Basic Information

Insect: Conops quadrifasciatus
Gene Symbol: ZFY
Assembly: GCA_949752815.1
Location: OX457079.1:3126713-3129618[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 3.4e-05 0.0035 18.2 2.7 1 23 175 197 175 197 0.98

2 10 4.9e-07 5.1e-05 24.0 1.0 1 23 203 226 203 226 0.97

3 10 5.1e-06 0.00053 20.8 1.0 1 23 232 254 232 254 0.99

4 10 1.3e-05 0.0014 19.5 1.1 1 23 260 282 260 282 0.97

5 10 1.2e-05 0.0013 19.7 1.1 3 23 293 313 291 313 0.97

6 10 0.045 4.7 8.4 0.6 1 23 319 342 319 342 0.95

7 10 4.7e-05 0.0049 17.8 2.1 1 23 375 397 375 397 0.98

8 10 9.7e-06 0.001 20.0 1.8 1 23 403 425 403 425 0.99

9 10 0.0063 0.66 11.1 1.7 1 23 431 456 431 456 0.94

10 10 0.0011 0.12 13.5 0.0 1 20 462 481 462 483 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	3.4e-05	0.0035	18.2	2.7	1	23	175	197	175	197	0.98
2	10	4.9e-07	5.1e-05	24.0	1.0	1	23	203	226	203	226	0.97
3	10	5.1e-06	0.00053	20.8	1.0	1	23	232	254	232	254	0.99
4	10	1.3e-05	0.0014	19.5	1.1	1	23	260	282	260	282	0.97
5	10	1.2e-05	0.0013	19.7	1.1	3	23	293	313	291	313	0.97
6	10	0.045	4.7	8.4	0.6	1	23	319	342	319	342	0.95
7	10	4.7e-05	0.0049	17.8	2.1	1	23	375	397	375	397	0.98
8	10	9.7e-06	0.001	20.0	1.8	1	23	403	425	403	425	0.99
9	10	0.0063	0.66	11.1	1.7	1	23	431	456	431	456	0.94
10	10	0.0011	0.12	13.5	0.0	1	20	462	481	462	483	0.95

Sequence Information

Coding Sequence: atggTGCGCAGTCGTCGTTCTATTTCCAAGGAAGATGCCAGCTCCGTTTTGGCCGACAGCGGCATATCGCTTTCCTCCCCCTGCGCGGCTTCGTTGCAgccggaagaagaagaagaaataatcgAGAAGCTATGCGTTAGCAACGATGAAGAAGAGGACGAAGATGAAGATATCAACGACTCTCCAGAGGCAGAAGAAGAGGCGGAAGAGAAGGAGGAGAAGGCGGAGAAGGCGCAAAATGAGTTGAAAAAGGTGCTAAAGGCCAAGCATGCCCTCAAAATGGACGACCACGATGCCGACACTGATACAAAAGACGCTGTCGTCGCCCTTTCGTCCAGCTATTGCAACGACTCTGAAGCAGCGGGCCGCAGCTCCTCTGCCCTGTCTTCTGCCGtcaaacgacgacgacgtacGACTTCGACTGGGGCAGAAACGGCCTCCACAACCAAAGCAGCCTCAAGAGCAGCCAACAAATCAGCAAAAGCAGCCAAAACCACACAGAAGAGAGGACAACGCAAGTCGTACGAGTGTCATGTTTGTCACAAGCAATTTGGCGGCAACACCGATCTGCGCCGCCATCTGCTCATACACACCGACGAACGGCCGTTCCAGTGCAGCGTCTGCGGCAAGAGCTATCGCCAGCTGGTGAACCTCAAGAACCACACGAAGAGCGTGCACGACACGCAGCGCCAGTTCCGCTGCAAGCTCTGTCCGAAATCGTTTGCCCTGAAGGAGCGGCTGCGGCTGCACATGCGCATACACTCCGGCGAGAAACCGTACGCCTGCCATCAGTGCGACAAGAAGTTTGCACGCGGCGGTCAATTGCAGCAACATTTGGTCACACACGACGGCGGCGCCGATGTGAAGAGTGTTCATTGCAGCAAATGCTCGGCCGCCTTCTCGAGCGCCGCCAATCTGCGGCTGCACATGCGCCGGCACGAAGAGGGCCCCAACTTTCTGTGCCACATCTGCAACGAACTGTTCCTCAACGAGGTGATGCTGCGCGCACACGTCAACACGCAGCACTTCAAGCTGAAGCAGTTCGACTGCGACATTTGCAAGCAGACGATCAAAGACGACGACCCGGTCGCGCACATGAAGACGCACAGCAACGCCAAGACGCACGTGTGCGAAGTATGCAACTCGCTGTTCACACAAAAGTCGCAATACAATGTTCATATGCGCATGCACACGGGCGAAAGGCCGTATCAGTGCCGAATTTGTTGGCAATCCTTTGCTCACTCAAGCGTTCTTAAGCTTCACATACGAAAGCATACCGGCGAAAAACCTTTCAAATGTTTGCTGTGCAAGAACGATGTGGCCTTCTCGCAACTGGCCCACCTCAAGACGCACATGAAGAAGATCCACAAGAAGGAGAATCCGTACATGTGCGAAGGTTGCCAGGAATTCTTCAAGGTAAAGATCGATCTTCAGGCGCACTTGGAGTTGAGCGCCCAATGCGCTGCAATAACCAACGAACGTCTACCGGGCGATGGTGGAGGTGCTGGTGGTATGaacggtggcggtggcggtggcggcaaCGACTCTCTCTCCTCCGAAGCGGCACAACTGTCGCATCTACGTTTTCTGATCGCTTTGCTACTCAAGAAGATCTCGTCAGAGCAAAAGCTCAATCAGTTGGGCTACGAGAAACGTCTGATCGATAACGTGATCATCGCTTCGCTAAAGCTGGGCAGTCGCAAGTTCTACGACGATCACAAAATGAGCGAAATCGATCGGCTGCGTTTGAATGTGCAGGAATTCCTGGAGTGGATTGTGCCGGCGCAACTGATGGACACGTTCAAGCAGGAACAACTGGCCGTGGAGAAGGTGCTCGATAAGATCGTAACGATGTACATGAAACACAAgtga
Protein Sequence: MVRSRRSISKEDASSVLADSGISLSSPCAASLQPEEEEEIIEKLCVSNDEEEDEDEDINDSPEAEEEAEEKEEKAEKAQNELKKVLKAKHALKMDDHDADTDTKDAVVALSSSYCNDSEAAGRSSSALSSAVKRRRRTTSTGAETASTTKAASRAANKSAKAAKTTQKRGQRKSYECHVCHKQFGGNTDLRRHLLIHTDERPFQCSVCGKSYRQLVNLKNHTKSVHDTQRQFRCKLCPKSFALKERLRLHMRIHSGEKPYACHQCDKKFARGGQLQQHLVTHDGGADVKSVHCSKCSAAFSSAANLRLHMRRHEEGPNFLCHICNELFLNEVMLRAHVNTQHFKLKQFDCDICKQTIKDDDPVAHMKTHSNAKTHVCEVCNSLFTQKSQYNVHMRMHTGERPYQCRICWQSFAHSSVLKLHIRKHTGEKPFKCLLCKNDVAFSQLAHLKTHMKKIHKKENPYMCEGCQEFFKVKIDLQAHLELSAQCAAITNERLPGDGGGAGGMNGGGGGGGNDSLSSEAAQLSHLRFLIALLLKKISSEQKLNQLGYEKRLIDNVIIASLKLGSRKFYDDHKMSEIDRLRLNVQEFLEWIVPAQLMDTFKQEQLAVEKVLDKIVTMYMKHK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01201066;
90% Identity: -
80% Identity: -