Ccol013457.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Columbicola columbae
Gene Symbol
Zbtb41
Assembly
GCA_016920875.1
Location
JADMLL010000008.1:2518882-2522796[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 29 0.039 3 8.4 0.1 1 13 20 32 20 37 0.82
2 29 2.2e-05 0.0017 18.6 0.7 2 23 111 132 110 132 0.97
3 29 8.6e-05 0.0066 16.8 1.1 1 23 138 161 138 161 0.96
4 29 2.7e-06 0.00021 21.5 0.2 1 23 167 189 167 189 0.99
5 29 0.00011 0.0081 16.5 9.3 1 23 195 217 195 218 0.96
6 29 0.00042 0.033 14.6 2.0 3 23 227 248 226 248 0.97
7 29 0.0025 0.19 12.2 4.0 1 23 254 276 254 276 0.98
8 29 1.7e-05 0.0013 19.0 1.3 2 23 283 304 283 304 0.97
9 29 0.00066 0.05 14.0 2.4 3 23 311 331 310 331 0.95
10 29 0.018 1.4 9.5 2.8 2 23 338 360 338 360 0.97
11 29 1.8e-06 0.00014 22.0 2.2 1 23 436 458 436 458 0.98
12 29 0.00023 0.018 15.4 1.0 2 23 464 486 463 486 0.96
13 29 6.7e-05 0.0051 17.1 3.4 2 23 495 516 494 516 0.96
14 29 3e-05 0.0023 18.2 0.1 1 23 522 544 522 544 0.97
15 29 6.6e-06 0.00051 20.3 2.3 3 23 580 600 578 600 0.97
16 29 0.00015 0.011 16.0 2.7 1 23 606 628 606 628 0.98
17 29 0.024 1.8 9.1 1.9 2 22 682 702 681 702 0.93
18 29 2.3e-07 1.7e-05 24.9 1.7 1 23 709 731 709 731 0.98
19 29 0.031 2.4 8.7 0.4 1 15 744 758 744 765 0.83
20 29 0.0039 0.3 11.6 2.9 1 23 773 795 773 796 0.93
21 29 7.2e-06 0.00055 20.2 3.0 2 23 800 822 799 822 0.96
22 29 2.8e-05 0.0021 18.3 3.6 2 23 828 849 827 849 0.96
23 29 8.9e-05 0.0068 16.7 1.1 1 23 855 877 855 877 0.98
24 29 0.026 2 8.9 3.5 1 23 883 906 883 906 0.96
25 29 7.6e-05 0.0058 16.9 0.6 2 23 929 951 929 951 0.97
26 29 0.00076 0.058 13.8 4.4 1 23 957 979 957 980 0.95
27 29 8.7e-06 0.00067 19.9 0.4 1 23 987 1009 987 1009 0.99
28 29 7.7e-06 0.00059 20.1 1.7 1 23 1015 1038 1015 1038 0.98
29 29 1.5e-06 0.00011 22.3 1.6 1 23 1044 1066 1044 1066 0.97

Sequence Information

Coding Sequence
ATGAGAACTCATCACGAAAGCGCCAAGAGAATCGTTTCTGTAGAAGGAGAAAGTTCGCACAAGTGTCCGATATGTCGGAAAACGTTCAACGAAGTCAAGGACTTAGCCGAGGATCTTTATTCTCATGTGGAGGTTGAGAAGTTGGTGGAAGGCTCGGAGAAATGGGATCTAAATGTGTGTCGGATTTGCAGGAAAGAAGAAGTCATGGATAAAATGCCGAGTCACATACTCGTTCACATCGATTCAGAAAAGTCGAAGGAGGATAGCGAAAGAGGAGCTGTTAAGAAAAAGAAAAAAAGGGAATCCGTCGATGAGGACGGATGCAAATCGACTTGTCAGATCTGCGGGAAAACGATTTCTAGGAAGTATGCGATGAAACGTCATCTGGCGACTCATTCGGGCGAAAAGAAGTTCACGTGTCACCGTTGTGGAAAGCAATACGCTCAGGATTCGGGGTTGCAAAGACACGTATTAGTAACACATGAAGGCGTTCGCAAGTATAAGTGTCCCATCTGTTCGGTGGTGTTCGGATCGAATTCGGAGTTGAAGACACATCAGGACACGCACCCGGATCCGAGGCCGTTTCAGTGCGATCAGTGCGGGAAAACGTTTATAAGTCAGAAACACCTCTACCATCACAGGAAGTATCATCACACGGCGAACGGAATGCGTCAGCTGTGCAAACTCTGCAACCGCTATTTCTCATCACCGAGCGTTCTCAGGAGACATCACAAAGTCGTTCATTTGGGACTGAAAGAGTTTCAGTGTCACGTTTGCAGCGCTCAATTAAGCACGAAACACTACCTCCAAGAACATCTGAGACTCCATTCGGACGAACGACCGGAAGTCTGTTCGTTTTGCGGGAAAACATTCCAGATGATGGGAAATCTGAGACAGCACATGAAAACGCACATGGGAAAGACTCAGATATGTTACGCGTGTGGAAAAGGCTTTACGAGACGGTGTCATCTGCTCATTCACATGGCTTCCCATCGGGGTCTGGAACATCCTCAGTGTCAGCATTGCAATCAGGTTTTCCTTCTCAAAACGGATTTGGAGAAACATTTGAAGAAGGATCACAGAGGAAAAACGACGGAACAGGAAAGAAAACCGTCGGAGGTACCGGCCGACGACGTTGATGATGACGGTGGCGGTGAGTTCGCTCACGGATTGGAAGACTCCGATCTGGGACTCGAATCGAATTACTCCAAACTGAGCGAATTTGGTTCGGGTGAAGTACCGGAAGAGATTCCAAAAGTTCAAGCCGAGCCACAGAAAGCGAACGTAACAAAAGAAAAGAGATTTTTCAAATGCGACGTTTGTAAAAAAGTGTTCAACCGAAGATTTAACTTCGAACGTCACTTGTTAGTGCACTCCGGTCATACACTCACGTGTCACGCGTGTGGGAAACAATACAGGAGACAATCCGTTCTCGATAAGCACATAAAAGTCGTTCACCAGCAAATAAAACTCCCGAATCTCTGTTGCTCGTACTGCAACAAAGGATTTTCCTCGAATCAGAGCCTCGAGGATCATTTCCGGACTCACACGGGCGAACGGCCGTTCATATGTGAGATTTGCGGAAAAGATTTCAGAGCGAGACCGAATTTGATAGCGCATAAAAAAATTCACACGGGAGATTTGCCGTTCGCTTGTAACTTATGCGAGTATCGGTGTCGCCTCAAATCGACGTTCGTCGATCATTGTCAAAGGCATGAGGGCACTCGAACTTGTCTCTGTTCGATCTGTGGAAAAGGCTTCGTCAATAATTACGACCTGATGAAGCATAAGAAGACTCATTCCAAAGAAAGACGGTTCTCGTGCTCGTTTTGTAGCCTGACTTTTGTCATGAAAAGATATCTTAAGGTTCACATGAAGACTCATGCTCAGAAGTTGGAAGATTTGCTAGCATGCGGGAAAAAGAATCCGATCCAAGAAGACGACAACGATTCTATACACAAAAGGAAAAAGGAAACTTCGAAGAAGAGTCAGGTTAAAAGCGAGGACTGGAACATCATACCTAAGTCTTGGCTGAGCATAATCTCGTGCAAGCATTGCGGGAAGATCAGCTGCGCGCCAAAGTACCTGAGACAACACGAAAGACGAGCAACGTGCACGAGAATCCACCAATGCCCCGATTGCGGTCAGGCGTTCTCGAAGGAATCCAATTATACCAAACACATTAAGAGTCATACGAAGGAGAAGGCTTCCGGTGACCAGATCAAGAGATTCACGTGTAGTGTTTGCAACAAGAAATTCAAATTCGAAGACAACGGTCTGGCTCACGAGAAGATCTGTGGAAAGGGTGATTCAACGCACAAATGCTCCGTTTGCGGGAAGCGATTCGAAACGAAAGAGCTCGCGGACCAACATTGGACTAGTCATCATAGATCGTGCGTGTGTCACATGTGCGGTCAGTCGTTCAGCAAACCGGAATCTTTGAAACAGCACGTGAAAACGGTTCACGAAGAGTTCAAGATGGTGTGTCACTACTGCGGGAAAGAATTCTCGAGGAAAGCAAGACTCCAAGAACATTTGCAACATCACACGGGACAGATGGATTTCACGTGTCACGTCTGCGGGAAAGGATCGAAGAACGCATATTCGTTCAGCGTTCACCTCGCGACCCACACTCAGGAAACTCCGTATTCGTGTTCCTTCTGTCCAAGAACGTTCAAACACATGAAATACGTTTACCTTCACGAGAGATCCGTTCATCTCAAACTCAAATCCGGGAAAACTTATGTGAAACCAAAGAAACCGGGGAAAAACGTCGCTCAAAGGACATGTCCCCTGTGCAATAAGATGTTCAAACGTGAGAGCGCCATGTTGATACACAAGAGATCCGTTCACGAGGGTAAGAACGCTTACATTTGCAAGTTGTGCGGGAAAGACTTCAAGTACACGTATCTACTGTACGTCCACAAGAAGAAACATCATTTCCCCGAGTTGTGCAAGTATGTCTGCGAGTTTTGCGAGAAACCGTTTCCGGTTAAAACGGAACTTCAAAATCATTTGAGAAAGCACACCGGGGAGAAACCTTACGTGTGCGGACTCTGCGGGAAAACGTACTCGTTTCACGGCTCTCTCAACATGCACATGAAAACTCAACACGAGAACAAGAAAAATTACAAATGCGACATTTGCGGGGCTTCGTACAATTTTCAATCTCATCTGACGAGGCACATGACTGCCCACGCGGACAGATATCCGGTGGAAATTCTGTTGAAAGAGGATCCGTGA
Protein Sequence
MRTHHESAKRIVSVEGESSHKCPICRKTFNEVKDLAEDLYSHVEVEKLVEGSEKWDLNVCRICRKEEVMDKMPSHILVHIDSEKSKEDSERGAVKKKKKRESVDEDGCKSTCQICGKTISRKYAMKRHLATHSGEKKFTCHRCGKQYAQDSGLQRHVLVTHEGVRKYKCPICSVVFGSNSELKTHQDTHPDPRPFQCDQCGKTFISQKHLYHHRKYHHTANGMRQLCKLCNRYFSSPSVLRRHHKVVHLGLKEFQCHVCSAQLSTKHYLQEHLRLHSDERPEVCSFCGKTFQMMGNLRQHMKTHMGKTQICYACGKGFTRRCHLLIHMASHRGLEHPQCQHCNQVFLLKTDLEKHLKKDHRGKTTEQERKPSEVPADDVDDDGGGEFAHGLEDSDLGLESNYSKLSEFGSGEVPEEIPKVQAEPQKANVTKEKRFFKCDVCKKVFNRRFNFERHLLVHSGHTLTCHACGKQYRRQSVLDKHIKVVHQQIKLPNLCCSYCNKGFSSNQSLEDHFRTHTGERPFICEICGKDFRARPNLIAHKKIHTGDLPFACNLCEYRCRLKSTFVDHCQRHEGTRTCLCSICGKGFVNNYDLMKHKKTHSKERRFSCSFCSLTFVMKRYLKVHMKTHAQKLEDLLACGKKNPIQEDDNDSIHKRKKETSKKSQVKSEDWNIIPKSWLSIISCKHCGKISCAPKYLRQHERRATCTRIHQCPDCGQAFSKESNYTKHIKSHTKEKASGDQIKRFTCSVCNKKFKFEDNGLAHEKICGKGDSTHKCSVCGKRFETKELADQHWTSHHRSCVCHMCGQSFSKPESLKQHVKTVHEEFKMVCHYCGKEFSRKARLQEHLQHHTGQMDFTCHVCGKGSKNAYSFSVHLATHTQETPYSCSFCPRTFKHMKYVYLHERSVHLKLKSGKTYVKPKKPGKNVAQRTCPLCNKMFKRESAMLIHKRSVHEGKNAYICKLCGKDFKYTYLLYVHKKKHHFPELCKYVCEFCEKPFPVKTELQNHLRKHTGEKPYVCGLCGKTYSFHGSLNMHMKTQHENKKNYKCDICGASYNFQSHLTRHMTAHADRYPVEILLKEDP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-