Basic Information

Gene Symbol
-
Assembly
GCA_905163465.1
Location
LR990957.1:3277114-3284309[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 29 0.0009 0.084 14.1 1.6 1 23 202 224 202 224 0.98
2 29 0.0013 0.12 13.6 0.8 2 20 254 272 253 274 0.92
3 29 7.8e-05 0.0073 17.4 0.1 3 23 306 327 304 327 0.96
4 29 0.00065 0.061 14.5 0.6 1 23 377 400 377 400 0.97
5 29 0.058 5.4 8.4 0.4 1 23 420 442 420 442 0.95
6 29 0.00097 0.091 13.9 0.8 2 20 483 501 482 503 0.93
7 29 0.0016 0.15 13.3 4.1 2 23 546 568 546 568 0.97
8 29 0.002 0.19 13.0 0.6 1 23 618 641 618 641 0.97
9 29 0.016 1.5 10.1 0.1 1 23 694 716 694 716 0.97
10 29 0.019 1.7 9.9 8.1 1 23 727 749 727 749 0.98
11 29 0.045 4.2 8.7 2.1 2 23 761 782 760 782 0.96
12 29 0.0027 0.25 12.6 1.4 1 23 792 814 792 814 0.98
13 29 0.0063 0.59 11.4 6.7 1 23 843 865 843 865 0.96
14 29 0.012 1.1 10.5 2.0 1 23 876 898 876 898 0.97
15 29 3.5e-05 0.0033 18.5 1.0 1 23 906 928 906 928 0.98
16 29 0.00062 0.059 14.6 0.2 2 23 948 970 947 970 0.97
17 29 0.95 89 4.5 0.3 1 23 988 1010 988 1010 0.90
18 29 1 98 4.4 5.3 1 23 1017 1039 1017 1039 0.96
19 29 0.0025 0.24 12.6 1.4 2 23 1050 1072 1049 1072 0.95
20 29 0.0026 0.25 12.6 0.1 2 23 1095 1116 1094 1116 0.95
21 29 0.00067 0.063 14.4 0.2 2 23 1197 1218 1196 1218 0.95
22 29 4.1 3.8e+02 2.5 2.1 5 23 1228 1246 1225 1246 0.92
23 29 0.027 2.5 9.4 0.7 2 23 1257 1279 1256 1279 0.94
24 29 0.095 8.9 7.7 2.4 2 23 1296 1314 1296 1314 0.90
25 29 1.3 1.3e+02 4.1 2.2 2 21 1318 1337 1317 1338 0.94
26 29 1.5 1.4e+02 3.9 1.5 2 23 1359 1380 1359 1380 0.95
27 29 0.16 15 6.9 0.5 2 23 1387 1408 1386 1408 0.93
28 29 0.0029 0.27 12.5 0.5 2 23 1419 1441 1418 1441 0.95
29 29 1.9 1.8e+02 3.6 2.1 2 19 1479 1496 1478 1499 0.92

Sequence Information

Coding Sequence
ATGGCCCTCAAGCTTGGAAAATGCAGGCTTTGCCTCAAGCTCGGCGACTTTTACTCCATCTTCACGGTGGACAATGCCCTGCAGCTGGCGGAGATGGCTATGGAATGCGCCCGGGTGAAAATTTACGATGGAGATGGACTGCCCGATAAAGTGTGCTCAGAGTGCATACAGAAGCTCAGCAGTGCATATATTTTTAAACAGCAGTGTGAACGAGCTGACCAGGAGTTACGCCGCAACTATGTCCCACCACCAGGATTCAGTATCAGTCCGCCGCCACCCAATAGACAGAGCAGTGATTCAGCCTTTTCCAATCACACAGACAGCTCCAACCTGACCAAACCCCCATCTTCTATAGAAGAAAAAGTGACACCACCCACTCGCATCAGGAAACGTAGCATAGATAGCATTGACAACGCATCCGTTGGTGGTGCATCTAGTGACTACAGACCTAGTGGCTCCAAACGCGTTGAGGAACTCAGAAGGTCCCATAAGAGGCCAAGAAAGCAATCAGAAAACACCTCCCAGTTAGATTCAGATTACGAAGACAACAACGCTTCGTTCTTGGCTGAAACCGATTCAGATGAGCCATTGCTGAAAAGTGGCTTCAGTTGTGAACTCTGTCCTAAACAATTTATATCTCACAGAAGTCTAGTTCTGCACAAAAGAGTTCATTCAGACAAAAAGGGAAACCTTGGCGAAAATGCTGTTGTTGACATACCGCAAAAGTCTGAGGATGCAGCTGATGTAGAAGACAAACTGAATTGTGACAAATGTGGAAGGACATTCAAGTTAAAGATCATGTTGAAGCGTCACCACGAAATATGCAGTAAGACATTAAGTCCAGTTAAATCACCCAAGAAAGAGTTACTTGTGTCGTTAGAACCTATTGACGGCATGAAAAGTCGAAATATTATTTGTGAAATGTGCTCAGCCAAATTCAAGACTGTGGATAATTTGGCAAAACATATGAGAGTAGTTCATGCTGCTGTTTTAAAAAAAGAAGATCAAGATAAGCGTGAGAACGGAAATGTGGCTGTCCCGTGCCTTTTTTGCCGGAAGCTTTTTGATGATTATTACGTTCATAGTGCGCATTTTGGTGTTTGTCCAAAAAAGGACGAGTCTTTGCCATATGAATGCCCTATTTGTAAAAAGGTGGCGACGAGGAAGAATTCTTATTTCTTACATCTTAAGAACATTCACTTTGAACCTCGGTTATCTCAGGGGAAGGTTTCACTCGAGCCTGACACACAGAAGTATCACGAGTGTAGGATGTGCTACAAGAAGCTCCCATCGCAAGAGTTGCTGATCACACATTTAGCGGCGCACATGTCACACATTGATGAAAACGATGGTGCAGCTGATAACGAATCTAGAGCCAGTACTATGGAAGACTCTGCATCCATCCAATCAGTGCCAAGTCAATCTGGTACCCCCACTGGCTTAGTAAAATGTCAAAAATGCGACAAAGAGTTCAAATATAGGAAAGCTCTTCAGACTCATGAGTTAAAGTGCCTAACTGAGATACCAGTGGAAGTGAAGGGTGAACCTATGGATAAACCATCCACAAGCCTACTGAGCGAGACTTCTGGCTATCGCCAGACTGAGTCAGATTCTAGTCAAGAGGAGGATGACAATACCTGCGATATTTGCGAGAAACAGTTCTCGTATCGACGGCTCCTACTTCACCATAAGAGGACAAAACACAACATGAGTTCAGGTCATAAGCGCGCCAAAATCTACCTTAAAGACTGCTCCGTTCGCTGTCTCATATGCGACATCGACATGAAAGTCGGGGCAATTAACGAACATAACCAAACACACATGTCAAAGAACATAAAGCCGAGGAACCTATACACATGTGCCGAATGCGAAGACACCTTCAAAAGCTGCTCAGCACTTGCTAATCATATAAAATTGATACATAGACTAAAACAAAAGAGGATAGAGGAAAGTGTCAATCCTTCGGATTTTTGTGAAGTCGTTGTGACGAAAGCGGAACCCCTGGACTGGATCCAGAGTCACAACGACTTTGGCGAGGTTCCGGGCGGGGAAAGCAAGCCGCTGGTAGATCTTAGCGGGTTCACCTGTCCTATATGTGCAAAGAAGATGCCAACACTCATCTCTTTGAAGAGGCATGTCAACTGGCACTCGAATGTCGGCAATAATATTGAGAAAAAATATGAGTGCTGCGTTTGCAAAGAGGCCTTCAAGTTCCAATGCCACTACAAGATCCACATGCGGGAACATTACCACGACCCGAACTTGGACCCGAAGCACCTGACGTGCACCATCTGCGGCCGCCGCAGCAAACACCTGCGCGCCGCACAGATGCATATGAAGTTCCATATGCAGACCCGCTTCCAGAACAAAGATTACCAGTGCTCCATCTGCGAGCGTGTGTTCCAGCACAGGAAAGTATACCTCTCACATATGGCTATACATTACAAAAAAGGCGATAGCGTCCAGAACACAATAGTCGGTGACGCACTCCCTACTAATGCTGATAAAAACATCTTCGACGGCACCCACACCTGCCAACACTGTGGCAAAGTCTGCGACTCTGAGAACTCCCTTAAACATCACCTGATCTGGCACACCTCCAAAACATTCCTGTATGGTGCTCGACACGAATGCAGCATTTGCAAAGTCAAGTTCACAAATAAACGGAGACTAGATCTTCACGTTAGAGCGCACTACGAAGACGATAATGGCCCCTACAAGTGTACTATTTGCGGCAAAGGCTATACTGACGAACGTTACTACCAGAAACACGTGAAGGGACATAACTTTGATCATCAGTCCCATCAAAAGAGGATAGAAAAGATTAGGAAGGATAAAGTAAAGTGTCCAATATGTTCACGATATTATCCTGACTTAGTTAAACTTATCCGTCATTTGAGGCGGACGCACCCTGAGAGTAAAATGATAAAAACCGACCCGGACGCTCCTCCACAACCGTACTATTCCTGCAAATTGTGCGCCAAAGTATTCTTAGACGAGCGACGACTACAATCTCACGAGGAAGCTCATCTTAGAAAACCAGAATTCTTTAAATGCAAGTTCTGTGGCAAGAAAACTATATCACTTAGAAACCATCATGTCCACATAAAGGGTCACCTGGCCCAAAAACACTTTGACAACCCGCTGAAGTGTCCGAACTGTGACGAGACGTTTGTTAAGGGATACGGACTTCACCATCACTTGCGCGACGTACACAACATCCACGAGACTTGGATCGCCGATCGCACAGAACAAACCCTTGACGGACCGCTAAAAGACCTGCAGTGCTCTATATGTCTGAAGGTCCTCGCCAGCAAAGGTAACTACGAGCGACATATCGACTATCACAACTCTTTGAGATGTAACTACTGCTACGATTACTTTAGCTCTCTCCGGTTCCTCGAAGGACATTTATCGTTCTCGTGCGAAAAGAAAAAGCTTCTGGGCAACACTGAAGTCTATCCCAGGAAAGTGAAATGCCATATTTGCTACAAAGCATTTCATATTCAAGTCAAACTTGATTGCCATTTGCGTACGCAACACGGGATCATAGTTAACAGGGAAATGTCGGCTGGAAAGCAAGAAATTGTCTGTGATTACTGCTTTAAGGTTTTCGAAAATGAATATGCTCTTAATAATCACAAAATTTATCACCGCACAGTTGGCTACTATGGATGCATTTACTGTAATAGGAAGTTTAATACAATGACTGTGTACAGAAAACACAAGAATTTCCATTTCTCACAACTCAATGTGGATAACCCAATGAAATGCGAACATTGTGACGAAACATTCGTCGCTTTCAGGGAAATGATATACCACATGAAAGATGTACATGGTGATGATAAAGAATGGGTGATTGAGCCCAAAGAGTCCATCGAAGAAACTTGCCCTATTTGTAACAAAAGATTTTACAATCTGCATAAGCATTTGGCCTACCACGAAGAGAATAAGTGCAAGAAATGCAGCGAATATTTCTTCTCTAGGGCAGACTTTGATAATCATTTGTGTGCCATCGAGAGCGATGACGAAGGCACTGGATACGTACCTAGCGATGATACGCCCAAATACGAGGAGTGCAGGTTCTGTTTTAAACCTATTACAAAGAAGAATTCCTTACGGTTACACAACCAAATACACAAAGGATCGGGCTCTATATCGTGTCGGTTCTGCCCACTCAAGTTTAAAACTATGGACGCGTTCAACATACACGCTTTCTCTCATCGAAGTAGAAAATATAATAAGAAACCAATAAAATGTAGAAAATGCGGTGAGAAATTTGTTAAGTACGGACCATTTATTAAGCACATGAAATTGGTTCACAAGTCTACGAAGAAGGTTCATTACAGAGCAGTGGTAAAACCTGAGAAATGTGTCGTGTGTGGAGACGACTTTCCGAATCTTCACAACCACTACCGCGCTCATCTGCTGAACCAATGCCAGCTTTGCCGCAAATATTTTACTTCATACAAAGTGTTATCTCAGCATGAATGTGACAAAGAGGATTCTGACCCTACAAAGGTGTTCACGTGCGACGCCAACTTAAACCATTTGATAAATACATATGTTCCGAAAGACGAGAAGGACGATGAGAAATTCTATGGACACACAGACGATGAGGATGATGAAGTAGACCCGCCAGAGTTCCCTGAGGAAGAGGAGAGTCAGGACAGTAAAGATATACCTATGATACAGTCGCCGATAATATCAGATGTTTTGTCGCTTTTCAAGACTGAGACAAATGGCGTGGATGAGGCGGACAATGTAGTCAATATAACTGACGATGACTCCGTGGACTGTGACCAGGTCATACCAGTTGTAGTCGTTATTGACGATGATTAA
Protein Sequence
MALKLGKCRLCLKLGDFYSIFTVDNALQLAEMAMECARVKIYDGDGLPDKVCSECIQKLSSAYIFKQQCERADQELRRNYVPPPGFSISPPPPNRQSSDSAFSNHTDSSNLTKPPSSIEEKVTPPTRIRKRSIDSIDNASVGGASSDYRPSGSKRVEELRRSHKRPRKQSENTSQLDSDYEDNNASFLAETDSDEPLLKSGFSCELCPKQFISHRSLVLHKRVHSDKKGNLGENAVVDIPQKSEDAADVEDKLNCDKCGRTFKLKIMLKRHHEICSKTLSPVKSPKKELLVSLEPIDGMKSRNIICEMCSAKFKTVDNLAKHMRVVHAAVLKKEDQDKRENGNVAVPCLFCRKLFDDYYVHSAHFGVCPKKDESLPYECPICKKVATRKNSYFLHLKNIHFEPRLSQGKVSLEPDTQKYHECRMCYKKLPSQELLITHLAAHMSHIDENDGAADNESRASTMEDSASIQSVPSQSGTPTGLVKCQKCDKEFKYRKALQTHELKCLTEIPVEVKGEPMDKPSTSLLSETSGYRQTESDSSQEEDDNTCDICEKQFSYRRLLLHHKRTKHNMSSGHKRAKIYLKDCSVRCLICDIDMKVGAINEHNQTHMSKNIKPRNLYTCAECEDTFKSCSALANHIKLIHRLKQKRIEESVNPSDFCEVVVTKAEPLDWIQSHNDFGEVPGGESKPLVDLSGFTCPICAKKMPTLISLKRHVNWHSNVGNNIEKKYECCVCKEAFKFQCHYKIHMREHYHDPNLDPKHLTCTICGRRSKHLRAAQMHMKFHMQTRFQNKDYQCSICERVFQHRKVYLSHMAIHYKKGDSVQNTIVGDALPTNADKNIFDGTHTCQHCGKVCDSENSLKHHLIWHTSKTFLYGARHECSICKVKFTNKRRLDLHVRAHYEDDNGPYKCTICGKGYTDERYYQKHVKGHNFDHQSHQKRIEKIRKDKVKCPICSRYYPDLVKLIRHLRRTHPESKMIKTDPDAPPQPYYSCKLCAKVFLDERRLQSHEEAHLRKPEFFKCKFCGKKTISLRNHHVHIKGHLAQKHFDNPLKCPNCDETFVKGYGLHHHLRDVHNIHETWIADRTEQTLDGPLKDLQCSICLKVLASKGNYERHIDYHNSLRCNYCYDYFSSLRFLEGHLSFSCEKKKLLGNTEVYPRKVKCHICYKAFHIQVKLDCHLRTQHGIIVNREMSAGKQEIVCDYCFKVFENEYALNNHKIYHRTVGYYGCIYCNRKFNTMTVYRKHKNFHFSQLNVDNPMKCEHCDETFVAFREMIYHMKDVHGDDKEWVIEPKESIEETCPICNKRFYNLHKHLAYHEENKCKKCSEYFFSRADFDNHLCAIESDDEGTGYVPSDDTPKYEECRFCFKPITKKNSLRLHNQIHKGSGSISCRFCPLKFKTMDAFNIHAFSHRSRKYNKKPIKCRKCGEKFVKYGPFIKHMKLVHKSTKKVHYRAVVKPEKCVVCGDDFPNLHNHYRAHLLNQCQLCRKYFTSYKVLSQHECDKEDSDPTKVFTCDANLNHLINTYVPKDEKDDEKFYGHTDDEDDEVDPPEFPEEEESQDSKDIPMIQSPIISDVLSLFKTETNGVDEADNVVNITDDDSVDCDQVIPVVVVIDDD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00785388;
90% Identity
-
80% Identity
-