Basic Information

Gene Symbol
-
Assembly
None
Location
scaffold:588-5729[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 19 0.00017 0.018 15.8 0.5 1 23 190 212 190 212 0.97
2 19 0.0075 0.78 10.6 3.1 1 23 218 241 218 242 0.94
3 19 0.00018 0.019 15.8 6.1 1 23 303 325 303 325 0.97
4 19 3e-05 0.0031 18.2 2.3 1 23 333 355 333 355 0.99
5 19 1.5e-06 0.00016 22.3 1.7 1 23 361 383 361 383 0.98
6 19 5.8e-06 0.0006 20.4 0.8 2 22 390 410 389 410 0.95
7 19 0.00044 0.045 14.5 5.9 1 23 421 443 421 444 0.95
8 19 4.9e-05 0.0051 17.5 1.8 3 23 452 472 450 472 0.96
9 19 0.001 0.1 13.4 1.9 1 23 478 501 478 501 0.97
10 19 0.04 4.1 8.4 2.9 1 21 507 527 507 529 0.96
11 19 2.3e-07 2.4e-05 24.9 3.1 1 23 534 556 534 556 0.98
12 19 1.1e-05 0.0011 19.6 3.9 1 23 562 584 562 584 0.97
13 19 3.6e-06 0.00037 21.1 1.3 1 23 590 612 590 612 0.99
14 19 0.04 4.1 8.4 2.6 1 23 618 640 618 640 0.97
15 19 0.004 0.42 11.5 3.4 1 23 646 668 646 668 0.95
16 19 0.00066 0.069 14.0 6.0 1 23 674 696 674 696 0.97
17 19 0.00015 0.016 16.0 5.4 1 23 702 724 702 724 0.98
18 19 0.0056 0.58 11.0 1.6 1 23 730 753 730 753 0.98
19 19 0.00019 0.019 15.7 3.1 1 23 758 780 758 780 0.98

Sequence Information

Coding Sequence
ATGAAAAACAGTAACCTACCGACAGTTAATATGAAAAAAATAATGCTAGTGAGTAACAATAATGAAATGAGAAGGCGACTCATTGTCAATAATCAAAGCTCCGTAAATACGAATTATAATTGCTACAGTTTTATGAACAAATCCGCTGATATAAAAATTACGAGCGTCCAATCATTGAGCGGAACAGAAAACTGTTGGAATGAAAATATTGACAACATAGACAATGGTCACGTACAAACAATCTGTGATGAAAATGAAACAAAATTTTCAATCAGTGAACTTACAATTAATGAAAACTCAAGTACTGAAATCGCAGATACGACTAACACTAACCGTCAAGAACTCCCATTTACATTTATAGCCGATACAAATAATACACTAGAAAATAGTTTTAATCCCTTAGATGTAATTGTAAAACAAGAAAACGATGTTGATCCTTTAGCTACAGATGTTAAGCCTGATCAACAAGAATTGAATAAAGTCTTATTGGAAAATTATAATAAAGAATCATGTATATTAGAAGGACTCCTAAAACATTATAAGCGTACTAAAATAAGTAACAAAAAGTTTGAGTGTGATATGTGTCCGAAAAAATACGTCTTGAAGCAATCTTTACAACGGCACAAAGCTGTACATGTAAAAAAACTAAAATTTCCCTGTAAAATTTGTTACTTTCAAACAAACTCGAATTCTTTATTAAAAAAACATATCACAAATAACCATCACATTACAAGACCGGTACTACGTAATGTTCGGGACTCAAAATCGAGTCAAAGCTCACAATTTAAAAAAAAGAATCATAAAACGGTTAAGATATCACAGAAAAACAATACTCGTTGCTTGAAATCAATGAAAAAATCACTGTTGAAGAAATCTATCAAAAATCGTCAATGTTTACAAAAGAGCCACACTTGTAAAGTTTGTCATAAAGTATATGCTACGAAACATACTTTAGAGCGACACAAAATTGTTCATGTAATAAAGAAAAAACAAAACTTTCAGTGTGAAGTTTGTAATCTAATATGTACTCGACAATCAAGCTTAGGAAAACATCTTAAGACCCATTTAAACAATGAAATATTCAAGTGTGATATTTGTAAGAAAATCTTTCGTCGAAAGTTAACTCTAATTCGACACATGGATTCACACGATCTGAAAATAAGAGTTGAGTGTGATAACTGCCACTTAACTTATACCAGGAAGAGCAGTTTAATTCGACATATGCGTTCTTGTTTTTGGAAGTTACCTGCCGATAGACCATTTACATGCGATATTTGTAATTCCAATTATTCGAGGAAGTCACATTTGGAATCTCACATTATACATCATCACTTGAAAGGTGAACATGTTAATTGTAAAATTTGTCTACGAAATTTTTCTCGAACGTCATCTTTAGAACATCATATGCTTATCCACATACGGGGGAAAATATACAAATGTGATATTTGTCATTCAAAGTACACTGAAGAAACTTCGTTAGCTCAACATATGCGTGATCGTCACAAAAACGAAGAATCTTTCAAATGTGACAATTGCCAGGCTGAATTTTTAACTAAACAAAATTTATCGATTCATATGAGATGTCATAAAACAGAACGATTTGAATGTACTATTTGTCAACGAAGCTTTTCTCGAAATTTCAATCTCAAACAGCACATGTATACTCACACAAACGAAAACGTATTCAAGTGTAACATTTGTCACTTAAAATTCACTCAAAAGTCAATGTTAACAACGCATCTTGAAAATCATACTCGTGATAAACAATATAAGTGTGATGTTTGTGAAGCAATTTTTCGTCAAAAATCAAAACTGAATAAACACAGACTCACTCACACGAGAGAAAAGTCATTTGAGTGCGATATTTGTCAAGCTTTCTTCTCCCATAAGTTCATTTTAGACAAACATAAACTTACTCATACAAGAGAAAAATCTTTTCACTGTGATATTTGTCCAAGCCAGTTTTGTAGTCAGTATAATCTCGATAAGCACCTAGTTCTTCATACGAGGAAAGAATTATTTGAATGCAATGTTTGCCATTCAAAGTTCATTCATAAATCTCAGTTAAAGACACACCTTTACAGTCATAGTGATAAAAAAATTTTCAAGTGCGACATTTGTGAAAGAATCTTTTCTCATCATTTTAGTTTAAAACGACACAAACTTATTCATACGGGCAACAAACAATTCAAGTGCGATGCTTGTTCAGCTAAATTTTTCACAATTCAATCTTTAACAAAGCACATTAAAAAGTCACATAAAAATAAAGAATACAAATGTGATATTTGCAAGAAACACTTTTCTGCGAAGGGTTGGCTTGACAGGCATCATCTTATTCATGCAAAGGATGAACTAGTATATAGTACAAAAAATGAACGATTAGATCATACAAGTGATTAA
Protein Sequence
MKNSNLPTVNMKKIMLVSNNNEMRRRLIVNNQSSVNTNYNCYSFMNKSADIKITSVQSLSGTENCWNENIDNIDNGHVQTICDENETKFSISELTINENSSTEIADTTNTNRQELPFTFIADTNNTLENSFNPLDVIVKQENDVDPLATDVKPDQQELNKVLLENYNKESCILEGLLKHYKRTKISNKKFECDMCPKKYVLKQSLQRHKAVHVKKLKFPCKICYFQTNSNSLLKKHITNNHHITRPVLRNVRDSKSSQSSQFKKKNHKTVKISQKNNTRCLKSMKKSLLKKSIKNRQCLQKSHTCKVCHKVYATKHTLERHKIVHVIKKKQNFQCEVCNLICTRQSSLGKHLKTHLNNEIFKCDICKKIFRRKLTLIRHMDSHDLKIRVECDNCHLTYTRKSSLIRHMRSCFWKLPADRPFTCDICNSNYSRKSHLESHIIHHHLKGEHVNCKICLRNFSRTSSLEHHMLIHIRGKIYKCDICHSKYTEETSLAQHMRDRHKNEESFKCDNCQAEFLTKQNLSIHMRCHKTERFECTICQRSFSRNFNLKQHMYTHTNENVFKCNICHLKFTQKSMLTTHLENHTRDKQYKCDVCEAIFRQKSKLNKHRLTHTREKSFECDICQAFFSHKFILDKHKLTHTREKSFHCDICPSQFCSQYNLDKHLVLHTRKELFECNVCHSKFIHKSQLKTHLYSHSDKKIFKCDICERIFSHHFSLKRHKLIHTGNKQFKCDACSAKFFTIQSLTKHIKKSHKNKEYKCDICKKHFSAKGWLDRHHLIHAKDELVYSTKNERLDHTSD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00382049;
90% Identity
iTF_00380540;
80% Identity
-