Basic Information

Gene Symbol
-
Assembly
GCA_905163465.1
Location
LR990983.1:2526216-2531620[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 19 0.14 13 7.1 1.9 1 23 109 132 109 132 0.94
2 19 0.26 25 6.3 0.7 2 23 159 181 158 181 0.92
3 19 0.0015 0.14 13.4 0.4 2 23 204 225 203 225 0.96
4 19 0.064 6 8.2 0.6 1 23 229 251 229 251 0.95
5 19 0.24 23 6.4 1.6 1 23 256 279 256 279 0.94
6 19 0.0035 0.33 12.2 0.2 1 23 286 309 286 309 0.96
7 19 0.00059 0.055 14.6 0.9 2 23 317 339 316 339 0.96
8 19 3.5e-05 0.0033 18.5 0.5 1 23 345 367 345 367 0.98
9 19 0.4 38 5.7 0.1 1 13 373 385 373 387 0.93
10 19 0.0044 0.41 11.9 0.4 3 23 456 477 454 477 0.91
11 19 0.023 2.2 9.6 0.1 2 23 503 525 502 525 0.95
12 19 0.00048 0.045 14.9 0.7 2 23 548 569 547 569 0.97
13 19 4.7 4.4e+02 2.4 0.5 1 12 573 584 573 595 0.83
14 19 5.3e-05 0.005 17.9 2.4 1 23 600 623 600 623 0.97
15 19 0.26 25 6.3 0.9 2 23 631 653 630 653 0.94
16 19 0.00016 0.015 16.4 2.2 2 23 661 683 660 683 0.96
17 19 2e-05 0.0019 19.3 3.3 1 23 689 711 689 711 0.98
18 19 0.00015 0.014 16.5 0.7 1 23 717 739 717 739 0.98
19 19 8.3e-05 0.0078 17.3 4.4 1 23 745 768 745 768 0.97

Sequence Information

Coding Sequence
ATGCTTTTCTTTATAGGTGACCTTCGAGCGGTTACAGTCAAATGTAAAAATGAAGAAAACCAACCAGGTGACGCTGCATTCGTAAAAATCGTTCCAATGACATTAATCGCGCCCCTTAGCAAACCGGAGAAAATAATAAATCCGGTAACTAAACTGTCTCGGCTGGACCTAAAAGTTACGAGAGTTAAAACAATAGTTAACAACAAAAAAAAACAAGCAAAATTTGTATCTAAATCTAGCGAAATTAACAAACACAAATATAATATTCAAGAAATAATGCTTTGGTCCAATGCTACTCCAATAAAACGATGCAGGGATACTGGGTACATGTGCTGTTTTTGCAACGATCATTACCCAGACCCTGCAGATCTTAAAAAACACACATTAGAAGTCCATAAAGATACTAAACAAGCATCCTTTATGAAAAAAATGAGTATGTATGAGTATATGGTAAAGGTAGACATAACTGGACTTCATTGCAATATATGTAAAAGAAATATAGAGACAATAGAAGAATTAATGCATCATTTGGTAATTGAGCACAATAAAACGGTTTATACTGACATCAAAAACCATGTCATTCCATTCAAATTCACCACAGACGTGCTTGAATGTTTCATTTGCAAGAATGTCTTCAATAAATTCAAATTGCTTATAGCACACATGAATATACATTACAGGAATTTTATTTGTGTCATCTGTGACGCCGGATTTATTAATTCTGCAGGATTTAAGTATCATTGTAATACTCACCAGACTGGTTCGTTCAATTGTGAGCTCTGTTCACAGACATTTAATACAATTGTTAAAAAGAAACTTCATGTGAGACAAAGACACACACATAAAGATGATTTGTATAAATGCGGGTATTGTGAAGAATCGTTTGCTGATTATAGAAAGAAAGAAGCTCACTTGGTCACTGCACACGATGTCCAAATGGAATCGTCTAAATGTCAAGCATGTGATAAAGTTTACAAAAACAGGAAATATTTGGCGATTCACGTAAAACGGAACCACTTGATGGAACGGAATCATAAATGCGGCGATTGTGATATGGCGTTTTTCGGCGCGGGTGAATTAAAAAAGCATATGCTCAAGCATACTGGGCTTAAAGACTACCAGTGTGCTATATGTTTGAAGTCTTATAGCAGGCGTCCCGGTCGGGGAACTAGGATTATCAAAATAGAGAAACCAACAAAACCAACAGTTGAATTGAACTTCGTCTCGAAACTAACAACGAGGGACGCAAATAAAGTTTTGAACACAGCATTAACGGAGTCCATGAAAAATAGACAAAATCTCAAAAATATATTGCTCAATTCTAACGCCAACCCGATTAGGTGCAAAGATGGCAATGGATATGGCTGTTCCTTCTGTCCCAAACAGTTTCAAGATCCCACAGCACTTAAAAAACACTTTCTAGAAGAACACAACAGTGATAAATTAATAAAATATATGTCAGCGAAAGTTTTCGAACATGTTATCAAATTGGACATCACATATCTTAACTGCGCTCTTTGTGACAAAGATATCACTCAATTAGAAGATCTAGTGGTCCATTTGAAAAAAGAACACAACAAACCAATGCATTTGGACGCCAAAAGCCAGATAGTACCATTCAGATTCGACTCGAAGGAATTAAAATGCGTAATTTGCTCCACAAACTTCGTCACCTTCAAACTATTGCAAGAACATATGAATTCCCATTTCGGGAATTATATATGTGCGATTTGTGGGGCGGGCTTCGTCACTGATAGATTACGTCTCTGTCACGAGAAAAGGCACGAGAGTGGGGAATTCAAATGCGATCAGTGCGACAAGACATTCCAGAACGCACAGAAATTGCGTGATCACAAAAAACGAATTCATTTAGGCCTAAGCAAGAGAAACAAATGCAATTTCTGCACTGAACGATTTGTAGATTATTGGAAGAAAATGGACCATATGGTAAAAGAGCACGGCATGCCTCCGGTCCTCCTGAAATGTTCTGCTTGCGAACGAACGTTTAGCAACCAACGATCACTATCACGACATACGAAAAAAGATCACCTTTTGGAACGGAGACATAAATGTAATGAATGCGATATGAGGTTCTTCGGTAAAAGCAGCTTACAGAAACATATGGCGAAGCATACGGGGTTGAGGCAGTTTCGCTGCGATGTCTGCATGAAAGCGTATGGAAGGAAGAATACCTTGAGGGAGCACATGAGGATACATGCAAATGACAGGAGATTCGCTTGCACCCATTGTGGGCAGGCATTTGTGCAGAAATGCAGTTGGAGGAGTCACATGCGTTCTAAGCACGGAGAAGAAGTCTAG
Protein Sequence
MLFFIGDLRAVTVKCKNEENQPGDAAFVKIVPMTLIAPLSKPEKIINPVTKLSRLDLKVTRVKTIVNNKKKQAKFVSKSSEINKHKYNIQEIMLWSNATPIKRCRDTGYMCCFCNDHYPDPADLKKHTLEVHKDTKQASFMKKMSMYEYMVKVDITGLHCNICKRNIETIEELMHHLVIEHNKTVYTDIKNHVIPFKFTTDVLECFICKNVFNKFKLLIAHMNIHYRNFICVICDAGFINSAGFKYHCNTHQTGSFNCELCSQTFNTIVKKKLHVRQRHTHKDDLYKCGYCEESFADYRKKEAHLVTAHDVQMESSKCQACDKVYKNRKYLAIHVKRNHLMERNHKCGDCDMAFFGAGELKKHMLKHTGLKDYQCAICLKSYSRRPGRGTRIIKIEKPTKPTVELNFVSKLTTRDANKVLNTALTESMKNRQNLKNILLNSNANPIRCKDGNGYGCSFCPKQFQDPTALKKHFLEEHNSDKLIKYMSAKVFEHVIKLDITYLNCALCDKDITQLEDLVVHLKKEHNKPMHLDAKSQIVPFRFDSKELKCVICSTNFVTFKLLQEHMNSHFGNYICAICGAGFVTDRLRLCHEKRHESGEFKCDQCDKTFQNAQKLRDHKKRIHLGLSKRNKCNFCTERFVDYWKKMDHMVKEHGMPPVLLKCSACERTFSNQRSLSRHTKKDHLLERRHKCNECDMRFFGKSSLQKHMAKHTGLRQFRCDVCMKAYGRKNTLREHMRIHANDRRFACTHCGQAFVQKCSWRSHMRSKHGEEV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-