGGCTGAAGGACCTGTCCCGGCACGAGGCCACCTGTGGCGTCAAGGAACTGTGCTGTCTGGAGTGTGGGAAGCAGCTTCGGAGCGAGCAAGCGCTTGAAAATCACCGGAAAAAATGCCGTTCGAGAGGTTTGAGATGTGAAGTCGGTGACCGTGAGAAGCGGGAACGTTCGAAGAAGAGCGATTTGGGCGGCGAGGAGGGCAAAGTTCGCATGAGGCGCAGCAAACATGACCGGTTTCTTGGACTGGACCATTTGGTGGATCCATCTTCGCTGATTGAAGAAGCTGAACCGGTGGAGCTTGAACCCAATGCGGTACATTTCACTCCGAAGAGTTTTCTCTGCGAACATTGTCCGCTGAAGTTTGCTTCAAAGCAAGCACTGCAGAATCACGCACAGAGACGGCACTGGGAAGTTATGGGTATTGCGGAACCAACTTTTGTGAGAAGGTTCCAATGCGTGCAATGTCAGTTTAAGTTTTATACAAAGCAAGCACTGCAGAAACACGAGCAGCGACGGCactgggatgttctgggtcttacAAAACCACTTATGAAACGAGGATGCAAGAAAAAGCGGGTTCCGAAGAAGCTAGGCAGACCGCAGAAGATGGGCAACCATGTCGAACTTGACGAATTGCCAGCAGAAATTGAGTGCGACACCAAAAAAGAGGAAGTTAATCCGATCGAATCAGAAGACGTCGCACACGGAGATCCGATGTTCGACGAACCTATTGAGAACGTGGAAATTTCTGAAGACGTTGAGCGAAACGAAGAAAATGGCGAGCAGACGAAAACTTGTGAAAAAGCAACACCAGATACAATTTTAACAGACGAAGTTGACATCAAGGATGAGATTGAGTTTGGGGAGTACGAATTCAACTATTCAACAGAAAACGATAATAACGTTGATGAGGGAACGTTTGAGCTCATTACGACTGATCTTGTAATCCCACAAGGGCCAATCAAAGAAGAAGTTGATGCTCTTGGAGTTGAACCAGACCTGGAGAGCAACGTGTCGGAGGAACCACACATTTTCAACGAACTCGTCATCAGATTGGAGAAACTGGATTATTCTGCCCTCGCGGAGTCCAGTAGCGGCAAGAAACATTTTAATCGGAAGGAATGCGAACATTGTGGAAAAGCGTTTGCACGTCAGTACGATCTAGCGAAGCACCGGGTCAGGGAACACGGAAGTACGGAAACGCCAACGAGAATCAAACCACCACCAAAGATGGCACTCCCACCAAGCTACCGCTGCGAGGAGTGCGATAAATCGTACCAGTTTGAGCATTACCTTAAGGCGCACAACGAAAAAGTGCACGGCATCACGGAAGAACCTGGTGAAGGTGCTAATATTCGAACCTGTAAGCACTGCGGACAGAAGTTGAAATCCTGGCCAAGTCTGGTcaaacatttgaagtttttccaCGCAGAAAGTATCGACGAATCGCAGTTCGTTAAATGTCCGTCGTGTCCTGCAAAGTTTCTTAATCAGGAAGACTTGAACGGGCACGTCTGCACCAAGAGTGGCGTTTGCGAAAGGGAACCAAGGGAGCGTTCCTTCAAGTGTGATCTGTGCCGTAAAACGTACTCTTTCCTCCTTCATTTGGAAGCGCACTATTCCGTGCATCCAGAATATCAGAACTTAAGATGTGACCAATGTTCGAACGGATTCTACAACGAGAGGGAGCTGAACAAACACAAGAAGAACGCGCACGAACCGGTGGTGAAACCTGCGGTGACGAAGATTCGCCCCTTCAAATCCAAGTACAAAAATCCGTTTCCCAGGACGGAATGCGAACAATGTGGACAAACGTTTGCCTACCGATACCGATTAGCACTGCACCGGGTCAAGGAACACGGAAGTACGGAAATACCAGTGGCAAACAGACCAGCAGCAAGTACGACGCTTCCACGAAACTTCCCTTGTGACCAGTGCGATAAATCATACCATCTTCAGACTAATCTCATGATTCACAAGGCTAAGGTTCATGGCGTGGGAGAAGCCCCACCAAAAGAAGTTACAATATTAAAGCACACCTGCAAGCACTGTAAGAAACAATTCACAGCCTGGGGCGCTCTGATCTACCATCGAAAGTACATCCACGGAGAAAGCATCGAAAAGACGCAATTTGTGCAATGTCCGTCGTGTCGTTTGAAATTCGCAACCGACGAGGAAATGGCGGAGCATCTGTGCCTTAAGGGAGTCATTCGCCGAAGGGAACGTCCCTTCAAGTGCAACCTGTGCGATAAATCTTATTTCGCGAAACCTCATCTGGAGGGCCACTATTCCGTCCACCCGGAATACCACAACTTCAAGTGTGATCAATGCTCGAAGGGTTTCTTTGCCGAATCAGAGCTCATGAGCCACAAGAAGAAAGCACACATTGCAAAAGAGTTGTACTACGCGTGCGAGACCTGCAATCAGCTGTTCAAAAGCCAACAAATCTTGAACCGACACCGGGAGCTTCACATGGGCCGCGAGTACTGCTGCGAGCATTGtggcaaaaagttcaaaatgcgAACAAACCTCAAATCGCACGTGTACCACGTGCACGCCGAGTACGCGAGCGAGGCCGCCCGAGCCGCTCAAGCGATCCCTTGCACAGTCTGCGGTAAAACGTTCAGAGGAACGAGCGCTTACAGGCAGCACATGCGAACTCACAGCAACGATCGACGGTACAAATGTTCCTTTCCGTCCTGTGGCAAAACCTTCACCGCGAGCGGCAGTTTGAAAGTTCACGTGCAAAGTCACACGAAGGATTACAAGTACAAGTGCAAGTTCTGCGAGTACGGGACCGTTTTCCGGAAAAGAATTGTTTTGCACGAGCAGCGGAAGCACAACCATAACCGGTTCGCGGGAGTGAACGATTCTGATCGTATCGAACCAAGTGGATGTCGAAAGTCGAAAGGTACACGAACTGTTAGGCGAAAAACCGCAGAGCCCTTAAACATGGAAGTGAATGAATCCCTTGAAATGGTCGAATCAAAGCATGATTTCAACCAAGATCCGGAAGACGACGAAATTCTTCCACCGGAAGTAAGCCCCCCGAGGCATCCCTTTCAATGTGATATCTGCGACCGAATCCTCACGACCAAACAATCGCTTCATGTCCACAAGCGCACTCACGCAGATCCGGTCGTACGGCCAATGTTCGGTTGCGAAATCTGCGGGGCCACGTTCAAATCCCGTACCGGCCTGAGTTACCACCTGGAAACGAAGCACATCCCCGAGAATGAGCGCAAGAAGCTGCCCTGTCCGACGTGCGGCCGGATTTTCAAAAGCGACGAGGGCCGGAAGATCCACATGATCATCCAGCACGGCGTCGGCGGGCCGATCTTCCGGTGCAAGGAATGTCCGATGGTATTCGCGCGGAAGCCCCACCTAGATCTGCACATGGCAACCCACGGCGCGGGCCAGCACGTTTGCACGATCTGCGGGAAGTCGTTCGCCAGGCTGAAGGACCTGTCCCGGCACGAGGCCACCTGTGGCGGCGTCAAGGAACTGTGCTGTCCGCAGTGTGGCAAGCAGCTTCGGAGCGAGCAAGCGCTTGAAAATCACCGGAAAAAGTGCCGATCGAGCGGTTTGATGGGTGAAGGCGGTGAGAAGCGGGAACGTCCGAAAAAGAGCGGCGAGGAGGGCAAGGTTCGCATGAGACGCAGCAAACATGACCGATTTCTTGGACTGGACCATTTGGCGGATCCATCTTCGCTGGTCGAAGCAGCTGTTGATCCGACCAAGGTAGAGCCGAAACCAGTAGACCCCTACCCGAAGCGATTTCCGTGCGAGCATTGTCCGTTGGACTTTGCTTCGAAGCAAGCAATGCAGTATCATGCACAGCAACAGCACTGGCAAGTTATGGGGCTTGTGGATCCAGCGGAGAGAAGGATCCAATGCGTGCATTGTCCTTACAAGTGTTATAGAAAGCAAGAGTTGCAGAAACACGAGCGGCGAAAGCACTGGGATGTGCTGGGTCTTGCGAAACCAACTATTCTGAAGCGTGGACGGAAGAAGACGCGAAAGGAGGTCGACTATGTTGAACTTGAGGGATTGCCAGCAGAAGTGGAGTGTGACGTCAAGAACGAGGAGGTTGATCCGGTGAAGTTGGAAGATACTTTCGCTGAGGCAAAAAATGAGTCCTGCGAACCAACAGCTGATGGCTTTGCAGCGAACGAAGTTTTCATCAAGGATGAGATGGTCGATTTTGCAAATGACTTCGATCTGGATTACTTCGAGAATGACTCGACGGAAGGCGACGAGCTCGTTGAGAGCATTGCGGCGAATGTTGACAACCTGCAAGAGCCAACCAAGGAAGAGGTTGACACTCTTGACGTTGAACCGGCGCTGGAGGAGGAACCACGCGTTTTCAAAGAACTCGTCATCAAGTTGGAAAAGCTAGATTATTTCGCGCTGGTAAAATCAAGCAGCAACGAGAAACGGGTCAAGAGGAGCAAAACAACGCCCGCTTCAAGCTACCGCTGCGAGAAGTGTGATCGATCGTACAACCATAAGGGTAACTTCAAGGCGCACAACGAAAAAGTTCACGGCATTACGGAAGAAGCTGACGAAGGTGCTTTAACACGCTCCTGTAAGCACTGTGATAAACGGTTCAGAAACTGGACTCAGCAGCTCAGACACACGAAGCAACTCCACGGTGAAACCATCGACGAGTCGCAGTTTGTGCAGTGTCCGGCGTGTTTTGCAAAGTTTTTCAATCAGGAAGACATGAAGGAGCACGACTGCCCCAGGAGTTCCGAGCGCATGGCGTTACGTCCGTTCAAGTGTGACCGGTGCGATAAGACGTACGCTCTCCTAACGCAACTGGAAGGCCACTATCCCGTTCATCCGGAGTACCAGAACTTTAAGTGCGACATGTGTCCAAAGGCATTCTTCAAGGAAAGCACGCTGAAATCACACAAGAGCTACAAGCACGGACCGCGGACGCACATAATTCGAAAGTTTAGATCCAAAGCCAAGTTGAATAAACCGTTTCCCAGGAAGGAATGCGAACATTGTGGACAAACGTTTGCACACCAATACCATCTAGCGCAGCACCGAGTCAAGGAACACGGAAGTACGGAAATACCGGTGGCAAACAGACCAGTT
Protein Sequence
MKCLVPSCDTPTDFNKLPKGLTRHHFPADNIRQVKWLQAIAKAENCHPKDLKIINNDRICSRHFRPDSFYKLNNRVMLHKYATPFADDKNAELRSEDNQNLMEAADLLPREPKPPKKHLFQCEICDKILSTKQSLNNHKTKHLDPEQRETFRCEICEATFKSKYGLKYHLETKHIAENERKKLPCPTCGRIFKSDEGRKIHMTIQHGAGGPIFKCKECPMVFARKPHLDLHMATHGAGLHVCSICGKSYARLKDLSRHEATCGVKELCCLECGKQLRSEQALENHRKKCRSRGLRCEVGDREKRERSKKSDLGGEEGKVRMRRSKHDRFLGLDHLVDPSSLIEEAEPVELEPNAVHFTPKSFLCEHCPLKFASKQALQNHAQRRHWEVMGIAEPTFVRRFQCVQCQFKFYTKQALQKHEQRRHWDVLGLTKPLMKRGCKKKRVPKKLGRPQKMGNHVELDELPAEIECDTKKEEVNPIESEDVAHGDPMFDEPIENVEISEDVERNEENGEQTKTCEKATPDTILTDEVDIKDEIEFGEYEFNYSTENDNNVDEGTFELITTDLVIPQGPIKEEVDALGVEPDLESNVSEEPHIFNELVIRLEKLDYSALAESSSGKKHFNRKECEHCGKAFARQYDLAKHRVREHGSTETPTRIKPPPKMALPPSYRCEECDKSYQFEHYLKAHNEKVHGITEEPGEGANIRTCKHCGQKLKSWPSLVKHLKFFHAESIDESQFVKCPSCPAKFLNQEDLNGHVCTKSGVCEREPRERSFKCDLCRKTYSFLLHLEAHYSVHPEYQNLRCDQCSNGFYNERELNKHKKNAHEPVVKPAVTKIRPFKSKYKNPFPRTECEQCGQTFAYRYRLALHRVKEHGSTEIPVANRPAASTTLPRNFPCDQCDKSYHLQTNLMIHKAKVHGVGEAPPKEVTILKHTCKHCKKQFTAWGALIYHRKYIHGESIEKTQFVQCPSCRLKFATDEEMAEHLCLKGVIRRRERPFKCNLCDKSYFAKPHLEGHYSVHPEYHNFKCDQCSKGFFAESELMSHKKKAHIAKELYYACETCNQLFKSQQILNRHRELHMGREYCCEHCGKKFKMRTNLKSHVYHVHAEYASEAARAAQAIPCTVCGKTFRGTSAYRQHMRTHSNDRRYKCSFPSCGKTFTASGSLKVHVQSHTKDYKYKCKFCEYGTVFRKRIVLHEQRKHNHNRFAGVNDSDRIEPSGCRKSKGTRTVRRKTAEPLNMEVNESLEMVESKHDFNQDPEDDEILPPEVSPPRHPFQCDICDRILTTKQSLHVHKRTHADPVVRPMFGCEICGATFKSRTGLSYHLETKHIPENERKKLPCPTCGRIFKSDEGRKIHMIIQHGVGGPIFRCKECPMVFARKPHLDLHMATHGAGQHVCTICGKSFARLKDLSRHEATCGGVKELCCPQCGKQLRSEQALENHRKKCRSSGLMGEGGEKRERPKKSGEEGKVRMRRSKHDRFLGLDHLADPSSLVEAAVDPTKVEPKPVDPYPKRFPCEHCPLDFASKQAMQYHAQQQHWQVMGLVDPAERRIQCVHCPYKCYRKQELQKHERRKHWDVLGLAKPTILKRGRKKTRKEVDYVELEGLPAEVECDVKNEEVDPVKLEDTFAEAKNESCEPTADGFAANEVFIKDEMVDFANDFDLDYFENDSTEGDELVESIAANVDNLQEPTKEEVDTLDVEPALEEEPRVFKELVIKLEKLDYFALVKSSSNEKRVKRSKTTPASSYRCEKCDRSYNHKGNFKAHNEKVHGITEEADEGALTRSCKHCDKRFRNWTQQLRHTKQLHGETIDESQFVQCPACFAKFFNQEDMKEHDCPRSSERMALRPFKCDRCDKTYALLTQLEGHYPVHPEYQNFKCDMCPKAFFKESTLKSHKSYKHGPRTHIIRKFRSKAKLNKPFPRKECEHCGQTFAHQYHLAQHRVKEHGSTEIPVANRPV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-