Basic Information

Insect: Columbicola columbae
Gene Symbol: Bcl11a
Assembly: GCA_016920875.1
Location: JADMLL010000009.1:4033541-4043166[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 34 0.04 3 8.4 2.5 1 23 14 37 14 37 0.90

2 34 7.3e-05 0.0056 17.0 0.5 2 23 42 64 41 64 0.95

3 34 0.014 1.1 9.8 2.0 1 23 69 92 69 92 0.95

4 34 0.046 3.5 8.2 0.6 2 23 99 120 99 120 0.96

5 34 4.6e-05 0.0035 17.6 2.2 2 23 127 149 126 149 0.96

6 34 0.21 16 6.1 0.7 1 14 155 168 155 171 0.92

7 34 1.1 87 3.8 0.2 2 21 340 360 339 364 0.81

8 34 0.00041 0.031 14.6 3.4 1 23 364 387 364 387 0.93

9 34 8.7e-06 0.00067 19.9 3.1 1 23 391 413 391 413 0.98

10 34 7.3e-05 0.0056 17.0 2.1 1 23 419 441 419 441 0.98

11 34 0.0012 0.093 13.1 2.9 2 23 448 469 446 469 0.94

12 34 0.00026 0.02 15.2 1.3 1 23 511 533 511 533 0.98

13 34 0.00019 0.015 15.6 0.3 1 23 539 561 539 561 0.97

14 34 0.0003 0.023 15.0 2.2 1 23 612 635 612 635 0.94

15 34 0.094 7.2 7.2 2.7 2 23 640 662 639 662 0.94

16 34 0.00042 0.032 14.6 0.7 1 23 667 690 667 690 0.97

17 34 0.00096 0.073 13.5 2.1 1 23 736 759 736 759 0.94

18 34 0.0021 0.16 12.4 0.6 2 23 764 786 763 786 0.95

19 34 0.00093 0.071 13.5 1.0 3 23 793 813 792 813 0.96

20 34 0.0037 0.28 11.6 0.3 3 23 821 841 819 841 0.96

21 34 2e-05 0.0016 18.7 0.5 1 23 847 870 847 870 0.98

22 34 0.16 13 6.4 5.6 2 23 879 900 878 900 0.98

23 34 2.8 2.1e+02 2.6 0.6 1 8 907 914 907 916 0.91

24 34 0.00012 0.0094 16.3 2.4 1 23 935 957 935 957 0.97

25 34 1.2e-05 0.0009 19.5 0.7 1 23 963 985 963 985 0.98

26 34 0.028 2.1 8.9 0.4 2 23 1054 1074 1053 1074 0.96

27 34 3.5 2.7e+02 2.3 6.2 1 23 1081 1104 1081 1104 0.90

28 34 0.00038 0.029 14.7 3.1 2 23 1109 1130 1108 1130 0.97

29 34 0.0018 0.14 12.6 0.5 1 23 1136 1158 1136 1158 0.98

30 34 0.086 6.6 7.3 5.9 1 23 1164 1187 1164 1187 0.95

31 34 0.057 4.3 7.9 0.3 2 22 1197 1217 1196 1219 0.88

32 34 2e-05 0.0016 18.7 0.7 2 23 1226 1247 1226 1247 0.97

33 34 0.00081 0.062 13.7 3.4 2 23 1254 1275 1253 1275 0.97

34 34 5.9e-05 0.0046 17.3 2.8 1 23 1281 1303 1281 1303 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	34	0.04	3	8.4	2.5	1	23	14	37	14	37	0.90
2	34	7.3e-05	0.0056	17.0	0.5	2	23	42	64	41	64	0.95
3	34	0.014	1.1	9.8	2.0	1	23	69	92	69	92	0.95
4	34	0.046	3.5	8.2	0.6	2	23	99	120	99	120	0.96
5	34	4.6e-05	0.0035	17.6	2.2	2	23	127	149	126	149	0.96
6	34	0.21	16	6.1	0.7	1	14	155	168	155	171	0.92
7	34	1.1	87	3.8	0.2	2	21	340	360	339	364	0.81
8	34	0.00041	0.031	14.6	3.4	1	23	364	387	364	387	0.93
9	34	8.7e-06	0.00067	19.9	3.1	1	23	391	413	391	413	0.98
10	34	7.3e-05	0.0056	17.0	2.1	1	23	419	441	419	441	0.98
11	34	0.0012	0.093	13.1	2.9	2	23	448	469	446	469	0.94
12	34	0.00026	0.02	15.2	1.3	1	23	511	533	511	533	0.98
13	34	0.00019	0.015	15.6	0.3	1	23	539	561	539	561	0.97
14	34	0.0003	0.023	15.0	2.2	1	23	612	635	612	635	0.94
15	34	0.094	7.2	7.2	2.7	2	23	640	662	639	662	0.94
16	34	0.00042	0.032	14.6	0.7	1	23	667	690	667	690	0.97
17	34	0.00096	0.073	13.5	2.1	1	23	736	759	736	759	0.94
18	34	0.0021	0.16	12.4	0.6	2	23	764	786	763	786	0.95
19	34	0.00093	0.071	13.5	1.0	3	23	793	813	792	813	0.96
20	34	0.0037	0.28	11.6	0.3	3	23	821	841	819	841	0.96
21	34	2e-05	0.0016	18.7	0.5	1	23	847	870	847	870	0.98
22	34	0.16	13	6.4	5.6	2	23	879	900	878	900	0.98
23	34	2.8	2.1e+02	2.6	0.6	1	8	907	914	907	916	0.91
24	34	0.00012	0.0094	16.3	2.4	1	23	935	957	935	957	0.97
25	34	1.2e-05	0.0009	19.5	0.7	1	23	963	985	963	985	0.98
26	34	0.028	2.1	8.9	0.4	2	23	1054	1074	1053	1074	0.96
27	34	3.5	2.7e+02	2.3	6.2	1	23	1081	1104	1081	1104	0.90
28	34	0.00038	0.029	14.7	3.1	2	23	1109	1130	1108	1130	0.97
29	34	0.0018	0.14	12.6	0.5	1	23	1136	1158	1136	1158	0.98
30	34	0.086	6.6	7.3	5.9	1	23	1164	1187	1164	1187	0.95
31	34	0.057	4.3	7.9	0.3	2	22	1197	1217	1196	1219	0.88
32	34	2e-05	0.0016	18.7	0.7	2	23	1226	1247	1226	1247	0.97
33	34	0.00081	0.062	13.7	3.4	2	23	1254	1275	1253	1275	0.97
34	34	5.9e-05	0.0046	17.3	2.8	1	23	1281	1303	1281	1303	0.98

Sequence Information

Coding Sequence: ATGGCGGAACATTTAAAGGATCACGAAACCAAAATCCCACATCCTTGCGAGTCCTGTGATAAAACGTTCGTGAACGTGTACACCTGGCACAGACACGGATTCAAGATCCACGGGAAAAAACTCGAATGCGAGGAATGCAACAAGAAATTTCAAAACGTTGACAATTTCACGTGGCACCTGAGATACGTTCACGCGGAGAAAACGCACACGTGCACCCAATGTCCATATTCCACTTCGATACGTGCCAAATTGAGGAGACACGTCGAGCGAACGCATATGAAACAATTCGTCGCGCGCTGCGACATTTGTTCGAAAGGATTCTTGGACAAGTTTTATCTTGAAGAACACAAGAACCTTCATTCGGGAGACACTCCCAACCAGTGCGAGCTTTGTGGTAAAAGTTTCCGGTTCAAAACGACTCTTCGCGCGCATAAACTTAAATTCCACGCGGACATATTCCCGTACGTGTGTAGGACGTGTAAGAAAGGATTCGCAACCAAATCGGCGAAAACACCAAAGAAAAATAGTTCTAAAGTTCAGTCATCGGAAAAACTAAAATCGAAAGAGAAAAGATGTAAAGTGCCGGAAGAAAAAGGGTCAAAGCAATCATCCGCGAGAAAGAAGAATGTTACCACCAATAATAACATCATGGACGTTTCAGAGGATAAGGTAGACGAACCTCTTTTAGTGCAGATAAAAGAAGAACCGTTTTCCTCGGACGATGACATGCCCCTAGCTGAAAAGATCAGAGCTAAACGATTGGCGGACTCGGACTCGTTAGACGTGGCGGAATTATCAGAGATCAAAGTCGAAGATATAATGAAAACCGACGAGAACATTCCCGAAAGACTAAGAGAGTCGCATAGGTTGAAGAGGAAAAAGGGCGTGGATTGTAATTTGTTACGCGAACAGATCAAGAAATTCGGTGAAGACATGGAAAAGAAATTGGATGATATGATCATTGAAGCTCAAAAAAATTTAAACGCAAAGTTACCAAAATTTCCTAGAGAGAAAACGGAGTGTCCGTTGTGCGGTGAGAAATATTTTGAAATATTAGCTCATTTAGAAAAACACGCAAGCCGAACGCCTCACAGTTGCAACAAGTGCAACAAATCCTTCACGTTCAAGGGAAAACTCATGGACCATAAGAAATTCGCCCACGGGATTAATTACGCTTGCGAAATATGCCATAAACGATTTAACCATAAGGATAATATTAGGATACACATGGCCACGCACGAAACCGAAGAGAAATACGTATGCTACATATGCGGCTACTCGACGAAACGGAAACAGTGCCTTGAAGTTCACATAATGAGACACGAAGACAAATGGGTCTGTCACTGTTCCATTTGCAATCGAGGTTTCTTCTCCTACGCCACCCTGGCCCAACACATGAACAGTCACACCGGAGAAAAACCGTTCACCTGCGATCAGTGCGAGCCAACTACTCTAATTACAACACTCTCTGGAAACATTCCAGAAAATTTCACCCGGAGCTTTATAACAATCTATTCTCTTGGTAATCACTTCGAATGCGATTCGTGCACGAAAACGTTCAGTAAAGAACTCTCACTTATAATACACAAGCGAACGCACACCAACGAAAGACCGTACGTTTGTAAAACGTGCGGAGGAGCATTCACCGCGAGGAAGTACCTTACCAAGCACATGGGTGTTCACAAAGCCAAAAATTACAAATGTCGGTTTTGTTATAAAAAATTCATGTACGTAAAAAAGGATGTAAATAAACCAGAATCTGATGATGACAAGTCACTAGCATCCCTACGTGAATTATTAAAATCGAAGAATTCAGTGAGCGTAAAGTACATATTCCCTTGTTCCATGTGTCACGAATCCTTCAAAATGAAATCGAAATTGATTCAGCATCGATACATCGAACACGGAATCGGAATCAGGTGTAAGATATGCTTCCGAACGTTTTCGAATGTATCCGCGTGTGCGACTCATCTCACGACGAAACATTCCCGGGAGGGATATCCGTGTTCCGACTGCGATTATAAGACTGTCAAAGCATCCGAGTTTAGGAATCACGTACGAAACCGACACGGAAACTGTTTGAAACTCGAAAACCAGGAGAAGAAAAACGGCGGAAGTGGGTACAACGAAGGATTTACTAATCCCAAGGAGAATGGCGAAGTCTCGGAGAGAATCGCAACAGAGAAGAAGACGATAAAAAGTAAATTCTCGTGTGACATGTGCGAGACGAGTTTCACTCTTAAAAGCAAATTGCTGAAACATAAAAACGAGAAACACGGGACCGACATAAAATGCGAGATATGCGCTCAAGTCTTCACGAGTTTGGTGTCTCTGCGAAGTCACAAATTCACAAAGCACACGGGTAAAGATAAGATTTGCGAGATATGCGGTTACTCGACGAAGAAAACGTACGATTTCAAAAGACACCAGGTGAAACACAGCAACGTGTACAGCGTCATGTGTATGGTGTGCAACAAAGGTTTCTATTCCCTGTACGAATTCAACGAACACAAAAACGTTCACACGGCCGAGAGACCGTACCAATGCGAAGTCTGCGGAATCGACTACAGCAGACGAAGCTCTCTCATTCTACACCGAAACCGAAAACATCCGGAAATCTACGACTCATCAAAACGGTGTCATATATGCAATCGGGTTTGCTTGACGAAGGAAACGATGGAATCTCACCTGAAGACACACGTCGAAGGAAGGAAACGTTACTATTGTGATATCTGCGGTAAGGGACTTCTCACGAGAGTCATACTAAAGGTTCTCAGAAGGAGTCACACGGGAGAGAAACCTTTCGATTGTAGTTATTGTGGGAGAGCATTTAGCTGTAAGAAAAATCTTTCGGTTCATATCCGCCTGCATACCGGTGATCGTCCCTACTCTTGTAAACTCTGTTGGAAAGCGTATACGAAAAGCTCGGCACTTAAGGCTCACGAAAAGACTCATATTCCGCGACAGTATAACTTCTTCAGCGTGGCTACGTATCTGACGTTCCGGCTTGAAGCTAAGACCAGCGATGACCTGACAACAGTTACAGTAAAAATAGAAGTTGAAGAGAAAGATGAATATGAGATGTTACAAGAAAGATGGACAGATTCATTAGGAGAATTGACAAACGAAAAATGTCTTTCAACCGCTTCCATTAAAGTACCCTGTAACATATGCGGAGGATTGTACACAAAAAAACTTCTACAAAGACACAAAAGAAGTCACACGTCAGCAAGAACGATGCATAAATGTGAACACTGCGAACATTCTTTCACCATGATGACGAAACTTATATTCCACAGGATGAAAGCTCACGGGATTGGTATGACATGCGTTAAATGCGACAAAACGTTCAAAAATGTACATTCGTACGCGTCGCACATGAAAAACCACACGAAAGAAAAATCTTTCATATGTGACATCTGCAAAAAAGGTTTTCTCAGCAATTATGTATTAAACGACCACATGAACCGACACACGGGAGCGACTCCACACCAGTGTCACAAGTGCGGTTCCGCGTATGCTTCCGTCAGGTCTCTGGAACGTCACCATTACAAATTCCATCCCGAGATGTGTAAGAGCAAATTGATTCGGTGCAAGAGCTGTAGCAGCGTTTTTAAAAGTAAAGTAAAACTGGAAGCCCACGAAGCAGCAAAACATCCGAACGGTTGCCGGAACGTCTGCGAGTTCTGCGGTAAAGATTTCTCATTCAGAGAATCACTCGTTCGTCACAGACGTATTCACACGGGGGAAAAACCGAAAGAGTGTTCCATTTGTAAGAAGCGATTTGCTTGCGCCAATTACCTACAGACTCACATGCGAACCCATACCGGAGAAAAACCCTACCAGTGTAGGTTTTGTTGGAAAAAGTTTAGTCAACGTTCTAGTTTAGTGACTCACGAAAAGTCGCATTTGAAAGGTTTGAAATCTTCAGGTTTGGAAATAATTCCTGTTGCGGCAGAGCCTCAACAGCCTTAA
Protein Sequence: MAEHLKDHETKIPHPCESCDKTFVNVYTWHRHGFKIHGKKLECEECNKKFQNVDNFTWHLRYVHAEKTHTCTQCPYSTSIRAKLRRHVERTHMKQFVARCDICSKGFLDKFYLEEHKNLHSGDTPNQCELCGKSFRFKTTLRAHKLKFHADIFPYVCRTCKKGFATKSAKTPKKNSSKVQSSEKLKSKEKRCKVPEEKGSKQSSARKKNVTTNNNIMDVSEDKVDEPLLVQIKEEPFSSDDDMPLAEKIRAKRLADSDSLDVAELSEIKVEDIMKTDENIPERLRESHRLKRKKGVDCNLLREQIKKFGEDMEKKLDDMIIEAQKNLNAKLPKFPREKTECPLCGEKYFEILAHLEKHASRTPHSCNKCNKSFTFKGKLMDHKKFAHGINYACEICHKRFNHKDNIRIHMATHETEEKYVCYICGYSTKRKQCLEVHIMRHEDKWVCHCSICNRGFFSYATLAQHMNSHTGEKPFTCDQCEPTTLITTLSGNIPENFTRSFITIYSLGNHFECDSCTKTFSKELSLIIHKRTHTNERPYVCKTCGGAFTARKYLTKHMGVHKAKNYKCRFCYKKFMYVKKDVNKPESDDDKSLASLRELLKSKNSVSVKYIFPCSMCHESFKMKSKLIQHRYIEHGIGIRCKICFRTFSNVSACATHLTTKHSREGYPCSDCDYKTVKASEFRNHVRNRHGNCLKLENQEKKNGGSGYNEGFTNPKENGEVSERIATEKKTIKSKFSCDMCETSFTLKSKLLKHKNEKHGTDIKCEICAQVFTSLVSLRSHKFTKHTGKDKICEICGYSTKKTYDFKRHQVKHSNVYSVMCMVCNKGFYSLYEFNEHKNVHTAERPYQCEVCGIDYSRRSSLILHRNRKHPEIYDSSKRCHICNRVCLTKETMESHLKTHVEGRKRYYCDICGKGLLTRVILKVLRRSHTGEKPFDCSYCGRAFSCKKNLSVHIRLHTGDRPYSCKLCWKAYTKSSALKAHEKTHIPRQYNFFSVATYLTFRLEAKTSDDLTTVTVKIEVEEKDEYEMLQERWTDSLGELTNEKCLSTASIKVPCNICGGLYTKKLLQRHKRSHTSARTMHKCEHCEHSFTMMTKLIFHRMKAHGIGMTCVKCDKTFKNVHSYASHMKNHTKEKSFICDICKKGFLSNYVLNDHMNRHTGATPHQCHKCGSAYASVRSLERHHYKFHPEMCKSKLIRCKSCSSVFKSKVKLEAHEAAKHPNGCRNVCEFCGKDFSFRESLVRHRRIHTGEKPKECSICKKRFACANYLQTHMRTHTGEKPYQCRFCWKKFSQRSSLVTHEKSHLKGLKSSGLEIIPVAAEPQQP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -