Basic Information

Gene Symbol
-
Assembly
GCA_963682025.1
Location
OY821518.1:250172440-250176564[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.4 1.2e+02 6.1 1.1 3 21 503 521 501 525 0.92
2 9 0.00086 0.26 14.5 0.7 3 23 548 569 546 570 0.94
3 9 5.4 1.7e+03 2.6 0.2 1 23 586 609 586 609 0.92
4 9 0.067 20 8.6 2.8 1 23 614 638 614 638 0.93
5 9 0.00024 0.075 16.2 2.3 1 23 719 742 719 742 0.96
6 9 0.27 82 6.7 0.1 1 21 747 767 747 768 0.94
7 9 0.072 22 8.5 4.0 2 23 832 852 831 852 0.95
8 9 5.2e-07 0.00016 24.6 1.3 1 23 858 881 858 881 0.98
9 9 0.11 35 7.8 0.9 1 14 908 921 908 923 0.91

Sequence Information

Coding Sequence
ATGGAGCACGATTTGGATGACGCGCATCTGTGCATTAAATGCAGACATACAATAGTTGGTCTGGAAAACTATATACAGCATCGCAAACAAAATTGTAGCAATCCCACAACTACAACGCACAATCCAATAAAACTAATATCCACGAATACCACTGCCacgcaacagcaacagcagcggACGGAAGTAACACCGGCCATAACTTATGAACCTTATACCTTCAATGAACCTGAACCGTCCAGTTCAACAAGTCAGGGTGGTAAAACTTCAAAGACGCTGGGGGAAAGCTATGATTTACCTTATGAACTGGGCGCAGATGTATTCTTCTCATCTCTACAACTACAAAGTGTACAATCCTCGGTGGGCCAAAATGTTCAACCGACTAGTGGTGGCAAGACTGGTAGTTCCCTGCAGACAGGCCAGTTGCAACGACAAAAATCATTGCAACAGGACTCAGAACATTCTACGACTGCAGAAGAAACTTGGATTGATGCACATGCCACGAATACAGAAACCCATCATGACAGCAGTGATCGCTTGTTAAAGGCTGTTAGTGATATGGTGGAAACGAAAAAACCCTATGATCCTTTATATAAGCCCATAACATTTGAGCATGAGTCTCCAGATGGCTCAGAAGATGACGAAGAAGATGAGCTGGATGTTGATgttgaagatgatgatgatgaagatgaagacTTTGATCCAATGGTAGAGGCTCACGCCTGTGGTGGCAAATGGAAATTACCTTTGATGCGTCAGTCTCCACCGGTGGTGCCCATGTCTCATACGGGTGGCAAATGGAAACCCGAAAACCGACCTAATCTTCGTGTAGCCCATACACAATTATCACGACTATCGCCAAATTGGGATGATCATATCGATGACATGGATGCCCAAGAAGGTCAACATCCCCCCTCTGATCATACTAAGGGTAAATGGGTACCAGGTACAAAGTTACAAAGATTAGAATACAAAGAGGTTGTGGAATTGGCTAAATGTAACAGTGGCACTAAAGATTATTGGTGTAATATCTGCTGTCGTAAATTGAAAAGCAAATCAATATATGAGAACCATTTGAAAACCAGTTATCATTTGAAGAGAGCCGAACCAGAGCAACAACTAGAAAAAGCTGCCATTAAAGAGCTACCAAGAGAggatataaataaaagtttttctttaactGAGTTCAAACCACTCTCAGTTACGATTACCGCTAATAGCAAAAAGAGAAAAAGACGATCTACTTATTTAAAGTGCAGTCTCTGCAAATATGTCATGGCTAGACATTTAATTGGGAAACATTTGATATCCCACTATCATTACCGGCGCATGCAACTTCAACCAAGCATATCGTTACACATGGTTTTGGATAACATACATGCCATTGTTTTACAATCACCCTTTCAATGTCGACCTTGTCGTTTTTATGCCAATACCGAGGAAGCTTTTCTACTGCATTGGAATTCCGCTTGCCACTTGTATGTTTCTGAAGGTCCTGGTCGCTTTTGGTGTTCTTATTGTCAGTTTGAATGCGAAGATAACAATCAAATGAGACGTCATCTCTTGGGTCCCGAACACAAGGAAGTGTTGTTGGCCATTAACCGTTCGGTGCCCATTTGTATCAGTAAGCGTTTGAGTATTGATTGTGCCAAATGTGGTGTAGGCTTTCGTTATAATTTTGAACTGAGACGTCATATCCTCAATTATCATCATGGTGTAGAATTTATGGGCAGTGCTTCGGACTCGTATCAATCAAAATTTAGGTGTCTTATGTGTCCAGATGTTTTGTCATCCCAAATTGCTATACAGCGTCATGAAAAATTTAAGCATtccatttcaaaatatttctgtTCCATCTGTTCGATGGAGTTTAATAATCCCTGCAAAGCAAGAAGACATCGTAAAACTTTGGAGCATAAGCAAAAAGCTTTAGCTATAAAACAAACTTTTCGAACTACCAAGGATGAGACTAAAGAGTCATTGAAAATTGAAGGGGAGGGAAACtctattttaactcatactgagAACTTAAAATATCGCGAAGTCGTTTCTGATTCCGAATTGAATTCAACAATTATTCCTGACGAATTACCTTGCACCAGCAAACAAGCAATACTTATGACTGCCAAGCCAAGACCAATTCAAGCAACAATAACTCACAAGTGTAAATATTGTCCGCAAGAGTTCATATCAAGAGAACAGCTTAAACTACATTATGAAAGAGAACATTTGGAATCTCACCATAAATGCATGAGTTGTGCTCAAACATTTATAACGGCCCAAGAGTTGGGTAGACATGCCAGAGCATGTAAACCTACCACGATATCGATAAAAGAAGGTATTCAAATAACTCAGCAAATGAGTAAAGAAACAAATGAACAGGGTGCAAAAGTATGGAATTGTGATTTATGTGAATTTAGAGCCTCCTCCGAGTCTGATATACTCTATCATCGTGTCTTTCATTCCTATGGCTGTGTAGGTAAAAACCAACTCATTAAATGCGTTTTATGTGACAAATCCTTTCGTAAGCATTCTTTACGTTTTCATTTGCGTCAGCATACAAACGAAAAGACCTTTAAATGCCAAATATGTAACAGCTCATTTTCAAGACCTTATAATCTAAAGGATCATATCAGGAAAGTTCATggtaaaataactgaaaaaaatattgttCCACCATTAGACGAAGGAGTTGTTCCAATTCgcaaagaagttaaaaaaatatatcaatgtgaTTCGTGTGAGAAAGTCTTCAAGAGCAAAAGATCAGTTCCAACTAATGGTCGGTATAGCGTGCATAATTCCGTGCTAACAATACACAAAGCTGCTAGTGTACTTGGGTTCATTAAACGGTAA
Protein Sequence
MEHDLDDAHLCIKCRHTIVGLENYIQHRKQNCSNPTTTTHNPIKLISTNTTATQQQQQRTEVTPAITYEPYTFNEPEPSSSTSQGGKTSKTLGESYDLPYELGADVFFSSLQLQSVQSSVGQNVQPTSGGKTGSSLQTGQLQRQKSLQQDSEHSTTAEETWIDAHATNTETHHDSSDRLLKAVSDMVETKKPYDPLYKPITFEHESPDGSEDDEEDELDVDVEDDDDEDEDFDPMVEAHACGGKWKLPLMRQSPPVVPMSHTGGKWKPENRPNLRVAHTQLSRLSPNWDDHIDDMDAQEGQHPPSDHTKGKWVPGTKLQRLEYKEVVELAKCNSGTKDYWCNICCRKLKSKSIYENHLKTSYHLKRAEPEQQLEKAAIKELPREDINKSFSLTEFKPLSVTITANSKKRKRRSTYLKCSLCKYVMARHLIGKHLISHYHYRRMQLQPSISLHMVLDNIHAIVLQSPFQCRPCRFYANTEEAFLLHWNSACHLYVSEGPGRFWCSYCQFECEDNNQMRRHLLGPEHKEVLLAINRSVPICISKRLSIDCAKCGVGFRYNFELRRHILNYHHGVEFMGSASDSYQSKFRCLMCPDVLSSQIAIQRHEKFKHSISKYFCSICSMEFNNPCKARRHRKTLEHKQKALAIKQTFRTTKDETKESLKIEGEGNSILTHTENLKYREVVSDSELNSTIIPDELPCTSKQAILMTAKPRPIQATITHKCKYCPQEFISREQLKLHYEREHLESHHKCMSCAQTFITAQELGRHARACKPTTISIKEGIQITQQMSKETNEQGAKVWNCDLCEFRASSESDILYHRVFHSYGCVGKNQLIKCVLCDKSFRKHSLRFHLRQHTNEKTFKCQICNSSFSRPYNLKDHIRKVHGKITEKNIVPPLDEGVVPIRKEVKKIYQCDSCEKVFKSKRSVPTNGRYSVHNSVLTIHKAASVLGFIKR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-