Canc059076.1
Basic Information
- Insect
- Conomelus anceps
- Gene Symbol
- PGBD3
- Assembly
- GCA_948455865.1
- Location
- OX418225.1:30815263-30825857[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 0.13 64 6.7 1.0 2 23 1439 1461 1438 1461 0.94 2 10 1.8e-06 0.00089 21.9 0.2 1 23 1687 1709 1687 1709 0.97 3 10 5.8e-05 0.028 17.2 0.7 1 23 1715 1737 1715 1737 0.97 4 10 1.6 7.9e+02 3.2 5.4 2 23 1744 1765 1744 1766 0.78 5 10 0.0043 2.1 11.3 0.6 1 23 1773 1795 1773 1795 0.98 6 10 0.0027 1.3 12.0 0.2 3 23 1802 1822 1801 1822 0.96 7 10 0.0033 1.6 11.7 4.0 1 23 1831 1853 1831 1853 0.96 8 10 3.6e-05 0.018 17.9 4.4 2 23 1859 1880 1858 1880 0.98 9 10 1.7e-05 0.0085 18.9 4.4 1 23 1883 1905 1883 1905 0.97 10 10 0.00055 0.27 14.2 1.4 1 23 1946 1968 1946 1968 0.97
Sequence Information
- Coding Sequence
- ATGTCAAAAAAACTTGATGATGAGGAAATCCTCTCCTATCTTTGTGATTCAGAACTGAGTGATCTGTCAGATGATGACAATGATATTAATCCCAATATAAGCCAACCTGCTGAGAGATATTTGGGTGCATCATCAGAGGAGTCGAATGATGAAGACCCGCAAATGCAGCCTGAGGTTGATTCCAAATCACATGGGCTTGCGAGACTTCTTACCATCCTGCCATCCTCAGATCCTGAATCTCATTTCATCAGAGAACCCTCCTTTTCTGAAGTCCAGGAAAATGCATGTGAAATGGGACCTACTTCAGAAACCTCCAGCTCATTTATTGGTGTGAGAGAGCAGCCCACACCTTCAACCTCCGCCTTGTCTATGGATGTGATTGTATCTCGTGTGTCACAAGAAACTGAGAGTCAACCAAAGAGATGCAAGGTACAGACAGCTGCAAAAAAGATGATTTGGACGAAAAAGCGTTTCAATCCGAAAGCTTTTCCTGGGCCACTCAATCTTCATATGATTCAGGTACATTCTTTACTGGCATATCCATTTGAATACTTTGATGATAATTCTTTTGATTTAATGTGCAAATGTTCAAATATTTATTCTATGGCTAAGACTGGTATTTCAATTAACACAAACCGTGTTGAGATGAAAACATTTATTGCAGTGAACTTAATAGCAAGGGGTTTGAATTATCCCAGATTAAGGATGTTTTGGGAGGCCTCTACAAGGCTTCCATTGATTGCTGATTCTATGTCTAGAGATAGATTTATAAGTTTGCGACAAAATATTCGTGTGGTTGACAATTTGAATCCTCCACCAAATTATGAAGACAATGCTGtttggaaaattcaaccaattattgataatgtgaggagggcgtgtttgaaccagccaagagacaataattcatactccatcagcgaacaaattatccaatttactcgtcgatgtagtatgaaacaatttgtaaaaaataaacctcgccctgtaggtctcaaaaactttgttgtcactacatcttatggcttagttctagattttattgtatatcatggtaacaaaacccagttgattaataaagagctaggcttaggtccctctataattatgacactagttcaaacacttcctccagccagttttgttttctttgacagtcatttcactactttgtctttgctgcagaagttgacagaggttggtattgaagggactggtacattaatggcaaaccgCCTGCAAGAATTAACTTGCAAGTCAGATGAGAAGCTTGATCGGGGTCAAAGTGTGGAATATGTGCGGAGTGATAATAAACTTGTTGTTGTCGAGTGGCAGGATAATAGCAAAGTTATTATTGCTTCCTCCTGCTTTGGAATTTCTCCTGAAGAGAAGATTAAACTGTGGTCCAAGGCAAAAAAACGCCATGTTGAGGTAGCATGTCCATCagttgtaaagaagtacaaccaatgcatgggaggggctgatcttcatgatcaactgatggaatcctatcaaatgtggtataaaacaacaaaatggaccctgaaatgcatactctattttcttgatttgagtgttggtaattgttgggtcaggtacatgcgtgacgccaaatcaaatcatttaaaaagaaaggacTGCATGGATCTCCTCAAATTCCGACTGGAGTTGGCTGAGGTCTTGCTATCAACTCCTGCAGTTGATAGGGTTGTCTCCAGTGACATTGATGAAGCTCAGCCAACTGTTGTGGCTTCACCAAAGTTCTATAATGTCCCCAAAAAAATTCCTGGAGCAGATAAGAGGTATGATGGCTATGACCATTGGCCTGTATCTGACGACCTGAAAACTTCCAGGAAGTGTAGGAAAGAGGGATGCACTTCCAGAACTAGATTGAGAGCTCCATTGTCTCAAGTGAGGAGTGATTACAAAGTTGAAAAAAGAAGACTGCAAAAAAGAAAGGGTAATAATAGTATACCTGGAGATAAAGAGAGCATAAAAGGAGAGTATAACGTGCTGGAAAAATCGATTATGCAAAATGAAGCTGCTACCAAGTACATGGATTGTAGTTCAGTGGGAAGTTGTTTGGAGGCGGCAACCAAAAACAATTTAGAAGCTCAAACAGCATCAGAGGCTCATGCTGCACAACATATGACATTGACTTCAAACCCTTTCGAAACAAATCCCACAAGTGTACTATTGGAGAATCGAATGTGTCAGGCGATTCCAGAAAGTTCAGAATCCAATGCTTACAGAATATTGCCAAATAATGGACCGCACACTGATAATGAACTAGTGAAATCTTCAGGACCAGCTTCAGCTGTACTGGATCCTTCATCTCAATTGATTAAAATTAAAGACAATATGTTTCTGGTGGTTCGTCCTATTACTTCAAATCAGAATAGTGCACCGTCAACTCAAACTCCTGCATTAGATTCAAATCAAGCAGCGAACAGGAAGGTTCTTGGACTGCTTGTAACGAATGGACCACATCCTGCAACTTCTACATCTGCAACCAATAATCTGCTGACTAATCAACAAAATGTGACGGTTTCAAGCTCCAATTCCATTCAGAGAAGAAATTTAACTCAATCAATAGATAGCAATAAGCTTCAGCTATTGACAGTTAATGGCTCAAACATATTAGTGCCCAATCCTACTCCTCAAACTGATGTTAGCAATTTGCTGGTGGGAAATCAATTACCAAAAGTAGATTTGAGTTTTAAACAACCGCAACTATCAATATCAGGCTCTTTCAGCAATCTACTGGCAGCCCAAAAGAGTGTGACAACTTCAAATATTAAGTCCCTTCAAACTGGAAATTCGGGCCAACCAATAGATGGCAATAATTTCAAGCTACTGACAGTTAATGGTTCAAATATATTGGTACCCAATCCTGCACCTCAATCTGCAACTAATTTGCTTCTTGGAAATCAATTACCGAAATTGGATTTGGGAAGCACCCAATCCCAATTAACGATTCCAAGCTCTGTACCTAAATCTGTAAATACTCAGCCGAAGACTTCTCCAGTGTTCATTTCGTTTCAACCTATCAGTAGAAATGCATCAGGATTGCTAGTAGCAAATGGAGCTCAATCAGCTGTGGTCAGCTCTACAACTAAAACTACAATCAACAATGTAATGACAAATAAAATAACAAATTGCATGGTTGCAACTAATAGTGAGTTGAACAACTCTACAGTTTCCACACATTCTCTCAGTGGGCTGAACTCAAATCAACATTTTTCTAAATCTATTAAGTTTACTGTGCCAAATAATCAGTTACAAAAGAGTGGAACTGTTTCAATGGATGGTTCTCATAAAAGTGGGACTTTGAGTCAACCAAACTGCAACAAGTTTGAGCTCTTGACAATTAATGGTTCTCATTTCATGATACCAGCAAATCCTACATCTCAATCTTCAGTAGGAAATGTGGTGACTGGAAATCAAGACTTGAGTACAACTGTTAGAGGTTTAGCAGCACAAAAGAGCTTTGTGACATCGACCATTTCTTCATTTTCTGCTCAATCTCCTAATTCTGTTCCAAATGTTTCGCCTCAATCTTTTCTTATAGCTCTACCAAGTAGTTCAGCTCCCAGTGGACCAGTTTCTAAGAAATCATTTGAACCATCTAATTTGTTGAAACAACGCCTTCTCATGCCCCCCTCTGTTGATGCTGCTCAAGCAAAAAATCAATCAACTGGTGAAGACACAGGATATATTTTACCAACAGTTGGTCCACCTGCATTCAATTCGTCTCCAAATCTGAAACAACCTGTCATAAGTTTAATTGCATCTACATCGGATGCTTCAACATCATTGTCGAACAATGATCAGCAGAAGATTTTTGTGGCAGCAACAACGTTACTTGATAGTAAAAGAGATGAAAATGAAGTTTTTGTTGTTGATGATTATGTAACACCATCTTCCAGACCAAATAATGACGGTATGGAGAAATCAAGTGCAAACAAGCCTGTCGATGAAAGTGTTCAAAATAGTGGTTCACATACTATCAACATGAATGAGAATCCGGGAACAAAATGTTTATTCTTTATTGACAACAATGGAAAGTTGAATATTGGAACTAAATCTGACACTGAAGAGTCTTCTAGATCTTGTCCAGTTCAGAATATTACAGGTAGTAATGGAAAATTGAATCAATCGAGTCCTGCAGAATTTTCTGTCCAGAATTCTTTTGGGAATAATGGAAAGTTGAATCTTTTAATGAATTTAAATACGCTAATGCTGCCTAACTTTTCTCTCCAACAAAGCTCTACAATTAGTTCTCTTGAAAAACCAACCACTCATACAATGTTGAAATGTTCTATGTGTTTTTTCAAGTTACCGAATAAAAAACAGCTAAAAATTCATGAGCTCGTCTACCATGAAGTACCATATGTGTGTGAGTGTGGTGAGAAAATTATGTTCTATCAGTCATTTGCAAAACATAATTGTCCGTACAACGATGTTTCTCTTGATGATGTAAAAAAAGCAATATTGAATTCTAAATTTATCAAACTGAAATCTGTAGTTGATTCCAACAAAGATGGAAAAACTAGAAACAAAAATGGAAAAATTAGAAATAAAGATGGAAAGTCTGCAATAGTTGATCAATCTATCGAAGATAAAAAAATCATTGAAGCTGATGTTTCTGTAGAAGGTGACAATCAAGATACAGAAATGCTGGAAGATGTACCGTGTAAGGTTGATGTCAATCAAGATTTAGAATCTGAAATAGCTGGTGTTTCTATGGAAACATCTGATGACAATCAATATATAACAGATTTAGTATGTGATGTCGATGGTGATTCTGTTGATCCATTAGCTGATGCATCTGATAATGATGAGCCAGCAATGTTGGCGCCTGAAGTGATTCTTGGTGATGAATCTGCAGTCGAACGTAGAATTGAGGCACTGATGATGGCAGTCAAAGGAAATGGAAGACGAGGGAATGGAAGGAAAAGAAAAACATCTGTCGAAGAAAGTGAATCTACAGTGAGTTGTCCCCTTTGCAAGCAGCGTGTGAAAAATTTGGAAGAACACATCCTTGAAAAGCATAAGTTTGTTTGTGGTGTATGCGACAAGGAATTTAATAGAAAGAGTAACTTGTTGACTCATTTAGCAGTTCATTCTGATAGGAGAGATTTTGCGTGTAAGTTGTGTGACAAGACGTACAAAACGAAAGCTGGGTTGTACATTCATGAGCGGAGCCATGCAATACAACGTCGTCCGAGTTGTGAATATTGTAGCAAGACGTTTCTACTGACCACTCATCTCCAAACGCATGTATTCAAACACCATGCAGATGTGGCACGCAAGTACAAATGTGACATGTGTGATGAGGAGTTTGTGATAAGGAGACTGTGGATGCGTCATAAAAATCGACACAAGGAAGAGGGGATTTTGTGTATGGTGTGTGGACGTAGGTTTGTGTCTGAAGAGGAACTCAAGCAACACTCGTCGGTGCACACTAAGCAAGATTTAAACCACGATTTTTGTTGTGATCTATGTGGACGAACTTTCCGCGAACTACACTTTCTCACCGCACATCGCAACGCGCATGCCCGGAAAAATAATCAATGTAAACACTGTAAAAAACGGTTCAAGAACGATGCTGAGTTGAAATCCCATATGCTCACTCATAAAGGCTACAAGTGCAAAGAGTGTGACAAAGTATTCACGAAAAACACTCACCTTAAGGAGCATAGTAAAGAACATGTGAAACGGTCAATTAAATGTGATGTGTGTGATCAGTGGTTTTTGACTGACATTGCATTGCGATTGCATGTCTCCAAAGTGCATAATTTGAAGCAAAATGTATGTGAGAATAGACGAATATTTGAATGTGAGTTTTGCGGTAAGACTTACATCACACGATCGAAAATGCTCACGCACAAAGTGACGCATGCCGATTATTATATACCGTTGTACAACCGTACGAGAAAGCGAGTCTGCTCTGAATTTGATAAATCGAATGTTGAATAA
- Protein Sequence
- MSKKLDDEEILSYLCDSELSDLSDDDNDINPNISQPAERYLGASSEESNDEDPQMQPEVDSKSHGLARLLTILPSSDPESHFIREPSFSEVQENACEMGPTSETSSSFIGVREQPTPSTSALSMDVIVSRVSQETESQPKRCKVQTAAKKMIWTKKRFNPKAFPGPLNLHMIQVHSLLAYPFEYFDDNSFDLMCKCSNIYSMAKTGISINTNRVEMKTFIAVNLIARGLNYPRLRMFWEASTRLPLIADSMSRDRFISLRQNIRVVDNLNPPPNYEDNAVWKIQPIIDNVRRACLNQPRDNNSYSISEQIIQFTRRCSMKQFVKNKPRPVGLKNFVVTTSYGLVLDFIVYHGNKTQLINKELGLGPSIIMTLVQTLPPASFVFFDSHFTTLSLLQKLTEVGIEGTGTLMANRLQELTCKSDEKLDRGQSVEYVRSDNKLVVVEWQDNSKVIIASSCFGISPEEKIKLWSKAKKRHVEVACPSVVKKYNQCMGGADLHDQLMESYQMWYKTTKWTLKCILYFLDLSVGNCWVRYMRDAKSNHLKRKDCMDLLKFRLELAEVLLSTPAVDRVVSSDIDEAQPTVVASPKFYNVPKKIPGADKRYDGYDHWPVSDDLKTSRKCRKEGCTSRTRLRAPLSQVRSDYKVEKRRLQKRKGNNSIPGDKESIKGEYNVLEKSIMQNEAATKYMDCSSVGSCLEAATKNNLEAQTASEAHAAQHMTLTSNPFETNPTSVLLENRMCQAIPESSESNAYRILPNNGPHTDNELVKSSGPASAVLDPSSQLIKIKDNMFLVVRPITSNQNSAPSTQTPALDSNQAANRKVLGLLVTNGPHPATSTSATNNLLTNQQNVTVSSSNSIQRRNLTQSIDSNKLQLLTVNGSNILVPNPTPQTDVSNLLVGNQLPKVDLSFKQPQLSISGSFSNLLAAQKSVTTSNIKSLQTGNSGQPIDGNNFKLLTVNGSNILVPNPAPQSATNLLLGNQLPKLDLGSTQSQLTIPSSVPKSVNTQPKTSPVFISFQPISRNASGLLVANGAQSAVVSSTTKTTINNVMTNKITNCMVATNSELNNSTVSTHSLSGLNSNQHFSKSIKFTVPNNQLQKSGTVSMDGSHKSGTLSQPNCNKFELLTINGSHFMIPANPTSQSSVGNVVTGNQDLSTTVRGLAAQKSFVTSTISSFSAQSPNSVPNVSPQSFLIALPSSSAPSGPVSKKSFEPSNLLKQRLLMPPSVDAAQAKNQSTGEDTGYILPTVGPPAFNSSPNLKQPVISLIASTSDASTSLSNNDQQKIFVAATTLLDSKRDENEVFVVDDYVTPSSRPNNDGMEKSSANKPVDESVQNSGSHTINMNENPGTKCLFFIDNNGKLNIGTKSDTEESSRSCPVQNITGSNGKLNQSSPAEFSVQNSFGNNGKLNLLMNLNTLMLPNFSLQQSSTISSLEKPTTHTMLKCSMCFFKLPNKKQLKIHELVYHEVPYVCECGEKIMFYQSFAKHNCPYNDVSLDDVKKAILNSKFIKLKSVVDSNKDGKTRNKNGKIRNKDGKSAIVDQSIEDKKIIEADVSVEGDNQDTEMLEDVPCKVDVNQDLESEIAGVSMETSDDNQYITDLVCDVDGDSVDPLADASDNDEPAMLAPEVILGDESAVERRIEALMMAVKGNGRRGNGRKRKTSVEESESTVSCPLCKQRVKNLEEHILEKHKFVCGVCDKEFNRKSNLLTHLAVHSDRRDFACKLCDKTYKTKAGLYIHERSHAIQRRPSCEYCSKTFLLTTHLQTHVFKHHADVARKYKCDMCDEEFVIRRLWMRHKNRHKEEGILCMVCGRRFVSEEELKQHSSVHTKQDLNHDFCCDLCGRTFRELHFLTAHRNAHARKNNQCKHCKKRFKNDAELKSHMLTHKGYKCKECDKVFTKNTHLKEHSKEHVKRSIKCDVCDQWFLTDIALRLHVSKVHNLKQNVCENRRIFECEFCGKTYITRSKMLTHKVTHADYYIPLYNRTRKRVCSEFDKSNVE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -