Cnas003449.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Contarinia nasturtii
Gene Symbol
ZEB2
Assembly
GCA_009176525.2
Location
NW:219918-223967[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 0.001 0.039 14.1 2.8 1 23 204 226 204 226 0.97
2 16 6.4e-06 0.00024 21.0 0.8 1 23 278 300 278 300 0.96
3 16 2.8e-05 0.001 19.0 0.7 1 23 306 328 306 328 0.99
4 16 3.8e-07 1.4e-05 24.9 0.1 1 23 334 356 334 356 0.98
5 16 2e-05 0.00074 19.5 3.2 1 23 362 384 362 384 0.98
6 16 8.9e-06 0.00033 20.6 0.2 1 23 390 414 390 414 0.98
7 16 7.7e-06 0.00029 20.8 5.3 1 23 420 442 420 442 0.98
8 16 7.6 2.8e+02 1.9 3.7 1 19 632 650 632 652 0.96
9 16 0.00014 0.0053 16.8 0.4 1 23 695 717 695 717 0.97
10 16 7.5e-06 0.00028 20.8 1.0 1 23 724 747 724 747 0.97
11 16 1.2e-06 4.3e-05 23.4 3.1 1 23 770 792 770 792 0.99
12 16 1.9e-08 7.2e-07 29.0 1.2 1 23 798 820 798 820 0.99
13 16 1.6e-05 0.0006 19.8 1.3 1 23 826 848 826 848 0.99
14 16 2.4e-05 0.00089 19.2 1.8 1 23 858 880 858 880 0.98
15 16 0.0021 0.077 13.1 0.7 1 23 886 908 886 908 0.99
16 16 0.0016 0.059 13.5 7.3 1 23 914 936 914 936 0.99

Sequence Information

Coding Sequence
atggaagtaaaaaaattagatGAATTTTTAAAGAGTTGTTGTCGTATATGTTTGTCAATTTCTATCGATGAAATGATAGACTCATTGAATGTTGTCgaaaattttaacaaaacaaTCGATCAGCTGCTGTTTGAATGTGCCAATTTAAAGATGTTAGGCGTTGATAGTCATCCACGAAAACTATGCGAAGAATGCACTCAAGAACTTATAATGGTAGCAAGGTTTCGCGAGAAATGTGAAATCTCAACGGAGGCATTGAATCagataaaacgaaaaatcaacaaacaattcGATGAAAGTGAACAAGTCGATATCGGAACAGTTGGTATAAATGAACAAGAGGAGCTCAGTAACACCAACAGTAATAACGAAACGCTTTACGAGAATATCGAATACGCAGAAGATAATGTTGAATACGTTATCTATGATGAAATAGATGTAACTGAAAATCTGATACAAGATACAAATGTAGAAAGTAGCATTCAAAACGATgctgaaaatgtaaacattaaAAGTGTAGAGACACCGAAACGAAAATCATCGCCCAAAACTAAACACAAGCAAAAGAAAGAGACTGAAAGCAAACAGACGTCAAAGTCGATCATCAAACATCACTGCAAATTATGTGGAGCAGGATTTGCACAAGTGAACAATTATACCAGGCATTTGCAAACTCATAATGAACCCAACGACATTGAGTACAGCTTGGTGGACATGGAGAACTTTGAGGAAACTGTTGCGATGAGCCCAATTGGAGCCGACTTGCTGCAACCAGATTATAGTACTGGAATTGAAAGTGATCAACCCAtcgagaaaaacaaaaaggcTATTCATGCATGTCAGTTCTGTGGTCGGAAGTTTCCATCCCAATCTCTTTTGGCCACACATATTCGAATACACACGAATGAGCGACCATTTAAGTGCAGCATGTGTgcaaaatcattcaaaacaCAAGGTGCACTTGATTTACACGTTCGACGTCACAATGGAGTgAAACCATATATTTGTAACGTTTGTGATCGTGGATTCGTAGAGAGTAGCAATTTGAAGGTGCATATGAGAGTACACACGGGTGAAAAACCGCATCGATGCGTACAATGCAATAGATCTTTTTCGCGAGTATTTTTGCTGCAAATTCATATGCGTACACACACCGGTGAAAAACCGTATCAATGCCCTTACACTTCGTGTGACAAATCGTTCGCACAACAAGGAGATCTAGCCGCACATAAACGCATTCATTCAGGTGAGCGTCCACATCGCTGTAAAATTTGTCATAAAGGTTTCATAAAAAGTAGCGGGCTAACACAGCATATGCGAAGGCATTCCAGACcagtttcaaaaataaacgtGAATAGTGTGGAAAATTCGTCCGTTGACAATAAATGCATAAGCAATGAAAGTGTCATGATCTGctacaaagaaaataataaacaacatgaaattttctcaataaatttttacatttggttttttctttattttcgagaaaagaaagaaaaaatgagaattgagtttgaaaaaatttgtCGAACGTGCATGGCAAAGCCAATGACACTGGTTTCCATTTGGCCATCGAATAActtttctataaaaaatacaaacattgcACTTGATTCTTCATCATTGTCCTTTATGCTAACTACATTAATAAGATCAGAGGTTAAAATCGATGACGAATTACCAGCAAAAATGTGTCTTGATTGTATCAGCGAAATGAATCAGGCATATGCATTTGTTCAGAAATGCGAACGTTCGGAAAAAACACTACGATCTCTCTTGGAACAAACTACATGTATCCAAACAAATCCGGACACCGACAAAACTAGAGATGCATCGGTTCTATGTTCATCAAATTCAGTAAAATCTTATAATTTGAACCACAATAACTCTTACCAGTGTTCCAATTGCTATGTTGGATCTAAAACAAACACCGAATTTGAGCATCATTCATGTGATAAACAGATAGAGTTAGcagaaattgaacaaattgaatacgTTCAAACTGTGGAATGTATTTCAAGCCAACCCAAGATCACAGAAGCACTAGTCAAAGACTTCATTGCCGAGAgaacaatgaaatttaattgtgGTGATTGCAATGCAATATTCTCTAGCAAACGTTCACTTAGTTTGCATATTAACTCCCATAAATGCACACAACAAGCATATGAATGTGATATATGCCAGAAAGTGTTTATTAAGAAACGTTATCTCGTCAGACATTTACAACGAATgcatcaaatgatgaataaGGTGTGCAAAGTAACATTTGATGACGGAAATAGACCGATTCACAAGAGAAATtacaaatgtcatttatgtTCGAAAGCTTTCACAATGAGTTCGTCACTAAAGCAGCACATACGAATCCATACACAAGAAAAACCATACACATGTGAAGTATGCGGTCGTAGTTTTactcaaaattcaaatttgaggCAACATTTGATGCGCCATAAACAGAATAAGccatttaaatgtgaaaaatgttctgCAAATTTTGTTACCAAAGGCGAATTAAATTCGCACCGGCGAACACATAACGAAGATCCTCTTCTATCGCATCCATTTAGCTGTGAAGTATGCAAGTCCCGCTTCACAACTTCATCATCACTGGTAAAACATAGGCGCATCCACAGTGGTGAGAGGCCATATCAATGTGATTTATGCCCTCTTCGCTTTGCAGCGCtcagtacacagaaaaatcaTCGCCGAACTCACACAGGGGAAAAGccatttaaatgtttgaattgtcATAAATCGTTTACACAAAGATCTGATTGTATATCCCATCTTCGCACTCATACAGGAAGTCATATGTTGTATGAATGTAAACAACGCAAGCTATCGTGTACGGATTCAAAATccttaaatataaatatgataAAACATCAAATGGAACAACCGGTTGAACAATCGATTAATTTggaacgaaaatga
Protein Sequence
MEVKKLDEFLKSCCRICLSISIDEMIDSLNVVENFNKTIDQLLFECANLKMLGVDSHPRKLCEECTQELIMVARFREKCEISTEALNQIKRKINKQFDESEQVDIGTVGINEQEELSNTNSNNETLYENIEYAEDNVEYVIYDEIDVTENLIQDTNVESSIQNDAENVNIKSVETPKRKSSPKTKHKQKKETESKQTSKSIIKHHCKLCGAGFAQVNNYTRHLQTHNEPNDIEYSLVDMENFEETVAMSPIGADLLQPDYSTGIESDQPIEKNKKAIHACQFCGRKFPSQSLLATHIRIHTNERPFKCSMCAKSFKTQGALDLHVRRHNGVKPYICNVCDRGFVESSNLKVHMRVHTGEKPHRCVQCNRSFSRVFLLQIHMRTHTGEKPYQCPYTSCDKSFAQQGDLAAHKRIHSGERPHRCKICHKGFIKSSGLTQHMRRHSRPVSKINVNSVENSSVDNKCISNESVMICYKENNKQHEIFSINFYIWFFLYFREKKEKMRIEFEKICRTCMAKPMTLVSIWPSNNFSIKNTNIALDSSSLSFMLTTLIRSEVKIDDELPAKMCLDCISEMNQAYAFVQKCERSEKTLRSLLEQTTCIQTNPDTDKTRDASVLCSSNSVKSYNLNHNNSYQCSNCYVGSKTNTEFEHHSCDKQIELAEIEQIEYVQTVECISSQPKITEALVKDFIAERTMKFNCGDCNAIFSSKRSLSLHINSHKCTQQAYECDICQKVFIKKRYLVRHLQRMHQMMNKVCKVTFDDGNRPIHKRNYKCHLCSKAFTMSSSLKQHIRIHTQEKPYTCEVCGRSFTQNSNLRQHLMRHKQNKPFKCEKCSANFVTKGELNSHRRTHNEDPLLSHPFSCEVCKSRFTTSSSLVKHRRIHSGERPYQCDLCPLRFAALSTQKNHRRTHTGEKPFKCLNCHKSFTQRSDCISHLRTHTGSHMLYECKQRKLSCTDSKSLNINMIKHQMEQPVEQSINLERK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
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80% Identity
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