Basic Information

Insect: Columbicola columbae
Gene Symbol: PRDM2_1
Assembly: GCA_016920875.1
Location: JADMLL010000008.1:2531147-2533706[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 2e-05 0.0016 18.7 2.7 1 23 46 68 46 68 0.98

2 14 0.00088 0.068 13.6 1.0 1 21 74 94 74 95 0.90

3 14 9.8e-06 0.00075 19.7 4.7 1 23 116 138 116 138 0.99

4 14 0.78 59 4.3 2.5 1 23 182 204 182 204 0.95

5 14 0.028 2.2 8.8 0.1 1 23 210 233 210 233 0.91

6 14 0.017 1.3 9.6 1.8 1 23 245 267 245 267 0.97

7 14 6.7e-05 0.0051 17.1 4.0 1 23 273 295 273 295 0.97

8 14 0.42 32 5.2 0.1 2 23 400 421 399 421 0.90

9 14 1.8e-07 1.4e-05 25.2 1.9 2 23 433 455 432 455 0.97

10 14 8.7e-07 6.7e-05 23.0 2.6 2 23 462 483 462 483 0.98

11 14 4.6e-05 0.0035 17.6 0.1 1 20 489 508 489 508 0.98

12 14 0.00024 0.019 15.3 5.6 1 23 517 539 517 539 0.98

13 14 0.00028 0.021 15.1 1.2 1 19 545 563 545 567 0.95

14 14 0.00069 0.053 13.9 9.1 1 23 573 595 573 596 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	2e-05	0.0016	18.7	2.7	1	23	46	68	46	68	0.98
2	14	0.00088	0.068	13.6	1.0	1	21	74	94	74	95	0.90
3	14	9.8e-06	0.00075	19.7	4.7	1	23	116	138	116	138	0.99
4	14	0.78	59	4.3	2.5	1	23	182	204	182	204	0.95
5	14	0.028	2.2	8.8	0.1	1	23	210	233	210	233	0.91
6	14	0.017	1.3	9.6	1.8	1	23	245	267	245	267	0.97
7	14	6.7e-05	0.0051	17.1	4.0	1	23	273	295	273	295	0.97
8	14	0.42	32	5.2	0.1	2	23	400	421	399	421	0.90
9	14	1.8e-07	1.4e-05	25.2	1.9	2	23	433	455	432	455	0.97
10	14	8.7e-07	6.7e-05	23.0	2.6	2	23	462	483	462	483	0.98
11	14	4.6e-05	0.0035	17.6	0.1	1	20	489	508	489	508	0.98
12	14	0.00024	0.019	15.3	5.6	1	23	517	539	517	539	0.98
13	14	0.00028	0.021	15.1	1.2	1	19	545	563	545	567	0.95
14	14	0.00069	0.053	13.9	9.1	1	23	573	595	573	596	0.96

Sequence Information

Coding Sequence: ATGGAGACGAAGAGGTGGGAGCCTATCAATGTGGAGAAAACGGGAAATAATAGTGAAATAATGAAAAGACGAAAATTCCCGAAGGAAATGGAATCCATCTCGGTGTTAAGTCCGAACGGGGCGTTGAAAAATATATACAGGTGCAAATTGTGCGGTCATAAAACGAATCGAAGTAATAACTTGAAGGCTCACTTACAAATTCACAAGAGAGTCGTGCCGTATAAGTGCGAGAAATGCGGGAAACGATACACGAGGCGACAGGACGGTAAAGATCATTTGAGAAACATCGAAATCGTGTTGGAGTGCACGGGTGGCGGGAACGGAGAGGGACAAACGAAGAAGTTGTACAGGTGCAAATTGTGCGGTCACACTTCGAACAGAAGCAACAATTTGAAGAAACACCTGAGGAGTCACGAGTCGACACAGGAATTGATTTGCGAGTCGTGCGGAGGGAAATGTATACAAAGCAACGTGATGAACTACCACGTGAAGGAGATCGAAGTGGTGACGGTTCAAGACGACCACGGGAAAAACAAAAAGAGGTTCCGGTGTAGAATCTGCGCCGAAACGTTCGAGAGAATGATCACTTGCCGGACTCACATAACGTCACATAAACCTATCAACATATACGCGTGCAAAATCTGCGGGAAGGAGTACCTGGGTGAGAAGAGCCTAAAGGAACATTCGATGAGCGCTCACGGTGAAGTCGCTCCCACTATGATCAACTTCCCGTATAAGTGCGAGTACTGCGATCAGCTGTTCGCGGAGAAAAGCGCCTGCGAGGAACATAGACAATCACACGGAGGCGAAAGGCCTTACATATGTCACACGTGCGGTTGTGCTTTCCGAACGCAAAGCTCGCTTTATATTCACAGCAAAATTCACGGAGCTTTGGGTGAAGGCGTCAAGCTCGATGTTCTGTTGGAGTGCGAATTGAATGATATTAACAAAGCGATAACCGGGGGACGTAGAAAGTATTATAAGAGACGAAGGAAAAGGATTTACGATGGAGATTGGGTGGAAGCCCAGAGTAAAAAAATTAAAAGGAAGGAAGAAAACGAGGAAAGGGATGCCGATCTTACGGGTTTGATCGACGAGAACGATATCGATTCGATAATACAGGAAGCGAATCTATTACGCGGCGTCAAAATTATTTCCGGTGAGGGTTTGAAAGGTGCCGGTTCGACGCCATACTTAGAGTGTCCATTTTGTCAGAAAGTGGTCGAGAAGTCAGCTATGAGCGATCACCTGAGTATGGAACACAATTTAGTGCCGAAGAGAATTCAGCGAACTGTCAAGTGTCACGTCTGTGACAAAACGTTCGCGAATAAGAGTTTCCTCGTACGTCACATTCGAAGGGTTCACGAGAGAGTGATCAAAGCCAAGTGTCACGTTTGCGGTAAAACATTCACGGACACGTCTAACTACAGGCAACATTTGCTCATTCACACGGGTGTCAAGTCGTACATGTGTCAGATATGCGGAAAGGGCTTCGTTCAACGTCAGGGCCTTCGGATGCATATGCCCTGTCACTCGGAGGATTATCCGTTTTCGTGTTCGCAGTGTTCGAAGCGATTCCGAAGGAAACAACACTACGAACTTCACCTGATCAAGCACACTGGAAAGAAGTCGCATCAGTGCGAAACGTGCGGAAAGTTTTTCAGCGTCAAAAACGAATTGAAGATGCACAGTTGGATTCACAAGGAGGAGTGGCCCTATGTCTGTCACCATTGCAATAAAGGGTTTAATCAGTCGTGCGGATTAAGGCTTCACCTAAAGAACCATCACGCTTTGGGAAGTTGA
Protein Sequence: METKRWEPINVEKTGNNSEIMKRRKFPKEMESISVLSPNGALKNIYRCKLCGHKTNRSNNLKAHLQIHKRVVPYKCEKCGKRYTRRQDGKDHLRNIEIVLECTGGGNGEGQTKKLYRCKLCGHTSNRSNNLKKHLRSHESTQELICESCGGKCIQSNVMNYHVKEIEVVTVQDDHGKNKKRFRCRICAETFERMITCRTHITSHKPINIYACKICGKEYLGEKSLKEHSMSAHGEVAPTMINFPYKCEYCDQLFAEKSACEEHRQSHGGERPYICHTCGCAFRTQSSLYIHSKIHGALGEGVKLDVLLECELNDINKAITGGRRKYYKRRRKRIYDGDWVEAQSKKIKRKEENEERDADLTGLIDENDIDSIIQEANLLRGVKIISGEGLKGAGSTPYLECPFCQKVVEKSAMSDHLSMEHNLVPKRIQRTVKCHVCDKTFANKSFLVRHIRRVHERVIKAKCHVCGKTFTDTSNYRQHLLIHTGVKSYMCQICGKGFVQRQGLRMHMPCHSEDYPFSCSQCSKRFRRKQHYELHLIKHTGKKSHQCETCGKFFSVKNELKMHSWIHKEEWPYVCHHCNKGFNQSCGLRLHLKNHHALGS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -