Canc024994.1
Basic Information
- Insect
- Conomelus anceps
- Gene Symbol
- -
- Assembly
- GCA_948455865.1
- Location
- OX418219.1:24326319-24330366[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 18 4.4 2.1e+03 1.9 0.1 1 10 282 291 282 302 0.77 2 18 4.5 2.2e+03 1.8 2.3 2 23 396 417 395 417 0.92 3 18 0.48 2.3e+02 4.9 0.6 1 23 468 490 468 490 0.91 4 18 1.2 6e+02 3.6 2.3 2 23 582 603 581 603 0.93 5 18 0.022 11 9.1 0.1 1 21 654 674 654 675 0.91 6 18 2.5 1.2e+03 2.6 2.0 2 23 747 768 746 768 0.96 7 18 0.0012 0.58 13.1 0.4 2 21 815 834 814 835 0.93 8 18 0.00084 0.41 13.6 1.1 1 23 844 867 844 867 0.96 9 18 0.6 2.9e+02 4.6 1.8 3 23 874 894 873 894 0.96 10 18 0.29 1.4e+02 5.6 0.0 3 23 911 930 909 930 0.96 11 18 0.0012 0.61 13.0 4.7 1 23 936 958 936 958 0.97 12 18 0.0015 0.75 12.7 1.7 1 23 964 987 964 987 0.95 13 18 4.3e-05 0.021 17.6 2.7 1 23 995 1017 995 1017 0.99 14 18 0.031 15 8.6 0.6 1 21 1023 1043 1023 1047 0.91 15 18 0.00071 0.35 13.8 0.3 1 23 1066 1088 1066 1088 0.97 16 18 5.7e-05 0.028 17.2 1.0 1 22 1101 1122 1101 1125 0.91 17 18 0.34 1.6e+02 5.4 3.9 1 23 1150 1174 1150 1174 0.92 18 18 0.0016 0.76 12.7 0.6 1 23 1209 1232 1209 1232 0.93
Sequence Information
- Coding Sequence
- ATGCAGAAGGGTGACTTCTTTGGTTTGGCTAGGAAAAATGACTCTTCTCAGCTGTATTACAACTTCCCAGTGGTTAGGAACTCACAGGACTCAGACTTGAGTGGGTTTCTTACTCCAAAAGAAGCATTTCAAAACTTTAGCAATTTTCTATTTGTTAGAGTGAGAGTGATTGGGGAATTTGATTTCAGGAATACATTGGAAGAGCAGACCTCGACATATCAAATGGACTCTTCACCTGAAAATCGAAATTCAAGTGGCAGAACTATCAAAACTCACAAATTGGTTTTGCATGGAAAGAGATTAAGTGAAATAGGGAAAAGTAAAATTGTGAAAAGTGATGGCTTGATGAACAATAATACTTCCAATGCTATTATAAAAAGCGCAGAATGTGAATTAGAAAATGACACTCAGGTCAGTCCAGATCGAAATTCTCCTATCCATCTGGACAAATCAGCCGTCATTCGAATTTCACATGAACCAATAGGTATTAGTGTAGTAAATGGGATGTTTAGAATAACTGTAATCGGCTTTGAAGTTGATAAGAATTCCACTGACATTGTATCAAAACCAACATTCACTTGTTGTCTCTGTATGGATAACATAGACTCTACTGATAATATAGTTTCACACTGTAAACTTCATGAATATTTAAAAGTATCAGATAGTTGCAAATTTTGTTTTTTAAAAATGAAAGTAGAAGAATTAGAAAAACATTTAACTATTCATCGATTATTTCTTGAGCCAGTTATATGTGAGAATTTGAAGCAATTCACAACTGTTTCAAAGTTTCATCAACCTCTTCAAAAAGCTATTGCAGACTCTGTAGTTGGAAAGATGCCGGTTTTCAAATGTTCTACATGTGAAAAACTATTTCTTGCTGAGAATGATTTAGAAATTCATGTTGAAAATAATAAATGTATGGAACAACATAAGAAAAGCAATGAAAAGTCGTTGTCAACACTTCCAAGAACTCATAGCAAGAGTGATGTGCAAGTTCCAATCTCCTATAAACCTGTAGAGGTTTTCAAAAATCCAAATAGTTCTTATAGAGTAGTCATTCGTGGCTTTGTATTATGTTCAAATGGAAGTGTTGAAGAAACTTTTGTATGTTGTCTGTGCTTACAGAAGATGAAACCAAAAAATATTGTATCTCATATAAAATCACACAACCCACTTAAAGCAAGTGAATGCAAAGTGTGCTTTACAAAACATAATTCAATTAATGATTTAAAAAAGCACTTGAATGGCCATAGTTATACCCTAATTGGTCTCAATTGTCAGGATTTAACTGAATTTAAAAAAAAATGTTCTGTACAGAGTACAAAAGCTGCTCCAGTGACTGATAAGAATGTAGATGGCACCATCACAAAAAGTAAAGAATTAGAATGTATAATACCCATCTTTACTTGCAAGGATTGTTCTAAAATAATACTTGATTATAAAGATTTGGAAAATCACAAGAGTGAACATAGGATTAAAGAAATTTTGCCTAAAGATTTGAATCTTGCTCCAATCTCAAAACCTGCAATCAAGATTTTACTAGAAACTAATAATGAAATCAAAGTTGTAGTCAATGGTTTTATGATGAGAAATGAGAATCATGATGTTAATTCATTGCTAGTTGACAATGATGAGGAAGTTGTTCTCAATTCAAAGCAAGTATGTTGCATATGTTTGGAAGAAGTGAGTTCAATCAATATAGCTTGGCATTGTGAATCACATTACCCATTGAAAGCCACAGATTATTGTCAGGTTTGCTGCTTACATTTTGAGAGTACTTCAAGCTTGGAAAATCATTTGATTGATCACAAACTTGTTCTAAATGCTCTACCCTGCAATAATATGAATGAGTTCAATGCAAAACTAGCTGAAATGTCTAGTAAAGATGGTTCTTATAAGCTATTAGCAGCTACAGATATTGGAGACACCAGAAATGCAATTCAAGGATGCATTCCAGGTTTCAAATGTAATCTATGTGGAAAGATTTTTCTGATTGAGAGCAAATTAGAAGATCATATTCAATCATCTGCTTGTGTTAGTTATGTACAGCCCATAGAAGTTTTGAAGGAATCTGAGAGTGATATGGAGTTGATGATCAATGGTTATACTTTGGATTCCAGATGTGATGGAACTGATGAGATTAGTTCTTATGTCTGTTGCATCTGCTTAGGTGCATTGAAATGCAAAGCTAGCATACTGTTGCATTATAAATTGCACTACCCTTTAAAAGCTACAGATACATGTAAGTTATGCAGTTTTAACAGCGATTCTGTTTGTCTCTTGGAATCACATTTGAGACAACATAGAGTTCTATTGAATGTGATGGATCTAGCTGCTTCTACTGCATCACATTCCCGGGAGCTAATGCCAGAAATATCAAACTTTTTGAATGCAAGTAATCTACAAATGACTGATTTCAGCAATTCTGAAAATTATTTATTGAAATGCTTTGTTTGCGAGTTTTCATTTGCTGATAGAAGTATGTTTAAGAAGCACATTATTAGTGGGAAATGTATAAAATCCAAGACTTTTGCTTGTTGGAGGTGTACTAAAAATTTTAATGAGAAGAGACAGCTGACTGACCATATCAATTCATCCCATTCAGGTATGTACTCGCTGTGTCACATCTGTGGCTCCAAATTGAAGACAGCCAATATACGCAGGCATATCAGGACAATGCATGAGAAAAGGGAATCCACTCTTCTTAAACAGAGTCTCAACAAAGTGATCTGTGAAGTTTGTGGAGTTACTGTCAGCAAGTATACATTTGATCAACATATTGCTACTCATTCCTTCAACAGGAAATTTATTTGCAAAACGTGTAATAAGACATTCTCCCATATAATTTCCTACAAGACTCATTTGAAAAACCATTCATCAGAAAGACCATTTAGCTGTGAAATTTGTTCTGATACTTTCAAACGTAGTGACCATTTGGTCAGTCATAAGGCCAGGTTACACAATATTATCAAGACAAAAGATTATAAATGTGATGTTTGTTTGAAGCCGTTCAGTAGACCCAATACTTTACATATGCATAAAAGAACTCATTTGCAGTCTCAAAATTTTGAGTGTTTGCAATGCAAAGCTATATTTTCATCAGAAATGGGATTGAAGAACCACCAGACTCAAACTAGACATCTTGGAGTGGAATTTATTTCTTCAACCATTGATGAACGCAATAAAGTGAACCGGTTTGCTTGTCAGATCTGTGGTCAACGATATGGATCAATTACGAGTTTGAAAAGACATGAAAACAGTCATGATGATAGTAATGAGAATGAAGCATCTTCACTGACCTATGAATGTCCTGAGTGTCACAGAAACTATTCGTCCCAACGAAGTTTGGAGCTGCATATCATTAGGACAAATCATGCTGTTGATCGCTCTAGGTGGAAAAGAAAAGAAATACAACCACAAATTCAGACAATGCCTTTGAAAAGAGATTTTGTATGTGATCTGTGTGATTCAAGATTTCTGAAACGGTTCCATTTGAAAGTGCACAGACGAAAATTGAAACATTTTTTGACTTGCTCACTTTGCAACGATTCAACTGTTACAGATTTTCAGGAGCACAACAAAGAAAAGCACACTCCTAGTGGTAGCAGTAGTTGCACTGTTACATTCAACTGTGCTGAATGCCCAAAGAAATTCAAAAAACTAAAAATGCTAGATAATCATATAGCTCTCAAACATACTAAGCAACCGAGTGTATCCACTACATTATCTCCATCAGAGTGTGAATCAACTCCTGCTTCTAATATGATAGTCAAAACTATCATCAAAACAATCCCTTCATCTATCAGTGAATATATTGTTTCATAA
- Protein Sequence
- MQKGDFFGLARKNDSSQLYYNFPVVRNSQDSDLSGFLTPKEAFQNFSNFLFVRVRVIGEFDFRNTLEEQTSTYQMDSSPENRNSSGRTIKTHKLVLHGKRLSEIGKSKIVKSDGLMNNNTSNAIIKSAECELENDTQVSPDRNSPIHLDKSAVIRISHEPIGISVVNGMFRITVIGFEVDKNSTDIVSKPTFTCCLCMDNIDSTDNIVSHCKLHEYLKVSDSCKFCFLKMKVEELEKHLTIHRLFLEPVICENLKQFTTVSKFHQPLQKAIADSVVGKMPVFKCSTCEKLFLAENDLEIHVENNKCMEQHKKSNEKSLSTLPRTHSKSDVQVPISYKPVEVFKNPNSSYRVVIRGFVLCSNGSVEETFVCCLCLQKMKPKNIVSHIKSHNPLKASECKVCFTKHNSINDLKKHLNGHSYTLIGLNCQDLTEFKKKCSVQSTKAAPVTDKNVDGTITKSKELECIIPIFTCKDCSKIILDYKDLENHKSEHRIKEILPKDLNLAPISKPAIKILLETNNEIKVVVNGFMMRNENHDVNSLLVDNDEEVVLNSKQVCCICLEEVSSINIAWHCESHYPLKATDYCQVCCLHFESTSSLENHLIDHKLVLNALPCNNMNEFNAKLAEMSSKDGSYKLLAATDIGDTRNAIQGCIPGFKCNLCGKIFLIESKLEDHIQSSACVSYVQPIEVLKESESDMELMINGYTLDSRCDGTDEISSYVCCICLGALKCKASILLHYKLHYPLKATDTCKLCSFNSDSVCLLESHLRQHRVLLNVMDLAASTASHSRELMPEISNFLNASNLQMTDFSNSENYLLKCFVCEFSFADRSMFKKHIISGKCIKSKTFACWRCTKNFNEKRQLTDHINSSHSGMYSLCHICGSKLKTANIRRHIRTMHEKRESTLLKQSLNKVICEVCGVTVSKYTFDQHIATHSFNRKFICKTCNKTFSHIISYKTHLKNHSSERPFSCEICSDTFKRSDHLVSHKARLHNIIKTKDYKCDVCLKPFSRPNTLHMHKRTHLQSQNFECLQCKAIFSSEMGLKNHQTQTRHLGVEFISSTIDERNKVNRFACQICGQRYGSITSLKRHENSHDDSNENEASSLTYECPECHRNYSSQRSLELHIIRTNHAVDRSRWKRKEIQPQIQTMPLKRDFVCDLCDSRFLKRFHLKVHRRKLKHFLTCSLCNDSTVTDFQEHNKEKHTPSGSSSCTVTFNCAECPKKFKKLKMLDNHIALKHTKQPSVSTTLSPSECESTPASNMIVKTIIKTIPSSISEYIVS
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -