Basic Information

Insect: Cosmia pyralina
Gene Symbol: THAP3
Assembly: GCA_946251865.1
Location: CAMIUE010001285.1:117178-156758[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.26 31 6.6 1.2 1 23 349 371 349 371 0.92

2 11 0.0024 0.28 13.1 1.2 1 23 378 401 378 401 0.93

3 11 0.35 41 6.3 0.2 1 23 405 427 405 427 0.92

4 11 0.14 16 7.5 0.9 1 23 432 455 432 455 0.97

5 11 0.0037 0.43 12.5 0.3 1 23 459 482 459 482 0.96

6 11 6.7 7.9e+02 2.2 0.1 2 19 494 511 494 514 0.78

7 11 1.3 1.5e+02 4.5 0.2 3 23 570 591 568 591 0.94

8 11 0.005 0.59 12.1 0.6 2 20 607 625 606 628 0.92

9 11 3.7e-05 0.0044 18.7 3.1 1 23 634 656 634 656 0.99

10 11 0.00029 0.034 16.0 2.8 1 23 663 685 663 685 0.98

11 11 0.0033 0.39 12.6 3.9 1 23 691 714 691 714 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.26	31	6.6	1.2	1	23	349	371	349	371	0.92
2	11	0.0024	0.28	13.1	1.2	1	23	378	401	378	401	0.93
3	11	0.35	41	6.3	0.2	1	23	405	427	405	427	0.92
4	11	0.14	16	7.5	0.9	1	23	432	455	432	455	0.97
5	11	0.0037	0.43	12.5	0.3	1	23	459	482	459	482	0.96
6	11	6.7	7.9e+02	2.2	0.1	2	19	494	511	494	514	0.78
7	11	1.3	1.5e+02	4.5	0.2	3	23	570	591	568	591	0.94
8	11	0.005	0.59	12.1	0.6	2	20	607	625	606	628	0.92
9	11	3.7e-05	0.0044	18.7	3.1	1	23	634	656	634	656	0.99
10	11	0.00029	0.034	16.0	2.8	1	23	663	685	663	685	0.98
11	11	0.0033	0.39	12.6	3.9	1	23	691	714	691	714	0.89

Sequence Information

Coding Sequence: ATGAGGTGCAGTGTTCAGAATTGTTCTAATGACACGAGAACAACTAACAAAAGCCATGGAATCACATTTCATATgttCCCGAAACAGCTGGACCTCCGCGCTGCTTGGGTTGAGGCTCTCGGCATGTCTGACTGGGAGCCCAAAGACAGAAGCACCATATGCTCCGAACACTTCAGGAGTGATGACATCTATGAGACGAAGGGTGGGTTGAGAAAAATAAAGTGTGGAGCAGTACCTGTTGTGATGACTGTGTGCCGAATATGCCTTGCAATGGACAGAAAAATGTATCACATAAGAGAATTAAAACTGGATCAAATGTATGAGCAGATCACTGGATTGAtgACTAGTTCAGAAGAGCGTCTACCGCAGCGTGTGTGCTGGGAATGCGCCGCTCGTCTGAACTCGGCGTGCCGCTTCAGAAATAAGGCTCTACGGAGTGATGCGTTGCTACATGGTATGCTGCAGATAGACACTTATATAAAAATCCGCGACATAAAATCGATAAACCGAAAACACAACCACCTCACTTCTAACTTAATACATCAGATATACGAGAATGATGACTTTGATCTACGCATCAAAGACTTATCTAGTATTAAAACGGAGGAAATACCGGACACTTCCGATATTATACCAATTGTTAGTGAAGATATTAGCGAAGAAATTGATGTAAAAAGCCTAGCACCTATTAACGAAGTCGAAATCAAAGATGAAAGTAGCAATAATGAGATATTTTTTGAAGAATACGATCATTttgatgatgaagatgataaGGTTTTAAGTGAAGTTTATGTTGAGAAGAAAGAGAAGGTTAAAGTTAAGAAGAAGAGAGAAAAAGTTGTGAAAAAAGTAAAGGCGAAGAAGGTCGAGGAAGAAGATGACCCTGACACTACTAGTgataagtacaaaaaaaacgaTGTAAAACGACGTCGCAACACCGAAGCTTTCGACGAGTCGTTATTCACAATCACTTCACTAACATACGACCAGCAAATAGAAGAGATACTGAAAAGACAAGAGGGTTACAACTACACCAGCGCTCCTTATAAATGTACGATATGTTATCGAGGGTTCCAGATCAGGGATCGGTTTACCGCGCATTCTGTGAGGCATACTGAGcAATGCGGTGCCTACGAATGTTTTATTTGCAAAACTAGACTAAAAACAAGTCGTGCGCTAAGGAAACATTTAACGGCACAACATACAGAACAATATAGCTGTAAGGGATGTCCGTTTGTCACTAGGAATCGAGGTGTAGCGAGGGAACATGAGAAATGGCATGCGGGGACTAAATACCAGTGTCCGCACTGTGCTAGTGAGTTTGATAAAATAACAACCTACATGGGTCATATTCGTATAAAGCACGTTTCGGATTTCGTGTGTGAGCTCTGTGGGTATACGTTTGTCAGTGAGAAGGGAATCGCAGTCCATAAGAAGAAGAAACATCGGATTGATAAAGCGTTAACACTAGAAGGGCCATACTGTGAGCTGTGTGACGTCAAGTTCGTGTCGGAGGAGGCTCATGACAGACACCTGAAGTTATCTTCAAAACATAGCAGTGATCATGACCCtaaccGAATCCGGAATGACTCACAAAGCATGAACGCAGAACGCAACGGGCGCGTAATGAGACGCATAGAGAGGAGACCGGTCATACATCCGCGCCTACCAAGTGACAGCGACCACGAACCTCACACACCCGTCAACTGCGAACAGTGCGGCATGCAACTCCGCGACCTGCGAGTGTACGCGCAACACTTTCGTCGAGCGCACCCGGACAAGAACCGAACCAAGTACCCCGCGATGAAGACCCCATGTATGTGTGAGCAATGCGGCAAGATATTCCAGAGCATGGCCCTCCTAAAAGACCACATGTGGGTCCACACCGGTGAAAAACGCTTCAAATGTGACCGATGCACTAAAAGTTTCACCCAGAAAACCAACCTAGTGTTCCATATGAGGGTCCACAGTGCCACGCGACCGAGCTACGAGTGTCCGCTGTGCGGGAAGCACTTCGCGTTCTTCAACAATAGAAGACGACATATGTTTATCCACACTGGCCTGAAACCCTTCAAATGTGACAATTGCGGTAAATGTTTCACAACAGCGGGCGAACACAGGGCGCATGTCGAACACGTGCATCTCAAGAAGCCATGGCCCAAGCGAGCTAGACAGAGGAACAGAGACTGGAAGTGTGATGACCCCAGCATTGAGGACTGA
Protein Sequence: MRCSVQNCSNDTRTTNKSHGITFHMFPKQLDLRAAWVEALGMSDWEPKDRSTICSEHFRSDDIYETKGGLRKIKCGAVPVVMTVCRICLAMDRKMYHIRELKLDQMYEQITGLMTSSEERLPQRVCWECAARLNSACRFRNKALRSDALLHGMLQIDTYIKIRDIKSINRKHNHLTSNLIHQIYENDDFDLRIKDLSSIKTEEIPDTSDIIPIVSEDISEEIDVKSLAPINEVEIKDESSNNEIFFEEYDHFDDEDDKVLSEVYVEKKEKVKVKKKREKVVKKVKAKKVEEEDDPDTTSDKYKKNDVKRRRNTEAFDESLFTITSLTYDQQIEEILKRQEGYNYTSAPYKCTICYRGFQIRDRFTAHSVRHTEQCGAYECFICKTRLKTSRALRKHLTAQHTEQYSCKGCPFVTRNRGVAREHEKWHAGTKYQCPHCASEFDKITTYMGHIRIKHVSDFVCELCGYTFVSEKGIAVHKKKKHRIDKALTLEGPYCELCDVKFVSEEAHDRHLKLSSKHSSDHDPNRIRNDSQSMNAERNGRVMRRIERRPVIHPRLPSDSDHEPHTPVNCEQCGMQLRDLRVYAQHFRRAHPDKNRTKYPAMKTPCMCEQCGKIFQSMALLKDHMWVHTGEKRFKCDRCTKSFTQKTNLVFHMRVHSATRPSYECPLCGKHFAFFNNRRRHMFIHTGLKPFKCDNCGKCFTTAGEHRAHVEHVHLKKPWPKRARQRNRDWKCDDPSIED

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01441464;
90% Identity: iTF_00449181;
80% Identity: iTF_00374200;