Ccol007252.1
Basic Information
- Insect
- Columbicola columbae
- Gene Symbol
- gtf3a
- Assembly
- GCA_016920875.1
- Location
- JADMLL010000003.1:17284816-17287632[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 19 0.00025 0.019 15.3 2.6 3 23 44 64 42 64 0.96 2 19 0.00023 0.018 15.4 0.1 1 23 70 93 70 93 0.95 3 19 3.2e-07 2.4e-05 24.4 3.9 1 23 99 121 99 121 0.99 4 19 0.00046 0.035 14.5 4.2 1 23 140 162 140 162 0.98 5 19 0.01 0.77 10.2 4.9 1 23 168 191 168 191 0.82 6 19 0.00046 0.035 14.5 2.8 1 23 197 220 197 220 0.98 7 19 0.0075 0.57 10.7 0.1 2 23 254 274 253 274 0.96 8 19 0.18 13 6.3 2.0 1 23 280 302 280 302 0.96 9 19 0.12 9.3 6.9 1.2 1 23 308 331 308 331 0.95 10 19 0.016 1.2 9.6 0.9 2 23 617 638 616 638 0.95 11 19 4.1e-06 0.00031 20.9 4.8 1 23 646 668 646 668 0.98 12 19 9e-05 0.0069 16.7 7.7 1 23 674 696 674 696 0.98 13 19 0.0027 0.2 12.1 2.8 1 23 708 730 708 730 0.99 14 19 0.0048 0.37 11.3 1.5 1 23 736 758 736 758 0.94 15 19 1.9e-06 0.00015 22.0 5.1 1 23 763 785 763 785 0.98 16 19 0.0032 0.25 11.8 0.3 5 20 796 811 794 813 0.92 17 19 0.00023 0.018 15.4 3.0 1 23 825 847 825 847 0.97 18 19 0.0043 0.33 11.4 2.9 1 23 853 875 853 875 0.99 19 19 0.0026 0.2 12.1 0.2 1 23 882 905 882 905 0.95
Sequence Information
- Coding Sequence
- ATGACAAAAAAGTTCTCAGAAAACATTCAAAGACCAAATAAATTAATCGGAGCACTAGCCAAGGAAAAATCGACTCGAAAAGAGGACCTCACAAAGAGAATTTGCAAAAAGTCAAAAGGAGGGATTTTCTGTGATGTCTGCAATAAGAAACTAAGATCTCGATATCATCTAAAACTCCACATGACCGTCCACACCGGAGAAAAAAATTACATATGCGGAATATGTAAAAAAGCTTATCAGCAAAAATGGAATTTGATAACTCACGTTGCGAGAGTTCATTCGAAGGAAAAACCTTTTAAATGCAACGACTGCGGAAAAGCGTTTGGCTATTCCTCTCATTTCAAAAGGCACGTTAAGACTCACTTCCTAGAAAAGATAGAAATTCCAGAAACAGTGAAGAAAAGAATTCTGAATCCGCACAAATGCGAATTCTGCGAGAAAAGTTTCGAAACCAAGTACCGGCTGGACCAACACACGAGAGTTCACACGGGGACTAGGCCCTATGTCTGCGACAAATGCGGGAAATCCTTCACCACGAAAAGGCTGTGCAAGTTTCACATGATCAAGAAACACGAGCAAGAGTCCCATTTCGAATGCGAACATTGCAAACACACTTTTCCCGATCGCTCGTCCATCGTTTTGCACTTGAAGACAGAGCATGATGTTGGTTATTTAGTAGAAAACGAGACGTCTAAAGATGATGCGCAAATATTCAGAATCGTGGAAACGATGTCCGCTCAGCCTCAACGAGAACTGGTTCCCTGCGAGGTGTGCGGTAAAACTGTGACAAGAGGATCCATACAGAAGCACCTAAACGTTCACTACAGAAACAGAATTTATTCCTGTCGCTACTGCAAAAAGGAATTTTTAGAAAGCGGTCAAAGAAGGGTACACGAACGAAAGCATACTGGCGAAAAACCTTATTTGTGCGACGTGTGTGGACGTGGACATGCTCAATACGGCAATCTATCGACCCATAAGAAACGATACCATAATTTAAGGGGTAAAAGCCCAAAAGTGTGGAAAAGTGAGGCCACTTTTTCAACCAATAAAATTTCAAATGAAAACCATGGCAATAATGGTTCCGAAGGATTCAGCGAAAGCTTTTCGGAAAACTCACAAACAACAGAACTAAGTGACTTCAACAAAACAATAGTAACTTCACGTTTGAAGGAAAACGGATCAGAAAGATTGAGAGAAAGCGAAGAGTCGTGTAGCGGTGAAGTAAACAGCCTGATCGAAACTGCTAATTCCAACCAAGATCTCATCAAAGCCGACGAAGGCTCTTCAAAATCTACTTTCGTTCTCGATCCAAAACCTGATACAAAATCAAAGTGCACCGGAAACGAAACTATAGAAGAATTCTTGAAAATAGCGAGTACGTGGGTAGACAAAAAGTTCAACGAATCTAAACACAAAAATTTTAGATTTGAGAAAAGTTGCAACTTAGAAACCTCACCCCCTTTGACAAGACTTCGCAAACAGAAGACTGCCGAAAAGATCGAGGACGAATCTTCCGAGCCCACAGATCAAGTAAGTGAATCCGAGTTTTCGGATGAGCTCACTCCGAATACTACTGAGAAGGAACCCGAAAACTCATATTGGGACACTCAGGAAAACAAAAACTTAGCCAAAGAAGTGAAAAGAAAAATGAACAAGATCATGTTTGAGAAGATAGTCGAAAGTTTAAAAAACGGTTCTTCGAGTAGCAAAGTTTTGCAAGTTGTTGATAAAGTCAAGGAAACAGTCAAAGAAAAAGGGACGGACATCTTAAAAGAATTCCTCAAGCAGATGAAATCCGTTCCGGACAACGCTGTTATGAAAACCGAGGCGGGAGTTTTGTTCTGGCATTGCTGGATGTGCGATTCCAAGCTCAAAACCAGGTATCTCTTGGCTCGACACTTACTCATTCACGAGCCGAGCGAAAATCGACCGTACAGATGCGACATTTGTCACAAAACTTTCACGCAATCCAACAATTTCAAAGAACACACCATGTCTCACAACAACGAGAATCAGTATTGCTGCGAGATATGCGGTAGCGGTTTCAGACATAAGTCCCACTTCAATTTGCACATGAGGAGACACGATCCCGCCACTGCGAAATCAGGTCTAAAAAAATACGAGTGCTCTTACTGCGGGAAAAAATTACACACAAATTATCAAAGAGCCGAACACGAAAGAACTCACACAAAAGAAAAACCATTCTTGTGTAAGGACTGCGGTCAGCAATTTGGAGCTTTGTCGACTTTGCACCGACATAAGTCCATTCACACGAACGCCAACCACCAATGTCAAATCTGTTTGAAGATATTTAGACAGAAGTCTAGTTTGAAGAGACATCAGAAAACACATTCGGGATTTCCCGATGAGAGAGTGAGCTGCGAGTGCGGGAAGACTTTCAGTCAAACTCCTTCCCTCAAGAAACACAAACTGATCTGCAAAAAAATTGTCGGACTAGTGGTCAAGCCTTTCCACTGCCTTGTCTGTTCTAAAAGATTTTTAACGAAAAGTGATTTAAAAAGGCACATAGCAACTCACGATCCCTCTAAAAGGTTTAAATGTTCCTTGTGTTCGATTTATTTAAAAACGGACGAAACGTTTAAGAGACACATGAGGAGACACGAAGAAAGTCGGACAGAATTTCCTTGTAATGACTGCCAATCTGTTTTTTACGATGTGACAACCCTAAGTAAACATATTGTTAAGGCTCATTTGAAAATAAAGCAAAATATTTGA
- Protein Sequence
- MTKKFSENIQRPNKLIGALAKEKSTRKEDLTKRICKKSKGGIFCDVCNKKLRSRYHLKLHMTVHTGEKNYICGICKKAYQQKWNLITHVARVHSKEKPFKCNDCGKAFGYSSHFKRHVKTHFLEKIEIPETVKKRILNPHKCEFCEKSFETKYRLDQHTRVHTGTRPYVCDKCGKSFTTKRLCKFHMIKKHEQESHFECEHCKHTFPDRSSIVLHLKTEHDVGYLVENETSKDDAQIFRIVETMSAQPQRELVPCEVCGKTVTRGSIQKHLNVHYRNRIYSCRYCKKEFLESGQRRVHERKHTGEKPYLCDVCGRGHAQYGNLSTHKKRYHNLRGKSPKVWKSEATFSTNKISNENHGNNGSEGFSESFSENSQTTELSDFNKTIVTSRLKENGSERLRESEESCSGEVNSLIETANSNQDLIKADEGSSKSTFVLDPKPDTKSKCTGNETIEEFLKIASTWVDKKFNESKHKNFRFEKSCNLETSPPLTRLRKQKTAEKIEDESSEPTDQVSESEFSDELTPNTTEKEPENSYWDTQENKNLAKEVKRKMNKIMFEKIVESLKNGSSSSKVLQVVDKVKETVKEKGTDILKEFLKQMKSVPDNAVMKTEAGVLFWHCWMCDSKLKTRYLLARHLLIHEPSENRPYRCDICHKTFTQSNNFKEHTMSHNNENQYCCEICGSGFRHKSHFNLHMRRHDPATAKSGLKKYECSYCGKKLHTNYQRAEHERTHTKEKPFLCKDCGQQFGALSTLHRHKSIHTNANHQCQICLKIFRQKSSLKRHQKTHSGFPDERVSCECGKTFSQTPSLKKHKLICKKIVGLVVKPFHCLVCSKRFLTKSDLKRHIATHDPSKRFKCSLCSIYLKTDETFKRHMRRHEESRTEFPCNDCQSVFYDVTTLSKHIVKAHLKIKQNI
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -