Basic Information

Gene Symbol
-
Assembly
GCA_958507055.1
Location
OY293828.1:86695580-86696794[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 2.3e-07 3.6e-05 25.5 1.1 1 23 113 135 113 135 0.98
2 10 2.3e-06 0.00035 22.4 1.5 1 23 141 163 141 163 0.98
3 10 4.6e-06 0.00071 21.4 5.8 1 23 168 190 168 190 0.99
4 10 0.0022 0.34 13.0 3.1 2 23 197 218 197 219 0.95
5 10 0.00035 0.055 15.5 0.1 2 23 225 246 224 246 0.96
6 10 2.3e-05 0.0035 19.2 1.9 1 23 256 278 256 278 0.97
7 10 5.9e-05 0.009 17.9 0.2 1 23 284 306 284 306 0.98
8 10 1.6e-06 0.00024 22.9 0.1 1 23 312 334 312 334 0.97
9 10 1.7e-07 2.6e-05 25.9 2.4 1 23 340 362 340 362 0.98
10 10 8.3e-05 0.013 17.4 2.6 5 23 371 389 368 389 0.94

Sequence Information

Coding Sequence
ATGACATGCAAATATTTCATGGACATTGTTGCCCCTCAAAAAACCTGCGACGACACGGAAAATCTCATGCAAACCACCGTCGATGATGCTgaacttttgaatttgttcaCATCTGAAGGTGATTGCTCATCAATTCTACAAAATATCGCTACCAATGAACAATTCCAAAGATTAATACACACCACTGAGACAACAGCTGATGCATTCGATCAAAGCTACGATGTGAGACAATTTAATAGTGACAACCTTATCGAACCACCACCATTTCAGTCACATGTACAACAACAGCAACAATACCAACAAGAGGAACAACAACTTGCCACTGAAACAAATCGCTTCGAATGCGACCATTGCGGCAAAGCATTCGCTCGCAGGAAATTGCTGATGAAACATTTACTAATCCATACACAGGCACCCAGGTATCCGTGTAAAACTTGCGGCAAACTATTCAAGCAGCGATATCAACTCACAGCGCACGAAAAGTCACACAACAAACCGACCTTTCAATGTGACATTTGCTCAAAAATGTTTATACACCGCTCACATTTGAATGTGCATCGCAAAAAACACTTGGGTGAATTCGCAGCCTACTGCCAAGATTGCCAGATGAGCTTCATATCCATGACGGCATTCAGAACGCATCGCAACACCCATCATGACAACATGAAGCTGATTTGCGAGGTGTGCGGCATCACTTTGAGCACCCTATCTGGTCTCAAGGAGCACAAACTCACCCATGCATCCAGCTATGGCAGAGAGCGCAGCCACATTTGCGAAATGTGCGGCAAAAGTTATTTGACATCGAGAAATCTGCGCAGCCACATGAAAATCCACTCGAGAATCAAGACGTACGTGTGCAGCATTTGCGGCAAATCGGTGAGCAGCCGCAACATACTCGAGACGCACATCAAGATGCACACTGGCGTCAAGGATTTCGCGTGTGATGTATGCGGCAAGGGATTTGCCTCGAAAGAGTACCTTGGCGTGCACCAGAGGACTCACAGCGGTGATAGACCGTTCGAGTGTACATTTTGTGGTAAACGTTTCACGCAGAAGACCTCGCTCACCGTCCACATTCGTTATCATACGGGCCAGAGACCGTACAAGTGCGAGTGCGGTAAAGAATTTACCACCAAAAGTCATTTGATGACACATTATAAAGCGCATGATATAGGTGGCGTTGATATTGAATATATATCGCATCCTTTGATgtag
Protein Sequence
MTCKYFMDIVAPQKTCDDTENLMQTTVDDAELLNLFTSEGDCSSILQNIATNEQFQRLIHTTETTADAFDQSYDVRQFNSDNLIEPPPFQSHVQQQQQYQQEEQQLATETNRFECDHCGKAFARRKLLMKHLLIHTQAPRYPCKTCGKLFKQRYQLTAHEKSHNKPTFQCDICSKMFIHRSHLNVHRKKHLGEFAAYCQDCQMSFISMTAFRTHRNTHHDNMKLICEVCGITLSTLSGLKEHKLTHASSYGRERSHICEMCGKSYLTSRNLRSHMKIHSRIKTYVCSICGKSVSSRNILETHIKMHTGVKDFACDVCGKGFASKEYLGVHQRTHSGDRPFECTFCGKRFTQKTSLTVHIRYHTGQRPYKCECGKEFTTKSHLMTHYKAHDIGGVDIEYISHPLM

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-