Basic Information

Insect: Cryptocephalus moraei
Gene Symbol: PLAGL2
Assembly: GCA_946251935.1
Location: CAMIUL010000425.1:37580-39427[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 1.3e-05 0.0011 19.5 3.7 1 23 42 64 42 64 0.98

2 7 4.8e-06 0.00041 20.9 3.4 1 23 70 92 70 92 0.97

3 7 8e-06 0.00069 20.2 8.5 1 23 98 120 98 120 0.97

4 7 0.045 3.9 8.4 1.2 1 23 127 151 127 151 0.96

5 7 0.00089 0.077 13.8 0.2 2 23 159 180 158 180 0.96

6 7 2.3e-05 0.002 18.8 2.1 1 23 194 216 194 216 0.97

7 7 0.00016 0.014 16.1 4.8 1 23 222 245 222 246 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	1.3e-05	0.0011	19.5	3.7	1	23	42	64	42	64	0.98
2	7	4.8e-06	0.00041	20.9	3.4	1	23	70	92	70	92	0.97
3	7	8e-06	0.00069	20.2	8.5	1	23	98	120	98	120	0.97
4	7	0.045	3.9	8.4	1.2	1	23	127	151	127	151	0.96
5	7	0.00089	0.077	13.8	0.2	2	23	159	180	158	180	0.96
6	7	2.3e-05	0.002	18.8	2.1	1	23	194	216	194	216	0.97
7	7	0.00016	0.014	16.1	4.8	1	23	222	245	222	246	0.94

Sequence Information

Coding Sequence: ATGCATACAGACCAACCAGGCCCGTCAGGTCTCCAAACACCGAAGACAAAACCCTTGCCAGTCCAGCTCAAAGTGAAGAAAACCCGTAGGCCACCTCCCGAAGAAACATCTCTGAAGAAGTTTCACACATGCCAGTTATGCGAGAAAACATTTTCAACCATCGACAAGCTCAACAAACACCAACAGAGCCACGTGAGCACGTCACCATTCAAATGTGAACACTGCAAGAAGGTGTTCTCTTCGAAATTCAAGCTCGTCAGGCATGCTCTGATACACTCGGATAGAAAACCATTCTGTTGTACAGTCTGCGATAAGACGTTCCATCGGAAAGACCATCTCAAGAATCATATCAAGGTGCATAGCCCACAGAAAGAAGTATACACCTGCGAGAAGGAGAGCTGCCGGAAACAATACACCTCGCTGTTGAGTTACAGGAAACATTTGGCTGTCCACGCCGCCGAAGAAGGCAACCTGGAATGCCAAATATGCACAGAGAAATTCGAGACCAAGGACGACATTTTGTACCACCTGAAAATCCACGCGGGCAGTAGAACGGTGAAGAATCCCAGCGAGAAAAAGTTCACTTGCGATTATTGCGATAGGAAGTTTTTCACGAAAAAGGACGTAAGGAGGCATCTCGTGGTACATACGGGCATGAGGGATTTCCTCTGTCAGTTCTGTCCACAAAGGTTTGGAAGGAAGGATCACCTTGTTAGACATATAAAAAAATCGCATCATGCTCAGTACCGACCGCCTGAAGAGACTGTTACAACTGCCACTGTCAAGACGGAGGGACTGGAACCAATCAAAGTTGAGAGTAACATCGAAGTCAAAACGGAATATCCGGAGAGTAGTAGCGAGTACCAAGAAGAACAAACCGATCCTAGTTTACTACTGCCACCTACTTCAGAACAAGTTGAATTAAAGGACCTGGGCAGCCAAATATTTGAAGAGGAACTGTCCGAGGCTTCCCAACCAGCTATCCAGATTAGCGAAAACCTTGAAGAAGCTAGTCAAGAGCCGCTCGATGTGGTTCTAAACAATCCAGAACTCCTCCAGAAGCTGTTGCAGCCCTCGGAAGAGAAAAACCTACCATTGCCCGGCTTCAGCCAGACCTTCCAGTCACCGCCTGGGCCGCCGCCAGGGCCCTCCCAACAGTAG
Protein Sequence: MHTDQPGPSGLQTPKTKPLPVQLKVKKTRRPPPEETSLKKFHTCQLCEKTFSTIDKLNKHQQSHVSTSPFKCEHCKKVFSSKFKLVRHALIHSDRKPFCCTVCDKTFHRKDHLKNHIKVHSPQKEVYTCEKESCRKQYTSLLSYRKHLAVHAAEEGNLECQICTEKFETKDDILYHLKIHAGSRTVKNPSEKKFTCDYCDRKFFTKKDVRRHLVVHTGMRDFLCQFCPQRFGRKDHLVRHIKKSHHAQYRPPEETVTTATVKTEGLEPIKVESNIEVKTEYPESSSEYQEEQTDPSLLLPPTSEQVELKDLGSQIFEEELSEASQPAIQISENLEEASQEPLDVVLNNPELLQKLLQPSEEKNLPLPGFSQTFQSPPGPPPGPSQQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00393059;
90% Identity: iTF_00393059;
80% Identity: -