Basic Information

Gene Symbol
salm
Assembly
GCA_958507055.1
Location
OY293827.1:23958898-23970185[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 6.7e-06 0.001 20.9 0.9 1 23 407 429 407 429 0.98
2 9 9.1e-06 0.0014 20.5 1.9 1 23 435 457 435 457 0.98
3 9 0.083 13 8.0 3.8 2 23 775 796 774 796 0.98
4 9 5.7e-08 8.8e-06 27.4 0.6 1 23 802 824 802 824 0.97
5 9 8e-05 0.012 17.5 2.6 1 23 834 856 834 856 0.98
6 9 0.1 16 7.7 4.5 2 23 1127 1148 1126 1148 0.97
7 9 0.06 9.2 8.5 1.0 1 14 1154 1167 1154 1168 0.93
8 9 1.8e-06 0.00028 22.7 4.0 3 23 1335 1355 1333 1355 0.96
9 9 2.6e-07 4.1e-05 25.3 0.9 1 23 1361 1383 1361 1383 0.98

Sequence Information

Coding Sequence
ATGTACAGTAGTGAGCAGACGTGTCTGCTGCTCCGGTTATATTCACAGTTGGCGGTGAATAGTGCCGCACAAAAAGTATTTAGGGACTGCATCGAGGCTAGAAGGAAACTCATCGAGGGCGCTGCTGCTATAGACGAAGATAACAACAGCGATGATAATGATGATTATGAGGGTAGCGGCAAAAACGATGGTGGTGGTGTTCCGCAAGATGGCGCCACAATCCCAACACTTCCAGAAGTGTTGATGTGTCAAAGGTGCCAGGAACAGTTTACAGAAGTGCAAGAATATCTAACACACAAGGCTGAATGCGATAAAAAGGCAATCAAGCACGATGATCCCGCACATTCGGATCCCGAAGACATGGTTGTATCGGAagaggaagaagaagatgaagatGACGTGAACGGAAAACGGATGGAACGCATGCGTCGACATCGACAAGATGCTGCGAATAATAACAGTGTCGAAGAAAGCTCCTCAGATGAAAATACACAAAGGCTAGGTTTTCCATTTCCAGTGCCTGCAGCACCCGGACATGTTACTCTTGAAGCGTTGCAGAATACCAAAGTGGCCGTGGCCCAATTTGCTGCCACAGCCATGGCGAACAATACGGATAATGAAACTGCGCTGCAAGAGCTCGCTGTACTACAATCCACATTGTTCACATTGCAACACCAACAAGTGCTTCAGCTGCAACTTATCAATCAGCTCCAGCACCAGCTTCAAATCGATAGGACAAAGGAGGATGAGGAGGAAGCCACCTCACCAGTATCTCCACCACCATCAGAGCACGAAGCCGAAAATATCCCTACACCAGAATCTCCTCCAATGCCACAGCCGACAGTTCCAGAGCCTCAGGAGGTCAATCAGCCAACACCAAAGCCACCGGTTGTTCAACCCATCCCAACCCAACAACAAACACCGATGATGATGCATGCGCCGGAAACCAGCATACTCAAATCGCTACCACCGCAAATCCAACCTCCAATGTGTTCCATATCATCTTCCCTAGCTTCAACTATCATAACACACACTGATGAACATCCCACCGAAGAACCAAATACCTTGGAGATGCTACAGAAGCGTGCCCAAGAAGTATTGGATAATGCCAGTCAAGGGTTATTAGCTACAAACTTAGCTGACGAGCTTGCTTTTCGCAAAAGCAAAGGTTCAATGTCACCGTACGACTCGAAAGGTCGCAACGAACCGTTCTTTAAGCATCGTTGTAGGTACTGTGGTAAAGTTTTCGGTTCAGACTCTGCACTTCAAATACATATCCGTTCTCATACCGGTGAACGACCTTATAAGTGCAATGTTTGTGGTAGTAGATTTACTACGAAGGGTAATTTGAAAGTCCACTTTCAGCGACATAGTCAAAAGTTTCCCCATATCAAAATGAATCCCAATCCCGTGCCAGAGCACCTCGACAAGTATCATCCTCCTCTATTGGCCCAGCTAGGACACCAGCCATCGTTATCACCTGGAGGTCCACCTCATCCCCCTCATCTTGGATTTCCTGGTGCTCATCCGTACCCACCGACATCGTTACCTCTATTCAGGCCGCAGCTGCCTCCACCTCCACCCGAACTTATAAACACTAGACTTCCACCATCACCTCAAAGAATTCAAGAGCCGCCTCCGAGGCTCTTCCCTCCACATCCTTTGTTCCTAAAACGAGAAAGAGAAGAGCAAGAAACTCCAGCAGATTTGAGCAAGCCTTCACAAAGATCTCCATCACCAATAGTAGATAAGAATCAACGTGATATTGAAGTAGAAGAGCGACGTGAACAAAATGAGGAAGAAAGACGGGAAAGTACTCCCCAAGTAACACCAAAACAAGAACCAAATTATAACGATAATGAGAATGAGCATGATCAAGAACGATATCCATCGCCAGTACCATACGACGAATGTAGTAATAGCACAAAATACAGCAATGAAGACATGATGGACAACAGAAGTCAAAATGGTGAGCAAAATGAGAATATGCAAGATGAACCAGAGAATCTCTCACACCGATGTAACTCTATTAATATACCATTGACCATATCCACTTCCACTGGTCAGAGGTTACCTGCGAATTTCTCGTTTGGTCATAACAGTTCTCCACCTAGCAGTGCTTCATCTGGCAGCTTGGgtcattacccaattaatcccTTAAATGATATTACCAAGGATCCATCAATCTATACCAATCTTCTTCCAAGGCCTGGCAGCAATGATAACTCCTGGGAGAGTCTCATAGAAGTGACAAAAACATCTGAAACTAGCAAACTTCAGCAGCTAGTGGACAATATCGAGCACAAGTTGTCGGATCCAAATCAGTGCGTAATTTGCCATAGAGTGTTATCATGCAAGAGCGCACTCCAGATGCACTATCGCACCCATACTGGAGAGCGGCCGTTCAAATGTAAAATCTGCGGACGAGCATTTACTACCAAAGGTAACCTCAAAACCCACATGGGAGTTCACAGGGCCAAACCACCAATGCGAGTACTACATCAATGTCCCGTGTGTCACAAGAAGTTTACCAATGCCTTGGTTTTGCAACAACATATCCGCCTACATACTGGCGAACCTACTGATCTCACCCCCGAGCAAATCCAAGCAGCTGAAATAAAAGACTTTCCTTCACCAGGTGGCTTTCCCACCCTCCCTAATTCCATGCACTCATTCCTTAGCCAAGGCTTTCCCATTCCTGGTTTGTCACCCCTCGGTCATTCAGGCATGCCCTTGAATATGAAATATGACAGGGGCGATGTTAAATCAGAGCACGAGAGtatggatgatgatgatgatgacgatgaTGACATGAGCACCTTAGATAATCAAAATATGCCGCCGTTTTCTTCTTCGCCTTTGGATGCGCAGAACAACTCATTACCCATTAATACCTTGGCTCCTCAGTACCCATTGGAAAGATTAAGTGTCTCAGCTGAGGATTTATGTTCAAACAGGAATGCAATGTCAACCACACCACCTCTTCAGAACGGAATCAAATCCCCAATGCAGTCGGGTGTGACAAGCCCTGGTGATTCAGAAGTCCGATCATCTCCTAGCCAAATACCCGTCCAAATCCCACGTCCTCCATCATCACAACAGGCTAGCAGTCCAACACCATCTGACAACTCTGTTGGTGCTCTTGATCTTACTCCTCGCAATAACAGTCATCCATCCATTACCAGTCCAGGGCCAACAACGCCGGGAAGTGGTGCTCCGCCTTTGTTCCCATCATTTGGCCTGTTACCCGCTGGAGGACAATCACCGTTGATGACTTCAGCGTTATCTTCTCTGACTTCTTCTGTGCTCACCTCAACATCTTTTAGTCCGCTCAGACTCGCCGTTGGGCCAGTTGGAAATCTTGGACGTGGAAATACCACTTGCAATTTGTGTTTCAAGACTTTTGCATGTCATTCAGCATTGGAGATTCACTATAGAAGTCACACCAAAGAGCGACCGTTCAAGTGCACTGTATGCGACAGGGGATTCTCAACAAAGGATGGTTGTGCGTGCGCACAGAGGCGTATCCAGGACGAAGCGGAACCCTGGAGGGCTAAGAAACGCAAAACTGCCCTTCATCGCAAGTCGATCCCTTCGGTGTTTCCCTTACCGATGACGCCTGGATACGCCTCGACGTGGATGGCGGGCAATATGAAGCAGCACATGCTGACGCACAAGATCAGAGATATGCCGCAACACATGTTCGAGAACAAGACACCCTCCTTGAGCGGGGATGATTCTACCCCATTGCCACCTAGTCTGCCACCTAGTAGTATCCACAATGCACTACAACCACAACCTCCGCCACCGGCTATCAGTGAGTCAGAGCTGATGCAATCACAACCACCTCAGCAACAAGTGCTGCCTCATCAGCCTCAACAGTTGCAGCCTCAGCAGCAGCAAGTGAAGCAGGAAGAATTGCAACCAATCAAAAGAGAGCCCACTGAGACTGAACTACCCCTTCCTAAGCGCCCTCCAAGCTTACAGTCAAGTAAGCACTTGTGCCACGTGTGCAATAAGAACTTCTCATCCAGTTCAGCGCTTCAGATACACATGAGGACTCATACTGGCGACAAACCATTCAGATGTACTGTGTGTCAGAAAGCTTTCACCACCAAAGGCAACCTGAAGGTACATATGGGAACACATATGTGGAGCAACGGAGCATCGCGACGCGGTCGTCGCATGTCCCTAGATCTACCACCCATCCCAATGACACCCAAGGATTCCGAATTTCTGCAGCGGAGGCCAGATCTTTTCTACCCGTACCTCCCGGCTCCATTCCTTAATGGTATGCAGCAAAAGCTGAATGAGATCTCAATGGTGCAGTCGCAACAAAATGGACTGACGGGTGCTGGTAAATATAGCGGCTTATTGGGCTTCCACTATCCGCCCCCAGAGGCTGTACGATCGCAGGCCAGCTCACCTGAGCGTGGCGAGCGGCCGCCCAGTCGCGATAACGATGTGGGTGCCCGCAGCCTGTGGGACCTCCACTTTGAGCGCAAGGCTGCCGCCGACCAGCCGCCTCCTCGGGAGGACCTGCTTCCCGCCAACAGAGAAGGGCTGGCTGCCTAA
Protein Sequence
MYSSEQTCLLLRLYSQLAVNSAAQKVFRDCIEARRKLIEGAAAIDEDNNSDDNDDYEGSGKNDGGGVPQDGATIPTLPEVLMCQRCQEQFTEVQEYLTHKAECDKKAIKHDDPAHSDPEDMVVSEEEEEDEDDVNGKRMERMRRHRQDAANNNSVEESSSDENTQRLGFPFPVPAAPGHVTLEALQNTKVAVAQFAATAMANNTDNETALQELAVLQSTLFTLQHQQVLQLQLINQLQHQLQIDRTKEDEEEATSPVSPPPSEHEAENIPTPESPPMPQPTVPEPQEVNQPTPKPPVVQPIPTQQQTPMMMHAPETSILKSLPPQIQPPMCSISSSLASTIITHTDEHPTEEPNTLEMLQKRAQEVLDNASQGLLATNLADELAFRKSKGSMSPYDSKGRNEPFFKHRCRYCGKVFGSDSALQIHIRSHTGERPYKCNVCGSRFTTKGNLKVHFQRHSQKFPHIKMNPNPVPEHLDKYHPPLLAQLGHQPSLSPGGPPHPPHLGFPGAHPYPPTSLPLFRPQLPPPPPELINTRLPPSPQRIQEPPPRLFPPHPLFLKREREEQETPADLSKPSQRSPSPIVDKNQRDIEVEERREQNEEERRESTPQVTPKQEPNYNDNENEHDQERYPSPVPYDECSNSTKYSNEDMMDNRSQNGEQNENMQDEPENLSHRCNSINIPLTISTSTGQRLPANFSFGHNSSPPSSASSGSLGHYPINPLNDITKDPSIYTNLLPRPGSNDNSWESLIEVTKTSETSKLQQLVDNIEHKLSDPNQCVICHRVLSCKSALQMHYRTHTGERPFKCKICGRAFTTKGNLKTHMGVHRAKPPMRVLHQCPVCHKKFTNALVLQQHIRLHTGEPTDLTPEQIQAAEIKDFPSPGGFPTLPNSMHSFLSQGFPIPGLSPLGHSGMPLNMKYDRGDVKSEHESMDDDDDDDDDMSTLDNQNMPPFSSSPLDAQNNSLPINTLAPQYPLERLSVSAEDLCSNRNAMSTTPPLQNGIKSPMQSGVTSPGDSEVRSSPSQIPVQIPRPPSSQQASSPTPSDNSVGALDLTPRNNSHPSITSPGPTTPGSGAPPLFPSFGLLPAGGQSPLMTSALSSLTSSVLTSTSFSPLRLAVGPVGNLGRGNTTCNLCFKTFACHSALEIHYRSHTKERPFKCTVCDRGFSTKDGCACAQRRIQDEAEPWRAKKRKTALHRKSIPSVFPLPMTPGYASTWMAGNMKQHMLTHKIRDMPQHMFENKTPSLSGDDSTPLPPSLPPSSIHNALQPQPPPPAISESELMQSQPPQQQVLPHQPQQLQPQQQQVKQEELQPIKREPTETELPLPKRPPSLQSSKHLCHVCNKNFSSSSALQIHMRTHTGDKPFRCTVCQKAFTTKGNLKVHMGTHMWSNGASRRGRRMSLDLPPIPMTPKDSEFLQRRPDLFYPYLPAPFLNGMQQKLNEISMVQSQQNGLTGAGKYSGLLGFHYPPPEAVRSQASSPERGERPPSRDNDVGARSLWDLHFERKAAADQPPPREDLLPANREGLAA

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01227602;
90% Identity
-
80% Identity
-