Basic Information

Insect: Columbicola columbae
Gene Symbol: Znf335
Assembly: GCA_016920875.1
Location: JADMLL010000009.1:3987862-3993933[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 39 0.0024 0.18 12.2 0.2 1 23 28 50 28 50 0.97

2 39 0.012 0.91 10.0 3.3 1 23 140 163 140 163 0.98

3 39 0.0002 0.015 15.6 0.4 1 23 172 195 172 195 0.93

4 39 0.0053 0.41 11.1 1.8 1 23 238 261 238 261 0.92

5 39 0.011 0.84 10.1 2.1 1 23 308 332 308 332 0.97

6 39 0.00034 0.026 14.9 0.6 1 23 336 358 336 358 0.94

7 39 0.0011 0.081 13.3 5.0 1 23 363 386 363 386 0.97

8 39 0.0002 0.015 15.6 0.2 1 23 393 416 393 416 0.96

9 39 0.0048 0.37 11.3 0.5 2 23 423 443 422 443 0.97

10 39 1.2e-05 0.00095 19.4 2.5 1 23 448 470 448 470 0.98

11 39 8.3e-07 6.3e-05 23.1 2.1 1 23 476 498 476 498 0.99

12 39 0.013 0.97 9.9 4.4 1 23 504 528 504 528 0.91

13 39 0.05 3.8 8.1 4.0 1 23 544 566 544 566 0.98

14 39 0.0049 0.37 11.2 0.5 1 23 572 594 572 594 0.97

15 39 0.041 3.2 8.3 2.7 1 23 599 621 599 621 0.98

16 39 0.00017 0.013 15.9 1.4 1 23 628 650 628 650 0.96

17 39 0.0011 0.087 13.2 0.4 3 23 656 676 655 676 0.98

18 39 0.0035 0.27 11.7 0.5 1 23 682 704 682 704 0.97

19 39 0.041 3.2 8.3 2.7 1 23 710 733 710 733 0.96

20 39 0.0069 0.53 10.8 4.1 3 23 742 763 740 763 0.93

21 39 4.3e-05 0.0033 17.7 2.7 2 23 770 791 769 791 0.96

22 39 0.4 31 5.2 0.6 1 10 797 806 797 809 0.92

23 39 1.2e-05 0.00095 19.4 1.1 2 23 945 966 944 966 0.97

24 39 0.021 1.6 9.2 0.5 1 23 972 994 972 994 0.96

25 39 8.2e-05 0.0063 16.8 3.0 1 23 1000 1022 1000 1022 0.98

26 39 0.79 61 4.3 1.8 2 23 1029 1050 1028 1050 0.96

27 39 2.4e-05 0.0018 18.5 0.6 1 23 1056 1078 1056 1078 0.98

28 39 0.0009 0.069 13.6 0.2 1 23 1084 1107 1084 1107 0.94

29 39 2.5 1.9e+02 2.7 0.2 3 23 1119 1140 1117 1140 0.84

30 39 0.0044 0.33 11.4 0.1 1 17 1146 1162 1146 1163 0.94

31 39 0.16 13 6.4 1.4 1 23 1290 1312 1290 1312 0.97

32 39 0.0042 0.32 11.5 0.2 1 23 1318 1340 1318 1340 0.95

33 39 8.5e-06 0.00065 19.9 5.5 1 23 1346 1368 1346 1368 0.98

34 39 0.24 19 5.9 2.9 2 23 1375 1396 1374 1396 0.97

35 39 0.00076 0.058 13.8 0.7 1 23 1402 1424 1402 1424 0.97

36 39 0.088 6.8 7.3 0.6 1 23 1430 1453 1430 1453 0.90

37 39 3.2 2.5e+02 2.4 0.4 2 23 1463 1485 1462 1485 0.64

38 39 0.001 0.08 13.3 0.8 1 23 1491 1513 1491 1513 0.97

39 39 0.00025 0.019 15.3 3.4 1 21 1519 1539 1519 1541 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	39	0.0024	0.18	12.2	0.2	1	23	28	50	28	50	0.97
2	39	0.012	0.91	10.0	3.3	1	23	140	163	140	163	0.98
3	39	0.0002	0.015	15.6	0.4	1	23	172	195	172	195	0.93
4	39	0.0053	0.41	11.1	1.8	1	23	238	261	238	261	0.92
5	39	0.011	0.84	10.1	2.1	1	23	308	332	308	332	0.97
6	39	0.00034	0.026	14.9	0.6	1	23	336	358	336	358	0.94
7	39	0.0011	0.081	13.3	5.0	1	23	363	386	363	386	0.97
8	39	0.0002	0.015	15.6	0.2	1	23	393	416	393	416	0.96
9	39	0.0048	0.37	11.3	0.5	2	23	423	443	422	443	0.97
10	39	1.2e-05	0.00095	19.4	2.5	1	23	448	470	448	470	0.98
11	39	8.3e-07	6.3e-05	23.1	2.1	1	23	476	498	476	498	0.99
12	39	0.013	0.97	9.9	4.4	1	23	504	528	504	528	0.91
13	39	0.05	3.8	8.1	4.0	1	23	544	566	544	566	0.98
14	39	0.0049	0.37	11.2	0.5	1	23	572	594	572	594	0.97
15	39	0.041	3.2	8.3	2.7	1	23	599	621	599	621	0.98
16	39	0.00017	0.013	15.9	1.4	1	23	628	650	628	650	0.96
17	39	0.0011	0.087	13.2	0.4	3	23	656	676	655	676	0.98
18	39	0.0035	0.27	11.7	0.5	1	23	682	704	682	704	0.97
19	39	0.041	3.2	8.3	2.7	1	23	710	733	710	733	0.96
20	39	0.0069	0.53	10.8	4.1	3	23	742	763	740	763	0.93
21	39	4.3e-05	0.0033	17.7	2.7	2	23	770	791	769	791	0.96
22	39	0.4	31	5.2	0.6	1	10	797	806	797	809	0.92
23	39	1.2e-05	0.00095	19.4	1.1	2	23	945	966	944	966	0.97
24	39	0.021	1.6	9.2	0.5	1	23	972	994	972	994	0.96
25	39	8.2e-05	0.0063	16.8	3.0	1	23	1000	1022	1000	1022	0.98
26	39	0.79	61	4.3	1.8	2	23	1029	1050	1028	1050	0.96
27	39	2.4e-05	0.0018	18.5	0.6	1	23	1056	1078	1056	1078	0.98
28	39	0.0009	0.069	13.6	0.2	1	23	1084	1107	1084	1107	0.94
29	39	2.5	1.9e+02	2.7	0.2	3	23	1119	1140	1117	1140	0.84
30	39	0.0044	0.33	11.4	0.1	1	17	1146	1162	1146	1163	0.94
31	39	0.16	13	6.4	1.4	1	23	1290	1312	1290	1312	0.97
32	39	0.0042	0.32	11.5	0.2	1	23	1318	1340	1318	1340	0.95
33	39	8.5e-06	0.00065	19.9	5.5	1	23	1346	1368	1346	1368	0.98
34	39	0.24	19	5.9	2.9	2	23	1375	1396	1374	1396	0.97
35	39	0.00076	0.058	13.8	0.7	1	23	1402	1424	1402	1424	0.97
36	39	0.088	6.8	7.3	0.6	1	23	1430	1453	1430	1453	0.90
37	39	3.2	2.5e+02	2.4	0.4	2	23	1463	1485	1462	1485	0.64
38	39	0.001	0.08	13.3	0.8	1	23	1491	1513	1491	1513	0.97
39	39	0.00025	0.019	15.3	3.4	1	21	1519	1539	1519	1541	0.94

Sequence Information

Coding Sequence: ATGAATTTTCCGTTTGTGTTTTGTTGGGACGTGGATGATCTGAAATCTGAAAAGTTGAACGAGCCACTATCTTCGGATAGTTATAAGTGCATCATTTGCGGAAAGACCTACGGGAGGGAAATGTCACTCTACGCTCACATCACAAGTCATTCCGAGGAGATATTGGTGTGCGAAAGCAAGCTGGACAATGGGAAGATACACGCGTGTAAATTGCGCGATTTCACGACGGAGAACAACAAAGCTTTCAACGGCCGCAGGAGGAAATACACGTCTTCCATGAATCCGAACAAGGAGAATCGGAGTCCGACGGAATTGACAAAGAAACCGAGAACGAGAAGTGTGAGATTGTCTTGCCTGAACGAAGATGATGGAGGAAACGGTTTCGAGGGTTCCGCGAAAGAAGACGCGATTAAACCATACCGGTGTGAGATTTGTTGCCGGAGGTACAAGGAAAAGAACGGTCTCAAGTGGCACATGAAAGTGAAACACGAGAAAACCGAAGAGAAAAGCGAATACAAATGTGACGTTTGTTCGAAAGCTTATTCGACTTTGACTCAACTTCAGGAACACGTCACCGAATCTCATCCAGAAAGTGTTAAATCGGAATCCGAGTTTGAAAATTTGGAAAAGGTTCAAATGAGCAGTAATGAAATAGTCTGCGGGGAGGATTTGAAAAGTGAGGTGAGAGAAAAAACGGGCAAAAAGAGCTGCTACGAATGTAGCATGTGCAAGAAGACATTTCGAACGAAGAAAATAATTTTATCGCATATCATGAAAACTCATCTAAGAGAATCGGACAATAAGACAGAATCATCGGATAATTTAAAAGACTCCATCGACACTAACAAGACTGACAACTTTGAAGAAGACTTTGTCGATAAGAGAAAGAAAAAGAAGAAGAGAGTCAAATTGGAAAAACCGTACAAATGCGACGAGGAGAACTGTTCGTACTCAACGACTAGATACTCACTTCTGAAAGCTCACAAATTCAAACACAACCCGTTTTACCAATGCGTCACATGTAAGGAGAAATTCTCATCTCGTGTCGAGCTCAGAGATCACATGCCCACGCATGGGGAAAGACCGTACAAATGCGATAAGTGTAACAAGTGCTACAAGGACAGCCACGGTCTCGGCTGGCACAAAAAGGTTCAACACGATCCATCCCGTTTGAAATACACGTGCGAGCTTTGCGGGAGGACATATCCCTTCGACAGTCTCCTCACTCAGCACATAAATCTGGCTCACGCCGCAGAAAAACAAAGTGTTTGCGACATCTGCGGTAAAAACGTGAGCAAGACTTATTTGTCGATGCACAGGAGAACCCACGGAGAGAAGCAATACTCGTGCGACTTCTGTCAGAAAACATTCATTGAGAAATCTTATCTCAAAAGACACAGGATGGTTCACACGGGGGAGAAACCATACGTGTGTAGCGTTTGCGGGCGTCTGTTCCGACAGCACAGCACCCTCACGATACACATGAGAACGCATACTGGAGACAGACCCTACAAATGCGTGCTGTGCGAGAACGCTTACAAGACTCATCACAATCTGAAGAAGCATTATATGAGGAGTGGTCACAAAATGGTTGATAACAACGAGAAGTTTAAACCGAAGAAAGTAAAACATAAATGCGATTACTGTTGTCTCGCTTTTAGACATCCGGTGGCTTTGGAAGCTCACAAGTCGACCCATGGAAACGAGAAACCTTTCCGGTGTGTTGTTTGTGAGAAGACTTTCAAAGTGTCGGTAGTGTTGAAGCTTCACGAATCACGTCACTCACGGAAGTTGTTCAGATGTAAGAAATGCGATTTTACATCGGAGGAAGTCAGTTCTTTCACGATCCACAAACGAAGGCATTTGGAACTTCAGAAGAAATTCGTTTGTGAGGTTTGCAAGAGACGATTCAAAACGGAAAAGGAATTGAAAGAGCATCGTGACCAACATCCGGATACTTTGCTCTGTGACGAATGCGGATTTTCGACCAATCAACCAGGAGCTTTGACTAATCACAAGAAGAAACACGGAAGAAGAGGAGACCATGAATGCGAGGTCTGCGGTTCCGTTTTCTTTCTCAAAACGGATTTATTACTACACATGGCCAAACACGGAAATTGCAGACCTTACAAGTGCAAGCTCTGTCCTGCAACTTACAAGGCAAAAAGCGGTTTATACTACCACAGGGAGTCGTGTCACCGACAGGAGAACGATGATGTCATTTGTGAGACTTGCGGGAAAGCCTTCACTTGCAAAACCCTTTTGAAGCATCATATTAAGCAGAAACATGCTTCGGAGGATTTGCTCACGTGCAAGCTTTGTTCCAAATCATTCTCGAGTCAGATCCAGCTTAAAAGACATAACAAAAGTCACGACGGAAACAGTTTATACGAATGCGAATTCTGCGGTAAAGCGTTTCCGGAGACGGAGTTTGAAGACGAATGTGATGAGGCTATCTCGACGGATTCGCCAGGTGATAAGGTTCTCAAAAGTGATGTTGCTGAGAAAACCGAAACAAAAGTTAAGAGAAAGAGAGGAAGGCCAAAAGGAAGTCGAAAGTTAAGCTCCAGGCGTAAGAAGGAAATAGAAAACCGTCTAGTCGATATAATCGAGGAAAAGTTAAATCAAAAACAAATGAACAATTCGAGTGATTCCGTGACCGAGGGAAGTCGGGAGTGCGAAACAGAAAGCGAAGAAAAGACTAATGAAGGATTAGGAGGCGAAGAAGACGAAGAAAAGAGTAATGACAAAGAGGATGAGGAAAAAGAAGGAGGAGAAGGTAAAAGTGGTAAGAAAAGAGGGAGGAAGAAATCGACGACGAAGAGGATAATCACGTGCGAGTTTTGCGGTAAAAATTTCGATAGAAAAGGCAACTACCTCGAACACAGGAGAACCCACACGGGTGAAAGGCCCTACGAGTGCGCGATTTGTCTCATGCGATTCGCATCTCACGCGGGTTTGAGTCGTCACAAGTTCGTGCATCAAGAATCGCGAACGTTTGAGTGCGAAGTGTGCAACAAGATCTTTAAACATCAGATACAGTTGAAGTATCACAAAGAGACACACACGAACACGGTTCCACTCAAGTGTGACATGTGCTCATACGCGACACTATCCAAACACTACCTGAACCTTCATAGAGCCACTCACTTGAACCGGGATCGTTTCGTATGCGGCATTTGCAACAGGGGTTTCAACTCTCGCACGTATCTCCTCGAACACATGAACAAACACTCCGGAGACAAACCCTTCCTCTGTGACATTTGCGGGAAGTCATATCCGGCTCGTTACAGTCTAGCCATCCACAAGCAGATGAAACACGATCCGAATTACAAACCCCGCGGCCGGGTTCCGTGCCAATTCTGCGGAAAGATGATCCTCAACAGGAAACAAGATTTAGTCAGACACAGAGGGATGCATACCGGAGAGAAACCTTTCGTGTGTCACTACTGCGGGAAAGCCGTTACCAACAGAGAATCTCTAAGACTCACGTCCGTCTTCACACCGGCGAGAAACCATTTTCTTGCGAGATCTGCGGAACCAACTTCGTCGTCGTTGCCCTGGTATCGTTTGTCCGATATCAGACGGAAAAGTTGTGGGAATGAGGGAACCGTGTCCGGAATTGATTCAAACGAGATGATATTTACCGGAGGCGTTGGGGAGGAAACGAACGCGCCTAAAGTTTTGAATATTCAGATAATCAACGACACTTCGAAAACGGACAGTTCCAATATTTTGAGCAAGGAAGGAAAGTCTTATACGGTGACTGAGTTTATAATTCCGAATGATTCGAAGATATTGAGAACGAAATCGGGGACTTCCGGAAAGAGAGGCAAAGTGAGAAAGACGAAGAAGGAGGCCAAGAAACACGTTTGCGAATTTTGTTCGAAGGCTTTCATGTGGAAAAGTGTTTTGGATGAACACAGGAGAACGCACACGAAGGAGAAACCGCATAAGTGTAAGGTGTGTGGCGTCGGATTCGGGTCGTATGCCGGGTTATGGAAGCATAAGGTGGTTCACGTGAACGCGAGACCTTTCGAGTGTCAGATTTGTCACAAATGTTTCAAGAGATCCGTTCAGTTGAAGTATCACATGGAGATTCACACGGGAACGGAAACGTTGAAATGCGAATCGTGCGAATACACGACCGTCTCGAGGAGATGCCTTCAACTTCATCGTGACACGCACAAAAGCAAACTGAAATTCGTGTGCAAGATCTGCAACAAGGGTTTCAACGCCAAGACGTATCTTTTGGAACATTCAAACATGCATTCGGGATTGCGTCCGTTTCTCTGCGACGTTTGCGGGAAGTCGTATCCGGCAAAAACTAGTCTCGCGTTTCATTATCAGAAGAAACACGGATCCGACAAACCGGTCGAGAAGAAACAATGCGACACCTGCGGAAAGATGATAATAAACAGAACTCAAGACATGGCGAGACACGCGAAAACTCACACCAAACAGAAGGACTTTATATGTCACGTTTGCGGACAAGGTCTCACCAAGGAGGAATCATTGAAAAGTCATCTGAAGCTTCACGCGGGTGATAAACCTTTCGCATGTGACGTGTGCAAGAAATCATTCCCCACGAAGAGCCTTTTGACATCGCATAAACGTTGTCACAAGAAAAACGCGGAAGAAGTCACGGGAAACGCTCAACAACTATTGACTACCATCGCGACTACCTACGAGAACGTTGCTCAAGTGAATAGTCCGACGAAACGGCTTCAAGTTGTGTTCGCGACGGCGGATGGAACGCCTATAAAAACAGCTTCAGAAATTATTTGTTTCAAAATAAAGAACAACGGCCTTATTTGA
Protein Sequence: MNFPFVFCWDVDDLKSEKLNEPLSSDSYKCIICGKTYGREMSLYAHITSHSEEILVCESKLDNGKIHACKLRDFTTENNKAFNGRRRKYTSSMNPNKENRSPTELTKKPRTRSVRLSCLNEDDGGNGFEGSAKEDAIKPYRCEICCRRYKEKNGLKWHMKVKHEKTEEKSEYKCDVCSKAYSTLTQLQEHVTESHPESVKSESEFENLEKVQMSSNEIVCGEDLKSEVREKTGKKSCYECSMCKKTFRTKKIILSHIMKTHLRESDNKTESSDNLKDSIDTNKTDNFEEDFVDKRKKKKKRVKLEKPYKCDEENCSYSTTRYSLLKAHKFKHNPFYQCVTCKEKFSSRVELRDHMPTHGERPYKCDKCNKCYKDSHGLGWHKKVQHDPSRLKYTCELCGRTYPFDSLLTQHINLAHAAEKQSVCDICGKNVSKTYLSMHRRTHGEKQYSCDFCQKTFIEKSYLKRHRMVHTGEKPYVCSVCGRLFRQHSTLTIHMRTHTGDRPYKCVLCENAYKTHHNLKKHYMRSGHKMVDNNEKFKPKKVKHKCDYCCLAFRHPVALEAHKSTHGNEKPFRCVVCEKTFKVSVVLKLHESRHSRKLFRCKKCDFTSEEVSSFTIHKRRHLELQKKFVCEVCKRRFKTEKELKEHRDQHPDTLLCDECGFSTNQPGALTNHKKKHGRRGDHECEVCGSVFFLKTDLLLHMAKHGNCRPYKCKLCPATYKAKSGLYYHRESCHRQENDDVICETCGKAFTCKTLLKHHIKQKHASEDLLTCKLCSKSFSSQIQLKRHNKSHDGNSLYECEFCGKAFPETEFEDECDEAISTDSPGDKVLKSDVAEKTETKVKRKRGRPKGSRKLSSRRKKEIENRLVDIIEEKLNQKQMNNSSDSVTEGSRECETESEEKTNEGLGGEEDEEKSNDKEDEEKEGGEGKSGKKRGRKKSTTKRIITCEFCGKNFDRKGNYLEHRRTHTGERPYECAICLMRFASHAGLSRHKFVHQESRTFECEVCNKIFKHQIQLKYHKETHTNTVPLKCDMCSYATLSKHYLNLHRATHLNRDRFVCGICNRGFNSRTYLLEHMNKHSGDKPFLCDICGKSYPARYSLAIHKQMKHDPNYKPRGRVPCQFCGKMILNRKQDLVRHRGMHTGEKPFVCHYCGKAVTNRESLRLTSVFTPARNHFLARSAEPTSSSLPWYRLSDIRRKSCGNEGTVSGIDSNEMIFTGGVGEETNAPKVLNIQIINDTSKTDSSNILSKEGKSYTVTEFIIPNDSKILRTKSGTSGKRGKVRKTKKEAKKHVCEFCSKAFMWKSVLDEHRRTHTKEKPHKCKVCGVGFGSYAGLWKHKVVHVNARPFECQICHKCFKRSVQLKYHMEIHTGTETLKCESCEYTTVSRRCLQLHRDTHKSKLKFVCKICNKGFNAKTYLLEHSNMHSGLRPFLCDVCGKSYPAKTSLAFHYQKKHGSDKPVEKKQCDTCGKMIINRTQDMARHAKTHTKQKDFICHVCGQGLTKEESLKSHLKLHAGDKPFACDVCKKSFPTKSLLTSHKRCHKKNAEEVTGNAQQLLTTIATTYENVAQVNSPTKRLQVVFATADGTPIKTASEIICFKIKNNGLI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -