Basic Information

Insect: Cosmopolites sordidus
Gene Symbol: Zfhx4
Assembly: GCA_031761425.1
Location: JARFXV010001016.1:78214-121073[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 0.64 1.2e+02 4.9 0.1 1 23 90 113 90 113 0.90

2 15 0.029 5.6 9.1 0.5 2 23 129 151 128 151 0.93

3 15 1.1 2.2e+02 4.1 2.6 2 21 230 249 230 253 0.87

4 15 0.12 23 7.1 1.5 3 23 267 290 265 290 0.87

5 15 0.0039 0.76 11.8 1.6 1 23 308 330 308 330 0.97

6 15 0.00085 0.16 13.9 0.7 2 23 337 359 336 359 0.94

7 15 0.00047 0.09 14.7 3.0 1 23 466 490 466 490 0.92

8 15 0.0067 1.3 11.1 0.6 1 22 510 531 510 534 0.89

9 15 0.0013 0.26 13.3 0.2 1 23 581 605 581 605 0.93

10 15 0.001 0.19 13.7 0.0 2 21 669 688 668 689 0.93

11 15 0.68 1.3e+02 4.8 1.4 2 19 811 828 810 833 0.90

12 15 0.00014 0.028 16.3 2.5 1 23 1405 1427 1405 1427 0.99

13 15 0.00098 0.19 13.7 0.3 1 23 1523 1545 1523 1545 0.98

14 15 0.0078 1.5 10.9 0.4 2 23 1701 1723 1700 1723 0.96

15 15 0.45 87 5.3 3.6 3 23 1984 2006 1983 2006 0.90

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	0.64	1.2e+02	4.9	0.1	1	23	90	113	90	113	0.90
2	15	0.029	5.6	9.1	0.5	2	23	129	151	128	151	0.93
3	15	1.1	2.2e+02	4.1	2.6	2	21	230	249	230	253	0.87
4	15	0.12	23	7.1	1.5	3	23	267	290	265	290	0.87
5	15	0.0039	0.76	11.8	1.6	1	23	308	330	308	330	0.97
6	15	0.00085	0.16	13.9	0.7	2	23	337	359	336	359	0.94
7	15	0.00047	0.09	14.7	3.0	1	23	466	490	466	490	0.92
8	15	0.0067	1.3	11.1	0.6	1	22	510	531	510	534	0.89
9	15	0.0013	0.26	13.3	0.2	1	23	581	605	581	605	0.93
10	15	0.001	0.19	13.7	0.0	2	21	669	688	668	689	0.93
11	15	0.68	1.3e+02	4.8	1.4	2	19	811	828	810	833	0.90
12	15	0.00014	0.028	16.3	2.5	1	23	1405	1427	1405	1427	0.99
13	15	0.00098	0.19	13.7	0.3	1	23	1523	1545	1523	1545	0.98
14	15	0.0078	1.5	10.9	0.4	2	23	1701	1723	1700	1723	0.96
15	15	0.45	87	5.3	3.6	3	23	1984	2006	1983	2006	0.90

Sequence Information

Coding Sequence: ATGGCTAATCTCAAGATGAAATGTTCGGGAGTAAGAAGTCCTCCGATCGGATCTCCGGGGAGGACGGTTTTGAGAGTTACCAATAAAGACATAAACAGGGAAACAACTAACTTATTCAGAACACAACTTAGAATAGGAACCTGGAATGTGCAAAATCGCCGTTGTAGCAGCAACTCCGAAATGTCCCAAATGGAGACTCAAAATCAAATGAAATCCGAAGCTGGTGATCTAGAAGAATCCAGTCAGGTTGAATCGAATTCAGCACCTCATATTTGTCCTTATTGTGACTATGCCAGTGATAGTGAAATGAGAATTCAAGCTCACATGCTTGCCCAGCATGGTTCCAGTACGCAACCTGAAACGCCTCAACAAGAACCAGCTCTTCATTGTCCTTTATGTCAAGAAATTTCCAAAGATCGAACTACTTTGGAACGACACGTCATGCAGATTCATTCCGTCAATAGCGAAGGTCTCCAGAGATTATTAATGCTTGTGGATCAAAGTCATTGGCTGAACCAATCGAGGACGTCGACTCCAAATAATACGAACGTTCCAAATCAAATATCCCCAACATCGGTTTCGTCCAAAGACTCATCAAAACTAGAGAAAAGTGATAGCGGATATCCCGATGAAAATCCTGAATTAATGTCGTCGATTAATGATGACAATAACGATGCTGAAAGCGAGCGGTGCGGAACCTGTTTCAAAACGTTCAAGAACATCGATGAATTATGTTTCCATCAAAATGAAACTGGACATTTGGAGATCAAGCAAACTCCGAGCGGTCCTGGATATCTGTGCTGGAAGAAAGGATGTAATCAGTTTTTTCCCACAGCTCACACGTTACAAACTCATTTTAAAGAGGTCCATGCTAAAAATTCCATCGCTAACATGTCAGTGAGCGAGAAACACGTGTACAAGTACCGATGCAACCAATGCTCCTTGGCTTTCAAGACTTTGGAAAAGTTACAGCTCCATTCTCAATATCACATGATAAGGGATGCAACTAAATGTGTACTTTGTGGACGAAGCTTCCGATCGCTGGTAGCTTTGCATAAACACGTGGAGAGTGTCCATTCTGAGTTGACCGACGAAGAACTGAACGCTTATAAACAAAGTTTAATGAACAATCCGTTGTTGCTTGCTGGTCTTCAAGGTCAGATCTTGGACAGTTCCACCAATGACATTTTGAAGAAGGAAAGCTTGAGAGGAGAGGAAAATGAAAGTACTGAATGTGATGACAGTAAGGAACTAAGCCAATCACTGGACGATAGTATACAAAATGACGGAGAGAACTCTGATGACAGTATAATTTATAAAGATCAACAGTTTTTAGAAGACTATCTGAACAGTCAGGCTATGGCTGAAGATAGTTACAATGATCCTACGAGAAAGTATAAGTGTCATAGATGCAGAGTTGCTTTTACTCGACAAAGTTACCTGACTGCTCACAACAAGACTTTATTGCATAGAAAAGGAGAAAAATTAAGCTACCCAATGGAGAAATATCTTGATCCGAACCGACCGTATAAATGCGACGTTTGCAAAGAGAGTTTCACCCAGAAAAATATACTGTTGGTACATTACAACTCTGTAAGTCATTTACACAAACTTAAGAGAGCTATGCAGGAACAagctaataataataacaacactCCGGTCTCGACCAGTTTGGGTTTAACACAAGGCCTATCATTAACACCGAAAAGCTCTAATATTGACGACGATGACAAAAAGAAGTATCGTTGTAACATCTGCAAGGTGGCCTATACTCAAGGCAGCACGCTTGATATTCATATGAGAAGCGTTTTACACCAAACCCGAGCGAGTAAGTTGCAAGATCTCGCTATGGCCGGTCAGATTGATCTGACGAAACCGCTGATAGAACAGCCGGATGCCGGGCAGTCTCCGAAACAAACTTCGCCGTCGCCCGGAGGTGGGGATGCGCCAAAACAACCCTGCCCCACCCCTCCGTCGCCAGGTATGGCAGGTAGTCTGGGGTTGAGTTGTCCCAAGTGCGGTGCGATCTTCGTTAGCGCGGAACAGTTGAACGCTCACCAGCTGTACTGTATATTCGCCGCTCCTATGGCAATATTTCACGGCGATGACCCAGATCAAGATCCAACAGTACGCGCTATGTCCAATAAAAAGGGTTCACCCATCTATAAACATCTTCTCGAAGGATACGGATTTGATTTAGTGATGCAGTATAATGAGAGCCATCAAAGAAGACAACGACAAGCGGAAAAAGAGAAAGCGGAGGCAGAGGAGAAGCTGAAGGAACAAGCGGCTGCTGCTGCCGAAGAAGGTGCCGTTGAACTGACGATGGAAACAACCGAGCTACAAGAGATTAAGGACGAGACGCCTGTAGCTGAAGTGGAGAAAACGTGCGAAGAAGATGCCGCTAGTTTGCCTGAAGTGAGTAAATCTACGTGCCAAACGTGCAATAAAGAGTTTTCAAGTGTGTGGGTGTTAAAAAGCCACTGCGAGGAAGTGCATAAAGACTTGGTGCCGTTAGAATATCTCGAGAAATACGCacaacaactcaaaaacgaaATCGAAAAGAAAACTGTGGTGGTAACCGCTGCCACTAGCTCCACGACAAATACCACGTCTCGTGTTACGACGCCTACGACTCACACGGTTGACACTCCGAACCCAGAGACCGATTCCACTCCTGATAAAGACGTTGACGAATCCAAGGAAGCTCTTCACGTTAAACTAAATCTTCAAACACCACCAGAAGCGACTTCGACAGCTCCCAGCACACCGACAAGCAGCACCACGCCGGCTAGCTCCACAGACTCCCTGTCTGCGAATCTACAAGCGATGCTCGCACAAACGATGGCTCAAAATCCGATGGCTTTAGCTCAGCAGATGTCCGAAATGCAGGCAGCTCTCAGTGTGATGCATTTACAACAGATGAATTTCAATCCTGTGGTGCAAATGATGGGGATGGGTTTGCCTTTAGGATTGAATGCTTTAGCGGCCATGAATCTGCAACCACCTTTGGTGCCGTTGATGATGCCCCCACCACCTTTCGATCCTATGACGCAGTTTGGACCGCAGGACCAGCAGACCATGCTCGCAAAACAACAAGCCGCCATCATGCAACAACAAGCTGTGGCCAATGCCGCCAATCAAAAACGGGCTCGCACGAGAATCACCGACGATCAACTGAAGATATTGCGTTCTCATTTCGACATTAATAATTCACCTTCCGAAGATCAGATTCACGAAATGGCCAATCAGAGTGGGCTCCCGCCGAAAGTGATCAAACACTGGTTCAGAAACACCTTGTTCAAGGAGAGACAAAGAAATAAAGACAGTCCTTATAACTTTAACAATCCCCCATCCACGACTTTGAATTTGGAGGAGTACGAGAAAACTGGCGAGGCGAAAGTGCTTCCCTTGAATAATTCATCGGGAAGTAGCTCGGATGAAGCAAATAAGAGTAAAGAAATGTGTTCGCCTGCACCAACATGCGTACCTCAACATGCGGAAATCAAACAGGAAATTAAGGAAGAACCTGCTGACGAACACATTcagcaacaaaaacaaaatgaatcTTTGGAAGAAAAacctcaaaatatatttaacttgcCAGTCAACTTGCAACCTCCTCAAAGTCCTGCTACATCGATAGCTTCAACAGAAAGCATGAACGTTTCATCACAACCATCCACTCCGAATAATCTCACCTTGACCTCCATCATCGCCTCTCAGCTGGGAGACACTCTCACCACCAGTACTCCCACCTTAAACATGGCTGCAATGCAAGCCCATCACGGTCTCTCGAATCCGATGCTTCCTCCACCTAAATTAAACCAGCAAAACTTTCCCAACCCTAACAACCTCCAGGGAATGTTACCTCTGACTCCAAACCGATGTCTCAGTCCGACTAGAGACTACTCCAATCCAGGAAGTCAAGGTTCTAGTGGTTCTACAGGTAAACGTGCCAATAGGACACGATTCACCGACTACCAGATCAAAGTACTGCAAGAATTCTTTGAAAACAACGCTTATCCCAAAGACGACGATCTGGAATATCTATCAAAGCTCTTGAATTTGAGCCCTAGAGTGATTGTTGTGTGGTTTCAAAACGCTAGGCAGAAGGCTCGAAAAGTATATGAAAATCAACCAGCCGTTGATCCTGCTCCGGGAATCGATGAAGCAGGAGCCAATCGTTTTCAAAGAACTCCCGGCTTAAACTATCAGTGCAAAAAGTGTTTGTTGGTTTTCCAACGTTATTATGAATTGATCAGGCATCAAAAAACTCATTGTTTCAAGGAAGAAGATGCTAAAAGAAGTGCACAAGCACAAGCTGCTGCAGCTCAAATTGCTGCTGTTCTCAGTTCTGAAGACTCCAACTCCAGCACCACGGTGGAACAAGGGCAACAACCGATACAGACTCAACCACAAAATCTAGTGAATCCTCAAACTCCAAACTTGAGTCAGGCTCTCAGTCCGAGTCAACCGAACGCCCCAACAACGCCTACTCCAAATCAAACGGTTGGCAACTTCCCCAGTTCCTCACCTACACCCTCCGAAACCAAAGAGGGGACTTTTCAGTGTGACAAATGTAATTTGGTGTTTCCCCGATTTGAACTGTGGAGGGAGCACCAGCTCGTCCACTTGATGAATCCGAATTTGTTTCCATCTTATCCTCCGGACAGTCCGTTTGGGATCCTGCAGCAGCACGCTCAGCTGCAACAGTTAAACGCTAATCTGGGCGAAGTATCTAAGCAACAACCAACAAGTCAAAATACTCAAGTACAACCTCCAAATGTTCCACATCCACTGATAAATATGCTGAACAATGTTACCGGTCAGAAACGCAAAGCGGAAGAGTTTGGGGATGGTGAAAGCGACACCAGTGATCAGCCCAAAGATAAACGCTTAAGAACGACAATTTTACCGGAACAGTTGGATtatctataccaaaaatatCAAATCGAGAGTAACCCGTCTCGAAAAATGTTGGAAAACATCGCTCGTGAGGTTGGTCTGAAAAAACGCGTTGTCCAAGTGTGGTTTCAAAATACCAGAGCTAGAGAGAGGAAGGGTCAGTTCAGGGCACACACACAAGTCATCAATAAGAGATGTCCGTTTTGTccagctctgttcaaagtgaaAAGTGCTTTGGAATCCCACTTGACAACCAAGCACGCCGACCAATGCGCTAGAGGAGAGATCAACATTGATGCTCTCCCTGATGAAGAAGTGAGCTTGGAGAGTTCTCCGAGTTTATCGAGCGGAAATGATGGCAAATATCAACAGCAAAATCCGAACTTGATGCCTCCGTTATTTCCTTCGTTGCATCCAGACATGGAATCCtcgattaaaaaatattacgaagAAAGCATGAAGCGATACATCAATGAGCTTCAGCAGCACGCATCTTCTTCTAACGGAGATAAATGCGAGATTAAAAGTGAAAAGGGGGAAAGTGGGGAGATCCCTTTGGACCTATCCAAACCGGTTGACCTTTCGAGACCAATGAAAGTCTCCATGGAGCATGAGAGGAACTTATGCGATCCTGGGCCATTAACTGATTTAAGCGAACGTTCTTTATGTGACGAACGCAGTGACTCTATGTCTGAGACCACAGAATACATTGATGATGATAGTAATCCTACTTCTCCAGCCAGTAGTACTCAGAGCAATACCCAAAGACATCTGAACGCATCAGGGGGCTCCCAAGGTGGAACCAAACGTTTTAGAACCCAAATGAGTCCCACCCAAGTGAAAATAATGAAGAGTCTGTTCGGAGATTACAAAACGCCGACGATGGCGGAATGTGAAAGTTTGGGACGTGAAATAGGTCTTCCTAAAAGGGTGGTGCAGGTTTGGTTTCAAAACGCTCGCGCCAAAGAAAAGAAGGGTAAGATGGCCTTACAAAAGGTCCTGGGGCAGCCGGAAAACGACACACCCTCTCTACCCGAAGACTGCAAGTTCTGTAACTTCAAGTACTCGCATAAATACTCCGTTCAAGACCACATTTTTACCAAAAGTCACATAGCTAACGTTCGCATGCATCTGGAGGCACAGGGTTCCAAAGATAACACAGAGAGCGCTGGTGAATTCCAAGTCCCTCCTCTTCCGAGTGGGTCTGGTTCACTACCGACTTCCGAGTCCCAACAAAATCAGTCAGCACCGGGTCAAGGCCAAATGAACAACAACGCCCATCTTCAGCTTCTGCAGATGGCAGGCATGCAAATGCCCGGTCCCAAAACCCAGGAGCAGGAGGAGAGTCCAGAAAGTTTGTTCCAGCAGCTCTACGCAATGGGTAACAACGCGAATTTCGGCGTCCAGAATCAGTATGTGCACCACGCCATGTTCGGAGCCAACGCAAAGAACATGGGAAACAACGAGTTCAGAACTCCCGAGAGGGAAACCCAGTATCAGATGGAGACAAGACATGGAAGAAAAGATAAGAACAGTGAATGTAGGGGGGTGGAGAGAACAGATCGTATATTGGAGGAGAAGGAGGAAACAGTTGAGAAGGCAAAACATCACCAACAATTATGA
Protein Sequence: MANLKMKCSGVRSPPIGSPGRTVLRVTNKDINRETTNLFRTQLRIGTWNVQNRRCSSNSEMSQMETQNQMKSEAGDLEESSQVESNSAPHICPYCDYASDSEMRIQAHMLAQHGSSTQPETPQQEPALHCPLCQEISKDRTTLERHVMQIHSVNSEGLQRLLMLVDQSHWLNQSRTSTPNNTNVPNQISPTSVSSKDSSKLEKSDSGYPDENPELMSSINDDNNDAESERCGTCFKTFKNIDELCFHQNETGHLEIKQTPSGPGYLCWKKGCNQFFPTAHTLQTHFKEVHAKNSIANMSVSEKHVYKYRCNQCSLAFKTLEKLQLHSQYHMIRDATKCVLCGRSFRSLVALHKHVESVHSELTDEELNAYKQSLMNNPLLLAGLQGQILDSSTNDILKKESLRGEENESTECDDSKELSQSLDDSIQNDGENSDDSIIYKDQQFLEDYLNSQAMAEDSYNDPTRKYKCHRCRVAFTRQSYLTAHNKTLLHRKGEKLSYPMEKYLDPNRPYKCDVCKESFTQKNILLVHYNSVSHLHKLKRAMQEQANNNNNTPVSTSLGLTQGLSLTPKSSNIDDDDKKKYRCNICKVAYTQGSTLDIHMRSVLHQTRASKLQDLAMAGQIDLTKPLIEQPDAGQSPKQTSPSPGGGDAPKQPCPTPPSPGMAGSLGLSCPKCGAIFVSAEQLNAHQLYCIFAAPMAIFHGDDPDQDPTVRAMSNKKGSPIYKHLLEGYGFDLVMQYNESHQRRQRQAEKEKAEAEEKLKEQAAAAAEEGAVELTMETTELQEIKDETPVAEVEKTCEEDAASLPEVSKSTCQTCNKEFSSVWVLKSHCEEVHKDLVPLEYLEKYAQQLKNEIEKKTVVVTAATSSTTNTTSRVTTPTTHTVDTPNPETDSTPDKDVDESKEALHVKLNLQTPPEATSTAPSTPTSSTTPASSTDSLSANLQAMLAQTMAQNPMALAQQMSEMQAALSVMHLQQMNFNPVVQMMGMGLPLGLNALAAMNLQPPLVPLMMPPPPFDPMTQFGPQDQQTMLAKQQAAIMQQQAVANAANQKRARTRITDDQLKILRSHFDINNSPSEDQIHEMANQSGLPPKVIKHWFRNTLFKERQRNKDSPYNFNNPPSTTLNLEEYEKTGEAKVLPLNNSSGSSSDEANKSKEMCSPAPTCVPQHAEIKQEIKEEPADEHIQQQKQNESLEEKPQNIFNLPVNLQPPQSPATSIASTESMNVSSQPSTPNNLTLTSIIASQLGDTLTTSTPTLNMAAMQAHHGLSNPMLPPPKLNQQNFPNPNNLQGMLPLTPNRCLSPTRDYSNPGSQGSSGSTGKRANRTRFTDYQIKVLQEFFENNAYPKDDDLEYLSKLLNLSPRVIVVWFQNARQKARKVYENQPAVDPAPGIDEAGANRFQRTPGLNYQCKKCLLVFQRYYELIRHQKTHCFKEEDAKRSAQAQAAAAQIAAVLSSEDSNSSTTVEQGQQPIQTQPQNLVNPQTPNLSQALSPSQPNAPTTPTPNQTVGNFPSSSPTPSETKEGTFQCDKCNLVFPRFELWREHQLVHLMNPNLFPSYPPDSPFGILQQHAQLQQLNANLGEVSKQQPTSQNTQVQPPNVPHPLINMLNNVTGQKRKAEEFGDGESDTSDQPKDKRLRTTILPEQLDYLYQKYQIESNPSRKMLENIAREVGLKKRVVQVWFQNTRARERKGQFRAHTQVINKRCPFCPALFKVKSALESHLTTKHADQCARGEINIDALPDEEVSLESSPSLSSGNDGKYQQQNPNLMPPLFPSLHPDMESSIKKYYEESMKRYINELQQHASSSNGDKCEIKSEKGESGEIPLDLSKPVDLSRPMKVSMEHERNLCDPGPLTDLSERSLCDERSDSMSETTEYIDDDSNPTSPASSTQSNTQRHLNASGGSQGGTKRFRTQMSPTQVKIMKSLFGDYKTPTMAECESLGREIGLPKRVVQVWFQNARAKEKKGKMALQKVLGQPENDTPSLPEDCKFCNFKYSHKYSVQDHIFTKSHIANVRMHLEAQGSKDNTESAGEFQVPPLPSGSGSLPTSESQQNQSAPGQGQMNNNAHLQLLQMAGMQMPGPKTQEQEESPESLFQQLYAMGNNANFGVQNQYVHHAMFGANAKNMGNNEFRTPERETQYQMETRHGRKDKNSECRGVERTDRILEEKEETVEKAKHHQQL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00196690;
90% Identity: iTF_00376075;
80% Identity: iTF_00376075;