Basic Information

Insect: Cryptocheilus praepositus
Gene Symbol: ZFX
Assembly: GCA_033815515.1
Location: JAWWQZ010000227.1:2185852-2190192[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 1.3 1.4e+02 3.7 0.1 3 23 46 66 45 66 0.94

2 15 3.3 3.6e+02 2.4 3.8 1 23 930 953 930 953 0.81

3 15 0.00011 0.012 16.5 2.7 2 23 1035 1057 1034 1057 0.97

4 15 0.0076 0.83 10.7 0.1 2 23 1070 1091 1070 1091 0.98

5 15 6.5e-05 0.0071 17.2 2.2 2 23 1094 1115 1093 1115 0.97

6 15 0.013 1.4 10.0 0.3 1 23 1121 1143 1121 1143 0.95

7 15 2.5e-05 0.0028 18.5 4.5 2 23 1150 1171 1149 1172 0.95

8 15 0.11 12 7.0 3.7 5 23 1185 1203 1184 1203 0.97

9 15 2.3e-05 0.0025 18.6 1.5 3 23 1210 1231 1209 1231 0.97

10 15 0.01 1.1 10.3 0.3 2 23 1247 1267 1246 1267 0.97

11 15 6.9e-05 0.0076 17.1 0.7 1 20 1273 1292 1273 1295 0.92

12 15 8.6e-05 0.0094 16.8 2.7 1 23 1303 1325 1303 1325 0.99

13 15 0.0024 0.26 12.3 3.2 1 23 1331 1353 1331 1353 0.97

14 15 4.4e-06 0.00048 20.9 3.9 1 23 1359 1381 1359 1381 0.99

15 15 0.0015 0.17 12.9 6.3 1 23 1387 1409 1387 1410 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	1.3	1.4e+02	3.7	0.1	3	23	46	66	45	66	0.94
2	15	3.3	3.6e+02	2.4	3.8	1	23	930	953	930	953	0.81
3	15	0.00011	0.012	16.5	2.7	2	23	1035	1057	1034	1057	0.97
4	15	0.0076	0.83	10.7	0.1	2	23	1070	1091	1070	1091	0.98
5	15	6.5e-05	0.0071	17.2	2.2	2	23	1094	1115	1093	1115	0.97
6	15	0.013	1.4	10.0	0.3	1	23	1121	1143	1121	1143	0.95
7	15	2.5e-05	0.0028	18.5	4.5	2	23	1150	1171	1149	1172	0.95
8	15	0.11	12	7.0	3.7	5	23	1185	1203	1184	1203	0.97
9	15	2.3e-05	0.0025	18.6	1.5	3	23	1210	1231	1209	1231	0.97
10	15	0.01	1.1	10.3	0.3	2	23	1247	1267	1246	1267	0.97
11	15	6.9e-05	0.0076	17.1	0.7	1	20	1273	1292	1273	1295	0.92
12	15	8.6e-05	0.0094	16.8	2.7	1	23	1303	1325	1303	1325	0.99
13	15	0.0024	0.26	12.3	3.2	1	23	1331	1353	1331	1353	0.97
14	15	4.4e-06	0.00048	20.9	3.9	1	23	1359	1381	1359	1381	0.99
15	15	0.0015	0.17	12.9	6.3	1	23	1387	1409	1387	1410	0.96

Sequence Information

Coding Sequence: ATGGATCTCAGCGGCGcgggtggtggtggtagtggtggtccTGCCAGTGGTCCTGCAGCTGCTGTTGCCGGTAGTCCTACCGCGAGTGCTGCTGGAAATGTCGCCTCcgtcggcggtggcggcggtgcTGTGGCATGTCCTGTTTGCACCCTCTATTTACGCGAGGGCATCAGTCTCCAGAGACACTTGGACACGCATCCTAAGGAGCAGGTGATAGAGGCTCTTATCAAAGCGAGCGCTTCCCCGTCAACGCAGCCTCAGGGCCAGCCACAGTTGCAGCTACAGCCACAGTCGCAGCCACAGCCGCAGATTCAACAGAGTCAGCAGTCTACACCTGCGGCGCAACCGACACAACAGTCACCTCCATCTCTGCCTTCGCTTCCGCCTGTAGCTTCTACAGTGCAGTCACCTCAAGGCACCCCTGTTCCTCCCCCACAAGTGACACAAAACATCTCTGCTCAATCTCCATATCCTATAGGACCCATCTTTGAATGCCCACCTATTGGGACTATGATGCCACCTCAGTTTGCCTCCTTCAGTTATCAACAATTTGTCAATAATGGGACCATGATGATACCGCAGTACGCGATGGCCCCACAGGCCAATCAAATGATGCAGATGCTATATAATCCATATGGTATGTACCAGCAGCAGCAAATACCCACTGTTCAAATGATCTCTCCAGTTACTGCAATACCTAGTACGTCCAGAATCAGACCAGTAGTTACCATGGCTGGTGACTCCACCGGTCGAACCACAATTACCGTACCTGTTAATAATTCTGAACCCAAGCAGATATTACCTGAGATTCTACCAGATTCAGACACCAAATCTGAGAGTGACCCGTCTGAATTAAATCTTGAACCTGCGACAACGCAGCAGACAGAGGATGCATCCATGCAACATGAAGAAACCCAAGCTAGTGAGGTTCAAATGGAGCACAGAGGACAGCAGACGCAGAACACTGCAATAACTATAACTTGTGACATAGATGAAGAAAATGCAGAGAGCGTTCTGCCAGATATTGACGATGTGGAGTCAACTAGAGTTGTGGATATTCGTTGTAAGACTCCACGGTACAATCAACTGGATACAAGGCAATTTGCAGAGGGATacagagaggaggagagaaggcttgaaataaatgaaacatctTTTACGATAAATGACGAAAATAAATCGGGTAAGCACGTGACGGACGAGAGATCGCTACAGCGAGACGAATTGTTAACCCAGGAAAACGAATCCAATCCACCTCAAGTTCCTTTAGTAGAAGTAGGTAAGGATTCTTCTCAACCGGAAGTGCAAGAGCAATTGGAGCGTCTACTTTTAACTATAATCGGATCAGAGTTCAACAACGTTCCAGGAAAAGAGCATAATTTGCAGGCGGGTGCTGAGGACAAAGAAAGCACCAAAGAGAGACCATGTTCGGAAAAAGAGGAAAGTATTACAGCAGAGACGGTGGTGATGATATCGTCTCATGAAAATGGTCGTAAGATACCCGACATAGAGGTAAAGATATCGCAGCGGCCGAAGGCTTATGTAGATGACGAACAACAGAAGAATTCTAACCATTTGTATCATTATAAACACAGCGTGTCTGCGCCGTCTTCACCAGTGATGAAGAAAAAATCATATAGAACCTACTCTGTCCGTTCCGAAACTGGATCAAATGAGAATTTAAGTATATGTCGTGCTTCAACTTGGATGGCACTACACGAcgacgaggaagaggaggatGAAGACGAGGAAAAGAACGAAGCGGAAGACAACTTTGACGAGGCGGATATGGAGATTGAGGAAATTCCCAGTCCACATACACCATTTTTAAAGTACGGCGAGCATATGGACAGCGTTCGATCACACACGCCATTATCCGCAATTAGCGGCATTTCCGTATTGCGAGTCCGTACAGACCTTAGCAAACCGTGCTCGCCAGCATCCATTCATTCCTTTTGTCATATGGATGCCGATAGTATGAGCCACGACGAGGAGAGCAACGACGCCGCTGGACTAACGCCAGAGAAAGATCCGATCGATTGTTCTCCAACTGAAGAAACGAAAATCAACGAACAGGCGGTGACCGTGTGCGAGAGCGACAAGAAAGTAGAGTCCCCGGTCTACCATCAGTCCGTGATAACTGAACACGTTAGCGCTTTCCCAGCGATTCATTCCCAACAGCCAGTTCTGATACACGAATCATACTCAATGCCAACAAATAAAACCAATCTCTTGAATCTGTCCGAGTCCGTCGATCCTATGACTAGCACAGAGTCGAAGAGGTTCCACTCGGGCAAGCCGGTCATTCAGAAACAACCGATGGAACTACTTAATATAAATGAGGACGCTCATGCCGGTCCAATGAACGTTTTCGAATTTGACGGACTTCAAATTTTAGTTCCTAGTACATTCATAAGTGAATCATCTCAGAAGGCGGTTAGTGCGACCAGTCAGCAATCTATGGCGAGTAGTGAGGGTGGTGCGGGCATCGATGAAGAAGTGAAGAGTGTCAACATGCGCGCCGATGAGACCATGCCGCCTAGAGGGGAATTGTCTGAGCAAGAGAGTAACGGCTGCACCGAACAATCTGCATGGCAGCTTTACATGGGGCAAGAGTCTTCGCGCATGTCTACCTCGTACGATCTGATGGCCCGTGAGAGTTGGGAAGAGTCCGAAGGTTCGGATAATGAAATTGGCGGTCCTTTACTGGACAGCCGTTCCCTGGCTACGCACTTTACGTCCAGTCTGTTCCTGGATCGCGATCGGAAGACGCCGACAAAGCGGACGTTTAAGTGCTCCCATTGTTCCGAAGTTTTTGATTGTCCAAAAGAGCGTCGAGTTCATAGTACGACCGTACATAAGGAGGCCGGTCCCAGTAGCAGTAGAGATCCGATCGAGCAGCCCGAAGTGAAGGATATCAAACTGCTCGATGGACGCATGAACGTGTTCGACGATATTTTTGTACCGAGTATGCACGTTCAGCAAGTTTATCATCAAGCGCCCCTACTCCACCAACTCCAGCCGCCGCAGCCATCTGACATGACGAAGGTGGAACCCGATCAGAAGATTGAAAACTTAGTTATTCCATCTACGATAGAGGTAACATGTACGATATGCAATCAACGATTTAGTAGTGAGAAATCTCTTCAAATACATCACAGACGAATGCACGTAGCCGAGGTTTCGAAGCGCGTGCGTGAGAATGCCAAATGTCAGATATGCAATGAGGAATTCCCCTCTGTTATCTTGTACAACGCTCATCTGAAGATACATCCGCTGGAATGCGGACAATGCGGCAAATACTTTTACAGGAAGCAAAATTTTAAGCTGCACCTAAAGCGTCATCTAGGCATCAAACCCTTCCCATGTACAGTCTGCGACAAGGCATTCCTCACGAAACAGAAGCTCGACGAGCATACGAACGGTCACACTGGCAATGCTCCCGTAAAGTGCAACTTATGCAACGAGACGTTTCGTAGGTATTCAAATTTAACCCAGCACAAAAATCGACACCACCTCAATATCAAGAAGAAGCTCAAGGACTATATATGCCATTGTGGAGAGGTGTTCCATACGAAGAAAAAATTGGCTTGGCACAAGGAGACGCACGACGAAAAGCCGAAGGCGTGCACCTATTGCAACGAACGATTTATCCACATGGCCAGTCTAACTCGCCATATGCGTCGCGCACACAATCGACGATTTGTGCCGGACGCCCAGAGGGAGAGTGAGAATGTCGAATGTCCGATATGCAAGTGCATCTACCTTAGGTCATCGCTGGCCGTGCATATGCGTGTTCATAACGGCGAACGGCCGTATGAGTGTCAGGTGTGCTCAAAGGCATTCAGCACCAAGTGGAATCTCCAACTGCACAAATGGACTCATGCGGCACGCAGCACGAAACCGTTTAAATGCAATCAGTGCAGTGCTGCGTTCTATCGGCACAGCGATTACACGGCTCATATGAATTCCCATAGAAACGTGCGGCCCTACACCTGCAACTACTGCGGCGCTCAATTCATAAGGAAGTACAACTGCCTACGACATGTCAAAGAACATGAGGAGAACAAGGCGTACACATGTGACGTCTGTAATAAGACTTTCCACAGATCGTATTATCTAAAGGAACATTTACGCGTTCATTCTGGGGCAAGACCGTACACATGCCACATCTGCGGCAAGTCGAGCGGTACCAAATCGAATCACAATAAACACGTCAGGATTCATCATGCGCGAGAACCTGTAAATACCGAAAACTAA
Protein Sequence: MDLSGAGGGGSGGPASGPAAAVAGSPTASAAGNVASVGGGGGAVACPVCTLYLREGISLQRHLDTHPKEQVIEALIKASASPSTQPQGQPQLQLQPQSQPQPQIQQSQQSTPAAQPTQQSPPSLPSLPPVASTVQSPQGTPVPPPQVTQNISAQSPYPIGPIFECPPIGTMMPPQFASFSYQQFVNNGTMMIPQYAMAPQANQMMQMLYNPYGMYQQQQIPTVQMISPVTAIPSTSRIRPVVTMAGDSTGRTTITVPVNNSEPKQILPEILPDSDTKSESDPSELNLEPATTQQTEDASMQHEETQASEVQMEHRGQQTQNTAITITCDIDEENAESVLPDIDDVESTRVVDIRCKTPRYNQLDTRQFAEGYREEERRLEINETSFTINDENKSGKHVTDERSLQRDELLTQENESNPPQVPLVEVGKDSSQPEVQEQLERLLLTIIGSEFNNVPGKEHNLQAGAEDKESTKERPCSEKEESITAETVVMISSHENGRKIPDIEVKISQRPKAYVDDEQQKNSNHLYHYKHSVSAPSSPVMKKKSYRTYSVRSETGSNENLSICRASTWMALHDDEEEEDEDEEKNEAEDNFDEADMEIEEIPSPHTPFLKYGEHMDSVRSHTPLSAISGISVLRVRTDLSKPCSPASIHSFCHMDADSMSHDEESNDAAGLTPEKDPIDCSPTEETKINEQAVTVCESDKKVESPVYHQSVITEHVSAFPAIHSQQPVLIHESYSMPTNKTNLLNLSESVDPMTSTESKRFHSGKPVIQKQPMELLNINEDAHAGPMNVFEFDGLQILVPSTFISESSQKAVSATSQQSMASSEGGAGIDEEVKSVNMRADETMPPRGELSEQESNGCTEQSAWQLYMGQESSRMSTSYDLMARESWEESEGSDNEIGGPLLDSRSLATHFTSSLFLDRDRKTPTKRTFKCSHCSEVFDCPKERRVHSTTVHKEAGPSSSRDPIEQPEVKDIKLLDGRMNVFDDIFVPSMHVQQVYHQAPLLHQLQPPQPSDMTKVEPDQKIENLVIPSTIEVTCTICNQRFSSEKSLQIHHRRMHVAEVSKRVRENAKCQICNEEFPSVILYNAHLKIHPLECGQCGKYFYRKQNFKLHLKRHLGIKPFPCTVCDKAFLTKQKLDEHTNGHTGNAPVKCNLCNETFRRYSNLTQHKNRHHLNIKKKLKDYICHCGEVFHTKKKLAWHKETHDEKPKACTYCNERFIHMASLTRHMRRAHNRRFVPDAQRESENVECPICKCIYLRSSLAVHMRVHNGERPYECQVCSKAFSTKWNLQLHKWTHAARSTKPFKCNQCSAAFYRHSDYTAHMNSHRNVRPYTCNYCGAQFIRKYNCLRHVKEHEENKAYTCDVCNKTFHRSYYLKEHLRVHSGARPYTCHICGKSSGTKSNHNKHVRIHHAREPVNTEN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01255876;
90% Identity: iTF_01255876;
80% Identity: -