Basic Information

Insect: Crepidodera aurea
Gene Symbol: klhl21
Assembly: GCA_949320105.2
Location: OX439472.1:107819878-107830813[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.3 38 6.1 0.0 2 23 370 392 369 392 0.92

2 8 0.1 13 7.6 4.9 1 23 398 420 398 420 0.99

3 8 0.065 8.1 8.2 0.5 1 23 426 448 426 448 0.96

4 8 0.0016 0.2 13.3 1.6 1 23 458 480 458 480 0.98

5 8 0.15 19 7.1 3.3 2 23 487 508 486 508 0.96

6 8 0.076 9.6 8.0 4.9 1 23 513 537 513 537 0.96

7 8 4.7e-05 0.0059 18.1 1.7 1 23 543 565 543 565 0.98

8 8 0.0024 0.31 12.7 6.5 1 23 571 593 571 594 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.3	38	6.1	0.0	2	23	370	392	369	392	0.92
2	8	0.1	13	7.6	4.9	1	23	398	420	398	420	0.99
3	8	0.065	8.1	8.2	0.5	1	23	426	448	426	448	0.96
4	8	0.0016	0.2	13.3	1.6	1	23	458	480	458	480	0.98
5	8	0.15	19	7.1	3.3	2	23	487	508	486	508	0.96
6	8	0.076	9.6	8.0	4.9	1	23	513	537	513	537	0.96
7	8	4.7e-05	0.0059	18.1	1.7	1	23	543	565	543	565	0.98
8	8	0.0024	0.31	12.7	6.5	1	23	571	593	571	594	0.96

Sequence Information

Coding Sequence: ATGGCAGATAATCCTTCAACAACTTTCCAAAATTCCGAGTTCTCATCTATTTTGTTTCAGAAATTGTTTGAACAAAAGCAAGCCAGTAAATTTTGTGATATTACTTTATTCGtcaacaataaaataataaaagctCACAGGAATGTCCTGGCATGTAATTCTCCATATTTTGATGCTGTATTAAAAAACCACAAAATTATTAGGGAACACATTACAATATCATGTCCAGATAATAATTCTTTTAATGCAATTCTTAATTTTATGTATACAGGTGAAATAACAGTAGATCACACTATTGTTGAGGAACTTTTAAAACTAGCTAATCAGTTTCTATTAACTAAAGTTATAGATTACTGTATTGAATTTTTGGGAACAAAACTTAATGTTGTTAATTGCTTATTTACTTACTTTCTTACAAAGGAGTTTAAGTTGAAAACGCTTTGTGATATTGTTGAGAATTGGATAGCCAATCATATTGAAGATGTATGTAAAGCAGAAGAAATACTCGAGCTTAGTCCTCAACAAAttatggatttttttaaaaacaagaatttcattttgaacacaAATTTAGCTTTAAATTTATTGTCGCATTGGGTACTAATAGATATGGAAAAGcgggaaaaatattttgatcaacTTATTAAATGTTTCCCGACCAACGATATGGAACCCGTAGAAGTTTTTCATCATTTAGACACAAGCACTTTGTATAATAAAAGTGAATTATGTTTGTACAGAATTTTGGATTACCTCATAACAAATAATTGGATGCTTTCAAACTTCAAAACTAGATATGATGTTTTGCAAGTTAAATATGGACagATTTTGCATGAAAAATGTATGATAGAAGCGAAACAAACAAAAAGTACAGACACAGAGAGGATTAATTCAAAATCTTTTGAGAGAAAAGGACCATTTCTGGTAAAAGCAAAATTAAAACAGAAGCAACAAATCcttttaaagaaattaatacTATTGGGTTTAAAACCAGATATTAGAATGTCTGCTTTAAAAATgctaaatttaaagaaaagatCTCTTTCTTTGTCGGACGAGAAGGAAGATAGTGAAGgtgCACAAGAATTAGATGAAAAAATTGGTATCAAATGCCCAATATGTCTGACTACAATAAATGATAGTTTGCTACTAGAACAACACCTAGCCTTAAGTCACGCTAAGAATGTAACTTACAAATGTGGATTATGTTCTTTCGTTTGCCAGTATCATGGTGATTATTTAAATCACATGAAAACACATTTTTCTGGACCACCTTTTAAATGCGACTTTTGTGAATTTAGTGTGGAGCAAATATCAAAACTGATTTCGCATCGGGCGCAGCATTTCGACGAAAACATCTACCAATACGTGTTCAAGTGCGAGCATTGTGCCAAAACCTTTCAATTCGGACAGAACCTTGAGGCGCATCTACTTAATCACACTTCCGAGAAGAACCTTTCGTGCGATACGTGCGGTTTTCACACCAAGTTTATTAGCCACATGATTGCGCATAAAAGAATTCATGCGGCTGAACTTCATCGATGTTCTTACCCCCATTGCAAATATACGACATCCAAGAAAGCACAACTTTTAAGTCACGCAAAGAGCCACAATGGCGCGCGGCCACATACTTGCGGTGTTTGCGGAAGAGGTTTCATGGAGAAATCTCATTTGGTACGTCACGAACGAATCCATTTGGAGGAGAAACCGTTCAAGTGTTCGCATTGCGATTACGCCAGTTCGAGAAGAGACAAGCTTAAGGAACACTATACGAGACATCATGGAGAAAATGCTTCCGCTAAAGTGCCGTACAAAGCGAGACCGTTAAGAACAAACGGAAGCATGACCAAATCTAGAGCTCAGACTAATCAAGATATTTCATCAACAACATCGAACACTAATAACAGTTTTACTCACACAAACAGCACTTCTGTAGCACCTTCAAACCACGAAGTGAGTTCGGATATTCAAGAATTAATTATGCAACACCAAAGTCATTCTACAActgCTACTAATCTGACAGTATTGAATTCGACCTATCACCATTTTGGCGCAACCGACGCTCCCGATTTTCATCAAAATCATCCCGCGCACACTCAGCTAGGAACTCCGAATAATATAAGTCATCGATCTGGTTCCACTGGAACTAATTCACAACAGGCCAATAGCGCCATCGTGAATCATCATATGCTGACAACGGCCGCGAGGTCGAATACGTCCACGGCTTCTTCTACGGCTGCCGCAGTGGCCGCTGCTATGATGTTGGATCCCAGATTTCATCATAATTCTGCAGTATCATATCCTCCGAATACACCTGTATCTATGGCAATGGCCGTTGTCCAATCGTCACAGATTCAATCATCAAATCAACAATCTTTACAAAATTGTATGCCGTtattttag
Protein Sequence: MADNPSTTFQNSEFSSILFQKLFEQKQASKFCDITLFVNNKIIKAHRNVLACNSPYFDAVLKNHKIIREHITISCPDNNSFNAILNFMYTGEITVDHTIVEELLKLANQFLLTKVIDYCIEFLGTKLNVVNCLFTYFLTKEFKLKTLCDIVENWIANHIEDVCKAEEILELSPQQIMDFFKNKNFILNTNLALNLLSHWVLIDMEKREKYFDQLIKCFPTNDMEPVEVFHHLDTSTLYNKSELCLYRILDYLITNNWMLSNFKTRYDVLQVKYGQILHEKCMIEAKQTKSTDTERINSKSFERKGPFLVKAKLKQKQQILLKKLILLGLKPDIRMSALKMLNLKKRSLSLSDEKEDSEGAQELDEKIGIKCPICLTTINDSLLLEQHLALSHAKNVTYKCGLCSFVCQYHGDYLNHMKTHFSGPPFKCDFCEFSVEQISKLISHRAQHFDENIYQYVFKCEHCAKTFQFGQNLEAHLLNHTSEKNLSCDTCGFHTKFISHMIAHKRIHAAELHRCSYPHCKYTTSKKAQLLSHAKSHNGARPHTCGVCGRGFMEKSHLVRHERIHLEEKPFKCSHCDYASSRRDKLKEHYTRHHGENASAKVPYKARPLRTNGSMTKSRAQTNQDISSTTSNTNNSFTHTNSTSVAPSNHEVSSDIQELIMQHQSHSTTATNLTVLNSTYHHFGATDAPDFHQNHPAHTQLGTPNNISHRSGSTGTNSQQANSAIVNHHMLTTAARSNTSTASSTAAAVAAAMMLDPRFHHNSAVSYPPNTPVSMAMAVVQSSQIQSSNQQSLQNCMPLF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01047550;
90% Identity: iTF_00387390;
80% Identity: iTF_00387390;