Basic Information

Insect: Cryptocheilus praepositus
Gene Symbol: ZNF496
Assembly: GCA_033815515.1
Location: JAWWQZ010000284.1:2360484-2367063[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 30 1.5e-06 0.00017 22.3 3.1 1 23 347 369 347 369 0.99

2 30 3.6e-06 0.0004 21.2 1.1 1 23 375 398 375 398 0.95

3 30 2.5e-05 0.0027 18.5 0.7 1 23 404 426 404 426 0.98

4 30 6.2e-05 0.0068 17.3 0.9 1 23 432 454 432 454 0.96

5 30 0.00022 0.025 15.5 2.9 1 23 460 482 460 482 0.97

6 30 0.00016 0.018 16.0 0.5 3 23 490 510 488 510 0.97

7 30 0.01 1.1 10.3 0.7 1 20 617 636 617 638 0.93

8 30 0.0095 1 10.4 1.7 1 22 708 729 708 731 0.89

9 30 0.00016 0.017 16.0 1.4 1 23 763 785 763 785 0.98

10 30 2.4e-05 0.0026 18.6 1.6 1 23 791 814 791 814 0.97

11 30 1.7e-05 0.0019 19.0 0.4 1 23 820 842 820 842 0.98

12 30 2.7e-07 2.9e-05 24.7 1.1 1 23 848 870 848 870 0.99

13 30 3e-05 0.0033 18.3 0.9 1 23 876 898 876 898 0.98

14 30 6.7e-05 0.0073 17.2 3.5 1 23 904 926 904 926 0.96

15 30 1.1e-05 0.0012 19.6 0.7 1 23 1041 1063 1041 1063 0.99

16 30 3.3e-07 3.6e-05 24.4 0.9 1 23 1069 1092 1069 1092 0.96

17 30 0.0027 0.3 12.1 0.8 1 23 1098 1120 1098 1120 0.98

18 30 6.9e-05 0.0076 17.1 4.0 1 23 1126 1148 1126 1148 0.95

19 30 0.00026 0.029 15.3 5.4 1 23 1154 1176 1154 1176 0.97

20 30 7.6e-05 0.0084 17.0 5.0 1 23 1182 1204 1182 1204 0.99

21 30 0.045 5 8.3 3.0 2 23 1244 1266 1243 1266 0.96

22 30 5.4 6e+02 1.7 0.3 1 13 1271 1283 1271 1294 0.79

23 30 0.019 2 9.5 3.4 1 23 1342 1364 1342 1364 0.98

24 30 0.2 22 6.2 3.5 1 23 1392 1414 1392 1414 0.96

25 30 0.00055 0.06 14.3 2.3 2 23 1421 1443 1420 1443 0.94

26 30 0.00028 0.03 15.2 0.1 1 23 1449 1471 1449 1471 0.98

27 30 0.0005 0.055 14.4 2.3 1 23 1477 1499 1477 1499 0.98

28 30 0.002 0.22 12.5 5.3 1 23 1505 1527 1505 1527 0.97

29 30 6.8e-05 0.0074 17.1 0.1 1 23 1533 1555 1533 1555 0.97

30 30 0.51 56 5.0 6.7 1 23 1561 1583 1561 1584 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	30	1.5e-06	0.00017	22.3	3.1	1	23	347	369	347	369	0.99
2	30	3.6e-06	0.0004	21.2	1.1	1	23	375	398	375	398	0.95
3	30	2.5e-05	0.0027	18.5	0.7	1	23	404	426	404	426	0.98
4	30	6.2e-05	0.0068	17.3	0.9	1	23	432	454	432	454	0.96
5	30	0.00022	0.025	15.5	2.9	1	23	460	482	460	482	0.97
6	30	0.00016	0.018	16.0	0.5	3	23	490	510	488	510	0.97
7	30	0.01	1.1	10.3	0.7	1	20	617	636	617	638	0.93
8	30	0.0095	1	10.4	1.7	1	22	708	729	708	731	0.89
9	30	0.00016	0.017	16.0	1.4	1	23	763	785	763	785	0.98
10	30	2.4e-05	0.0026	18.6	1.6	1	23	791	814	791	814	0.97
11	30	1.7e-05	0.0019	19.0	0.4	1	23	820	842	820	842	0.98
12	30	2.7e-07	2.9e-05	24.7	1.1	1	23	848	870	848	870	0.99
13	30	3e-05	0.0033	18.3	0.9	1	23	876	898	876	898	0.98
14	30	6.7e-05	0.0073	17.2	3.5	1	23	904	926	904	926	0.96
15	30	1.1e-05	0.0012	19.6	0.7	1	23	1041	1063	1041	1063	0.99
16	30	3.3e-07	3.6e-05	24.4	0.9	1	23	1069	1092	1069	1092	0.96
17	30	0.0027	0.3	12.1	0.8	1	23	1098	1120	1098	1120	0.98
18	30	6.9e-05	0.0076	17.1	4.0	1	23	1126	1148	1126	1148	0.95
19	30	0.00026	0.029	15.3	5.4	1	23	1154	1176	1154	1176	0.97
20	30	7.6e-05	0.0084	17.0	5.0	1	23	1182	1204	1182	1204	0.99
21	30	0.045	5	8.3	3.0	2	23	1244	1266	1243	1266	0.96
22	30	5.4	6e+02	1.7	0.3	1	13	1271	1283	1271	1294	0.79
23	30	0.019	2	9.5	3.4	1	23	1342	1364	1342	1364	0.98
24	30	0.2	22	6.2	3.5	1	23	1392	1414	1392	1414	0.96
25	30	0.00055	0.06	14.3	2.3	2	23	1421	1443	1420	1443	0.94
26	30	0.00028	0.03	15.2	0.1	1	23	1449	1471	1449	1471	0.98
27	30	0.0005	0.055	14.4	2.3	1	23	1477	1499	1477	1499	0.98
28	30	0.002	0.22	12.5	5.3	1	23	1505	1527	1505	1527	0.97
29	30	6.8e-05	0.0074	17.1	0.1	1	23	1533	1555	1533	1555	0.97
30	30	0.51	56	5.0	6.7	1	23	1561	1583	1561	1584	0.91

Sequence Information

Coding Sequence: ATGGAGTCGGAAAATTCTGTTGTACTAGAAACTTGCAGGGAAGATGCAATGTTAATACAAACCGTAAAAACTATTGTCACACAGGACAATCAAAATGATTTGGAGAGCGAGGGATTCTTTTTAGTGACGAACGTTCAAGATGACCAACAAAGACACATGGAAGTAGTCGTTCAAGAACCGTGCATGGAAAGTCAGACTGAGGAGAGGATACTGTGGTCGGATCTGTGCAGGGTATGCGCAAATGTCAATGACCATTTGATACCAATATTCGAGGGAGAAGGAATAGAGCATGAATTatgtaacaaaatacataaatatttacctATACAAGTATCTGAAAGCGATACTCTACCCTTACAACTGTGTTATCACTGTGCAGCGACGTTATTAGCTTGGCATGAGCTTGCAGAGGGTTGTTTAAATGCTGAGCGTAGACTCCTAGAGATACAAGAATCATTACATGCAAAGCAACAGTATGTACAACCACCAACGTCAGAGGAAAGGTTACAACGCTCACCACAAGCTATTGCAGTTGTGGCAAATTCCATTGAATCActtccTGTTGCGGAACCGGTTGAGTTAAAAGATGACGGAAGCGGAAGGTCCCCTGCTAACAATACCGATAGGTCCGGTAGTGTCCAGACGTCATTTAAAGTGTTCCTTGATATGCAGAATGTATTTTGGAAACCGTACAAAAGAAAGTGGCAGCTGCAAGAGAAAAAGCCGCCGATAGGAGCCGATTATAATTCAGTATGGATCGCCGTGATGGATTCAACACTGGATCAGCCTGTCATAGCGGCTGACCCGCTGCGCAATAATGAATTTGAGGTGAAAGGGGAGATCTGTAATGACCGGAAAGAGGATATAATGAGAAAGCAAAAGATGCCGCAGCTTACCTCTGGACCAGCAATAGCATCGATCGAGAAGAAAGAAGACATCGCAACAAAAGACCCAATTTATTCTAACAAATTGCAGGATGTTAAGGAATTCAACGCAAACAATGCAGACAACAGTGCGTTTACAGACGTACATGGATCTTATCAATGCGTCGAGTGTGGAAAGTGTTTCAAGCTGAAAGATTCGTACCTGAGGCACATGAGAATACACAGAGATGAACGCCCTTTTACCTGTCACGTGTGCGGCAAGCAATTTCGAGATTCTGGCGGGCTGTCGCGTCATCTCAAAGACGTGCATgcgaaattgaagaattttaCGTGTGATATTTGCGGAAAATCGTTTGCATCAAAAGCGACGAGAGACGACCATCGGCGAACGCATACAGGCGAGAGACCGTATATTTGCGACTCCTGTGGGAAGACTTTCAAATCGAAAGCCTCCCTCTACATTCATAGCAAGCTACACACCGACGAGTTCCCGCATCCGTGCTCGTATTGCAATAAGAAGTTCCGTAGGAGGCAGGAAATGTTAGCGCACGTGACCACTCACACGGGAGAGAAGAATTACGGATGCGACGTGTGTTCGAAGAAATTCCGGGTGAAGTCGGAACTCGTTAGGCATAAACTGGTTCATTCCGAGAGCAAGCCATTCGTTTGCGTCAAGTTTGGCCAACAACGGAAGAAATCCTTTGCTGCATACTGTTCGTCTCATTCTACTACTTTATGCACACAGAATATAACGCAAGCGAACGTCAAGCATCCAATAGTCGAGACGACGGATTCCGATAGTAATGCACGATCAAAAGAAGTGAGCGAAGACGGAAATCCGGAGACTAGCTTCTGCGATAGCGagcatataaatatatcaaaCAGTGCCAACGTTAATTCCACTGACTCATTGTCCTCTGCCACTGAAACTGCAACGAGTACAAAGCGAAGTATTAAGAAGTTCCACACCTGTGTCACGTGTCGTCGTATATACAAAAGAGAATATAATTTACTACGTCATGCGATAAAATGTAAGAAACTCGCGTCCCGAGATAAGGATCCCCTAGATACGGGCGACATCGATGCGCCTATTTTAAGCGATAATCCCATTGAAGCAACGCAGACCGCAATGATTTCGAATGTAAAGACTGAAAGTGTCTGCAGCGAGGCCGCTGGCAACGAAGAAACGAACTCGTGGGGCGAGTTCGACGAAACCACAAGAAAGTCTGGCACCTCTCACCCTTGCATGTACTGTGACTACACAACGAAACGCAAAAAGCTGCTCAAGCTCCACGTCGTCGAATCTCATCCAGAATACGCCGAAAAGAAGCACAAAAAGTTGCGCTGCATAGACAAGGAAGCAGTGTCGCGCGCTCGAATGGAAGTCGACGGCAAGATTTATTACCACTGTAACGAATGCGGGAAGAACCTCTACTCGCCGTACACCTTCTCCTGGCACATAAGGATCCACACCGGCGAACGTCCGTTCACCTGCCATTTGTGCGGCAAGCAATTCCGTGTGAATCAGGGTCTTGCCAGGCACCTGCGCGAAACCCACGCCGGCATAAAGAACTTTCCGTGCGATCTCTGCGGCCGCATGTTCTCGACAAAGCGAAACGCAGAGGATCATAGACGCATTCATACCGGCGAGCGGCCGTACGTTTGTAACGTTTGCGGGAAGACGTTCAAGCAGAAAGCCTCTCTCTTCGTGCACAATCGAACGCACTCGGACGTGTTCCCGTTCAAGTGCAGCTACTGCGATCAAAGCTTCCGCACTCGGCCGCCGCTGATGGTGCACATAACTAAGCACACCGGCGAGAAACCGCACGCCTGTGACGTGTGCGGCCGATGTTTCCGCATAAAATACGAGCTCAAGAGGCATCGTCTCATACACTCCGACGAGAAGCCGTGGCAGTGCACGAGGTACGTAAGTCGAGCCGTGCGATTAGAGGCGGCGTACAAGTCGGATGACGATAAAAGCCGCAGGACACTAAGTGGCCGCGAGCGAGTCGACAAGATTAACGCGCGTACGCACTTAGGTGTCGAATCGAAGAACTGTTGGGCCCCGACGCTGCGTAAGATTCGCGATGCGAACGACAGGCGCGAGGCAGACTCGAAGGAGAATGAGCGCGACGCTAAAGAGGCGTGTGAAAAGCTGACTGCCCGCTCGAAGCGGACACTAGAACAGCACGCTGAAGTGGCACGTTCGAAAACGAGCGTCGACGGATTCACCTATTACAAATGTCGCGACTGCGGCAAAGCGCTCTCGACTGCGTACAATTTCCTAATTCACCGCAACACCCACACCGGCGAAAAGCCGTACACGTGTCACGTCTGCGGAAAGAACTTCCGTTCGGCGTCCGGCTTGAACAGACACGTGCGCGACGTACACACGGGCATAAAGAACTTTCCTTGCGACATTTGCGGCCGTTGTCTCGCGTCGAAGGCCTCGAGGGACGAGCATCGTCGAACGCACACAGGAGAGAGACCGCACGTCTGCGAGACCTGCGGGAAGTCGTTCAAGCAGAAAGCCTCGTTGCACGTTCACAGACTCTTCCATTCGAAAGATCTTCCTCATCAGTGCACGCTTTGCCAGCGCAGCTTCCGACGGAAGCAGGAGCTGGACAagcatattcatattcataccgAGCAGAAACCGTACTCGTGTAACATCTGCGACAAACGCTTTCGCAGCAAGGGCTGCATTAGTCGGCACAAGCGTACCCACAGCAGTCAGAAATCGCACGCCTGCACGCTTTGCGGCGCCAAGTGGCAGATTGAGGCCAACAGCGTCGTACCGACGATCGCGATCCAAGATACGAAAGCGGAGGAAGTGCAGTATGTCGAATGTGCCCACTGCGATACGCATTTCATAGACGTTAAGTGTTTCGTGCAGCACATGAACGTCGAGCACGACGCTCACGCCTATTACTGCTCCTACTGCAAAGCAGCGTATCGCGGCTCGGCCGCGGTATTCCAAGAGCACATGTTGTTTCACAGCACTGCTCATGAAACAACGACAGAGATCGCAGAGAGCGCCGGTAAAgctctgttggagctaaaatgcGAAAATGGGCTAGACATTGTTGACACGGCGAAACAGGAAAACACTTCTGACGTGTCGGGCTCGCAGAAGATCTACACGTGCTACACGTGCGAGGAACGCTTTCTGAAGAAGCATGACCTGAAGAAGCACATAAATGCTCACAAGACAACGAAAGTGATACAGAGCCAAAACGAGGCAGAGTTAGTAAAGCGGGCGAAGCAGGTGATCAACGAACGAATATCTTACTGTTGCGACATATGCAAGAAGCTGATGTTCACCAAGCGAGGCTTTCTGCGTCACATACGCGTGCACACGGGAGAACGACCGTGCAAGTGTGACTTGTGCGGCAAGTGTTACAGAATCGAGCAGGACTTGGCTCGACACATAAGGGACGTGCACGAAGGTCTGAAGAAGTACGTCTGCGATATCTGCGGGCGCGCCTTTGCTAACAAAGGTGCCAAAGACGATCACAGAAGGATCCACACCGGGGAGCGTCCGTACACGTGCGAGCATTGCCCGAAAACCTTCCGCACTCTCAACTCCATTTACATACACAATCGCGTGCACACGAATTACAAGCCTCATAAGTGCTCGTACTGCGGCAAGTATTTTCGAAGTAGACAAAGGCTGAGCAATCATGAGACGACGCATACGGGGGTGAGAGCGTATTCGTGCGAAATTTGTGCTAAGCCGTTTTCGGTCAAAGGCGAACTTATGCGGCACCGCACCATCCACAGTCAGGAGAAGCCGTTCAATTGCCGATGTTGCGACCTCAGATTCGGTCAGAAACGATACTTGCGAAATCATATCAAACAACATCATAGGGAGGAGGCGTCATTGCTGCTGGCAGAATTGAACGAGAAGCGCAATTAG
Protein Sequence: MESENSVVLETCREDAMLIQTVKTIVTQDNQNDLESEGFFLVTNVQDDQQRHMEVVVQEPCMESQTEERILWSDLCRVCANVNDHLIPIFEGEGIEHELCNKIHKYLPIQVSESDTLPLQLCYHCAATLLAWHELAEGCLNAERRLLEIQESLHAKQQYVQPPTSEERLQRSPQAIAVVANSIESLPVAEPVELKDDGSGRSPANNTDRSGSVQTSFKVFLDMQNVFWKPYKRKWQLQEKKPPIGADYNSVWIAVMDSTLDQPVIAADPLRNNEFEVKGEICNDRKEDIMRKQKMPQLTSGPAIASIEKKEDIATKDPIYSNKLQDVKEFNANNADNSAFTDVHGSYQCVECGKCFKLKDSYLRHMRIHRDERPFTCHVCGKQFRDSGGLSRHLKDVHAKLKNFTCDICGKSFASKATRDDHRRTHTGERPYICDSCGKTFKSKASLYIHSKLHTDEFPHPCSYCNKKFRRRQEMLAHVTTHTGEKNYGCDVCSKKFRVKSELVRHKLVHSESKPFVCVKFGQQRKKSFAAYCSSHSTTLCTQNITQANVKHPIVETTDSDSNARSKEVSEDGNPETSFCDSEHINISNSANVNSTDSLSSATETATSTKRSIKKFHTCVTCRRIYKREYNLLRHAIKCKKLASRDKDPLDTGDIDAPILSDNPIEATQTAMISNVKTESVCSEAAGNEETNSWGEFDETTRKSGTSHPCMYCDYTTKRKKLLKLHVVESHPEYAEKKHKKLRCIDKEAVSRARMEVDGKIYYHCNECGKNLYSPYTFSWHIRIHTGERPFTCHLCGKQFRVNQGLARHLRETHAGIKNFPCDLCGRMFSTKRNAEDHRRIHTGERPYVCNVCGKTFKQKASLFVHNRTHSDVFPFKCSYCDQSFRTRPPLMVHITKHTGEKPHACDVCGRCFRIKYELKRHRLIHSDEKPWQCTRYVSRAVRLEAAYKSDDDKSRRTLSGRERVDKINARTHLGVESKNCWAPTLRKIRDANDRREADSKENERDAKEACEKLTARSKRTLEQHAEVARSKTSVDGFTYYKCRDCGKALSTAYNFLIHRNTHTGEKPYTCHVCGKNFRSASGLNRHVRDVHTGIKNFPCDICGRCLASKASRDEHRRTHTGERPHVCETCGKSFKQKASLHVHRLFHSKDLPHQCTLCQRSFRRKQELDKHIHIHTEQKPYSCNICDKRFRSKGCISRHKRTHSSQKSHACTLCGAKWQIEANSVVPTIAIQDTKAEEVQYVECAHCDTHFIDVKCFVQHMNVEHDAHAYYCSYCKAAYRGSAAVFQEHMLFHSTAHETTTEIAESAGKALLELKCENGLDIVDTAKQENTSDVSGSQKIYTCYTCEERFLKKHDLKKHINAHKTTKVIQSQNEAELVKRAKQVINERISYCCDICKKLMFTKRGFLRHIRVHTGERPCKCDLCGKCYRIEQDLARHIRDVHEGLKKYVCDICGRAFANKGAKDDHRRIHTGERPYTCEHCPKTFRTLNSIYIHNRVHTNYKPHKCSYCGKYFRSRQRLSNHETTHTGVRAYSCEICAKPFSVKGELMRHRTIHSQEKPFNCRCCDLRFGQKRYLRNHIKQHHREEASLLLAELNEKRN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01255838;
90% Identity: -
80% Identity: -