Basic Information

Insect: Criorhina ranunculi
Gene Symbol: ZEB2
Assembly: GCA_951813785.1
Location: OX638381.1:84321402-84323536[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 1.1e-06 0.00011 22.7 3.3 2 23 228 249 227 250 0.95

2 11 0.0004 0.039 14.7 0.1 1 21 317 337 317 338 0.95

3 11 1.5e-07 1.5e-05 25.5 0.2 1 23 346 368 346 368 0.98

4 11 6.5e-06 0.00065 20.3 0.1 1 23 372 395 372 395 0.91

5 11 7.4e-07 7.4e-05 23.3 0.9 2 23 402 423 401 423 0.98

6 11 1.6e-06 0.00016 22.3 0.2 1 23 429 451 429 451 0.95

7 11 2.6e-06 0.00026 21.6 0.8 1 23 457 479 457 479 0.99

8 11 3.2e-06 0.00032 21.3 0.9 1 23 485 507 485 507 0.97

9 11 0.00018 0.018 15.8 1.0 1 23 513 535 513 535 0.98

10 11 0.00021 0.021 15.6 3.7 1 23 541 563 541 563 0.99

11 11 2.6e-06 0.00026 21.6 0.4 1 23 569 591 569 591 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	1.1e-06	0.00011	22.7	3.3	2	23	228	249	227	250	0.95
2	11	0.0004	0.039	14.7	0.1	1	21	317	337	317	338	0.95
3	11	1.5e-07	1.5e-05	25.5	0.2	1	23	346	368	346	368	0.98
4	11	6.5e-06	0.00065	20.3	0.1	1	23	372	395	372	395	0.91
5	11	7.4e-07	7.4e-05	23.3	0.9	2	23	402	423	401	423	0.98
6	11	1.6e-06	0.00016	22.3	0.2	1	23	429	451	429	451	0.95
7	11	2.6e-06	0.00026	21.6	0.8	1	23	457	479	457	479	0.99
8	11	3.2e-06	0.00032	21.3	0.9	1	23	485	507	485	507	0.97
9	11	0.00018	0.018	15.8	1.0	1	23	513	535	513	535	0.98
10	11	0.00021	0.021	15.6	3.7	1	23	541	563	541	563	0.99
11	11	2.6e-06	0.00026	21.6	0.4	1	23	569	591	569	591	0.99

Sequence Information

Coding Sequence: ATGTCACTTGAAATCACTAAAATCTGTAGAACTTGCCTAGCGCTGGAGGGGGCACTCCTATCCATCTATGACAGCAAAGGAACTTCAGGTGGAAATGGATGTATCGCCGATATGCTAGGAGATCTCACAAACATCCCACCGAAACAATTCGATGGAATGCCTGAAAAAGTATGCCTTGTGTGCGTTAGTGAAATAAGTCGCTGCTACTCGTTCAAAATGAAGTGCGAAAACTCTGATAGGACACTTAGACAACTTCTTAATATTACAGAAGAGTCAGAGGAACCACAAGAGGAGGTGAAGTTGAAAACAGAAGCTAGTGCTTCGGCCAAGCTGGTCGATGAAAAGAAGAGGCCACAGAAGCGAAAAGCGGAAACTAGCATAAGAATACTCCACCAAGAGACCGATCAAGGGATATCTGGTGAATCGACTGAAGTGTATTCGTTGGAGACACAAGAGGCAATAGAAGCTTCCTACTTTGTCATCGGTTCAGACGAGGAGGAGAATGAAGATGATGAGGAAAATAATGAAACGCACGATGGGAAAAATTCGGGTGACTATGATGATGTACTCGTAAATCAACCACAGGAAAACCAAGAGAATGAAGTTGATGACGAGGCGAATGACTCTGATGAATACAAACCTGTAAAACGACGATCGACTGTACGGAAAAAGGAAGAACTCAAGTGTCCACTGTGCCCCATGACATTTGTCCATGCAAGGAATCTTAAAAAACACATCCGCAGGCATCATCATTTGCCagaaacaacgtacgatcaaGCTGAACAGCCACAAGCTTCCAGTAAAGATAATGAAGTGGAAGGAGAACTGCAGGCAGAGCAACATGGAGACTTTGAGGTGGAAGTGCAGTCGATCGGAGAAGCCGATGAGACTATTGTCATCGAAGACAATCAACTACTAAAGGAACTCGTTGAAGTTCAGATGCACAAACATCGTTGTCCACGCTGTGGAGCTGGCTTTGCTCAGGAAAAGTCACTTAATATCCATATTAAGCAAAACAAGTGCACCGAGAAGCAGTATGCTTGCGGAAAGTGTCAGAAGGTATTCATTTCGCCTGAAAATCTTCGCGATCACATACGAACTCACAGAGATGAGTTCGTCTGCAGCGACTGTGGTGAAGCATTCAGCCAAAAGGAAGACCTCAACGAGCACAAAGCGGAAAAACATAGCCTCAAGGTGAGGAATCAGTGTCCGAACTGCAAGAAAGtttttacgATGCTGTCGACTCTCAAGGACCACATGCGTATCCACAGCGGTGAAAGACCTTTTCTTTGTGCAGTGTGCGGCAAGGGTTTCAGTCAGAACGCCAACCTCAAGCAGCATGTGATGCGACATAACAAAACAAAGCCGTTCAAGTGCGAAGAGTGCTCGCGCTCATTTGTCAGCAAAGGAGAACTCTACTCTCATGTCCGAAGTCACACCGGCGATCATCCGTTCGCCTGTGACATGTGTAAGACGGCATTCACCACGTCCAGTTCTTTGGTGAAACACAAACGCATTCATACCGGTGAGCGACCGTACGCCTGTGAGTTCTGTCCGATGCGGTTTACTGCACTCAACACCCTCAAGAACCACCGACGGACGCACACCGGCGAGAAaccattcaaatgcaaattttgcCAGCGTGGATTCGCCCAGAAGAGTGACTGCGCGATACACATGCGAACACACACCGGTGAGCGGAGATACGTCTGCCAGATCTGCGGTTCAGCGTTCCAACAATCAGGCACCCTGCGGACGCATATGAAAACCCACAGAGGGAAGGATATTGCGCTACAGCCGAAGGAGGAGACAGAAGAAGCAGAGGAAGCTGAACAATCACCAAGTGTAATCGATTTGGGCGGTGATGACGAGATGAACGAAGAACAACAGGAAGAACACATGGAAGATCAAAAAAAGAAAGCCACGCCATTGGAAGTAGCAGTCGACATGGGCGACGATGACCTCTTGCACTTTGCCATCGAAGAGTGTTCCAGCGAAAACAACGATTTTAGTGGTGAATGA
Protein Sequence: MSLEITKICRTCLALEGALLSIYDSKGTSGGNGCIADMLGDLTNIPPKQFDGMPEKVCLVCVSEISRCYSFKMKCENSDRTLRQLLNITEESEEPQEEVKLKTEASASAKLVDEKKRPQKRKAETSIRILHQETDQGISGESTEVYSLETQEAIEASYFVIGSDEEENEDDEENNETHDGKNSGDYDDVLVNQPQENQENEVDDEANDSDEYKPVKRRSTVRKKEELKCPLCPMTFVHARNLKKHIRRHHHLPETTYDQAEQPQASSKDNEVEGELQAEQHGDFEVEVQSIGEADETIVIEDNQLLKELVEVQMHKHRCPRCGAGFAQEKSLNIHIKQNKCTEKQYACGKCQKVFISPENLRDHIRTHRDEFVCSDCGEAFSQKEDLNEHKAEKHSLKVRNQCPNCKKVFTMLSTLKDHMRIHSGERPFLCAVCGKGFSQNANLKQHVMRHNKTKPFKCEECSRSFVSKGELYSHVRSHTGDHPFACDMCKTAFTTSSSLVKHKRIHTGERPYACEFCPMRFTALNTLKNHRRTHTGEKPFKCKFCQRGFAQKSDCAIHMRTHTGERRYVCQICGSAFQQSGTLRTHMKTHRGKDIALQPKEETEEAEEAEQSPSVIDLGGDDEMNEEQQEEHMEDQKKKATPLEVAVDMGDDDLLHFAIEECSSENNDFSGE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -