Ccup020294.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Ctenicera cuprea
Gene Symbol
BCL11B
Assembly
GCA_958336395.1
Location
OY284488.1:56661046-56676447[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 7 7.6 8.5e+02 2.4 0.1 2 11 17 26 16 29 0.86
2 7 7.4 8.2e+02 2.4 1.5 1 23 182 205 182 205 0.93
3 7 9.3e-07 0.0001 24.2 2.8 1 23 473 495 473 495 0.96
4 7 2e-05 0.0022 20.0 4.4 1 23 501 523 501 523 0.99
5 7 2.5e-07 2.8e-05 25.9 2.9 2 23 716 737 715 737 0.97
6 7 1.8e-05 0.002 20.1 3.3 1 23 743 765 743 765 0.99
7 7 0.00012 0.013 17.5 0.4 1 22 773 794 773 794 0.97

Sequence Information

Coding Sequence
ATGAcagACTCAGACGGGGCGGATCCAGACGGTCACCAGGACATCCTCACATGTGGAGTCTGCCAAAAACCGTTCGCCCTCTCAGATATCGTCAGATTTATCCAGCACAAAGTAGCATCTTGCAACAAAGAAAATTTCGCAGGCGGTCACTGCTTTCAGGGGGCAGATAGGGAAAGAGACAATGATGATGGAGCGTTACCCCTTTCCACCATTAATACGAGGCGGCCTAGCATATCTGCCCCCATTTCCGGGAAAAAGGCGTCCGGGAGCAGCACAAGAGTGCACACACCGCCGCCTGCGTCCCCGAGGTTACCGGCTCCTGGGGATTTGTGCGTCGACGGGGCAGCTTCGTCTACTCCGAAGAGACGCGCTTCATCATCTCCCTTGACGTCCTCAAGTTTAGAGGATGGAGAAGACGTTAAACCTAACATAAAGCAGGAGAGAATGGAAATGAGCTCGTCATCGGAAGAACCCAGTCATAAGAAGTCGAGGACTGAGGTTGCTGATGCTGAATCAAATACAACAAATAGTGAGCCCAACAACTACGTGTGCTCGACGTGCAAGGCTCGAGTACATTCGGCGTGGCGTCTTGTACAACACGTACAGCACTCCCATGGGGTGAAGATATACGTCGAGACGTCTTCCAGTAGCAACAATAACAGCGCAAGCAGTTCCAGCAGTTCATCGTCAGGATGTTCATCTGGTGGACCACCACCACCTCCCAGTATCAGGCATCACATGCTACCTCCTCCTGATCTCCACAATCCCTTTAGCGTTGGAGGTTTGTTACGATTACCTCTCCCCCCTTTAAATCATGGACCAGTTCCACCAGCACCGCTCTTTTCTAGACCTGAACATCACTTTCGCATGGAACAATTGGTTACTGAACAATTTCGGCACCATGGGCTTAATTTAGCGGCGGCGGCAGCTGCCGTGGCTGCCGGAGGGGTCCCACCTCCGCATGCAAGCTTTCCATCGCCTGCAGAACGACCTCCAGTAGTTCCCGGCGTACCATCTAGAGAACGAAGCACTCCTAGCCAACCTCTTTCCTTAGAACCGCAACTTGATTATTATTCTCAAAGATTAAGGCAACTTGCTGGAACTACTAGTCCAGGTGCGGCTCAAGTCAGCTCACCGTCACCTCGTAAACATTCACCTCCATTTGCAAGTCCCTCCCCGTCCCAGTTACCACCAACCATCATTCCAAGCAACAATATCAGCAGTAGCAGtagcaacaacaacaataataataacaataataacagtAGCAATAGCGGTGGAAGCCCTCCTCAGAGTATTTCACCCACCGTAAAGACAGATGAAGAACCTCAACCTCTCATTGCTACCCCCCGATCTTCATCGACGCCTCCTGGTAAGCCTATTTCTCCAAAAATCTCCAATTCCGGAGAAGCTGTGCATGCCTGTGACTACTGTGGGAAGAAATTCCGCTCCCAGAATAATCTTGAAGTGCATCGAAAAACACATAGTGGAGAGCTTCCGTACAAATGCACCGTCTGCGATCATGCATGTGCGCAAAGTTCGAAACTTAAACGACATATGAAAATACATCGAACGCCGGAAGACCGTACGAGCAACGCCGGATCCGTCGAAACACTCGACGGAGAGGAAAGTGAAGATGAGGAAGAGCTCGACGAAGAGGAAGATGAAGATGACGGCGAaggcgaagaagaagaagctgaAGATTTAAGCGTTCCCAGCCAAGGAAATCCAAAAAACTCGACACAGTCAGCTTCCCTAGTTGGGGAGCTGATGGATAAATTTGGCCTCAGTAACATAGCACAATATAGTGAAGCTTACAAACAAGCTTTGCAAGAATCAGGATCAGCTCTTAAGCTTCATATGGCTAGCAAGGATCGTGATAATAATAACAGTACAAATTTGTCGGCTCAACTAAAGCTGCGCGACGATTTTGCCAAGGGAATATTGCCCGTGCCACCTCCACATCCTTTGCCATTATTTCCCCCATTTGGGGATACATATGATGCCactaaacgtttaaaattaGATCTCGAACGAAATGATTGGTGGTTACCCGGAATTACGAGAGAAAATAAAACGATTCCGGGACCGAGCGCTCTTCTTGCAGGACCGTTTCCAAAGAAGGAGCATTCGCGACGAAACGATACATGTGAATATTGCGGGAAagtattcaaaaactgctcgAACCTCACGGTTCACAGAAGGTCACATACAGGAGAGAAGCCGTACAAATGCGAATTGTGTTCCTACGCGTGTGCTCAAAGTTCCAAATTGACtcgacatatgaaaacacatggTCGTCTCGGGAAAGATGTGTACCGGTGTCGGTTTTGCGAAATGCCGTTTTCGGTCCCGTCCACCCTCGAGAAGCACATGCGTAAGTGTGTGGTAAACCAAGGCAAGAGCCATTTGTTGCCGACTATGCCGATGCTGTCTGGGGACGAAGATTCGTCTACCAGTATCGCCTCCAAGGAGGCTACATGA
Protein Sequence
MTDSDGADPDGHQDILTCGVCQKPFALSDIVRFIQHKVASCNKENFAGGHCFQGADRERDNDDGALPLSTINTRRPSISAPISGKKASGSSTRVHTPPPASPRLPAPGDLCVDGAASSTPKRRASSSPLTSSSLEDGEDVKPNIKQERMEMSSSSEEPSHKKSRTEVADAESNTTNSEPNNYVCSTCKARVHSAWRLVQHVQHSHGVKIYVETSSSSNNNSASSSSSSSSGCSSGGPPPPPSIRHHMLPPPDLHNPFSVGGLLRLPLPPLNHGPVPPAPLFSRPEHHFRMEQLVTEQFRHHGLNLAAAAAAVAAGGVPPPHASFPSPAERPPVVPGVPSRERSTPSQPLSLEPQLDYYSQRLRQLAGTTSPGAAQVSSPSPRKHSPPFASPSPSQLPPTIIPSNNISSSSSNNNNNNNNNNSSNSGGSPPQSISPTVKTDEEPQPLIATPRSSSTPPGKPISPKISNSGEAVHACDYCGKKFRSQNNLEVHRKTHSGELPYKCTVCDHACAQSSKLKRHMKIHRTPEDRTSNAGSVETLDGEESEDEEELDEEEDEDDGEGEEEEAEDLSVPSQGNPKNSTQSASLVGELMDKFGLSNIAQYSEAYKQALQESGSALKLHMASKDRDNNNSTNLSAQLKLRDDFAKGILPVPPPHPLPLFPPFGDTYDATKRLKLDLERNDWWLPGITRENKTIPGPSALLAGPFPKKEHSRRNDTCEYCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRLGKDVYRCRFCEMPFSVPSTLEKHMRKCVVNQGKSHLLPTMPMLSGDEDSSTSIASKEAT