Basic Information

Gene Symbol
-
Assembly
GCA_029603195.2
Location
JAQSLO010000044.1:7842305-7843690[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 7 1.4 1.5e+02 3.8 0.6 2 19 40 57 39 62 0.92
2 7 3.3e-06 0.00035 21.5 2.9 1 23 178 201 178 201 0.96
3 7 0.0001 0.011 16.8 1.1 1 23 207 230 207 230 0.96
4 7 0.041 4.5 8.6 0.7 1 23 339 366 339 366 0.94
5 7 0.006 0.65 11.3 0.6 1 23 372 395 372 395 0.94
6 7 4.3e-05 0.0046 18.0 3.0 1 23 401 423 401 423 0.98
7 7 0.00011 0.012 16.7 2.7 1 23 429 452 429 452 0.97

Sequence Information

Coding Sequence
ATGAATGACATAATGGAAGATGATGGTTATGCTGGTTATGAAGCAGATCCTTTGGATgataattttcaagttaaatgCGGCCAAATTCTTGTTTCAGCtactcaaaaattttccttGCGTTGTGCAGGATGTGATTTGGAATACGAtagttttaaagattttataaatcacTGTATAGAAATGCATTCATTTACAGATTTTGAAGTTGATACAAAAAACAATGCAACAGGTCGCAAAtcagtttttgaattaaatgaggATTCTAATATGAGTAGTTTAATCACGATGGGCCCGCCAGCTTGTGGCAACTTAGATATAAGTAATGGTAGCTCTCAGAATTTCTCTGAAAAAGGAAACAGGAGTTTCAAAGATCAAAATCAAGATAGCGATATTTGTATGGAAAGTGCAAAACCAAGAAAACCACTTATAACTTTAAAACCAATTGAGTCATTACAAAAGAAAACCTTCAGTAAAAGTGAGGATGATTTTCGATCACCACGTAAAAGGGTTTATCAACAATCAGAATGTCGTTTCCAATGTAAATATTGCGACAAAAGTTATCCATATTCAAGTTCGTTAAGTAAAcacagaaatttatttcataatgaaataaaaaagtatcAATGTTCATTTTGTGATAATCGTTTCACagatgaaatatatttaatacgaCATCAGAAAGCGCGCCATAAAAATGCTTTGCAACCGTATGCAGAAGacccaataatattattagaggATTTTGGTGATAATTTAGgagataataaaaacaataccgATAATTCTAAATATCCCTCGGTTAAAAATGAACCAATGGAAAATTATATTGCCAACGATGATCATAATATGcaaaaacacattaaaaataatggtaatcATAACGATAGCGAAATTAAGTCAAAAAACAATACTTCATttagaaaagataaaattatctattcaaaatcaaattttcaagttcaaaataatataagtggTCAATCTAGTAAAAGCCCTAAGATGCCAAAAGTGATTTATAAATGTACAATGTGTCcagaaagtgaaaatattacatTTCGATCAAAAAAAGAATGGCAGGCACATGAAAATCATGCCCATCTTCAGCCTGAAAAATTCCGTTGTCAAATATGTAACGTTGGCTATCCCTCAAAAAAACTGTTCCAGGATCATGAACAAGAAAAACATCAGGATCAGAGACCTTACAAATGTCCAATATGCTTCTTTGCTTTTAAAGAACGTAAGCACTTGATGCGACACGAAAAGGTGCATACAGGTGAAAAACCTTTTAAATGCCCATTTTGTGCAGAACAGTTCACAAGAAAAGACGCACTCAAAACACATCATTCAAAAGAGCATCCTGATATGCCAATTgatcatattaaataa
Protein Sequence
MNDIMEDDGYAGYEADPLDDNFQVKCGQILVSATQKFSLRCAGCDLEYDSFKDFINHCIEMHSFTDFEVDTKNNATGRKSVFELNEDSNMSSLITMGPPACGNLDISNGSSQNFSEKGNRSFKDQNQDSDICMESAKPRKPLITLKPIESLQKKTFSKSEDDFRSPRKRVYQQSECRFQCKYCDKSYPYSSSLSKHRNLFHNEIKKYQCSFCDNRFTDEIYLIRHQKARHKNALQPYAEDPIILLEDFGDNLGDNKNNTDNSKYPSVKNEPMENYIANDDHNMQKHIKNNGNHNDSEIKSKNNTSFRKDKIIYSKSNFQVQNNISGQSSKSPKMPKVIYKCTMCPESENITFRSKKEWQAHENHAHLQPEKFRCQICNVGYPSKKLFQDHEQEKHQDQRPYKCPICFFAFKERKHLMRHEKVHTGEKPFKCPFCAEQFTRKDALKTHHSKEHPDMPIDHIK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-