Basic Information

Insect: Crossocerus cetratus
Gene Symbol: Zfa
Assembly: GCA_963675795.1
Location: OY776663.1:9086249-9091225[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 24 0.0001 0.0089 16.5 0.4 3 23 112 133 110 133 0.90

2 24 0.0033 0.29 11.8 0.5 1 23 138 161 138 161 0.96

3 24 1.7e-05 0.0015 19.0 1.4 3 23 179 199 177 199 0.95

4 24 1.4 1.2e+02 3.5 0.8 1 23 204 227 204 227 0.87

5 24 0.069 6.1 7.6 8.0 1 23 233 256 233 256 0.96

6 24 2.4e-06 0.00022 21.6 1.0 1 23 262 284 262 284 0.98

7 24 6.5 5.8e+02 1.4 2.0 2 19 290 307 289 312 0.80

8 24 0.00053 0.047 14.3 0.5 1 23 319 341 319 341 0.97

9 24 2.1e-06 0.00018 21.8 1.7 1 23 345 367 345 367 0.99

10 24 2e-05 0.0017 18.8 0.3 1 23 373 395 373 395 0.96

11 24 1.9e-05 0.0017 18.8 0.3 1 23 401 424 401 424 0.97

12 24 0.00066 0.058 14.0 3.0 1 23 535 557 535 557 0.97

13 24 0.0027 0.24 12.1 2.1 1 23 598 621 598 621 0.98

14 24 0.0035 0.31 11.7 0.4 3 23 635 656 633 656 0.94

15 24 0.0031 0.28 11.9 3.4 2 23 665 687 664 687 0.94

16 24 2.2 2e+02 2.9 7.4 2 23 761 782 761 782 0.97

17 24 0.00014 0.013 16.1 2.8 1 23 791 814 791 814 0.98

18 24 0.061 5.4 7.8 2.4 1 23 829 852 829 852 0.96

19 24 2.4e-06 0.00022 21.6 1.3 1 23 858 881 858 881 0.96

20 24 0.023 2.1 9.1 0.8 3 23 888 909 886 909 0.94

21 24 0.00013 0.011 16.2 0.3 1 23 914 937 914 937 0.97

22 24 3.3e-08 2.9e-06 27.5 0.4 2 23 944 965 943 965 0.97

23 24 4e-07 3.5e-05 24.1 0.8 1 23 971 993 971 993 0.98

24 24 7e-07 6.1e-05 23.3 0.1 1 23 999 1021 999 1021 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	24	0.0001	0.0089	16.5	0.4	3	23	112	133	110	133	0.90
2	24	0.0033	0.29	11.8	0.5	1	23	138	161	138	161	0.96
3	24	1.7e-05	0.0015	19.0	1.4	3	23	179	199	177	199	0.95
4	24	1.4	1.2e+02	3.5	0.8	1	23	204	227	204	227	0.87
5	24	0.069	6.1	7.6	8.0	1	23	233	256	233	256	0.96
6	24	2.4e-06	0.00022	21.6	1.0	1	23	262	284	262	284	0.98
7	24	6.5	5.8e+02	1.4	2.0	2	19	290	307	289	312	0.80
8	24	0.00053	0.047	14.3	0.5	1	23	319	341	319	341	0.97
9	24	2.1e-06	0.00018	21.8	1.7	1	23	345	367	345	367	0.99
10	24	2e-05	0.0017	18.8	0.3	1	23	373	395	373	395	0.96
11	24	1.9e-05	0.0017	18.8	0.3	1	23	401	424	401	424	0.97
12	24	0.00066	0.058	14.0	3.0	1	23	535	557	535	557	0.97
13	24	0.0027	0.24	12.1	2.1	1	23	598	621	598	621	0.98
14	24	0.0035	0.31	11.7	0.4	3	23	635	656	633	656	0.94
15	24	0.0031	0.28	11.9	3.4	2	23	665	687	664	687	0.94
16	24	2.2	2e+02	2.9	7.4	2	23	761	782	761	782	0.97
17	24	0.00014	0.013	16.1	2.8	1	23	791	814	791	814	0.98
18	24	0.061	5.4	7.8	2.4	1	23	829	852	829	852	0.96
19	24	2.4e-06	0.00022	21.6	1.3	1	23	858	881	858	881	0.96
20	24	0.023	2.1	9.1	0.8	3	23	888	909	886	909	0.94
21	24	0.00013	0.011	16.2	0.3	1	23	914	937	914	937	0.97
22	24	3.3e-08	2.9e-06	27.5	0.4	2	23	944	965	943	965	0.97
23	24	4e-07	3.5e-05	24.1	0.8	1	23	971	993	971	993	0.98
24	24	7e-07	6.1e-05	23.3	0.1	1	23	999	1021	999	1021	0.98

Sequence Information

Coding Sequence: ATGAAATTGCAGCAAATCACAATGGTCTCTGTTCCTTACTATCAAGAAAGAATTTATTGGAACGCTAAGGACTTAGAGTCACGAACAACGAAGAAGTCAGCAGTCCATGGGGTGAGGAAAAGGGTGCTCGTCAGCAGCTTACGAAACACCACGGCAGTAAGGACCAAAAAACGTCGTCAGATTGACACTGAGAAAGAGAACCAATTATCAAACCTAGAAGAGAACGTCCCACAAACTGACCAGAAGAAGGTAGAGATAAAGCAGGAAGAGATACACATAAAGCACGAAATTTTGCCGGAAACTGAGACTAATACTTCGACGGCCACAATAAATTGTGAGCTGTGTGGGAAAGTTTTTTCCACGAGAAGGAGTTACATCAAGCACAAAGGGTCAGTGCACGTACCTAGTATCTACGAGTGTGATGTATGCAAACTGAAGTTTAAGCAAATGGCGGCAGTGAGGAAGCATAAGATTAAAGTACACCGCGAAGTGCCTTTGCAGAATGAAATGAAACCACTGACTAATATAGTAAATTGTGATCAGTGTGGTAAAACTTTTACCACTAGAAGAAGTTATCAGAAGCACAAGGCAGTGCATGCACCGAAAATCTACGAGTGCGATATATGCATGCAAAAATTCAAGAAGAAGTACATCGTCGCCAAACATAAAAAGGCTGTGCATGGAGAATCCGATCCATACATCTGCCACTACTGCGACTTCAAGACCCACCACAGATCTTATTTAAATATCCACATCACGCGCAAACACACGGATACTTTCCAGTTTCCCTGCGAGAAGTGCGATCGAAAATTCCGCGTAAAGGCAGACTACCAAAAGCACATGATCACCCACGATGGTGTTCCCTGCATCTGCGATATCTGCGGCGTCAGCCTACCCAACAAAATGTCCCTGTACTTCCATAAGCACTACAATCATCGCACCAAAGAAAACAGTTTTCCCTGTCCACTTTGTAAGAGGAAATTGCAATCTCAGAAGAATCTTGAACTCCACATGGAACAACACGAACGCCGATATGTCTGCGACGAGTGTGGATTGACGCTAACGCGCAAATGTGCTCTCAAGAAACATATAAGAACACACTCCGGCGAAAAGCCACATGCATGTGATGTTTGCGGAAGGTCATTTGCCAGCGCTAGTGGAAGAAAAGTTCACATGTTAACTCATTCGGGTATCAGGCCGTACATTTGTACGGTTTGCGGATACAGTTTCACGCAGCGTCCAGCTCTCTCCGTTCACTGGAAGAAGAAACACGCGGACGTGTCCGTGCCACCGCCAGCAGCGGTCCCGATAAAGAGTATAATCGATAGCATGACAAGGGGAAAACGCAACAATCTGTCGTGCGCCAACACTTCCGCCGACGTCGCAGGAAACAGTACCGCATTATCGACAATTAGACGTGAAGTATTATCGTCCCCAGAATCTCGAAAGGCAAGCCCTCCGAAGTCAGCTGAAAATCTCGTAACATTTGTTCCCATTTCATCTATCAAAACCGAGGAGGGTGAAGAGCAGACTGCTGTGCAGAAGACTGGAACCACTTTGGTTGATAGTTTTACGCACTTGAACAAAGTGTCTTGGGACAGTTTCTCGTGCAACAAATGTAAGATGATTTTCCCCACGGAGAGTATGTTGCACCGGCACAAATTATCGCACAACGTGAATTCCTGGCTCAGGAAAGATCAGCTTCGAGACAAGTACATTCATCGCCTAAAGACCAGCTTGAAGAAGCTCAGCAGACAGTCGAAGGTCCAGCAGCAGCTGGACAAATATGAGTATGTGTGCTCACTGTGTGGATTCGGGTGCAACAGAAGAGTGACATTAACGATGCATGCGAGAAAGAAGCATAAAACGAGtgaggcgaaagtagcctccCAGAAAATTGCTTGCACAATTTGCGGTTCTAAATGCACCTCCCAAGACGCCGTGAATAAGCATATAAATGAGGAGCATACGAATCCTGTAACCAAGTATCTCCGCTGTGAAAAGTGTAACTTCGAGTGCAAAAGAAATAGTACGCTGGCCTCACATATGGTCAAGCGTCATCAAAACGAGAGCGAAAACGTGGAGCCGTCACCGAAGAAACGATCGAGATCACCGAAAACTAATATCCACCCAAAGAAAGAGATTATCGATCAGACTTCCCATCAACTTGTAAGAGACTCAGATAAGGTGGGAAACGAAAACGCGGAGGATCAAAATGAAGATGTCACAGCTGCTGCTAACAGGGTATCCAAGAAGCAAGCGAGAAAGTCTGTGGAAGAGCAGTGCAATATGTGTGACTTCAAGTGCTCGGCAAAGAGTACTATGCACTCTCATAAGCGCCAGCATAAAGCCGAGAGCATCAACGAGGTATATTCCTGTAACGAGTGCGGCTTCAAAACGTCGAAGAAGTCCTCTCTGTATTCGCACATTAAAAGGAAGCACCGGGTTGTCAAAACCAGCACTGGCGAGACGGTGCCGCAGTACTTCTATTGCAATCAGTGCGAGTACAAGAACAAGAATAAATACGAGCTAAAAGTTCACGTTCTGCGGAAGCATACAGACGACTTCAAATTCTCCTGCGAGACTTGCGGCAAGAAGTTCAAAGTCAAAGGAGATCTAACCAACCACATTCGCTTCACCCACAAGGAGCAGCCTGTAATCTGTGACGTCTGCGGGAAGACATGTCTAAACAGTAACTCCTTGTATGTTCATCAGAAGTTCGCCCATTACAAGGCCAAGTATGAATGTCCAGTTTGCAAGAGGCGCATGGTGAGCCAAGAGAATCTGAACGAACATATGCTCAGGCAACACGAGAGACGGGAGAACGTGGTCTGCGAGGAATGCGGCAAGACCTTTTCGAGGAACAGCAGGCTTAAAGTCCACATGCGAATTCACACTGGGGACAAGCCTTACACCTGCACAATTTGCAACAAATCATTCGCTCGAAGAACTGCGCTGAAGCAACACTTACTAATACATACCGGCATCAGGCCGTACGTTTGCGACATTTGCGGGAAGGCGTTCACCCAAAAGCCTGGACTCATCAGTCATAGGAAGTCCCATCCTGGCACGCATCCACCGTTACCCAGGGTTCTGATTGATCACATATTGAACGATGTTATGAACAACTGA
Protein Sequence: MKLQQITMVSVPYYQERIYWNAKDLESRTTKKSAVHGVRKRVLVSSLRNTTAVRTKKRRQIDTEKENQLSNLEENVPQTDQKKVEIKQEEIHIKHEILPETETNTSTATINCELCGKVFSTRRSYIKHKGSVHVPSIYECDVCKLKFKQMAAVRKHKIKVHREVPLQNEMKPLTNIVNCDQCGKTFTTRRSYQKHKAVHAPKIYECDICMQKFKKKYIVAKHKKAVHGESDPYICHYCDFKTHHRSYLNIHITRKHTDTFQFPCEKCDRKFRVKADYQKHMITHDGVPCICDICGVSLPNKMSLYFHKHYNHRTKENSFPCPLCKRKLQSQKNLELHMEQHERRYVCDECGLTLTRKCALKKHIRTHSGEKPHACDVCGRSFASASGRKVHMLTHSGIRPYICTVCGYSFTQRPALSVHWKKKHADVSVPPPAAVPIKSIIDSMTRGKRNNLSCANTSADVAGNSTALSTIRREVLSSPESRKASPPKSAENLVTFVPISSIKTEEGEEQTAVQKTGTTLVDSFTHLNKVSWDSFSCNKCKMIFPTESMLHRHKLSHNVNSWLRKDQLRDKYIHRLKTSLKKLSRQSKVQQQLDKYEYVCSLCGFGCNRRVTLTMHARKKHKTSEAKVASQKIACTICGSKCTSQDAVNKHINEEHTNPVTKYLRCEKCNFECKRNSTLASHMVKRHQNESENVEPSPKKRSRSPKTNIHPKKEIIDQTSHQLVRDSDKVGNENAEDQNEDVTAAANRVSKKQARKSVEEQCNMCDFKCSAKSTMHSHKRQHKAESINEVYSCNECGFKTSKKSSLYSHIKRKHRVVKTSTGETVPQYFYCNQCEYKNKNKYELKVHVLRKHTDDFKFSCETCGKKFKVKGDLTNHIRFTHKEQPVICDVCGKTCLNSNSLYVHQKFAHYKAKYECPVCKRRMVSQENLNEHMLRQHERRENVVCEECGKTFSRNSRLKVHMRIHTGDKPYTCTICNKSFARRTALKQHLLIHTGIRPYVCDICGKAFTQKPGLISHRKSHPGTHPPLPRVLIDHILNDVMNN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00633788;
90% Identity: -
80% Identity: -