Cpri015680.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Cryptocephalus primarius
Gene Symbol
ZFHX3
Assembly
GCA_963576515.1
Location
OY754950.1:4249459-4266350[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 19 0.83 48 4.9 0.3 2 23 164 186 163 186 0.94
2 19 0.00041 0.024 15.3 1.8 2 23 331 353 330 353 0.95
3 19 0.0001 0.0059 17.2 0.7 1 23 385 409 385 409 0.92
4 19 0.015 0.87 10.4 0.4 1 22 451 472 451 475 0.91
5 19 0.82 47 4.9 1.4 1 23 724 748 724 748 0.91
6 19 0.0024 0.14 12.8 0.4 1 23 864 887 864 887 0.95
7 19 0.05 2.9 8.7 2.2 2 22 972 992 972 995 0.90
8 19 0.36 21 6.0 1.3 3 23 1009 1032 1007 1032 0.87
9 19 0.007 0.4 11.4 1.6 1 23 1050 1072 1050 1072 0.97
10 19 0.0015 0.087 13.5 0.7 2 23 1079 1101 1078 1101 0.94
11 19 0.0004 0.023 15.3 3.1 1 23 1209 1233 1209 1233 0.92
12 19 0.012 0.69 10.7 0.6 1 22 1253 1274 1253 1277 0.89
13 19 0.0024 0.14 12.9 0.2 1 23 1326 1350 1326 1350 0.93
14 19 0.019 1.1 10.0 0.0 2 21 1413 1432 1412 1433 0.94
15 19 0.7 41 5.1 2.5 2 19 1563 1580 1562 1585 0.90
16 19 0.00025 0.015 15.9 2.5 1 23 2161 2183 2161 2183 0.99
17 19 0.001 0.059 14.0 0.3 1 23 2277 2299 2277 2299 0.98
18 19 0.01 0.6 10.9 0.4 2 23 2448 2470 2447 2470 0.97
19 19 0.91 53 4.8 3.3 3 23 2732 2754 2730 2754 0.89

Sequence Information

Coding Sequence
ATGCCCACTCTGTCCGCGGCGCCTGAGCAGAGTCCCGGCGGCCGCCGCACCGACCGGCAGAACACAAAACACACACCGGACGCCATGAGCCCCGAGCAGGAGGCGAGTCCCCCCCCTGCCGCACCGGGCGCATCGTCACCACCGCCGCCACCTGCGGGGCCCCCGACGCGGATCCCTTCGCCCGCAATGTCCCACCAGGAGAACAACTCCGACGTGGAGCAGTTCGCCGGTAAGATAGTCTACAATCCGGACGGTTCCGCGTACATCATCGAGGACTCGGAGAGCGACGGGGAGGGCCACGGCCACGGCCTCGGCAACACGACGTCGGTGCCTGAGATAGTACCACCGCTCCAGGCCGTCTACGTTTCGAGGCTCATGCGCCAACCTACGCGACCTACTGAACTGCCCGCAGTCCATAGTTACCGCGTCGTCGCGCTAAGGGACGCTCGGCCCCCGAGGCCCGCTTCCGTGCCAGTAAAGCCCATCCTGATGTGTTTCGTCTGTAAACTGAGCTTCGGTTTCGCTCGGTCGTTCGCTAACCACGCACAATCCGAGCACGGGGTCAGTTTGTCGGAGAACGAGCGCGAAGTGCTCGCAGCCGATTGCTCGGCGATCTTGCAGTGCGTCGGCGCCGAGAAGAGGCCGATGGTCTCGCTGCTCGAGCCGCTCGGCGCGGCGCCGCTCGACAACCACAACTCAAATCAAATAGTTCCTGTTCATCCTGTACAAAATCGCAACGAAGGACCCTCGCCGATCACCGAAACGCCGCCATGTTCCTCATCTCGTAACACGCCCGGAAAATCACCATCCCCGCCTTTTGTGGCACCGCCTGCCTTCATGACCGGCACCACGATAGGTGTCTGCCCGGAGCACCTCCAAGGGAGACCGTCGGGCGTCGAATGCGCCCGCTGCGAAATGATCCTCGCCTCGGGCAGACTCGGGCCCGCCGGCCTGGCCAACGTTCACAGCAGGAACTCCTGCAAAACACTCAAATGCCCCAAGTGCAACTGGCATTACAAGTATCAAGAGACGCTCGAGATACACATGAAAGAGAAGCACCCCGAAGCGGAAACGAGCTGCATCTACTGCATAGCCGGTCAGCCTCATCCTCGGTTAGCGCGAGGCGAGACGTACACCTGCGGGTACAAACCGTACCGTTGCGAAGTATGCAACTACTCGACGACTACCAAAGGCAACCTTAGTATACACATGCAATCCGACAAGCATCTCAATAACATGCAAGAGCTCCAGAACGGTGGAGCGCCGAACACGGAATCTCGACAAGCGTCACCTAAAGCACCTCCCTTGCATCACTCCCCGGTGAGCAGCGGCCACAAACCGAAACCCAGCTTTAGGTGTGACGTGTGCAATTACGAGACCAACGTGGCAAGGAACCTGAGAATACACATGACATCCGAAAAGCATACCCATAACATGCTGGTGCTTCAGCAAAACGTCAAGCACATGCAGACCCTCTCGGCGTTGCACCACCAACAGCACCCTCAGCAACACATGGACAGTTTGTACGGCATGTATCCCGGCCTCGGCGATAAACCCGAAGCCGCCCTGGCCGATATGGCTTACAACCAGGCGTTACTGATCCAAATGATGACCGGAGGTCAGCTGCCGGGCCACGGGGGTCCCGCCGACATGTCTGCCCACTCCGACCTCGGTTTGAACCCCGAGACGATGGAACCGCCGCCGGAACCGGCAGATCCGGACCCGGAAAAGACTTATCAGTGTTGTGTGTGCAACATTTTCCAGACCGATAATTTGGAAGAACTCGGGCGACACCTGGCGATGGACCGAACGCGGCTGAGGGAACAAGAAATCCTCGCGGTCGTAGCCGGTCATTACGTTTGTAAATTATGCACATATAAAACGAATCTGAAAGCCAACTTCCAACTCCATTGTAAGACTGATAAACATCTCCAGAGACTGCAGCACGTCAACCATGTGAAAGAAGGTGGACCACGTAACGAGTGGAAGCTAAAGTACGCTTCGGCACCTGGAGGAGTTCAAATTAGGTGTAGCGCCTGTGATTACTACACCAATTCCGCACACAAACTGCAACTGCACGCCGCCGCCGGCCGCCACGACGCGGGAGTCGCGTTACTGAAGCACCTTTTAGAAAGGTGTTCCACGCTAAGTCCAAATCAAGCCAGGGTATTTCATTGCTCACTTTGTGGGTTCTCCTCTACGAATAGACTACCTCTCTTACAACACGTACGATCTCTAAAACACCTCCATATGGAACAACTCCACCAACTGCAGAGGCGCGCCGAGGGCAAGGATAACGCTCCGGAAATAGGAGAAGTTTTCCACGTCGTACCTGGGCCCACCGAACAAACTTCGCATACGCCAGAGCGCAGAGATAGTATCAACTCGGAGCTGAGTCAGATCGACGTTAACAGAGATCAAGTGAAATCGGAGCCTCGGGACGATGGGGAGGACGCGAACAACAGCGAAAACAGCTCGCCTCAGCACATGTGCCCTTTCTGCGAGTACAGCAGCGATTCTGAGATGCGCATCCAAGCACACGTGCTCGCTCAGCACGGTACGAACAACGCGCCCATGCCCGAGGTCGCTTACAATTGCCCGCTCTGTCAGGACTCTTTCAAAGACCGCACGACGCTCGAACGTCACGTCATGCAGATACATTCCGTCAACAGCGAGGGTCTGCAGCGGTTGCTCATGCTAGTGGATCAGAGTCATTGGTTGAATCAAGCCTCTAGGACGCCTACTCCGAATAATTCTTTGAATCAGTCTCAAACGACGCCTAATCAGATCGTGTCACCGACTTCTGTGTCTTCCAAAGATTCTAATAAGTTCGAGAAGAGCGATCCTAGCCAGGACCACGATCCTGATATACTCTCCCCTAGCAGTGACGATACGGGCGAAATGGAGTCGGAACGTTGCGGCACGTGTTTCAAGACGTTTCGGAACATCGACGAATTGTGTTACCATCAGAACGAGACCGGCCACCTGGAGATCAAACAGACTCCCAGCGGACCCGGTTATCTGTGCTGGAAGAAGGGGTGCAACCAGTTTTTTCCTACGGCGCACACCTTACAAATGCACTTTAAGGAGGTGCACGCTAAAAACTCCATCGCAAACATGTCGGTTTCGGAGAAACACGTATACAAATACCGCTGCAATCAGTGCTCGTTAGCGTTTAAAACACTAGAAAAACTGCAGTTGCACTCGCAGTACCACCTAATTAGAGACGCGACGAAATGCGTTCTGTGTGGTCGCAGCTTTAGATCGCTCGTGGCGCTGCATAAACACGTCGAGAGTGTCCATTCCGAGTTGACCGATGAAGAATTGAGCGCCTACAAACAGAGCCTAATGAACAATCCTTTACTGTTGGCAGGACTCCAAGGACAAGTACTCGACAGTTCCACGAACGAGATCCTCAAAAAGGAATCGATGCGAAGCGAAGACGAATCCGGCGAATGCGACGACAGCAAAGAAGTAAACACTAGTCAGTCGTTGGAGGAGGCCAATCAGAACGATGGTGAAAATTCTGACGACAGTATTATTTACAAAGACCAGCAGTTCTTAGAAGATTACCTAAATAGCCAGGCCATCGCCGAAGACAGCTACAACGACCCGAATAGGAAGTACAAATGCCACCGCTGCAAAGTGGCCTTTACAAGACAAAGCTATTTAACGGCCCACAATAAAACTCTTTTGCACCGGAAAGGCGAGAAACTGAGTTATCCCATGGAGAAATATTTAGACCCTAACCGGCCGTATAAATGCGACGTGTGCAAAGAGAGTTTCacccagaaaaatattttattagttcaTTACAATTCGGTGAGTCACTTGCATAAGTTGAAGAGAGCGATGCAAGAGCAACAGAACAATAACAACAATTCGCCCGTGTCGCCGATCGCCGGCATGACACAAGCGCAGAATTTAACTCTAACCCCGAAGAGCAGCTCGAGCGAGGAGGACGACAAGAAAAAGTACCGTTGTAACATTTGTAAGGTGGCGTACACGCAGGGTAGCACGTTAGACATCCACATGCGGAGCGTTTTGCATCAGACGAGGGCCAGTAAATTACAAGACCTCGCGTTGGCCGGTCAGATCGACTTGACGAAGCCGTTGATCGAGCAACCCGAAGCCATGCAGTCTCCGAAGCAAACGAGCCCGGCGCCAGGTAGTGGGGACAAGCAACCCTCTCCCACCCCTCCGTCGCCCGGGGTCTCAGGTAGTCAAGGGATGACGAGCTGCCCTAAGTGCGGCGCGTTATTCGGTTCGCAAGATCAGTTGAGCGCCCATCAGCAGCTGTACTGCATGTTCGCACCGCCTATGGCGATCTTTCAAGGTGCTCCGGAGCCGGGTCAAGCGAAGAGTCCGCCACCGTCCGGCGAGTCGCAGGAGGGCGTCCGATTGAATTTGCCGAAGAAGTCCGGCTCGCACATGTACAAGCATTTGCTCGAGAGTTTCGGTTTCGATTTAGTGATGCAATACAATGAAAGCCACCAGAGGCGACAGCGACAGCAACGCGAGGCGGAAGAGAAAGCCGCCCACGAGAGCCACACTCCACCACCACCGGCAACGCAACAAGGCCCCGAAGAGCAGAGCAACAACGAAAACCTCGCGAACGCGGAAACGGCTCCGGACCCGAAAGCCGAGGACGATCCGGAGACCAGCCTGCCCGAAGTAAGTAAATCCACGTGCCAACATTGCAATAAAGAATTCTCTAGTGTGTGGGTGTTGAAGTCACACTGTGAGGAAGTTCACAAAGACCTTGTGCCGCTCGAATTCTTAGAAAAGTATGCTCAACAGTTCAAAAACGAATACGAAAAGAAATCGGTGGTGGTGACGGCGGCGACTTCCTCGACCAATAACACATTACCGAGGTCCTCTACGCCCGGCGGCgcgacgccgacgacgacggCCGCCGCCGCCCCGCCGGCCGCCTCCTCCTCGTCGAGCCCCCTCGATAACGCCACCCCCGAGAAAGACGACGAATCCAAAGAGCTCTTGCACGCGAAACTGAACTTGCAAACGCCGCCGGAGGCGACCTCCACGGCGCCCTCGACGCCGACCTCCTCGACCACGCCGGCCAGCAGCACGGACTCCCTCCCGGCCAACATCCAGGCCATGATAGCCCAGAGCATGGCGCAGAACCCGATGGCCTTGGCGCAGCAAATGTCCGAGATGCAGGCCGCCTTGAACGTCATGCAACTGCAGCAGTTGAATTTCAATCCGATGATGCAGATGATGGGAATGGGCCTGCCGTTGGGGCTCAACGCCTTGGCCGCCATGAACTTGCAGCCGCCCTTGGTGCCGCTCATGATGCCGCCCCCGCCCTACGATCCGATATCGCAGTTCGGGCCGCAGGACCAGCAGGCCATTATGGCCAAACAGCAAGCGATGATGCAGCAACAAGTGGCCGTCAACGCCGCCGCCAACCAGAAGCGCGCCAGGACTCGCATCACCGACGACCAGCTGAAAATTTTACGGGCACATTTCGACATCAACAACTCGCCTTCCGAGGAGCAGATCCACGAGATGGCGGCCCAGAGCGGCCTGCCCCCCAAGGTGATTAAGCACTGGTTCCGCAACACCCTGTTCAAGGAGAGGCAACGCAACAAGGACAGCCCTTACAACTTCAACAATCCGCCGTCGACCACGCTCAACCTGGAGGAATACGAAAAGACCGGAGAGGCGAAAGTGATGCCGTTGAATAGCTCGGGGAGCAGCACCGAAGAGAACAAACAGAAGGAGTCTCCCATGCATGTCAGTCAGGAGATTAAAAGCGAAATGAAAGACGAAGCAGTCGATGAACCAACAAAATTTAACGAGGATAAACCTCAAGAAAGCAACGACGAAAAACCTAATATGTTTAATTTACCGCTCAATTTACAACCGCCGCAGAGTCCCGCTACTTCTGTGGCTGGATCCGATAACCAGAACGTGTCGCAGCCCAGCACTCCTAACAGCCTTACTCTCACTTCGATCATCGCCTCTCAGCTCGGTGACACCTTGACCACCAGCACCCCCTCGATGAACATGACGAACATCTCGACTCACCACGGAATGACGAGTCCGATGCTGCCGCCGCCAAAATTAAACCAGCAGAATTTCTCCACCCCGAACAATCTACAAGGGATGCTTCCGCTGACCCCGAACCGCTGCTTGAGCCCGAGCCGGGAATACAGCAACCCCGGTAGTCAGTCTTCTAGCGGATCGACTGGGAAACGAGCGAATCGAACCCGATTCACCGACTATCAGATCAAAGTCTTGCAGGAATTCTTCGAAAACAACGCCTACCCTAAAGACGACGACCTGGAATACTTATCCAAGCTACTAAACCTTAGCCCTAGGGTGATCGTCGTATGGTTTCAGAACGCCCGCCAAAAGGCTCGCAAGGTTTACGAGAACCAACCAGCCGCCGAGCCCATCCCCGGCATTCCCGAAGAGAGCGGCGCAAACAGATTTCAAAGGACCCCCGGTCTCAACTACCAATGCAAAAAATGCCTGTTGGTGTTCCAGAGATACTACGAACTAATTCGCCACCAAAAGACGCACTGTTTCAAAGAGGAAGACGCGAAGAGATCCGCTCAAGCCCAAGCTGCCGCCGCGCAGATCGCCGCCGTTTTGAGCTCCGAAGATTCCAACTCCAGCACCACCGTCGAACAAACTCAACCCCAGCAACACCCCCTTCCTCAACCTCCTAACATGCAACCCGGCAGCCAATCCAACACTCTACACAGTCCCTCACAACCGAATCAGTCGACGACACCGACTCCTACTCAAGGAAATTTTCCGCCCACGTCGCCCTCGCCCTCCGAATCTAAGGACAGCACATTTCAATGCGACAAGTGCAATTTAGTATTCCCCAGATTCGATCTGTGGAAGGAGCACCAACTGGTGCATTTGATGAATCCCAATCTTTTTCCGTCATACCCGCCGGATTCCCCATTCGGAATCCTACAGCAGCACGCGCAGCTTCAACAGTTGAACGCAAACCTGGGCGATCTCACCAAACAACCGAACAACCTCGCCCCGAACCTACAGCATCCGTTGATCAATATGTTGAACAACGTCGCTGGCCAAAAGAGGAAGATCGACGAATTCGACGGAGAAAGTGACACGTCCGATCAACCGAAGGACAAAAGACTGCGAACGACTATTTTGCCAGAACAGCTAGATTACTTATACCAAAAGTATCAGATAGAAAGCAACCCTTCTAGGAAGATGTTGGAGAATATCGCCCGAGAAGTCGGATTAAAAAAGCGGGTCGTGCAAGTGTGGTTCCAGAACACCCGGGCCAGAGAACGAAAGGGACAATTCCGGGCTCACGCTCAGGTGATTAACAAACGTTGCCCGTTCTGTCCGGCACTCTTCAAAGTAAAATCCGCTCTGGAATCTCACCTGTCCACCAAACATGCCGACCAGTGCGCCAGGGGCGAGATCAACATCGACGCACTGCCCGATGAGGAGGCCAGCCTCGAGTCTGCGCCGAGTTTGAGTTCCGGCAGCGAGAATAAATTCCAACAGCAGAACCCGAACATGATGCCGCCGCTTTTCCCCACTCTACACCCGGAGATGGAGAACTCGTTAAAGAAACTTTACGAGGAGAGCATGAAGAGATACATGAGCGAAATGCAGGCCCATGCCTCCTCGTCGAACGGCGATAAAAGCGAAATAAAATCGGAAAAGGGCGAAGGGGGCGAAATTCCCTTAGATCTCTCCAAACCCGTAGACTTATCGAGACCGATGAAAGTATCAATGGATCACGAGCGCAACATGTGCGATCCCGGTCCACTAACTGATCTCAGCGAACGATCACTTTGCGACGAAAGAAGCGATACGATGTCAGAGACGACGGAGTTTTTTGACGACGAGAGCAACCCGACCTCTCCGGCCAGCAGCACCCACAGCAACACCCAGAGAGCGATGAATAACAGCGGAGGCTCGTCTGCGGGCGGCTCTAAGCGTTTCCGCACCCAAATGTCCTCGGTGCAAGTCAAAGTGATGAAGATACTGTTCAACGACTACAAGACGCCGACGATGGCGGAATGCGAGAGCCTCGGCAGAGAGATCGGGCTGCCCAAGCGGGTCGTCCAGGTCTGGTTCCAGAACGCGAGAGCTAAGGAGAAGAAGAGCAAGATGGCGCTGCAGAAGGCCCTCGGCCAGACCGAACCCGAGAACCCGCCGATGCCGGACGATTGCAAGTTCTGCAACTTCAAGTACTCGCACAAGTACTCGATCCAAGACCACATCTTCACGAAGACCCACATAGCCAACGTGAGGATGCACCTCGAGAACCAGAACAAGGAGAGCGGCACGGAAGGCGAGTTCACGGTGCCGCCGCTGCCGGGAGCCTCCGGTTCCATCAACGCCGACTCCACCACGAATCCCCAGCAGAACATCAACAACAACACCCACCTGCAGCTCCTGCAGATGGCCGGCATGCAGATGGGCGGCGCGTCGAAGGGCGGCGAGCAGGAGGAGAACCAGGAGAGTCTGTTCCAGCAGCTCTACGCTCTGGGGAACAACGCCAACTTCGGGGTGCAGAACCAGTACGTCCATCACGCGATGTTCGGTGCTAATGGTGAGTACCATTTTTTCACGTAG
Protein Sequence
MPTLSAAPEQSPGGRRTDRQNTKHTPDAMSPEQEASPPPAAPGASSPPPPPAGPPTRIPSPAMSHQENNSDVEQFAGKIVYNPDGSAYIIEDSESDGEGHGHGLGNTTSVPEIVPPLQAVYVSRLMRQPTRPTELPAVHSYRVVALRDARPPRPASVPVKPILMCFVCKLSFGFARSFANHAQSEHGVSLSENEREVLAADCSAILQCVGAEKRPMVSLLEPLGAAPLDNHNSNQIVPVHPVQNRNEGPSPITETPPCSSSRNTPGKSPSPPFVAPPAFMTGTTIGVCPEHLQGRPSGVECARCEMILASGRLGPAGLANVHSRNSCKTLKCPKCNWHYKYQETLEIHMKEKHPEAETSCIYCIAGQPHPRLARGETYTCGYKPYRCEVCNYSTTTKGNLSIHMQSDKHLNNMQELQNGGAPNTESRQASPKAPPLHHSPVSSGHKPKPSFRCDVCNYETNVARNLRIHMTSEKHTHNMLVLQQNVKHMQTLSALHHQQHPQQHMDSLYGMYPGLGDKPEAALADMAYNQALLIQMMTGGQLPGHGGPADMSAHSDLGLNPETMEPPPEPADPDPEKTYQCCVCNIFQTDNLEELGRHLAMDRTRLREQEILAVVAGHYVCKLCTYKTNLKANFQLHCKTDKHLQRLQHVNHVKEGGPRNEWKLKYASAPGGVQIRCSACDYYTNSAHKLQLHAAAGRHDAGVALLKHLLERCSTLSPNQARVFHCSLCGFSSTNRLPLLQHVRSLKHLHMEQLHQLQRRAEGKDNAPEIGEVFHVVPGPTEQTSHTPERRDSINSELSQIDVNRDQVKSEPRDDGEDANNSENSSPQHMCPFCEYSSDSEMRIQAHVLAQHGTNNAPMPEVAYNCPLCQDSFKDRTTLERHVMQIHSVNSEGLQRLLMLVDQSHWLNQASRTPTPNNSLNQSQTTPNQIVSPTSVSSKDSNKFEKSDPSQDHDPDILSPSSDDTGEMESERCGTCFKTFRNIDELCYHQNETGHLEIKQTPSGPGYLCWKKGCNQFFPTAHTLQMHFKEVHAKNSIANMSVSEKHVYKYRCNQCSLAFKTLEKLQLHSQYHLIRDATKCVLCGRSFRSLVALHKHVESVHSELTDEELSAYKQSLMNNPLLLAGLQGQVLDSSTNEILKKESMRSEDESGECDDSKEVNTSQSLEEANQNDGENSDDSIIYKDQQFLEDYLNSQAIAEDSYNDPNRKYKCHRCKVAFTRQSYLTAHNKTLLHRKGEKLSYPMEKYLDPNRPYKCDVCKESFTQKNILLVHYNSVSHLHKLKRAMQEQQNNNNNSPVSPIAGMTQAQNLTLTPKSSSSEEDDKKKYRCNICKVAYTQGSTLDIHMRSVLHQTRASKLQDLALAGQIDLTKPLIEQPEAMQSPKQTSPAPGSGDKQPSPTPPSPGVSGSQGMTSCPKCGALFGSQDQLSAHQQLYCMFAPPMAIFQGAPEPGQAKSPPPSGESQEGVRLNLPKKSGSHMYKHLLESFGFDLVMQYNESHQRRQRQQREAEEKAAHESHTPPPPATQQGPEEQSNNENLANAETAPDPKAEDDPETSLPEVSKSTCQHCNKEFSSVWVLKSHCEEVHKDLVPLEFLEKYAQQFKNEYEKKSVVVTAATSSTNNTLPRSSTPGGATPTTTAAAAPPAASSSSSPLDNATPEKDDESKELLHAKLNLQTPPEATSTAPSTPTSSTTPASSTDSLPANIQAMIAQSMAQNPMALAQQMSEMQAALNVMQLQQLNFNPMMQMMGMGLPLGLNALAAMNLQPPLVPLMMPPPPYDPISQFGPQDQQAIMAKQQAMMQQQVAVNAAANQKRARTRITDDQLKILRAHFDINNSPSEEQIHEMAAQSGLPPKVIKHWFRNTLFKERQRNKDSPYNFNNPPSTTLNLEEYEKTGEAKVMPLNSSGSSTEENKQKESPMHVSQEIKSEMKDEAVDEPTKFNEDKPQESNDEKPNMFNLPLNLQPPQSPATSVAGSDNQNVSQPSTPNSLTLTSIIASQLGDTLTTSTPSMNMTNISTHHGMTSPMLPPPKLNQQNFSTPNNLQGMLPLTPNRCLSPSREYSNPGSQSSSGSTGKRANRTRFTDYQIKVLQEFFENNAYPKDDDLEYLSKLLNLSPRVIVVWFQNARQKARKVYENQPAAEPIPGIPEESGANRFQRTPGLNYQCKKCLLVFQRYYELIRHQKTHCFKEEDAKRSAQAQAAAAQIAAVLSSEDSNSSTTVEQTQPQQHPLPQPPNMQPGSQSNTLHSPSQPNQSTTPTPTQGNFPPTSPSPSESKDSTFQCDKCNLVFPRFDLWKEHQLVHLMNPNLFPSYPPDSPFGILQQHAQLQQLNANLGDLTKQPNNLAPNLQHPLINMLNNVAGQKRKIDEFDGESDTSDQPKDKRLRTTILPEQLDYLYQKYQIESNPSRKMLENIAREVGLKKRVVQVWFQNTRARERKGQFRAHAQVINKRCPFCPALFKVKSALESHLSTKHADQCARGEINIDALPDEEASLESAPSLSSGSENKFQQQNPNMMPPLFPTLHPEMENSLKKLYEESMKRYMSEMQAHASSSNGDKSEIKSEKGEGGEIPLDLSKPVDLSRPMKVSMDHERNMCDPGPLTDLSERSLCDERSDTMSETTEFFDDESNPTSPASSTHSNTQRAMNNSGGSSAGGSKRFRTQMSSVQVKVMKILFNDYKTPTMAECESLGREIGLPKRVVQVWFQNARAKEKKSKMALQKALGQTEPENPPMPDDCKFCNFKYSHKYSIQDHIFTKTHIANVRMHLENQNKESGTEGEFTVPPLPGASGSINADSTTNPQQNINNNTHLQLLQMAGMQMGGASKGGEQEENQESLFQQLYALGNNANFGVQNQYVHHAMFGANGEYHFFT