Basic Information

Insect: Cryptocephalus primarius
Gene Symbol: KLF2_2
Assembly: GCA_963576515.1
Location: OY754956.1:5937025-5939587[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 4.2e-05 0.0025 18.4 5.8 1 23 106 128 106 128 0.98

2 18 6.9e-07 4e-05 24.0 3.7 1 23 134 156 134 156 0.95

3 18 1.4e-07 8e-06 26.2 3.8 2 23 163 185 162 185 0.95

4 18 1.4e-07 8.3e-06 26.2 3.0 1 23 191 213 191 213 0.99

5 18 1.5e-07 8.8e-06 26.1 1.6 1 23 219 241 219 241 0.98

6 18 3.5e-07 2e-05 24.9 1.5 3 23 249 269 247 269 0.98

7 18 1.7e-05 0.00097 19.7 0.7 1 23 275 297 275 297 0.98

8 18 6.6e-06 0.00038 20.9 2.0 1 23 303 325 303 325 0.98

9 18 5.2e-05 0.003 18.1 3.5 1 21 331 351 331 352 0.94

10 18 2.8e-08 1.6e-06 28.4 3.6 1 23 459 481 459 481 0.98

11 18 9.8e-06 0.00057 20.4 0.8 3 23 489 509 487 509 0.98

12 18 5.5e-08 3.2e-06 27.5 1.8 1 23 515 537 515 537 0.98

13 18 3.2e-06 0.00018 21.9 1.8 1 23 543 565 543 565 0.98

14 18 0.00011 0.0065 17.0 1.4 1 23 571 593 571 593 0.99

15 18 1.1e-07 6.1e-06 26.6 0.2 1 23 599 621 599 621 0.98

16 18 3.8e-07 2.2e-05 24.8 1.0 1 23 627 649 627 649 0.97

17 18 6.4e-07 3.7e-05 24.1 0.2 1 23 655 677 655 677 0.97

18 18 4.4e-07 2.5e-05 24.6 0.6 1 23 683 705 683 705 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	4.2e-05	0.0025	18.4	5.8	1	23	106	128	106	128	0.98
2	18	6.9e-07	4e-05	24.0	3.7	1	23	134	156	134	156	0.95
3	18	1.4e-07	8e-06	26.2	3.8	2	23	163	185	162	185	0.95
4	18	1.4e-07	8.3e-06	26.2	3.0	1	23	191	213	191	213	0.99
5	18	1.5e-07	8.8e-06	26.1	1.6	1	23	219	241	219	241	0.98
6	18	3.5e-07	2e-05	24.9	1.5	3	23	249	269	247	269	0.98
7	18	1.7e-05	0.00097	19.7	0.7	1	23	275	297	275	297	0.98
8	18	6.6e-06	0.00038	20.9	2.0	1	23	303	325	303	325	0.98
9	18	5.2e-05	0.003	18.1	3.5	1	21	331	351	331	352	0.94
10	18	2.8e-08	1.6e-06	28.4	3.6	1	23	459	481	459	481	0.98
11	18	9.8e-06	0.00057	20.4	0.8	3	23	489	509	487	509	0.98
12	18	5.5e-08	3.2e-06	27.5	1.8	1	23	515	537	515	537	0.98
13	18	3.2e-06	0.00018	21.9	1.8	1	23	543	565	543	565	0.98
14	18	0.00011	0.0065	17.0	1.4	1	23	571	593	571	593	0.99
15	18	1.1e-07	6.1e-06	26.6	0.2	1	23	599	621	599	621	0.98
16	18	3.8e-07	2.2e-05	24.8	1.0	1	23	627	649	627	649	0.97
17	18	6.4e-07	3.7e-05	24.1	0.2	1	23	655	677	655	677	0.97
18	18	4.4e-07	2.5e-05	24.6	0.6	1	23	683	705	683	705	0.97

Sequence Information

Coding Sequence: ATGAACACGATTacctgcgattggtgcttgcaggAAGCGCCGGTACAGCCGACCGAGGAGAGGTTGTGGCGCTTTTGGAAAACCATCAGCAATGAGGATCCGCTAGTAGCGAGTGGCAGGAGCATGTGCGAGAAATGTAAGTCGTGTTACGAGGATTTCTCCACGTACATCGACAGGTGTAAGAGCAACGAGTCCATAATAGATAACGTAATGGTTCCGGGACATGTGAAAGAAGAACCTCTGGTCGACATCGAGTATCATCCCTTGGTTAAAGAGGAACGGTCGTTTTCTGATCGTCCCACGGTCGATAAACGCTTTAAGTGTTCGCGTTGCGGTAAGACTTTCTCCGAATCTTGCACGTTGAAGAGGCACTTTCGCATCCATTCGGGCGACAAACTGTTCAAGTGTACGTACTGCGGTAAGAGTTTCACACAGGTTTCTCACTTGAAGAGACATTCGGACATTCACACGGACGACAAGCCGTTGTCGTGTCCTCATTGCGGTAAGTGTTTCTCCAGTTCTTCCAACTTGAGGACGCACCTCTTGCGTGTCCACACGGGCGATAAACCTTTCGAGTGTCCGCACTGTACTAAGCCGTTCCGATATTCTAGCGACTTGAAAAGCCACTTGCGCACCCATACGGGCGACAGACCTTTCGAGTGTTCGGATTGCGGCAGGACCTTCTCCGACTCGACCACGTTGAAGAGGCACTTTCGTATCCACACGGGGAACAAACCTTTCGGATGCTCGACCTGCGATAAGACTTTCACTCAGTCGGCGAACTTGAAGAGACACTTGCGCCTCCACACCGGCGATAGACCTTTCAAATGTTCACAGTGCGATAAGGCTTTCGTCGAGTCCGGTACCTTGAAGACGCACGAACGTCtccacacgggcgagaagccgtTCAGGTGTTCGCTGTGCGATAAGACTTTCAACGAATCCGCCCATCTGAAGAGTCACCTGCTCATCCATACTGGTGAGAAGCCCTTCGCGTGCTCCCACTGCCATAGACGTTTCGCCAAGTCTTCCAATCTGAAGAGGCACTCACGGGATTCGAGCGACATGAACGTAAccacttgcgattggtgctcgCTGGAGGCTCCGGTGGAAGCAATCGAGGAGaggttatggcgcttctggGGAATAATCAGTAAGGAGAATCCGCCCGTCGCATCCCTCAGCAACATTTGCGTGAACTGCGTCGCCCGTTTCGAGGAATTCTCCGAGTACATCGACAGGTGCAGGAGCAACGAGTCCATAGTGGAGACGGTGCTCACCGCCGGAAGGATCAAGGAAGAACCTCTCGATTACAACCTTAAGGGAGAAACGCCAGGTGAACGTTCGACGGTTACAGAAAAACCTAATACCACTTTCGTATGTTCGTATTGCGATAAAACTTTCACTCGCTCCTCTCATTTGAAGGACCACTTGCGCATCCACACTGGCGACAAGCCGTTCGGTTGTACGCGATGCGCCAAGACGTTCGCCCAGTCGGGCAATTTAAAGAAGCACCTGCGAGTCCACGAGGGCGAGAAGCCGTTCAGGTGTTCTCACTGCGACAAGACCTTCACCACTGCCGGCGATCTGAAGGTCCACTTGCGCATCCACACCGGCGAGAAACCCTTCACGTGCCCGCTGTGCCGTAAAGCATTCACTCACTCGAGCACCATGAAGGCGCACGTGCGCGTCCACAGGGGCGACAAGCCCTACAAGTGTTCGCTGTGCGACAGGGCGTACACCTTCTACGGTTCGTTGCAGCTGCACTCGCGCACCCATACGGGCGACAAGCCGTTCACGTGCCCCTATTGCGATAAGCGGTTCCCGAGTTCTTCCAGTCTGGCTATTCACGTGCGCGTGCACACGGGCGACAGACCCTACGCGTGTGCGCAGTGCGATAAGACCTTCACCCAACAGAACTCCTTGAAGAGGCACCTGCGCGCTCACGCCGGCGACAAGCCTTTCGCGTGTTCGTATTGCGACAGACGGTTCCCCGGCCCGTCTAATTTGAGGGTTCACCTGCGCGTCCACACGGGCGACAGGCCTTTCGCGTGTGCGCAGTGCGATAGGACTTTCACGCAGCCCAACTCGTTGAAGAGGCACCTGCGCGTTCACGAAGGGGACAAGCGATAA
Protein Sequence: MNTITCDWCLQEAPVQPTEERLWRFWKTISNEDPLVASGRSMCEKCKSCYEDFSTYIDRCKSNESIIDNVMVPGHVKEEPLVDIEYHPLVKEERSFSDRPTVDKRFKCSRCGKTFSESCTLKRHFRIHSGDKLFKCTYCGKSFTQVSHLKRHSDIHTDDKPLSCPHCGKCFSSSSNLRTHLLRVHTGDKPFECPHCTKPFRYSSDLKSHLRTHTGDRPFECSDCGRTFSDSTTLKRHFRIHTGNKPFGCSTCDKTFTQSANLKRHLRLHTGDRPFKCSQCDKAFVESGTLKTHERLHTGEKPFRCSLCDKTFNESAHLKSHLLIHTGEKPFACSHCHRRFAKSSNLKRHSRDSSDMNVTTCDWCSLEAPVEAIEERLWRFWGIISKENPPVASLSNICVNCVARFEEFSEYIDRCRSNESIVETVLTAGRIKEEPLDYNLKGETPGERSTVTEKPNTTFVCSYCDKTFTRSSHLKDHLRIHTGDKPFGCTRCAKTFAQSGNLKKHLRVHEGEKPFRCSHCDKTFTTAGDLKVHLRIHTGEKPFTCPLCRKAFTHSSTMKAHVRVHRGDKPYKCSLCDRAYTFYGSLQLHSRTHTGDKPFTCPYCDKRFPSSSSLAIHVRVHTGDRPYACAQCDKTFTQQNSLKRHLRAHAGDKPFACSYCDRRFPGPSNLRVHLRVHTGDRPFACAQCDRTFTQPNSLKRHLRVHEGDKR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00392897;
90% Identity: iTF_00392897;
80% Identity: iTF_00392897;